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Stephen Lee
Bio-X Bioengineering Graduate Fellow 2005
Graduated 2008
Professor Jennifer Cochran (Bioengineering)
The Cochran lab uses directed evolution and yeast display to create novel protein mutants for therapeutics in wound healing and cancer applications. Stephen’s current project investigates mutants of human epidermal growth factor (EGF), a protein involved in both of these pathways. In vitro assays are being used to study the migratory and proliferative effects of EGF on murine and human fibroblasts. His goal is to demonstrate an EGF mutant with improved migration and proliferation over wildtype to ultimately test in mice in vivo.
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