Publications

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Journal Article
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
Janssen JW, Steenvoorden AC, Collard JG, Nusse R. "Oncogene activation in human myeloid leukemia." Cancer Res. 1985;45:3262-3267. Abstract
Ardehali R, Ali SR, Inlay MA, et al. "Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(9):3405-10. Abstract
Wright TM, Brannon AR, Gordan JD, et al. "Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma." Oncogene. 2009;28:2513-2523. Abstract
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. "Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(2):370-7. Abstract
Clevers H, Loh KM, Nusse R. "Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control." Science (New York, N.Y.). 2014;346(6205):1248012. Abstract
Chu ML, Ahn VE, Choi HJ, Daniels DL, Nusse R, Weis WI. "structural Studies of Wnts and identification of an LRP6 binding site." Structure (London, England : 1993). 2013;21(7):1235-42. Abstract
Park J-I, Venteicher AS, Hong JY, et al. "Telomerase modulates Wnt signalling by association with target gene chromatin." Nature. 2009;460:66-72. Abstract
Jan TA, Chai R, Sayyid ZN, et al. "Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells." Development (Cambridge, England). 2013;140(6):1196-206. Abstract
Cadigan KM, Jou AD, Nusse R. "Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless." Development. 2002;129:3393-3402. Abstract
Cadigan KM, Fish MP, Rulifson EJ, Nusse R. "Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing." Cell. 1998;93:767-777. Abstract
Cadigan KM, Nusse R. "wingless signaling in the Drosophila eye and embryonic epidermis." Development. 1996;122:2801-2812. Abstract
Cadigan KM, Nusse R. "Wnt meeting 1996." Biochim Biophys Acta. 1997;1332:R1-5.
Rim EY, Clevers H, Nusse R. "The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators." Annual review of biochemistry. 2022;91:571-598. Abstract
Nusse R, Fuerer C, Ching W, et al. "Wnt signaling and stem cell control." Cold Spring Harb Symp Quant Biol. 2008;73:59-66. Abstract
Chai R, Kuo B, Wang T, et al. "Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(21):8167-72. Abstract
Brugmann SA, Goodnough HL, Gregorieff A, et al. "Wnt signaling mediates regional specification in the vertebrate face." Development. 2007;134:3283-3295. Abstract
Rulifson IC, Karnik SK, Heiser PW, et al. "Wnt signaling regulates pancreatic beta cell proliferation." Proc Natl Acad Sci U S A. 2007;104:6247-6252. Abstract
Cadigan KM, Nusse R. "Wnt signaling: a common theme in animal development." Genes Dev. 1997;11:3286-3305.
Kalani YMS, Cheshier SH, Cord BJ, et al. "Wnt-mediated self-renewal of neural stem/progenitor cells." Proc Natl Acad Sci U S A. 2008;105:16970-16975. Abstract
Clevers H, Nusse R. "Wnt/β-catenin signaling and disease." Cell. 2012;149(6):1192-205. Abstract
Nusse R, Clevers H. "Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities." Cell. 2017;169(6):985-999. Abstract
Lee SH, Johnson DT, Luong R, et al. "Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration." Stem cells (Dayton, Ohio). 2015;33(11):3356-67. Abstract
Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R. "Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation." Proceedings of the National Academy of Sciences of the United States of America. 2014;111(49):E5262-71. Abstract
Basham KJ, Rodriguez S, Turcu AF, et al. "A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis." Genes & development. 2019;33(3-4):209-220. Abstract