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Single-molecule
studies of RNA polymerase: motoring along.
Herbert, Greenleaf, Block. Annual
Review of Biochemistry (2008). |
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Applied
Force Reveals Mechanisticand Energetic Details
of Transcription Termination. Larson, Greenleaf,
Landick, Block. Cell (2008). Click here
for Cell
Commentary. |
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Direct
Observation of Hierarchical Folding in Single
Riboswitch Aptamers. Greenleaf, Frieda,
Foster, Woodside, Block. Science (2008). |
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Precision
steering of an optical trap by electro-optic
deflection. Valentine, Guydosh, Gutiérrez-Medina,
Fehr, Andreasson, Block. Optics Letters
(2008). |
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Kinesin
Steps Do Not Alternate in Size. Fehr, Asbury,
Block. Biophysical Journal: Biophysical
Letters (2007). |
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Binding, Stepping, Tracking, Gating,
and Limping. Block. Biophysical Journal
(2007). |
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Not
So Lame After All: Kinesin Still Walks with
a Hobbled Head. Guydosh, Block. JGP (2007). |
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Molecule
by molecule, the physics and chemistry of
life: SMB2007. Block, Larson, Greenleaf,
Herbert, Guydosh, Anthony. Nature Chemical
Biology (2007). |
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High-Resolution,
Single-Molecule Measurements of Biomolecular
Motion. Greenleaf, Woodside, Block. Annual
Review of Biophysics Biomolecular Structure
(2007). |
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Eg5
steps it up! Valentine, Fordyce, and Block.
Cell Division (2006). |
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Direct
measurement of the full, sequence-dependent
folding landscape of a nucleic acid. Woodside,
Anthony, Behnke-Parks, Larizadeh, Herschlag,
and Block. Science (2006). Click here
for
Supplemental Materials. |
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Single-molecule,
motion-based DNA sequencing using RNA polymerase.
Greenleaf and Block. Science (2006).
Click here for
Supplemental Materials. |
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Pulling
on the nascent RNA during transcription
does not alter kinetics of elongation or
ubiquitous pausing. Dalal, Larson, Neuman,
Gelles, Landick, and Block. Molecular Cell
(2006). Click here for Supplemental
Materials. |
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Sequence-resolved
detection of pausing by single RNA polymerase
molecules. Herbert, La Porta, Wong, Mooney,
Neuman, Landick and Block. Cell (2006).
Click here for Supplemental
Materials. Click here for Cell
Commentary. Click here for the Stanford
Report article. |
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Backsteps
induced by nucelotide analogs suggest the
front head of kinesin is gated by strain.
Guydosh and Block. PNAS (2006). Click
here for Supplemental
Materials. |
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Nanomechanical
measurements of the sequence-dependent folding
landscapes of single nucleic acid hairpins.
Woodside, Behnke-Parks, Larizadeh, Travers,
Herschlag, and Block. PNAS (2006). Click
here for Supplemental
Materials. |
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Individual
dimers of the mitotic kinesin motor Eg5
step processively and support substantial
loads in vitro. Valentine, Fordyce,
Krzysiak, Gilbert and Block. Nature Cell
Biology (2006). Click here for Supplemental
Materials. |
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