Publications

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2020
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
2019
Basham KJ, Rodriguez S, Turcu AF, et al. "A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis." Genes & development. 2019;33(3-4):209-220. Abstract
2014
Rinkevich Y, Montoro DT, Contreras-Trujillo H, et al. "In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration." Cell reports. 2014;7(4):1270-83. Abstract
2012
Nusse R, Varmus H. "Three decades of Wnts: a personal perspective on how a scientific field developed." The EMBO journal. 2012;31(12):2670-84. Abstract
2009
Park J-I, Venteicher AS, Hong JY, et al. "Telomerase modulates Wnt signalling by association with target gene chromatin." Nature. 2009;460:66-72. Abstract
2008
Kalani YMS, Cheshier SH, Cord BJ, et al. "Wnt-mediated self-renewal of neural stem/progenitor cells." Proc Natl Acad Sci U S A. 2008;105:16970-16975. Abstract
2004
Johnson ML, Harnish K, Nusse R, Van Hul W. "LRP5 and Wnt signaling: a union made for bone." J Bone Miner Res. 2004;19:1749-1757.
Verras M, Brown J, Li X, Nusse R, Sun Z. "Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells." Cancer Res. 2004;64:8860-8866. Abstract
2001
Roberts RJ, Varmus HE, Ashburner M, et al. "Information access. Building a "GenBank" of the published literature." Science. 2001;291:2318-2319.
1997
Von Ohlen T, Lessing D, Nusse R, Hooper JE. "Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein." Proc Natl Acad Sci U S A. 1997;94:2404-2409. Abstract
Willert K, Brink M, Wodarz A, Varmus H, Nusse R. "Casein kinase 2 associates with and phosphorylates dishevelled." EMBO J. 1997;16:3089-3096. Abstract
1992
Nusse R, Varmus HE. "Wnt genes." Cell. 1992;69:1073-1087.
1991
Nusse R, Brown A, Papkoff J, et al. "A new nomenclature for int-1 and related genes: the Wnt gene family." Cell. 1991;64:231.
Van de Vijver MJ, Nusse R. "The molecular biology of breast cancer." Biochim Biophys Acta. 1991;1072:33-50.
1990
Schuuring E, van der Leede BJ, Willems R, et al. "Differentiation-dependent expression of provirus-activated int-1 oncogene in clonal cell lines derived from a mouse mammary tumor." Oncogene. 1990;5:459-465. Abstract
van Leeuwen F, Van de Vijver MJ, Lomans J, et al. "Mutation of the human neu protein facilitates down-modulation by monoclonal antibodies." Oncogene. 1990;5:497-503. Abstract
1988
Van de Vijver MJ, Peterse JL, Mooi WJ, et al. "Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer." N Engl J Med. 1988;319:1239-1245. Abstract
Van de Vijver MJ, Mooi WJ, Wisman P, Peterse JL, Nusse R. "Immunohistochemical detection of the neu protein in tissue sections of human breast tumors with amplified neu DNA." Oncogene. 1988;2:175-178. Abstract
Van de Vijver MJ, Mooi WJ, Peterse JL, Nusse R. "Amplification and over-expression of the neu oncogene in human breast carcinomas." Eur J Surg Oncol. 1988;14:111-114. Abstract
1987
van de Vijver M, van de Bersselaar R, Devilee P, Cornelisse C, Peterse J, Nusse R. "Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene." Mol Cell Biol. 1987;7:2019-2023. Abstract
1985
Nusse R, van Ooyen A, Rijsewijk F, van Lohuizen M, Schuuring E, van't Veer L. "Retroviral insertional mutagenesis in murine mammary cancer." Proc R Soc Lond B Biol Sci. 1985;226:3-13. Abstract
1984
Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. "Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15." Nature. 1984;307:131-136. Abstract
1982
Nusse R, Varmus HE. "Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome." Cell. 1982;31:99-109. Abstract
1980
Nusse R, Janssen H, de Vries L, Michalides R. "Analysis of secondary modifications of mouse mammary tumor virus proteins by two-dimensional gel electrophoresis." J Virol. 1980;35:340-348. Abstract
1975
Van Blitterswijk WJ, Emmelot P, Hilgers J, Kamlag D, Nusse R, Feltkamp CA. "Quantitation of virus-induced (MLr) and normal (Thy.1.2) cell surface antigens in isolated plasma membranes and the extracellular ascites fluid of mouse leukemia cells." Cancer Res. 1975;35:2743-2751. Abstract