A Novel Approach for the Structural Determination of Oligomeric Complexes By in-silico Prediction Methods and Mass Spectrometry: Application to the chaperonin TRiC.
Judith Frydman (Biology)
Michael Levitt (Structural Biology)

Our overall goal combines experimental and computational approaches in the tightly integrated manner needed obtain high-resolution structural information by combining mass spectrometry (MS) combined with cross-linking chemistry [Borch, 2005; Sinz, 2006].