MUDGETT LAB

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CURRENT LAB MEMBERS
 
Mary Beth Mudgett (Principal Investigator)

Ph.D. Department of Chemistry and Biochemistry, University of California, Los Angeles

Postdoctoral Scholar, Department of Plant and Microbial Biology, University of California, Berkeley

Jung-Gun Kim (Life Sciences Research Associate)

Ph.D., Department of Agricultural Biotechnology, Seoul National University, Korea

Postdoctoral Scholar, Department of Biology, Stanford University
Korea Science and Engineering Foundation Postdoctoral Fellow

I am interested in elucidating the biochemical function of type III seceretion effector proteins in Xanthomonas spp. Specifically, my work focuses on the mechanisms by which the XopD and XopN effectors suppress innate immune signaling in tomato during Xanthomonas pathogenesis.

 
Mi Sun Cheong (Postdoctoral Scholar)

B.S., Biochemistry and Mathematics,,Gyeongsang National University, Korea

M.S., Biochemistry, Gyeongsang National University, Korea

Ph.D., Plant Molecular Biology/Biotechnology, Purdue University and Gyeongsang National University, Korea

I am interested in determining how the Xanthomonas T3S effector AvrBsT activates effector-triggered immunity and lipid signaling during infection in Arabidopsis. I have discovered that AvrBsT possesses acetyltransferase activity and targets a novel microtubule-associated protein, ACIP1. My current goals are to determine how AvrBsT interferes with microbtuble dynamics during infection and to elucidate how ACIP1 functions during innate immune signaling using Arabidopsis as the model plant system.

 
Daniel Lanver (Postdoctoral Scholar)

Ph.D., Genetics, Philipps-University Marburg, Germany

Postdoctoral Scholar, Plant-Microbe Interactions, Max Planck Institute for Terrestrial Microbiology, Germany

Leopoldina Postdoctoral Research Fellow, 2012 - present

Plants harbor an innate immunity to defend against pathogen attacks. Successful pathogens have evolved strategies to circumvent the host immune system. One of these mechanisms relies on the function of the Xanthomonas campestris effector XopN. This effector targets the tomato atypical receptor kinase TARK1 to inhibit PAMP-triggered immune responses during Xanthomonas infection. My aim is to elucidate the TARK1-dependent signaling cascade and to define the molecular mechanism by which the bacterial effector XopN interferes with the defense signaling events during the early stages of infection.

William Stork (Graduate Student)

A.B. Dartmouth College

I am broadly interested in the defensive strategies that plants employ to protect themselves from pathogens, the cellular signaling networks that regulate plant defenses, and the trade-offs that plants face when trying to maximize fitness while dealing with stress. By studying how bacterial type III secretion effectors promote disease during infection and identifying effector targets in the host, I hope to uncover fundamental patterns underlying immune signaling networks in plants.

 
Hongxia Liu (Visiting Scholar)

Associate Professor, Nanjing Agricultural University, China

Research in my laboratory is focused on the biological control of plant diseases and induced plant resistance by rhizobacteria and molecular-associated moleculars patterns (MAMPs). I am also interested in how Xanthomonas species emply type III effector proteins to supress plant immunity . I am currently working on the regulation of TARK1 stability in tomato during Xanthomonas infection.

 
Mica Soriano (Undergraduate)
 
 
Jaime Rojas (Lab Assistant)
 
 
Franco Errico (Administrative Assistant)
 
 
ALUMNI
 
Visiting Scholars
Kalyan Mondal - Visiting Professor, Indian Agriculutral Research Institute, New Delhi
Jonathan Monroe - James Madison
 
Postdoctoral Fellows
Yajun Cao
Yanhui Chen - Beijing, China
Sebastien Cunnac - Montpellier Cedex, France
Angela Kirik - Illinois State University
Xinyan Li - Indiana University
 
Graduate Students
Julie Roden - PhD 2006 - Postdoctoral Scholar UCSF, current positions: lecturer at The Holy Cross
Kyle Taylor - PhD 2012
 
Masters Students
Abrahim El Gamal, Stanford Bioengineering Coterminal Student, current position: Scripps Institution of Oceanography, PhD program
Ken Frame - MS 2012, current position: Lake Pharma, Inc.
Bessie Su - Stanford Biology Coterminal Student, current position: UCSD PhD program
 
Research Technicians
Chris Aakre - Stanford University Honors Student, current position: MIT PhD Program
Andrew Hotson - Stanford University PhD from Microbiology and Immunology, current position: Postdoctoral Scholar Stanford School of Medicine
Jamie Nuwer - MD from UCLA Medical School, current position: Family Medicine/Sports Medicine, San Jose CA
Ariane Wilson - UCSF Pharmacy School, current position: Pharmacist, CA
 
High School Teachers
Wai-Pan Chan, Irvington High School
Claire Crossett, Life Academy of Health and Bioscience
Melissa Kindelspire, Castro Valley High School
 
Stanford Undergraduates
Brandis Belt
Vedita Bipat
Evelyn Chang
Alex Choo
Patrick Cordova
Margot Hedlin
Grace Laidlaw
Daniel Lee
Justin Levinson
Alex Nourishad
Devmin Pacihakkara
Seung Joon Park
Emily Pollock
Zarina Rahim
Zeke Richardson
Jason Ross
Lucy Schoen
Leroy Sims
Sushmita Sridhar
Allyson Stewart
Sean Voigt
 
Students from Other Universities
Gayathri Baranage - Sri Lanka
Thomas Tachibana - Wesleyan
Nathanie Trisnadi - UC Berkeley
Joe Vargas - CSU Hayward
Vanessa Wise - Ohlone College
 
High School Students
Amrita Dixit - Mountain View High School/ Duke University
Mark Keegan - Menlo School/ USC
Sara Kianian - Mountain View High School/ UC Berkeley
Jeri Ray - Palo Alto High School/ UCSD
Moniyka Sachar - Irvington High School
Daniel Shan - Palo Alto High School/ UC Berkeley
Derek Yecies - Menlo School/Boston University Medical School/Stanford School of Medicine