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palanker@stanford.edu | |
|---|---|---|
| Phone | (650) 725-0059 | |
| Fax | (650) 725-8311 | |
| Address | Stanford University, Hansen Experimental Physics Laboratory 452 Lomita Mall, room 135 Stanford, CA 94305-4085, USA |
Professional Interests
Mechanisms of interaction of electric field and light with biological cells and tissues, and applications of these interactions to medicine and biology:
- Effects of pulsed electric field on ion channels and cellular membranes
- Electro-neural interfaces
- Laser-tissue interactions
- Plasma-mediated microsurgical technologies
- Minimally-invasive electro-optical therapeutic technologies
- Optical imaging and spectroscopy
Current research projects
- Artificial Sight - Optoelectronic Retinal Prosthesis
- Laser-Tissue Interactions – mechanisms and applications
- Electronic Control of Vasculature
- Pulsed Electron Avalanche Knife (PEAK)
Some of the previous research projects
- Coherent Anti-Stokes Raman Scattering (CARS) Microscopy
- Optical detection of physiological stress (based on light scattering spectroscopy)
- Plasma-mediated electroporation
- Pulsed liquid microjet
- Near-field Infrared Microscopy with:
- Transient optical elements (using photo-induced reflectivity)
- Tapered fibers
- Microfabricated solid-immersion lenses
- ArF excimer laser-based system for vitreoretinal surgery
- ArF excimer laser-based system for debridement of the damaged skin
- Ablation of zona pellucida in oocytes for in-vitro fertilization:
- Photolysis using the ArF excimer laser-based system
- Thermolysis using a microheater-based system
- Laser poration of cellular membrane: parallel permeabilization of millions of cells using an array of microapertures
- Statistical approach to sub-wavelength measurements using a static array of near-field apertures (This idea later inspired a revolutionary approach to rapid DNA sequencing: SMRT™ technology by Pacific Biosciences Inc.)
Teaching
- Lasers in Medicine
- Basic Science Course in Ophthalmology (lectures on Ophthalmic Lasers)
- Making Sense of the Human Senses (part related to restoration of sight through biotechnology)
Technology Transfer
- More than 20 issued patents and patent applications have been transferred to industrial development and manufacturing.
- Pattern Scanning Laser Photocoagulator (PASCAL) and Pulsed Electron Avalanche Knife (PEAK) are in clinical use worldwide.
- OCT-guided Femtosecond Laser for Cataract Surgery received FDA and European approvals for clinical use.
Education
| 1996 - 1998: | Postdoctoral fellowship at Picosecond Free Electron Laser Center, Stanford University, CA, USA “Photo-induced transient optical elements for near-field IR microscopy” |
| 1989 - 1995: | Ph.D. in Physics (summa cum laude), Hebrew University of Jerusalem, Israel. Dissertation Title: "Photoablation of Soft Tissues Using Lensless Optics and its Applications to Medicine and Biology". |
| 1979 - 1984: | M.Sc. in Physics, Yerevan State University, USSR. Thesis: "Scattering of X-rays on Crystals with Various Types of Deformations" |
