Laura Lazzeroni, PhD
Associate Professor in Psychiatry and Behavioral Sciences
(Biostatistics)
650-723-0947
SELECTED METHODOLOGICAL PAPERS
Allele
sharing and allelic association I: Sib
pair tests with increased power. Lazzeroni LC Genetic Epidemiology 22:328-344
Linkage disequilibrium and gene mapping: An empirical
least-squares approach. Lazzeroni LC. American
Journal of Human Genetics 62:159-170
A chronology of fine-scale gene mapping by linkage disequilibrium. Lazzeroni LC Statistical Methods in
Medical Research 10:57-76
A conditional inference framework for extending the transmission /
disequilibrium test. Lazzeroni LC,
Lange K Human Heredity 48:67-81
Markov
chains for
Plaid
models for gene expression data. Lazzeroni LC,
Owen A Statistica Sinica
12:61-86
Multipoint mapping
calculations for sperm-typing data. Lazzeroni LC,
Arnheim N, Schmitt K, Lange K American
Journal of Human Genetics 55:431-436
The global pairwise approach to radiation
hybrid mapping. Postscript File Tibshirani R, Lazzeroni L, Hastie T, Olshen A, Cox
D Technical Report No. 201 in the Stanford
Biostatistics Series
Random-effects
models for smoothing post-stratification weights. Lazzeroni LC, Little RJA Journal
of Official Statistics 14:61-78
Robustness of
multiple-imputation techniques to model misspecification. Lazzeroni LC, Schenker N, Taylor JMG. American
Statistical Association's 1990 Proceedings of the Survey Research Methods
Section, 260-265
Genome wide identification of genes conferring sensitivity
to the anti-cancer agents cisplatin,
oxaliplatin and mitomycin
C. Wu HI, Brown
JA, Dorie MJ, Lazzeroni LC, Brown JM Cancer Research 64:3940-3948
Cost effectiveness of screening for HIV in healthcare
settings in the era aof highly active antiretroviral
therapy (HAART). Sanders GD, Bayoumi AM, Sundaram V, Bilir SP,
Neukermans CP, Rydzak CE,
Douglass LR, Lazzeroni LC, Holodniy M, Owens DK
New England Journal of Medicine 352:570-585
Cytomegalovirus retinitis after initiation of highly
active antiretroviral therapy in HIV-infected patients: Nature history and
clinical predictors. Lin DY,
Warren J, Lazzeroni LC, Wolitz RA, Mansour S
Retina 22:268-277.
Accuracy,
precision and consistency of expert HIV-1 genotype interpretation: an
international comparison (The GUESS study). Zolopa AZ, Lazzeroni LC, Rinehart A, Vezinet FB, Clavel F, Collier A,
Conway B, Gulick RM, Holodniy M, Perno
C-F, Shafer RW, Richman DD, Weinberg M, Kuritzkes
D Clinical
Infectious Diseases 41:92-99
In vivo sequence diversity of the protease of the human
immunodeficiency virus type I: Presence
of protease inhibitor resistant variants in untreated subjects. Lech WJ, Wang G, Yang YL, Chee Y, Dorman K, McCrae D, Lazzeroni LC, Erickson JW, Sinsheimer J, Kaplan AH
Journal of Virology 70:2028-2043
Association of IL4R haplotypes
with type I diabetes. Mirel DB, Valdes AM, Lazzeroni
LC, Reynolds RL, Erlich HA, Noble JA Diabetes
51:3336-3341
A polymorphism in the
TCF7 gene, C883A, influences type 1 diabetes risk. Noble JA, White AM, Lazzeroni LC, Valdes AM, Mirel DB,
Reynolds R, Grupe A, Aud D, Peltz G, Erlich HA
Diabetes
Gene
expression patterns vary in clonal cell cultures from
Rett syndrome females with eight different MECP2
mutations. Traynor J, Agarwal P, Lazzeroni
LC, Francke U BMC
Medical Genetics 3:12
The role of a common adenosine monophosphate
deaminase (AMPD)-1 polymorphism in outcome of
ischemic and non-ischemic heart failure. Kolek MJ, Carlquist
JF, Thaneemit-Chen S, Lazzeroni LC, Whiting BM, Horne BD, Muhlestein
JB, Lavori P, Anderson JL Journal of Cardiac Failure in press
Genomics
A high-resolution radiation hybrid map
of the human genome draft sequence. Olivier M. et al. Science 292:1298-1302
Statistical refinement of primer design parameters. Beasley EM, Myers RM, Cox DR, Lazzeroni
LC PCR
Applications: Protocols for Functional Genomics Innis M, Gelfand D, Sninsky J, editors, Academic Press
Individual variation in recombination in human males. Yu J, Lazzeroni L, Qui J, Huang M, Navidi W, Erlich H, Arnheim
N American
Journal of Human Genetics 59:1186-1192
A multipoint linkage map of the human pseudoautosomal region based on single sperm typing: Do
double crossovers occur during male meiosis?
Schmitt K, Lazzeroni LC, Foote S, Vollrath D, Fisher
EMC, Goradia TM, Lange K, Page DC, Arnheim N American
Journal of Human Genetics 55:423-430
ESP: A set of MatLab
functions for the elliptical sib pair test as described in “Allele sharing and
allelic association I: Sib pair tests
with increased power.”
PLAID: A Windows-based C program for finding plaid
models from DNA microarray and other data as
described in "Plaid models for gene expression data."
ELS: A set of SPLUS functions for empirical least
squares methods for fine-mapping of genetic loci as described in "Linkage
Disequilibrium and Gene Mapping: An Empirical Least Squares Approach" in American Journal of Human Genetics, 62:159-170.
SPERM: Available at http://www.biomath.medsch.ucla.edu/faculty/klange/software.html A FORTRAN 77 written with
Ken Lange for likelihood linkage analysis of
multipoint sperm typing data as described in "Multipoint Mapping
Calculations for Sperm Typing Data" in American Journal of Human Genetics, 55:431-436.