[1975-1979] [1980-1989] [1990-1995] [1996-current]

Park, H., Davis, R. E., and Wang, T.S.-F. Studies of Schizosaccharomyces pombe DNA polymerase a during the cell cycle. Nucleic Acids Res. 23: 4337-4344. 1995

Wang, T. S.-F., Copeland, W. C., Rogge, L., and Dong, Q. Purification of mammalian DNA polymerase a. In: Methods in Enzymology. Edited by J. L. Campbell. Vol. 262. 77-84. 1995.

Copeland, W. C., Dong, Q., and Wang, T. S.-F. Rationale for mutagenesis of DNA polymerase active sites: DNA polymerase a. In: Methods in Enzymology. Edited by J. L. Campbell. Vol 262. 294-303. 1995.

Lee, S. K., Dong, Q., Wang, T. S.-F. , and Lehman, I. R. Interaction of herpes simplex virus type I origin binding protein with DNA polymerase a. Proc. Natl. Acad. Sci. USA. 92: 7882-7886. 1995.

Dong, Q. and Wang, T. S.-F. Mutational studies of human DNA polymerase a: Lysine950 in the third most conserved region of a-like DNA polymerases is involved in binding the deoxynucleoside triphosphate. J. Biol. Chem. 270: 21563-21570. 1995.

Park, P., Copeland, W. C., Yang, L., Wang, T. S.-F., Botchan, M., and Mohr, I.. The cellular DNA polymerase a-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc. Natl. Acad. Sci. USA. 91: 8700-8704. 1994.

Dong, Q., Copeland, W. C. and Wang, T.S.-F. Mutational studies of human DNA polymerase a. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis. J. Biol. Chem. 268: 24163-24174. 1993.

Dong, Q., Copeland, W. C. and Wang, T.S.-F. Mutational studies of human DNA polymerase a. Serine867 in the second most conserved region among a-like DNA polymerases is involved in primer binding and mispair-primer extension. J. Biol. Chem. 268: 24175-24182. 1993.

Francesconi, S. , Park, H. and Wang, T.S.-F. Fission yeast DNA polymerase d temperature-sensitive alleles exhibit cell division cycle phenotype. Nucleic Acid Res. 21: 3821-3828. 1993.

Francesconi, S., Copeland, W.C. and Wang, T.S.-F. In vivo species specificity of DNA polymerase a. Mol. Gen. Genet. 241: 457-466. 1993.

Copeland, W.C. and Wang, T.S.-F. Mutational analysis of human DNA polymerase a: The most conserved region among a-like DNA polymerases is involved in metal specific catalysis. J. Biol. Chem. 268: 11028-11040. 1993.

Copeland, W.C., Lam, N. K., and Wang, T.S.-F. Fidelity studies of human DNA polymerase a: The most conserved region among a-like DNA polymerases is responsible for metal induced infidelity in DNA synthesis. J. Biol. Chem. 268: 11041-11049. 1993.

Park, H., Francesconi, S., and Wang, T. S.-F. Cell cycle expression of two replicative DNA polymerases a and d from Schizosaccharomyces pombe. Mol. Biol. Cell. 4: 145-157. 1993.

Chen, M.S., Suttmann, R.T., Papp, E., Bach, C., McRoberts, M.J., Copeland, W.C. and Wang T.S.-F. Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodifficient virus type I and human DNA polymerases a and b. Biochemistry 32: 6002-6010. 1993.

Dornreiter, I., Copeland, W.C. and Wang, T.S.-F. Initiation of SV40 DNA replication requires the interaction of a specific domain of human DNA polymerase a with large T antigen. Mol. Cell. Biol. 13: 809-820. 1993

Copeland, W.C., Chen, M.S. and Wang, T.S.-F. Human DNA polymerases a and b are able to incorporate anti-HIV deoxynucleotide into DNA. J. Biol. Chem. 267: 21459-21464. 1992.

Rogge, L. and Wang, T. S.-F. Protein affinity chromatography reveals cell cycle dependent association of cellular factors with human DNA polymerase a. Chromosoma 102: 114-120, 1992

Copeland, W.C. and Wang, T.S.-F. Catalytic subunit of human DNA polymerase a overproduced from baculovirus-infected insect cells: Structural and enzymological characterization. J. Biol. Chem. 266: 22739-22748. 1991.

Pearson, B.E., Nasheuer, H-P. and Wang, T.S.-F. Human DNA polymerase a gene: Sequences controlling expression in cycling and serum stimulated cells. Mol. Cell. Biol. 11: 2081-2095, 1991.

Nasheuer, H-P., Moore, A.L., Wahl, A.F. and Wang, T.S.-F. Cell cycle-dependent phosphorylation of human DNA polymerase a. J. Biol. Chem. 266: 7893-7903. 1991.

Adler, D.A., Tseng, B.Y., Wang, T.S.-F. and Disteche, C.M. Physical mapping of the genes for three components of the mouse DNA replication complex: Polymerase a to the X chromosome, primase p49 subunit to chromosome 10, and primase p58 subunit to chromosome 1. Genomic 9: 642-646.1991.

Hsi, K.-L., Copeland, W.C. and Wang, T.S.-F. Human DNA polymerase a catalytic polypeptide binds ConA and RCA and contains a specific labile site in the N-terminus. Nucleic Acids Res. 18: 6231-6237. 1990.

Wang, T.S.-F.. Human DNA polymerase a: A retrospective and prospective. In: The Eukaryotic Nucleus: Molecular Structure and Macromolecular Assemblies. 147-198. Edited by Strauss, P. and Wilson, S., Telford Press. 1990.

Last updated: November 12, 1999

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