Course Outline

Overview

The course covers the basic principles of NMR relaxation theory as it applies in vivo, followed by detailed discussions of contrast mechanisms exploited in MRI applications.

This Outline may be updated during the course.
More details can be found at the Schedule link.

Outline

Section A: Review of NMR Spin Physics

• NMR Spin Operators

• The Nuclear Spin Hamiltonian

Section B: Introduction to NMR Relaxation

• Basics Principles of In vivo NMR Relaxation

• Dipolar Coupling

• Chemical Exchange

• In Vivo Water

Section C: Redfield Relaxation Theory

• Perturbation Theory and the Master Equation of NMR

• Dipolar Coupling Revisited

• Redfield Theory Examples

• Relaxation in the rotating frame

Section D: MRI Contrast Agents

• Paramagnetic Relaxation Enhancement

• T2, T2*, and PARACEST Contrast Agents

Section E: Applications

• MRI of Blood

• Cartilage Imaging

• Dynamic Nuclear Polarization

Important Dates

See Schedule

No class the week of May 13-17 due to ISMRM Conference
Final Presentations, Date & Location TBA