Wnt/β-catenin signaling and disease.
Submitted by Anonymous on Wed, 10/10/2012 - 11:40
| Title | Wnt/β-catenin signaling and disease. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Clevers H, Nusse R |
| Journal | Cell |
| Volume | 149 |
| Issue | 6 |
| Pagination | 1192-205 |
| Date Published | 2012 Jun 8 |
| ISSN | 0092-8674 |
| Abstract | The WNT signal transduction cascade controls myriad biological phenomena throughout development and adult life of all animals. In parallel, aberrant Wnt signaling underlies a wide range of pathologies in humans. In this Review, we provide an update of the core Wnt/β-catenin signaling pathway, discuss how its various components contribute to disease, and pose outstanding questions to be addressed in the future. |
| URL | http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(12)00586-7 |
| DOI | 10.1016/j.cell.2012.05.012 |
| Short Title | Cell |
