knockout By Ivan Suarez Robles 10 Nov, 2010 Refers to an organism that has a particular gene or trait purposely removed by selective breeding or laboratory techniques (e.g., a huntingtin knockout mouse).Related Articles: Dr. Elena CattaneoMice in HD Research"Normal" huntingtin and Huntington's disease Adipose Derived Stem Cells and HD: Real Applications of iPSCsGenome Editing