Welcome
Marina Sirota
Stanford Center for Biomedical Informatics Research
Medical School Office Building, X-215
251 Campus Drive
Stanford, CA 94305-5479
msirota@stanford.edu
I am a fourth year Ph.D. student in
the Biomedical Informatics
department at Stanford
University. Previously, I completed
a Biomedical Computation
undergraduate and Biomedical
Informatics coterminal masters degree at Stanford. Before then, I
attended Abraham Lincoln High
School.
As an undergraduate and masters student I
worked in Serafim
Batzoglou's laboratory. My previous work focused on computational
biology, more specifically developing algorithms for comparative
sequence analysis.
My current research advisor is Atul Butte. I am primarily
interested in developing computational methods in integrative biology
and applying these methods to study autoimmune disease.
I have been working on a novel approach to identify allele-specific
relationships between disease pairs based on genetic variation data
and applied it to study autoimmune disease. As a result we uncovered two
groupings of autoimmune disease where SNPs that make an individual
susceptible to one class of autoimmune disease also protect from
diseases in the other autoimmune class. I am also working on
systematically predicting drug-disease relationships based on gene
expression to identify novel therapeutic indications with a focus
on autoimmune disease.