Publications

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2006
Mikels AJ, Nusse R. "Wnts as ligands: processing, secretion and reception." Oncogene. 2006;25:7461-7468. Abstract
2007
Marino S, Nusse R. "Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal." PLoS One. 2007;2:e519. Abstract
2008
van Amerongen R, Mikels A, Nusse R. "Alternative wnt signaling is initiated by distinct receptors." Sci Signal. 2008;1:re9. Abstract
Morrell NT, Leucht P, Zhao L, et al. "Liposomal packaging generates Wnt protein with in vivo biological activity." PLoS One. 2008;3:e2930. Abstract
Marston DJ, Roh M, Mikels AJ, Nusse R, Goldstein B. "Wnt signaling during Caenorhabditis elegans embryonic development." Methods Mol Biol. 2008;469:103-111. Abstract
Rinn JL, Wang JK, Allen N, et al. "A dermal HOX transcriptional program regulates site-specific epidermal fate." Genes Dev. 2008;22:303-307. Abstract
Chen W-S, Antic D, Matis M, et al. "Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling." Cell. 2008;133:1093-1105. Abstract
Leucht P, Minear S, ten Berge D, Nusse R, Helms JA. "Translating insights from development into regenerative medicine: the function of Wnts in bone biology." Semin Cell Dev Biol. 2008;19:434-443. Abstract
2009
Wright TM, Brannon AR, Gordan JD, et al. "Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma." Oncogene. 2009;28:2513-2523. Abstract
Park J-I, Venteicher AS, Hong JY, et al. "Telomerase modulates Wnt signalling by association with target gene chromatin." Nature. 2009;460:66-72. Abstract
Mikels A, Minami Y, Nusse R. "Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling." J Biol Chem. 2009;284:30167-30176. Abstract
2010
Minear S, Leucht P, Jiang J, et al. "Wnt proteins promote bone regeneration." Sci Transl Med. 2010;2:29ra30. Abstract
2011
ten Berge D, Kurek D, Blauwkamp T, et al. "Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells." Nature cell biology. 2011;13(9):1070-5. Abstract
2012
McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. "A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration." PloS one. 2012;6(11):e26993. Abstract
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. "Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(2):370-7. Abstract
Edris B, Espinosa I, Mühlenberg T, et al. "ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour." The Journal of pathology. 2012;227(2):223-33. Abstract
van Amerongen R, Fuerer C, Mizutani M, Nusse R. "Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development." Developmental biology. 2012;369(1):101-14. Abstract
2013
Sugiyama T, Benitez CM, Ghodasara A, et al. "Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(31):12691-6. Abstract
Habib SJ, Chen BC, Tsai FC, et al. "A localized Wnt signal orients asymmetric stem cell division in vitro." Science (New York, N.Y.). 2013;339(6126):1445-8. Abstract
2014
Rinkevich Y, Montoro DT, Contreras-Trujillo H, et al. "In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration." Cell reports. 2014;7(4):1270-83. Abstract
2016
Mizutani M, Wu JC, Nusse R. "Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition." Journal of the American Heart Association. 2016;5(3):e002457. Abstract
2017
Sigal M, Logan CY, Kapalczynska M, et al. "Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis." Nature. 2017;548(7668):451-455. Abstract
Lippert A, Janeczek AA, Fürstenberg A, et al. "Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes." Biophysical journal. 2017;113(12):2762-2767. Abstract
2018
Wan DC, Morgan SL, Spencley AL, et al. "Honey bee Royalactin unlocks conserved pluripotency pathway in mammals." Nature communications. 2018;9(1):5078. Abstract
2019
Mirabelli CK, Nusse R, Tuveson DA, Williams BO. "Perspectives on the role of Wnt biology in cancer." Science signaling. 2019;12(589). Abstract