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Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II. Larson, Zhou, Kaplan, Palangat, Kornberg, Landick and Block. PNAS (2012). Click here for Supplemental Materials. |
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Electrostatics of nucleic acid folding under conformational constraint. Anthony, Sim, Chu, Doniach, Block and Herschlag. JACS (2012). Click here for Supplemental Materials. |
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Folding energy landscape of the thiamine pyrophosphate riboswitch aptamer. Anthony, Perez, García-García and Block. PNAS (2012). Click here for Supplemental Materials. |
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Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA. Zhou, Ha, La Porta, Landick and Block. Molecular Cell (2011). |
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Optical tweezers study life under tension. Fazal and Block. Nature Photonics (2011). |
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A universal pathway for kinesin stepping. Clancy,
Behnke-Parks, Andreasson, Rosenfeld and Block. Nature Structural & Molecular Biology (2011).Click here for Supplemental
Materials. |
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Single-molecule
studies of RNA polymerase: one singular
sensation, every little step it takes. Larson,
Landick, and Block. Molecular Cell (2011). |
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Visualizing individual microtubules using bright-field microscopy. Gutiérrez-Medina and Block. American Journal of Physics (2010). |
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An
optical apparatus for rotation and trapping.
Gutiérrez-Medina, Andreasson, Greenleaf,
La Porta, and Block. Methods in Enzymology
(2010). |
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E.
coli NusG inhibits backtracking and accelerates
pause-free transcription by promoting forward
translocation of RNA polymerase. Herbert,
Zhou, Mooney, La Porta, Landick, and Block.
Journal of Molecular Biology (2010). |
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