Zeng L, Liu Y, Nguyenla XH, Abbott TR, Han M, Zhu Y, Chemparathy A, Lin X, Chen X, Wang H, Rane DA, Spatz JM, Jain S, Rustagi A, Pinsky B, Zepeda AE, Kadina AP, Walker JA 3rd, Holden K, Temperton N, Cochran JR, Barron AE, Connolly MD, Blish CA, Lewis DB, Stanley SA, La Russa MF, Qi LS, “Broad - spectrum CRISPR - mediated inhibition of SARS - CoV - 2 va riants and endemic coronaviruses in vitro,” Nature Communications 2022, May 19;13(1):2766. doi: 10.1038/s41467 - 022 - 30546 - 7. pdf reprint
Benjamin AB, Moule MG, Didwania MK, Hardy J, Saenkham - Huntsinger P, Sule P, Nielsen JE, Lin JS, Contag CH, Barron AE, Cirillo JD, “Efficacy of Cathelicidin - Mimetic Antimicrobial Peptoids against Staphylococcus aureus,” Microbiology Spectrum 2022, Apr 25:e0053422. doi: 10.1128/spectrum.00534 - 22. Epub ahead of print. pdf reprint
Nielsen JE, Alford MA, Yung D BY, Molchanova N, Fortkort JA, Lin JS, Diamond G, Hancock REW, Jenssen H, Pletzer D, Lund R, Barron AE, “Self - Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens,” ACS Infectious Diseases 2022, 11, 533 - 545. doi : 10.1021/acsinfecdis.1c00536. Epub 2022. pdf reprint
Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE , ” Potent Antiviral Activit y against HSV - 1 and SARS - CoV - 2 by Antimicrobial Peptoids ,” Pharmaceuticals (Basel) 2021 , Mar 31;14(4):304. doi: 10.3390/ph14040304. pdf reprint
Molchanova N, Nielsen JE, Sørensen KB, Prabhala BK, Hansen PR, Lund R, Barron AE, Jenssen H , “H alogenation as a tool to tune antimicrobial activity of peptoids ,” Sci entific Reports 2020 , Sep 9;10(1):14805. doi: 10.1038/s41598 - 020 - 71771 - 8. pdf reprint
Brown NJ, Lin JS, Barron AE, "Helical side chain chemistry of a peptoid-based SP-C analogue: Balancing structural rigidity and biomimicry," Biopolymers 2019 Apr 10:e23277. pdf reprint
Lee J, Kang D, Choi J, Huang W, Wadmanc M, Barron AE, Seo J, "Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids," Bioorganic & Medicinal Chemistry Letters 28 (2018) 170–173. pdf reprint
Mooney JA, Pridgen EM, Manasherob R, Suh G, Blackwell HE, Barron AE, Bollyky PL, Goodman SB, Amanatullah DF, “Implant-associated bacterial biofilm and quorum sensing in periprosthetic joint infections,” Journal of Orthopaedic Research 2018. pdf reprint
Czyzewski AM, McCaig LM, Dohm MT, Broering LA, Yao L, Brown NJ, Didwania MK, Lin JS, Lewis JF, Veldhuizen R, Barron AE,“Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins,” Scientific Reports 2018, 8, 6795. pdf reprint
Chongsiriwatana NP, Lin JS, Kapoor R, Wetzler M, Rea JAC, Didwania MK, Contag CH, Barron AE, “Intracellular biomass flocculation as a key mechanism of rapid bacterial killing by cationic, amphipathic antimicrobial peptides and peptoids,” Scientific Reports 2017, 7, 16718. pdf reprint
Czyzewski AM, Jenssen H, Fjell CD, Waldbrook M, Chongsiriwatana NP, Yuen E, Hancock RE, Barron AE, “In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents,” PLOS ONE 2016, 11, 1-17. pdf reprint
Lee J, Huang W, Broering JM, Barron AE, Seo J, “Prostate tumor specific peptide-peptoid hybrid prodrugs,” Bioorganic & Medicinal Chemistry Letters 2015, 25: 2849-2852. pdf reprint
Huang W, Seo J, Willingham SB, Czyzewski AM, Gonzalgo ML, Weissman IL, Barron AE, “Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity,” PLOS ONE 2014; 9 (2). pdf reprint
Park M, Wetzler M, Jardetzky TS, Barron AE, “A Readily Applicable Strategy to Convert Peptides to Peptoid-based Therapeutics,” PLOS ONE 2013; 8 (3). pdf reprint
Huang W, Seo J, Lin JS, Barron AE, “Peptoid transporters: effects of cationic, amphipathic structure on their cellular uptake,” Molecular Biosystems 2012, 8, 2626-2628.pdf reprint
Seo J, Ren G, Liu H, Miao Z, Park M, Wang Y, Miller TM, Barron AE, Cheng Z, “In Vivo Biodistribution and Small Animal PET of (64)Cu-Labeled Antimicrobial Peptoids,” Bioconjugate Chemistry 2012, 23, 1069-1079. pdf reprint
McDermott G1, Fox DM, Epperly L, Wetzler M, Barron AE, Le Gros MA, Larabell CA, “Visualizing and quantifying cell phenotype using soft X-ray tomography”, Bioessays 2012, 34, 320-327.pdf reprint
Chongsiriwatana NP, Wetzler M, Barron AE, “Functional Synergy between Antimicrobial Peptoids and Peptides against Gram-Negative Bacteria,” Antimicrob Agents Chemother. 2011, 55, 5399-5402. pdf reprint
Brown NJ, Dohm MT, Bernardino de la Serna J, Barron AE, “Biomimetic N-terminal alkylation of peptoid analogues of surfactant protein C,” Biophys J. 2011, 101, 1076-85. pdf reprint
Dohm MT, Kapoor R, Barron AE, “Peptoids: Bio-Inspired Polymers as Potential Pharmaceuticals,” Curr Pharm Des. 2011. pdf reprint
Kapoor R, Wadman MW, Dohm MT, Czyzewski AM, Spormann AM, Barron AE, “Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms,” Antimicrob. Agents Chemother. 2011, 55, 3054-3057. pdf reprint
Kapoor R, Eimerman PR, Hardy JW, Cirillo JD, Contag CH, Barron AE, "Efficacy of antimicrobial peptoids Against Mycobacterium," Antimicrob. Agents Chemother. 2011, 55, 3058-3062. pdf reprint
Park M, Matsuura H, Lamb RA, Barron AE, Jardetzky TS, “A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform,” Analytical Biochemistry 2011, 409, 195-201. pdf reprint
Chongsiriwatana NP, Miller TM, Wetzler M, Vakulenko S, Karlsson AJ, Palecek SP, Mobashery S, Barron AE, “Short alkylated peptoid mimics of antimicrobial lipopeptides,” Antimicrobial Agents and Chemotherapy 2011, 55, 417-420. pdf reprint
Dohm MT, Brown NJ, Seurynck-Servoss SL, de la Serna JB, Barron AE, “Mimicking SP-C palmitoylation on a peptoid-based SP-B analogue markedly improves surface activity,” Biochimica Et Biophysica Acta Biomembranes 2010, 1798, 1663-1678. pdf reprint
Dohn MT, Mowery BP, Czyzewski AM, Stahl SS, Gellman SH, Barron AE, “Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers,” Journal of the American Chemical Society 2010, 132, 7957-7967. pdf reprint
Chongsiriwatana NP, Barron AE, “Comparing bacterial membrane interactions of antimicrobial peptides and their mimics,” Methods Mol Biol. 2010; 618:171-82. pdf reprint
Uchida M, McDermott G, Wetzler M, Le Gros MA, Myllysa M, Knoechel C, Barron AE, Larabell CA, “Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicans,” PNAS, 2009, 46, 19375–19380. pdf reprint
Seo J, Michaelian N, Owens SC, Dashner ST, Wong AJ, Barron AB, Carrasco MR, “Chemoselective and microwave-assisted synthesis of gycopeptoids,” Organic Letters, 2009, 22, 5210-5213. pdf reprint
Dohm MT, Seurynck-Servoss SL, Seo J, Zuckermann RN, Barron AE, "Close mimicry of lung surfactant protein B by "clicked" dimers of helical, cationic polypeptoids," PeptideScience 2009, 6, 538-553. pdf reprint
Chongsiriwatana NP, Patch JA, Czyzewski AM, Dohm MT, Ivankin A, Gidalevitz D, Zuckermann RN, Barron AE, "Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides," PNAS 2008, 105: 2794-2799. pdf reprint
Brown NJ, Wu CW, Seurynck-Servoss SL, Barron AE, "Effects of hydrophobic helix length and side chain chemistry on biomimicry in peptoid analogues of SP-C," Biochemistry 2008, 47: 1808-1818. pdf reprint
Brown NJ, Johansson J, Barron AE, "Biomimicry of surfactant protein C," Acc. Chem. Res. 2008, 41, 1409-1417. (Review article) pdf reprint
Statz AR, Park JP, Chongsiriwatana NP, Barron AE, Messersmith PB, "Surface-immobilised antimicrobial peptoids," Biofouling 2008, 24, 439-448 pdf reprint
Czyzewski AM, Barron AE, "Protein and Peptide Biomimicry: Gold Mining Inspiration from Nature's Ingenuity," AIChE Journal 2008, 54: 1-7. pdf reprint
Seurynck-Servoss SL, Brown NJ, Dohm MT, Wu CW, Barron AE, "Lipid composition greatly affects the in vitro surface activity of lung surfactant protein mimics," Colloids & Surfaces B: Biointerfaces 2007, 57: 37-55. pdf reprint
Seurynck-Servoss SL, Dohm MT, Barron AE, "Effects of including an N-terminal insertion region and arginine-mimetic side chains in helical peptoid analogues of lung surfactant protein B", Biochemistry, 2006, 45: 11809-11818. pdf reprint
Huang K, Wu CW, Sanborn TJ, Patch JA, Kirshenbaum K, Zuckermann RN, Barron AE, Radhakrishnan I, "A threaded loop conformation adopted by a family of peptoid nonamers," Journal of the American Chemical Society 2006, 128: 1733-1738. pdf reprint
Seurynck SL, Brown NJ, Wu CW, Germino KW, Kolmeir EK, Ingenito EP, Glucksberg MR, Barron AE, Johnson M, "Optical monitoring of bubble shape and size in a pulsating bubble surfactometer," Journal of Applied Physiology 2005, 99: 624-633. pdf reprint
Seurynck SL, Patch JA, Barron AE, "Simple, helical peptoid analogs of lung surfactant protein B," Chemistry and Biology 2004, 12: 77-88. pdf reprint
Patch JA, Kirshenbaum K, Seurynck SL, Zuckermann RN, Barron AE, "Versatile Oligo (N-substituted) Glycines: The Many Roles of Peptoids in Drug Discovery," Pseudo-peptides in Drug Discovery, P.E. Nielsen, ed., (2004) John Wiley & Sons Publishers, Hoboken, NJ. (book chapter) pdf reprint
Patch JA, Barron AE, "Helical peptoid mimics of magainin-2 amide," Journal of the American Chemical Society 2003, 125: 12092-12093. pdf reprint
Wu CW, Kirshenbaum K, Sanborn TJ, Patch JA, Huang K, Dill KA, Zuckermann RN, Barron AE, "Structural and spectroscopic studies of peptoid oligomers with a-chiral, aliphatic side chains," Journal of the American Chemical Society 2003, 125: 13525-13530. pdf reprint
Wu CW, Seurynck SL, Lee KYC, Barron AE, "Helical peptoid mimics of lung surfactant protein C," Chemistry & Biology 2003, 10: 1057-1063. pdf reprint
Patch JA, Barron AE, "Mimicry of bioactive peptides via non-natural, sequence-specific peptidomimetic oligomers," Current Opinion in Chemical Biology 2002, 6: 872-877. pdf reprint
Sanborn TJ, Wu CW, Zuckermann RN, Barron AE, "Extreme stability of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with a-chiral side chains," Biopolymers 2002, 63: 12-20. pdf reprint
C.W. Wu and A.E. Barron, "Biomimetic Lung Surfactant Replacements," in Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering and Targeted Drug Delivery, A.K. Dillow and A. Lowman, Eds. (2002) Marcel-Dekker Publishers, New York. (book chapter) pdf reprint
Wu CW, Sanborn TJ, Huang K, Zuckermann RN, Barron AE, "Peptoid oligomers with a-chiral, aromatic side chains: sequence requirements for the formation of stable peptoid helices," J. Am. Chem. Soc. 2001, 123: 6778-6784. pdf reprint
Wu CW, Sanborn TJ, Zuckermann RN, Barron AE, "Peptoid oligomers with a-chiral, aromatic side chains: effects of chain length on secondary structure," J. Am. Chem. Soc. 2001, 123: 2958-2963. pdf reprint
Barron AE and Zuckermann RN, "Bioinspired polymeric materials: In-between proteins and plastics," Current Opinion in Chemical Biology 1999, 3: 681-687. pdf reprint
Armand P, Kirshenbaum K, Goldsmith RE, Farr-Jones S, Barron AE, Truong KTV, Dill KA, Zuckermann RN, "NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains," Proc. Natl. Acad. Sci. USA 1998, 95: 4309-4314. pdf reprint
Kirshenbaum K, Barron AE, Goldsmith RE, Armand P, Bradley EK, Truong KTV, Dill KA, Cohen FE, Zuckermann RN, "Sequence-specific polypeptoids: A diverse family of heteropolymers with stable secondary structure," Proc. Natl. Acad. Sci. USA 1998, 95: 4303-4308. pdf reprint