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Publications

  1. PW Messer, DA Petrov (2013)
    Frequent adaptation and the McDonald-Kreitman test. PNAS (Early Edition).

    Featured on Haldane's Sieve: link . Most viewed item in November 2012: link

  2. PW Messer
    SLiM: Simulating Evolution with Selection and Linkage. Genetics (in revision).
  3. NR Garud, PW Messer, EO Buzbas, DA Petrov
    Soft selective sweeps are the primary mode of recent adaptation in Drosophila melanogaster. PLoS Biology (in revision).

    Featured on Haldane's Sieve: link

  4. DS Lawrie, PW Messer, R Hershberg, DA Petrov (2013)
    Strong purifying selection at synonymous sites in D.melanogaster.
    PLoS Genetics (in press).
  5. F Staubach, A Lorenc, PW Messer, K Tang, DA Petrov, D Tautz (2012)
    Genome patterns of selection and introgression of haplotypes in natural populations of the house mouse (mus musculus). PLoS Genet. 8:e100289

    Featured as a research highlight in Nature Reviews Genetics: link

  6. PW Messer, RA Neher (2012)
    Estimating the strength of selective sweeps from deep population diversity data. Genetics. 191:593
  7. D Sellis, BJ Callahan, DA Petrov, PW Messer (2011)
    Heterozygote advantage as a natural consequence of adaptation in diploids. PNAS. 108:20666

    Faculty of 1000 evaluation from Stephen Wright: link

    Summary on the Human Frontiers Science Program (HFSP) website: link

  8. DS Lawrie, DA Petrov, PW Messer (2011)
    Faster than neutral evolution of constrained sequences: the complex interplay of mutational biases and weak selection. Genome Biol Evol. 3:383

    Faculty of 1000 evaluation from Nicolas Galtier and Julien Dutheil: link

  9. TL Karasov*, PW Messer*, DA Petrov (2010)
    Evidence that adaptation in Drosophila is not limited by mutation at single sites. PLoS Genet. 6:e1000924 (*equal contribution)

    Perspective from Nick Barton: Understanding adaptation in large populations

    Faculty of 1000 evaluation from Michael Eisen and Devin Scannell: link

    Commentary in Nature Reviews Genetics by Mary Muers: Evolution: Rapid change explained by large populations

  10. J Gonzalez, TL Karasov, PW Messer, DA Petrov (2010)
    Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. PLoS Genet. 6:e1000905

    Faculty of 1000 evaluation from Ary Hoffmann: link

  11. PW Messer (2009)
    Measuring the rates of spontaneous mutation from deep and large-scale polymorphism data. Genetics. 182:1219

    Featured in the issue highlights and on the cover of Genetics' August 2009 issue: link

  12. J Gonzalez*, JM Macpherson*, PW Messer*, DA Petrov (2009)
    Inferring the strength of selection in Drosophila under complex demographic models. Mol Biol Evol. 26:513 (*equal contribution)
  13. N de la Chaux, PW Messer, PF Arndt (2007)
    DNA indels in coding regions reveal selective constraints on protein evolution in the human lineage. BMC Evol Biol. 7:191
  14. PW Messer, PF Arndt (2007)
    The majority of recent short DNA insertions in the human genome are tandem duplications. Mol Biol Evol. 24:1190
  15. PW Messer, R Bundschuh, M Vingron, PF Arndt (2007)
    Effects of long-range correlations in DNA on sequence alignment score statistics. J Comp Biol. 14:655
  16. PW Messer, R Bundschuh, M Vingron, PF Arndt (2006)
    Alignment statistics for long-range correlated genomic sequences. RECOMB 2006. 426
  17. PW Messer, PF Arndt (2006)
    CorGen -- measuring and generating long-range correlations for DNA sequence analysis. Nuc Acid Res. 34:W692
  18. PW Messer, M Lassig, PF Arndt (2005)
    Universality of long-range correlations in expansion-randomization systems. J Stat Mech. P10004
  19. PW Messer, PF Arndt, M Lassig (2005) Solvable sequence evolution models and genomic correlations. Phys Rev Lett. 94:138103

PhD thesis

Tandem Duplications in the Human Genome, Department of Mathematics, Free University Berlin, Supervisors: Martin Vingron and Peter Arndt

Diploma thesis

Solvable Sequence Evolution Models and Genomic Correlations, Institute for Theoretical Physics, University of Cologne, Supervisor: Michael Lassig