Paula Petrone`s Web Page

                

 

 

* Current Projects

* Publications

* Contact Information

* Biographical Information / CV

    * Favorite Links

 

 

AppleMark

 

 

 

 

 

 

 

 

 

 

 

 

 


Current Projects

 

I work in Vijay Pande `s Lab at Stanford, doing research in Computer Simulations of Large Biomolecules.

This is my second year in the Stanford Biophysics PhD Program.

I am interested in coarse grain dynamics of large biomolecules, and trying to understand the collective motions of atoms that could be relevant for biological function.

 

 


 

 

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Publications

 

Metal-Insulator transition in the double perovskites.

A.A. Aligia, P. Petrone. Phys. Rev. B, 64, 092414, 2001.

 

Effective three-band model for double perovskites.  P. Petrone, A. A. Aligia, Phys. Rev. B 66, 104418, 2002.

 

MHC-Peptide Binding is Assisted by Bound Water Molecules, Paula M. Petrone and Angel E. Garcia. Journal of Molecular Biology,  Volume 338, Issue 2, 23 April 2004,  Pages 419-435.

 

Can conformational change be described by only a

few normal modes? Paula Petrone, Vijay Pande, Biophysical Journal, in press 2005.

 

 

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Contact Information

E-mail address

ppetrone@stanford.edu

 

 

 Mail

 

Paula Petrone

Pande Group

Clark Center, MC 5447

Stanford University

Stanford, CA 94305-5447

 

Web address

Personal Web Page under Construction

 

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Biographical Information

 

 I was born in Buenos Aires, Argentina in 1976. 

 

 In 2001, I obtained my Undergraduate Degree (Licenciatura) in Physics at Insituto Balseiro, Argentina, which is equivalent to a Masters Degree in the US, because of its duration and the 2-year thesis required for its completion. My project was in Solid State Physics. It consisted of ab-initio and analytical calculations for an effective band model of double perovskites. My advisor was Dr. Armando Aligia.

 

 

 

 

Cerro Lopez. Bariloche 2001.

 

 

 

 

 

In 2002, I was hired as Graduate Research Assistant at the Theoretical Biology and Biophysics Division at Los Alamos National Laboratory. My mentor was Angel Garcia. We performed Molecular Dynamics Simulations to study the role of water in the binding of endogenous peptides in the MHC-receptor. This work was my first approach to Biophysics and showed me that living systems comprise an immense source of challenging (and maybe unsolvable) problems for a physicist.

 

AppleMark

                Bandelier National Park. Los Alamos 2002.

 

 

Today, I am working in Vijay Pande`s group, at Stanford, looking for new approaches to model the dynamics and structure of large biomolecules.

I am interested in conformational changes in proteins. The study of how and why proteins undergo big structural changes upon binding of ligands is relevant for drug-prediction and many other fundamental aspects of biology and biophysics.

 

 

AppleMark

AppleMark

 

Marine National Headlands.                     Big Sur Pfeiffer Beach.

San Francisco 2003.

 

My new project involves a big macromolecule: the Ribosome.

The Ribosome is the factory where aminoacids are assembled into new proteins as prescribed by  the DNA. The ribosome is crucial for the cell to exist. Little is known about the methods, chemistry and structural motions that take place in the ribosome.  I am currently investigating different approaches to treat this problem whose biological complexity is a challenge to both experimental and computational techniques.

 

Russian Ridge up Skyline. My favourite biking trail and sunset-watching spot near work.

 

 

 

One of my non-scientific projects involves the Food Shelter

Las Perlitas de Maria,  in Cordoba, Argentina.

 

http://www.lasperlitasdemaria.com/

 

This shelter hosts dozens of infants and pregnant mothers in extreme poverty and lacks any funding from the Argentine government. Together with Argentine students at Stanford, every year we collect funds to help this shelter. Even if our contribution is small, we believe that we are making a difference. If you would like to help us, be on our mailing list or have any ideas that would make our fund raising more effective, please contact me soon.

Favorite Links

 

* Pande Group: My current job

* Instituto Balseiro -CAB : My school in Argentina

* Las Perlitas de Maria: Food shelter in Cordoba, Argentina.

* My photo gallery: adventures, trips, friends & family (in construction)

* Por Los Chicos : Free online donation of food to hungry kids in Argentina.

* LaNacionLine

* NewYorkTimes

* Craig`s List: everything you can sell/buy in the bay area.

 

 

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Last revised: December 2, 2005.