Co-Principal Investigators: Dennis R. Carter, PhD and Gary S.Beaupré, PhD Collaborator: Stuart Goodman and David Schurman, MD Project Category: Arthritis - 2000 Description: To understand how bones change following joint replacement surgery, simulated loads are applied to a computer model of the femur. The model calculates the effects over time and shows which areas of the femur lose bone and which areas gain bone. These models reflect the patterns of change thatoccur in natural bones. The computer models are compared with both experimental, radiographic, and clinical results. Problem: Bone loss with aging andbone loss after total joint replacement can leave a bone weakened and susceptible to fracture. This bone loss is caused by changes in activity level and by changes in the way mechanical loads are transmitted throughout the skeleton. Approach: Through engineering analysis we are better able to understand the role played by mechanical loads in the maintenance of healthy bones and joints. These models aid in the design of artificial implants that work more like the natural bones and joints they replace. Related work: Mechanical loads are also necessary for maintaining healthy cartilage in our joints. Dr. Lane Smith is investigating how one type of mechanical load is beneficial to joint cartilage, while another type can lead to degeneration and arthritic changes. Updated 02/02/2001 |
