---

Chemical control of laryngeal vascular resistance in anesthetized dogs
Phrase: +455 +/- 110% systemic hypoxia induced by breathing 8% o2-n2 increased
Inducers of gene: 8%
Inducers of gene: o2-n2

---

The neglected prehospital phase of head injury: apnea and catecholamine surge
Phrase: 600 that were pertinent apnea induced by head injury produces hypoxia
Induced genes: apnea

---

Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis
Phrase: cells from hypoxia and neurotrophin-withdrawal induced apoptosis cheng ag
Induced genes: ag

---

Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation
Phrase: 15;5924:6046-51 hypoxia induces p53 accumulation through mdm2 down-regulation
Phrase: in ionizing radiation hypoxia readily induces the nuclear accumulation of p53
Induced genes: p53
Induced genes: mdm2
Induced genes: p53

---

Hypoxia, Metabolic Inhibition, and Isolated Rat Mesenteric Tone: Influence of Arterial Diameter
Phrase: the effects of severe hypoxia induced by either substitution of o2
Inducers of gene: o2

---

[Heme as a signaling molecule under environmental stress]
Phrase: of hypoxia inducible factor-1 which induces expression of genes encoding erythropoietin
Induced genes: erythropoietin

---

Hypoxic Repression of Lactate Dehydrogenase-B in Retina
Phrase: to elucidate mechanisms controlling hypoxia induced gene repression in the retina
Induced genes: retina

---

Brainstem activation of platelet-derived growth factor-beta receptor modulates the late phase of the hypoxic ventilatory response
Phrase: pdgf-b chain mrna expression was induced by hypoxia in the nucleus
Induced genes: pdgf-b

---

Chronic Hypoxia Induces Exaggerated Growth Responses in Pulmonary Artery Adventitial Fibroblasts
Phrase: chronic hypoxia induces exaggerated growth responses in pulmonary
Induced genes: exaggerated

---

Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells
Phrase: mimics of cellular hypoxia similarly stimulated vegf mrna expression and secretion
Phrase: after in vivo injury hypoxia stimulates cell signaling in stellate cells
Induced genes: stellate

---

Effects of in vivo sodium azide administration on the immunohistochemical localization of kynurenine aminotransferase in the rat brain
Phrase: kynurenine aminotransferase-i the chemical hypoxia induced by mitochondrial toxins produces a
Inducers of gene: mitochondrial
Inducers of gene: toxins

---

Tissue oxygen levels control astrocyte movement and differentiation in developing retina
Phrase: not accelerate migration conversely hypoxia induced unstellated astrocytes to stellate within
Induced genes: unstellated
Induced genes: stellate

---

Anesthetic managements of the patients with giant mediastinal tumors--a report of two cases
Phrase: compresses the trachea and bronchus induces hypoxia and asphyxia eventuating in
Inducers of gene: compresses
Inducers of gene: trachea
Inducers of gene: bronchus

---

An animal model of the relationship between systemic hypertension and repetitive episodic hypoxia as seen in sleep apnoea
Phrase: is that recurrent episodic hypoxia stimulates chemoreceptors which in turn cause
Induced genes: chemoreceptors

---

Egr-1 mediates transcriptional activation of IGF-II gene in response to hypoxia
Phrase: system in this system hypoxia induced a linear increase within 24
Induced genes: linear

---

Hypoxia, the subsequent systemic metabolic acidosis, and their relationship with cerebral metabolite concentrations: An in vivo study in fetal lambs with proton magnetic resonance spectroscopy
Phrase: spectroscopystudy design: fetal hypoxia was induced in 6 fetal lambs by
Induced genes: lambs

---

Role of nitric oxide in hypoxia inhibition of fever
Phrase: in hypoxia-induced hypothermia hypoxia also inhibits lipopolysaccharide lps-induced fever we tested
Repressed genes: lipopolysaccharide
Repressed genes: lps-induced
Repressed genes: fever

---

Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells
Phrase: aovsm cells interestingly hypoxia neither induced ho-1 gene expression nor increased
Induced genes: ho-1

---

Apoptosis in vascular endothelial cells caused by serum deprivation, oxidative stress and transforming growth factor-beta
Phrase: protein or sfm plus hypoxia induced greatest levels of apoptosis tgf-beta1
Induced genes: greatest

---

Changes in the constant potential in brain structures in rats during focal ischemia and systemic hypoxia
Phrase: artery mca and systemic hypoxia induced by 08% carbon monoxide co
Inducers of gene: 08%
Inducers of gene: monoxide
Inducers of gene: co

---

Induction of hypoxia-inducible factor-1
Phrase: is a heterodimeric transcription factor induced by hypoxia that is composed
Phrase: target gene induction because hypoxia induces hif-1 in other tissues systemic
Induced genes: heterodimeric
Induced genes: hif-1

---

A global hypoxia preconditioning model: neuroprotection against seizure-induced specific gravity changes
Phrase: to examine the neuroprotective mechanisms induced by global hypoxia preconditioning against
Induced genes: neuroprotective

---

ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells
Phrase: heart-derived h9c2 cells from apoptosis induced by hypoxia a component of
Induced genes: heart-derived
Induced genes: h9c2

---

Formation of dense erythrocytes in SAD mice exposed to chronic hypoxia: evaluation of different therapeutic regimens and of a combination of oral clotrimazole and magnesium therapies
Phrase: in the sad mice hypoxia induced significant cell dehydration these hypoxia-induced
Induced genes: dehydration
Induced genes: hypoxia-induced

---

Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes
Phrase: pai-1 mrna and protein were induced by mild hypoxia 8% o2
Induced genes: pai-1

---

Hypoxia increases glyceraldehyde-3-phosphate dehydrogenase transcription in rat alveolar epithelial cells
Phrase: expression in atii cells hypoxia induced a time- and o2 concentration-dependent
Phrase: these results indicate that hypoxia induces gapdh expression in atii cells
Induced genes: o2
Induced genes: concentration-dependent
Induced genes: atii

---

Glutamate in synaptic terminals is reduced by lack of glucose but not hypoxia in rat hippocampal slices
Phrase: many terminals hypoxia and hypoglycemia induced similar atp-dependent releases of glutamate
Induced genes: atp-dependent
Induced genes: glutamate

---

Ischemic
Phrase: we focused on ischemic tolerance induced by hypoxia and hyperthermia in
Phrase: whole-body hyperthermia or hypoxia was induced 24 h prior to the
Induced genes: h

---

Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes
Phrase: them only vegf-a mrna was induced under hypoxia competitive reverse transcription-polymerase
Inducers of gene: vegf-a

---

Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo
Phrase: hypoxia specifically acute hypoxic stress induced a significant increase 360% of
Induced genes: 360%

---

Hypoxia upregulates activity and expression of the glucose transporter GLUT1 in alveolar epithelial cells
Phrase: dec;216:710-8 hypoxia upregulates activity and expression of the
Phrase: mechanisms of this regulation hypoxia induced a stimulation of na-independent glucose
Phrase: hypoxia 18 h 0% o2 induced a 3-fold increase of glucose
Induced genes: na-independent

---

Chronic carbon monoxide exposure in vivo induces myocardial endothelin-1 expression and hypertrophy in rat
Phrase: effects is unknown carbon monoxide induces hypoxia and there is evidence
Inducers of gene: monoxide

---

Physiological adjustments and arteriolar remodelling within skeletal muscle during acclimation to chronic hypoxia in the rat
Phrase: breathing 8 % o2 hypoxia induced similar increases in mvc in
Induced genes: mvc

---

Prolonged hypoxic stress increases adrenal cholesterol reserve in rats without causing adrenal hypertrophy
Phrase: known that in rats hypoxia stimulates adrenal steroidogenesis but our understanding
Induced genes: adrenal

---

Hypoxia-induced changes in extracellular matrix metabolism in renal cells
Phrase: show that hypoxia 1% o2 induces a fibrogenic phenotype in human
Induced genes: fibrogenic

---

Increased sensitivity to damaging effects of hypoxia and anoxia of isolated hearts from rats after prolonged exposure to ethanol: apparent protection by nitrendipine
Phrase: langendorff perfusion system hypoxia was induced by perfusion with krebs-henseleit buffer
Inducers of gene: krebs-henseleit
Inducers of gene: buffer

---

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction
Phrase: in hypoxia since it is inhibited in the presence of geldanamycin
Repressed genes: geldanamycin

---

Tumor necrosis factor-alpha enhances hypoxia-reoxygenation-mediated apoptosis in cultured human coronary artery endothelial cells: critical role of protein kinase C
Phrase: vs hypoxia alone tnf alpha induced concentration-dependent apoptosis and enhanced reoxygenation-mediated
Induced genes: concentration-dependent
Induced genes: reoxygenation-mediated

---

Roles of ion channels in carotid body chemotransmission of acute hypoxia
Phrase: rats ca2+-activated k+ channels are inhibited by hypoxia the role of
Repressed genes: ca2+-activated
Repressed genes: k+

---

CPP32
Phrase: activity of caspase-3 was progressively stimulated by lethal hypoxia as reflected
Induced genes: caspase-3

---

Role of cytochrome P-450 4A in oxygen sensing and NO production in rat cremaster resistance arteries
Phrase: production by the endothelium hypoxia induces an no-mediated dilation when cytochrome
Induced genes: no-mediated
Induced genes: dilation

---

Hypoxia stimulates proliferation and interleukin-1alpha production in human vascular smooth muscle cells
Phrase: 2:h1326-37 hypoxia stimulates proliferation and interleukin-1alpha production in
Induced genes: interleukin-1alpha

---

21-aminosteroids prevent the down-regulation of hepatic cytochrome P450 induced by hypoxia and inflammation in conscious rabbits
Phrase: down-regulation of hepatic cytochrome p450 induced by hypoxia and inflammation in
Phrase: of hepatic cytochrome p450 p450 induced by acute moderate hypoxia or
Induced genes: p450
Induced genes: p450
Induced genes: p450

---

Relationship between mixed venous oxygen saturation and markers of tissue oxygenation in progressive hypoxic hypoxia and in isovolemic anemic hypoxia in 8- to 12-day-old piglets
Phrase: flow progressive hypoxic hypoxia was induced by decreasing fio2 from baseline
Phrase: 010 progressive anemic hypoxia was induced by a repeated isovolemic exchange
Inducers of gene: fio2
Inducers of gene: baseline
Inducers of gene: isovolemic

---

Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia
Phrase: universitat leipzig germany morphological changes induced by 30 min of hypoxia
Phrase: completely prevented the morphological damage induced by hypoxia whereas tolbutamide 300
Induced genes: leipzig

---

Short hypobaric hypoxia and breathing pattern: effect of positive end expiratory pressure
Phrase: that hypoxia compared with normoxia induces increases in tidal volume vt
Induced genes: tidal
Induced genes: vt

---

[The usefulness of tracheostomy in Duchenne muscular dystrophy ventilated by a chest respirator]
Phrase: pharyngeal hypotonia during rem sleep induces periodic nocturnal hypoxia therefore the
Inducers of gene: pharyngeal
Inducers of gene: hypotonia
Inducers of gene: rem
Inducers of gene: sleep

---

Inhibition of baroreflex vagal bradycardia by selective stimulation of arterial chemoreceptors in rats
Phrase: we reported recently that hypoxia inhibits baroreflex vagal bradycardia bvb in
Repressed genes: baroreflex
Repressed genes: vagal
Repressed genes: bradycardia
Repressed genes: bvb

---

Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease
Phrase: sep;799:1089-99 hypoxia induces renal tubular epithelial cell apoptosis
Phrase: apoptosis to determine whether hypoxia stimulates fas-dependent apoptosis rtcs were cultured
Phrase: progressive renal disease chronic hypoxia stimulates fas-dependent rtc apoptosis which represents
Induced genes: fas-dependent
Induced genes: rtcs
Induced genes: fas-dependent
Induced genes: rtc

---

Hypoxic cervical cancers with low apoptotic index are highly aggressive
Phrase: from experimental work that hypoxia induces apoptosis in apoptosis-sensitive neoplastic cells
Induced genes: apoptosis-sensitive

---

Effect of allopurinol on hypoxia-induced modification of the NMDA receptor in newborn piglets
Phrase: hypoxic piglets cerebral hypoxia was induced by lowering the fio2 to
Inducers of gene: lowering
Inducers of gene: fio2

---

Oxygen sensitivity of cloned voltage-gated K
Phrase: kv93 alpha subunits were reversibly inhibited by hypoxia in the voltage
Phrase: expressed alone moreover hypoxia reversibly inhibited kv12/kv15 current activated at physiologically
Phrase: indicate that 1 hypoxia reversibly inhibits kv12 and kv21 but not
Phrase: and kv21/kv93 heteromeric channels are inhibited by hypoxia in the voltage
Repressed genes: kv93
Repressed genes: kv12/kv15
Repressed genes: kv12
Repressed genes: kv21
Repressed genes: kv21/kv93
Repressed genes: heteromeric

---

Cardiovascular and respiratory reflexes: the tropical fish, traira
Phrase: vascular resistance during hypoxia hypoxia induced increases in ventilation frequency arose
Induced genes: ventilation
Induced genes: ventilation

---

Synthesis and pharmacological investigation of 9-methyl-1,2,3,4,6,7,12,12b-octahydro-7-oxo-indolo[2,3-a]quinolizine
Phrase: from both hypobaric and cyanide induced hypoxia in mice these activities
Inducers of gene: hypobaric
Inducers of gene: cyanide

---

[Mechanism of action of cicletanine on the relationship between endothelium and vascular smooth muscle in the rat thoracic aorta under normoxic and hypoxic conditions]
Phrase: 10-7 m and hypoxia was induced by switching gas mixture from
Inducers of gene: switching
Inducers of gene: gas

---

Role of adenosine in regulation of brain temperature in fetal sheep
Phrase: hypoxia study design: hypoxia was induced by occluding the umbilical cord
Inducers of gene: occluding
Inducers of gene: umbilical
Inducers of gene: occluding
Inducers of gene: umbilical

---

Hypoxia downregulates tropoelastin gene expression in rat lung fibroblasts by pretranslational mechanisms
Phrase: 1:l566-72 hypoxia downregulates tropoelastin gene expression in rat
Phrase: variety of o2 conditions hypoxia downregulated tropoelastin mrna in a dose-
Phrase: d abrogated this effect hypoxia induced early decreases in tropoelastin mrna
Induced genes: tropoelastin
Repressed genes: tropoelastin
Repressed genes: tropoelastin

---

l-Deprenyl, blocking apoptosis and regulating gene expression in cultured retinal neurons
Phrase: suggest that l-deprenyl blocks apoptosis induced by hypoxia as well as
Induced genes: l-deprenyl

---

Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFkappaB-dependent inducible nitric oxide synthase and cyclooxygenase-2
Phrase: aug-sep;1258-9:525-8 hypoxia induces pivotal tumor angiogenesis control factors
Induced genes: pivotal

---

Expression of inducible nitric oxide synthase immunoreactivity in rat brain following chronic hypoxia: effect of aminoguanidine
Phrase: role in the neuropathological alterations induced by chronic hypoxia
Induced genes: neuropathological

---

Muscle venous PO2 and VO2 are linearly related in repetitive tetanic contractions of canine muscle during hypoxic hypoxia
Phrase: to those obtained during hypoxia induced by high o2-affinity-erythrocytes we conclude
Inducers of gene: o2-affinity-erythrocytes

---

Induction of cardiac nitric oxide synthase 2 in rats exposed to chronic hypoxia
Phrase: left ventricle lv chronic hypoxia induced rv hypertrophy: the rv weight
Phrase: in the heart nos2 is upregulated by hypoxia with an expression
Induced genes: hypertrophy:
Induced genes: nos2

---

The modification of breathing behavior
Phrase: that result from cerebral hypoxia induced by conditioned hyperventilation publication types:
Inducers of gene: conditioned
Inducers of gene: hyperventilation

---

Hypoxia- and hypercapnia-induced DC potential shifts in rat at the scalp and the skull are opposite in polarity to those at the cerebral cortex
Phrase: dc direct current potential shifts induced by hypoxia or hypercapnia for
Phrase: the cerebral cortex hypoxia was induced by decreasing the inspiratory o2
Inducers of gene: inspiratory
Inducers of gene: o2

---

Sudden infant death syndrome: hypothalamic failure to sense elevated blood pyrogens
Phrase: mouse thymocytes fetal haemoglobin hbf induces hypoxia which is a stimulator
Inducers of gene: haemoglobin
Inducers of gene: hbf

---

Role of NO in recovery from neonatal hypoxic pulmonary hypertension
Phrase: days of recovery the hypoxia induced right ventricular hypertrophy and pulmonary
Induced genes: right

---

[Effect of L-arg and SNP on pulmonary arterial pressure and vascular structural changes of chronically hypoxic rats]
Phrase: the development of pulmonary hypertension induced by chronic hypoxia
Induced genes: hypertension

---

Effects of the endothelin ET
Phrase: endothelin-1-induced maximum contractions were significantly inhibited by exposure to hypoxia in
Phrase: arterial strips the hypoxia also induced right ventricular hypertrophy in rats
Induced genes: right
Repressed genes: endothelin-1-induced
Repressed genes: contractions

---

Hypoxia induces activation and subcellular translocation of focal adhesion kinase
Phrase: 19;2621:290-6 hypoxia induces activation and subcellular translocation of
Phrase: here we show that hypoxia induced tyrosine phosphorylation of p125fak and
Induced genes: p125fak

---

Transferrin receptor induction by hypoxia
Phrase: experiments and supershift assays was induced in hep3b cells by hypoxia
Inducers of gene: supershift

---

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
Phrase: during ischemia and hypoxia is stimulated by the translocation of glut-4
Inducers of gene: glut-4

---

Selective activation of p38alpha and p38gamma by hypoxia
Phrase: moderate hypoxia 5% o2 progressively stimulated phosphorylation and activation of p38gamma
Phrase: protein kinase prolonged hypoxia also induced phosphorylation and activation of p42/p44
Induced genes: p38gamma
Induced genes: p42/p44

---

Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death
Phrase: death both apoptosis and necrosis induced by hypoxia in naive and
Phrase: and nac activation of caspase-3 induced by hypoxia was also inhibited
Phrase: induced by hypoxia was also inhibited by either gsh or nac
Induced genes: nac
Induced genes: caspase-3
Repressors of gene: gsh
Repressors of gene: nac

---

Hypoxia induces selective SAPK
Phrase: aug;732:665-74 hypoxia induces selective sapk/jnk-2-ap-1 pathway activation in
Induced genes: sapk/jnk-2-ap-1

---

Hypoxia inhibits macrophage migration
Phrase: jul;297:2280-7 hypoxia inhibits macrophage migration turner
Phrase: study we show that hypoxia inhibits mcp-1-induced migration of thp-1 monocytic
Phrase: limited to mcp-1 hypoxia also inhibited the chemotactic response to macrophage
Repressed genes: macrophage
Repressed genes: migration
Repressed genes: turner
Repressed genes: mcp-1-induced
Repressed genes: migration
Repressed genes: thp-1
Repressed genes: chemotactic
Repressed genes: macrophage

---

HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5
Phrase: others hif1a gene expression is upregulated by hypoxia in this report
Phrase: hypoxia hif1a gene expression is upregulated through a short sequence located
Induced genes: hif1a

---

Cerebral artery blood velocity in normal subjects during acute decreases in barometric pressure
Phrase: changes decreases in barometric pressure induced hypoxia and hypocapnia when normalizing
Inducers of gene: barometric

---

Retinal ganglion cell dysfunction induced by hypoxia and glutamate: potential neuroprotective effects of beta-blockers
Phrase: retinal ganglion cell dysfunction induced by hypoxia and glutamate: potential
Induced genes: retinal
Induced genes: ganglion

---

Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1
Phrase: hif-1 target genes was not induced by hypoxia in embryonic stem
Induced genes: hif-1

---

Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila
Phrase: to hypoxia hypoxic exposure rapidly induced exploratory behavior in larvae and
Induced genes: exploratory
Induced genes: larvae

---

Effects of acute and chronic hypoxia on nitric oxide-mediated relaxation of fetal guinea pig arteries
Phrase: 10-4 mol/l results: acute hypoxia inhibited endothelium-dependent relaxation in response to
Repressed genes: endothelium-dependent

---

Plasma membrane phospholipid integrity and orientation during hypoxic and toxic proximal tubular attack
Phrase: naja pla2 exposure results: hypoxia induced approximately 60% ldh release but
Phrase: intracellular pla2 b exogenous pla2 induces pl losses during hypoxia but
Induced genes: 60%
Induced genes: ldh
Inducers of gene: pla2
Inducers of gene: b
Inducers of gene: pla2

---

Tyrosine kinase inhibitors modulate the ventilatory response to hypoxia in the conscious rat
Phrase: min we conclude that hypoxia induces tyrosine phosphorylation of the n-methyl-d-aspartate
Induced genes: n-methyl-d-aspartate

---

Hypoxia during early developmental period induces long-term changes in the dopamine content and release in a mesencephalic cell culture
Phrase: hypoxia during early developmental period induces long-term changes in the dopamine
Induced genes: dopamine

---

Mg2
Phrase: decrease in cerebral energy metabolism induced by hypoxia studies were performed
Induced genes: energy

---

Hypoxia induces free radical damage to rat erythrocytes and spleen: analysis of the fluorescent end-products of lipid peroxidation
Phrase: jun;316:671-81 hypoxia induces free radical damage to rat
Phrase: studies have shown that hypoxia induces alterations in the lipid membranes
Phrase: hypoxia for various time periods induced formation of lipophilic fluorescent products
Induced genes: lipophilic

---

Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells
Phrase: consistently a dominant negative mek1 inhibited telomerase activation by hypoxia finally
Phrase: a stress response against genotoxicity induced by hypoxia copyright 1999 academic
Repressors of gene: mek1

---

Hypoxia stimulates cerebral blood flow in the estuarine crocodile
Phrase: 21;2671:1-4 hypoxia stimulates cerebral blood flow in the
Phrase: did not affect the hypoxia induced increase in cbf we conclude
Induced genes: cbf

---

Taurine antagonizes calcium overload induced by glutamate or chemical hypoxia in cultured rat hippocampal neurons
Phrase: taurine antagonizes calcium overload induced by glutamate or chemical hypoxia
Induced genes: taurine
Induced genes: overload

---

Relationship between hypoxemia and fibrillation potential firing rate in denervated muscle
Phrase: digitorum longus muscle hypoxia was induced by low-oxygen ventilation ischemia was
Inducers of gene: low-oxygen
Inducers of gene: ventilation

---

Plasticity in the phenotypic expression of catecholamines and vasoactive intestinal peptide in adult rat superior cervical and stellate ganglia after long-term hypoxia in vivo
Phrase: intact stellate ganglion hypoxia alone induced a 15-fold increase in the
Induced genes: 15-fold

---

Picroliv -- a natural product protects cells and regulates the gene expression during hypoxia
Phrase: treatment with picroliv during hypoxia inhibited vegf and hif-1 expression in
Repressed genes: hif-1

---

Near infrared spectroscopy-measured changes in cerebral blood volume and cytochrome aa3 in newborn lambs exposed to hypoxia and hypercapnia, and ischemia: a comparison with changes in brain perfusion and O2 metabolism
Phrase: combined hypoxia and hypercapnia was induced by ventilation with 6-8% of
Inducers of gene: ventilation
Inducers of gene: 6-8%

---

K
Phrase: transmitter the initial step hypoxia induced depolarization may be mediated by
Induced genes: depolarization

---

[Expression and distribution of bFGF in rat lung tissue of chronic hypoxic pulmonary hypertension]
Phrase: rat models with chronic hypoxia induced pulmonary hypertension were established the
Induced genes: hypertension

---

Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy
Phrase: in vitro findings that hypoxia downregulated vascular hgf production vascular hgf
Repressed genes: hgf
Repressed genes: hgf

---

Hypoxia and cAMP stimulate vascular endothelial growth factor
Phrase: was determined by elisa hypoxia stimulated vegf mrna in decidualized stromal
Induced genes: decidualized
Induced genes: stromal

---

Hypoxia inhibits the synthesis of phosphoinositides in the rabbit carotid body
Phrase: may;4376:839-45 hypoxia inhibits the synthesis of phosphoinositides in
Phrase: 3h-pis from 3h-myo-inositol was markedly inhibited by hypoxia in the cb
Repressed genes: phosphoinositides
Repressed genes: 3h-pis
Repressed genes: 3h-myo-inositol

---

Acute hypoxic pulmonary vasoconstriction in conscious dogs decreases renin and is unaffected by losartan
Phrase: pg/ml the renin-angiotensin system is inhibited during acute hypoxia despite sympathetic
Repressors of gene: pg/ml

---

Mechanisms of hypoxic coronary vasodilatation in isolated perfused rat hearts
Phrase: suggests that hypoxia almost completely inhibits no production and that katp
Repressed genes: katp

---

Post-treatment dopexamine infusions partially reverse reductions in cranial mesenteric blood flow and mucosal oxygenation induced by hypoxia in newborn piglets
Phrase: blood flow and mucosal oxygenation induced by hypoxia in newborn piglets
Induced genes: oxygenation

---

[Ethanol-induced hepatic microcirculatory disturbance]
Phrase: that ethanol at higher concentrations induces hypoxia in the liver by
Inducers of gene: ethanol

---

Differentiation and assessment of cell death
Phrase: hypoxia model and the anti-5a9 induced oncosis model were not as
Induced genes: oncosis

---

Effects of oxygen deprivation on parapyramidal neurons of the ventrolateral medulla in the rat
Phrase: the mechanisms involved in hypoxia induced respiratory depression the responses of
Induced genes: depression

---

Short-term hypoxia downregulates epithelial cell desquamation in vivo, but does not increase Pseudomonas aeruginosa adherence to exfoliated human corneal epithelial cells
Phrase: short-term hypoxia downregulates epithelial cell desquamation in vivo
Phrase: time that short-term precorneal hypoxia downregulates corneal epithelial cell desquamation in
Repressed genes: corneal

---

Acute and chronic blood pressure response to recurrent acoustic arousal in rats
Phrase: and duration as episodic hypoxia induces elevated bp we exposed 14-week-old
Induced genes: bp
Induced genes: 14-week-old

---

Hypoxia upregulates VEGF production in keloid fibroblasts
Phrase: 519-20 hypoxia upregulates vegf production in keloid fibroblasts
Phrase: the importance of matrix accumulation stimulated by hypoxia or 4 increased
Induced genes: keloid

---

Hypoxia-associated induction of early growth response-1 gene expression
Phrase: of egr-1 transcription indeed hypoxia induced activation of elk-1 and suppression
Phrase: egr-1 in response to hypoxia induces a different facet of the
Induced genes: elk-1
Induced genes: facet

---

Cerebral blood flow during treatment for pulmonary hypertension
Phrase: term newborn piglets with hypoxia induced pulmonary hypertension were randomly assigned
Induced genes: hypertension

---

Hypoxia-mediated regulation of gene expression in mammalian cells
Phrase: and tyrosine hydroxylase are all induced by hypoxia recent studies demonstrated
Induced genes: hydroxylase

---

Downregulation of Na
Phrase: results demonstrate that normobaric hypoxia induced during exercise training represents a
Induced genes: exercise
Induced genes: training

---

Effect of cAMP on the activity and the phosphorylation of Na
Phrase: a2 pla2 activation a pathway stimulated by hypoxia we evaluated the
Induced genes: a2
Induced genes: pla2

---

Hypoxia induces differential changes of dopamine metabolism in mature and immature mesencephalic and diencephalic cell cultures
Phrase: 1999;1062:111-22 hypoxia induces differential changes of dopamine metabolism
Phrase: alterations of dopamine da metabolism induced by hypoxia could contribute to
Phrase: long-term behavioral and/or neurological abnormalities induced by perinatal hypoxia
Induced genes: dopamine
Induced genes: dopamine
Induced genes: behavioral

---

[Central apnea with consciousness impairment due to Listeria rhombencephalitis sequelae]
Phrase: neither acidosis hypoxia nor hypercapnea stimulated the respiratory centers during episodes
Induced genes: episodes

---

Gene delivery of Kir6
Phrase: metabolic stress ca2+ loading was induced by ca2+ influx during hypoxia
Induced genes: loading

---

Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice
Phrase: apr;1038:r23-9 hypoxia induces severe right ventricular dilatation and
Induced genes: right
Induced genes: dilatation

---

Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways
Phrase: dre driven transcription was markedly inhibited by hypoxia and that hypoxia
Phrase: activation of the hypoxia pathway inhibited cyp1a1 up-regulation but that activation
Repressed genes: dre
Repressed genes: dre
Repressed genes: cyp1a1

---

Hypoxia induces c-Fos protein expression in NMDA but not AMPA glutamate receptor labeled neurons within the nucleus tractus solitarii of the conscious rat
Phrase: 5;2622:93-6 hypoxia induces c-fos protein expression in nmda
Induced genes: c-fos
Induced genes: nmda

---

Developmental aspects and mechanisms of rat caudal hypothalamic neuronal responses to hypoxia
Phrase: in the caudal hypothalamus are stimulated by hypoxia both in vivo
Phrase: the mechanism by which hypoxia stimulates caudal hypothalamic neurons caudal hypothalamic
Phrase: groups those cells that were stimulated by hypoxia demonstrated a significant
Induced genes: caudal
Induced genes: hypothalamus
Induced genes: caudal
Induced genes: hypothalamic
Induced genes: caudal
Induced genes: hypothalamic

---

Hypoxia induces permeability in brain microvessel endothelial cells via VEGF and NO
Phrase: 1:c812-20 hypoxia induces permeability in brain microvessel endothelial
Induced genes: permeability

---

Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs
Phrase: 1:l571-81 hypoxia inhibits increased etb receptor-mediated no synthesis
Phrase: exposure is unclear because hypoxia inhibits no synthesis in normotensive lungs
Repressed genes: etb
Repressed genes: receptor-mediated
Repressed genes: normotensive
Repressed genes: lungs

---

Influence of hypoxia and hyperoxia on the cardiovascular and lethal effects of ethanol
Phrase: thus decrease in vascular contractility induced by hypoxia combined with ethanol-induced
Induced genes: contractility

---

Carbon monoxide, a cyclic GMP-related messenger, involved in hypoxic bronchodilation in vivo
Phrase: structures whereas ho-1 can be induced by several factors including hypoxia
Induced genes: ho-1

---

Possible involvement of p38 MAP kinase in HSP70 expression induced by hypoxia in rat primary astrocytes
Phrase: map kinase in hsp70 expression induced by hypoxia in rat primary
Induced genes: hsp70

---

Correlation of flow probe determinations of common carotid artery blood flow and internal carotid artery blood flow with microsphere determinations of cerebral blood flow in piglets
Phrase: a 5-fold range of cbf induced by hypercarbia or hypoxia r
Induced genes: cbf

---

Hypoxia inhibits baroreflex vagal bradycardia via a central action in anaesthetized rats
Phrase: jan;841:47-56 hypoxia inhibits baroreflex vagal bradycardia via a
Phrase: that baroreflex vagal bradycardia is inhibited by hypoxia and the inhibition
Repressed genes: baroreflex
Repressed genes: vagal
Repressed genes: bradycardia
Repressed genes: baroreflex
Repressed genes: vagal
Repressed genes: bradycardia

---

Vascular endothelial growth factor expression in human neuroblastoma: up-regulation by hypoxia
Phrase: of neuroblastoma cells to hypoxia induces a marked increase in bioactive
Induced genes: bioactive

---

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha
Phrase: maryland 21287-3914 usa chronic hypoxia induces polycythemia pulmonary hypertension right ventricular
Induced genes: hypertension
Induced genes: right

---

[Regulation of cardiovascular myogenic tone via G-protein-sensitive transmembrane signal pathways]
Phrase: results indicated that 1 hypoxia inhibited the na+-ca2+ exchange protein induced
Phrase: such as na+-ca2+ exchange protein induced by hypoxia
Induced genes: na+-ca2+
Repressed genes: na+-ca2+

---

[Effects of hypoxia on the morphology and proliferation of cultured pulmonary arterial smooth muscle cell]
Phrase: pasm dna synthesis was significantly stimulated by 24 h hypoxia p
Phrase: dna analysis revealed that hypoxia induced significant enhancement of g2/m phase
Induced genes: pasm

---

Temporary amnesia induced by cold anesthesia and hypoxia in Drosophila
Phrase: temporary amnesia induced by cold anesthesia and hypoxia
Induced genes: amnesia

---

[Effects of hypoxia and taurine on vasoconstriction peptides from cultured bovine pulmonary arterial endothelial cells]
Phrase: expression paec cultured under hypoxia induced increase in et-1 at-ii and
Induced genes: et-1
Induced genes: at-ii

---

Identification of the poly
Phrase: hep3b or hepg2 cells hypoxia induces neither expression of pcbp nor
Induced genes: pcbp

---

Intermittent hypobaric hypoxia stimulates erythropoiesis and improves aerobic capacity
Phrase: intermittent hypobaric hypoxia stimulates erythropoiesis and improves aerobic capacity
Induced genes: erythropoiesis
Induced genes: improves
Induced genes: aerobic

---

Modulatory effect of blood cells on hypoxic vasoconstriction response and nitric oxide release in rat lungs
Phrase: out in each experiment hypoxia induced pulmonary vasoconstriction as reflected by
Induced genes: vasoconstriction

---

The influence of the neuropeptide galanin on the contractility and the effective refractory period of guinea-pig heart papillary muscle under normoxic and hypoxic conditions
Phrase: of erp although simulated hypoxia induced a significant drop in fc
Induced genes: drop
Induced genes: fc

---

Endothelial cell responses to hypoxic stress
Phrase: feedback on and modulate signals induced by hypoxia and vice versa
Phrase: reversing the production of vasoconstrictors induced by hypoxia 8 short-term exposure
Induced genes: vasoconstrictors

---

Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells
Phrase: in vivo exposure to hypoxia induces via a transcriptional mechanism 5-htt
Induced genes: 5-htt

---

Heat shock protein 70 and heat shock cognate protein 70 messenger ribonucleic acid induction in the brains, hearts, and livers of neonatal rats after hypoxic stress
Phrase: and liver and was further induced after hypoxia in the brain
Phrase: organs conclusion: mild hypoxia selectively induced messenger ribonucleic acid of heat
Induced genes: ribonucleic

---

Carbon-centered radicals as oxygen sensors for in vivo electron paramagnetic resonance: screening for an optimal probe among commercially available charcoals
Phrase: a simple model of hypoxia induced in mice seventeen charcoals contained
Induced genes: charcoals

---

Hypoxia-induced expression of complement receptor type 1
Phrase: cleavage of c3b thus hypoxia induces functional huvec cr1 expression
Induced genes: huvec
Induced genes: cr1

---

Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression
Phrase: our findings indicate that hypoxia stimulates carcinoma cell invasiveness by upregulating
Induced genes: upregulating

---

Introducing fluorine-18 fluoromisonidazole positron emission tomography for the localisation and quantification of pig liver hypoxia
Phrase: dynamic pet scanning hypoxia was induced by segmental arterial hepatic occlusion
Inducers of gene: segmental

---

Role of adenosine in regulating glucose uptake during contractions and hypoxia in rat skeletal muscle
Phrase: the sciatic nerve hypoxia was induced by reducing perfusate haematocrit from
Phrase: the mechanism by which hypoxia stimulates muscle glucose uptake is at
Induced genes: uptake
Inducers of gene: perfusate
Inducers of gene: haematocrit

---

aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia
Phrase: although ahif is not further induced by hypoxia in nonpapillary disease
Induced genes: ahif

---

Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase
Phrase: expression of pd-ecgf/tp prevents apoptosis induced by hypoxia kb/tp cells transfected
Phrase: can confer resistance to apoptosis induced by hypoxia and the degradation
Induced genes: pd-ecgf/tp

---

The effect of the ETA receptor antagonist
Phrase: the development of pulmonary hypertension induced by chronic hypoxia in the
Phrase: rv/lv+s and the percentage del induced by chronic hypoxia and significantly
Induced genes: hypertension
Induced genes: rv/lv+s
Induced genes: del

---

Effects of hypoxia induced by Na2S2O4 on intracellular calcium and resting potential of mouse glomus cells
Phrase: effects of hypoxia induced by na2s2o4 on intracellular calcium
Phrase: eca was 137+/-074 mv hypoxia induced by na2s2o4 1 mm reduced
Inducers of gene: na2s2o4
Inducers of gene: na2s2o4

---

Selective neurodegeneration induced in rotation-mediated aggregate cell cultures by a transient switch to stationary culture conditions: a potential model to study ischemia-related pathogenic mechanisms
Phrase: content ischemia for 2 h induced significant neuronal cell death hypoxia
Inducers of gene: h

---

Acute response of the lung mechanics of the rabbit to hypoxia
Phrase: in total lung elastance el induced by hypoxia n = 7
Phrase: in rl and el respectively induced by hypoxia compared with that
Phrase: calculated the pirr and pire induced by hypoxia and by histamine
Induced genes: elastance
Induced genes: pirr
Induced genes: pire

---

Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain
Phrase: ohio 44106 usa brain hypoxia induces an increase in brain vascularity
Phrase: 7-21 days vegf protein expression induced by hypoxia was bimodal initially
Induced genes: vascularity
Induced genes: 7-21

---

Propane-associated autoerotic fatalities
Phrase: practice in which hypoxia is induced by propane inhalation unlike the
Inducers of gene: propane

---

Ventilatory responses to hypercapnia and hypoxia after 6 h passive hyperventilation in humans
Phrase: 1 acute exposure to hypoxia stimulates ventilation and induces hypocapnia long-term
Phrase: to hypoxia stimulates ventilation and induces hypocapnia long-term exposure to hypoxia
Induced genes: ventilation
Induced genes: hypocapnia
Induced genes: hypocapnia
Induced genes: hypoxia
Inducers of gene: ventilation

---

Role of interleukin-8 in tumor growth and metastasis of human melanoma
Phrase: uvb il-8 can also be upregulated by hypoxia conditions suggesting that
Induced genes: uvb
Induced genes: il-8

---

Cold-induced apoptosis in cultured hepatocytes and liver endothelial cells: mediation by reactive oxygen species
Phrase: period this cold-induced apoptosis was inhibited by hypoxia by an array
Repressed genes: cold-induced

---

Effect of hypoxia on the hematopoietic and immune modulator preprotachykinin-I
Phrase: formation to nonhypoxic levels hypoxia induced ppt-i gene expression at 24
Induced genes: ppt-i

---

Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis
Phrase: is suppressed in normoxia and stimulated in hypoxia to test the
Inducers of gene: normoxia

---

Hypoxia stimulates the synthesis of cytochrome P450-derived inflammatory eicosanoids in rabbit corneal epithelium
Phrase: dec;2873:903-10 hypoxia stimulates the synthesis of cytochrome p450-derived
Phrase: synthesis hypoxia greatly and selectively stimulated the synthesis of 12r-hete 7-fold
Induced genes: p450-derived
Induced genes: 12r-hete
Induced genes: 7-fold

---

[Effects of hypoxia and anisodamine on products of TXA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells]
Phrase: antagonized the effect of hypoxia induced pulmonary vasoconstriction
Induced genes: vasoconstriction

---

Hypoxia induces p53 accumulation in the S-phase and accumulation of hypophosphorylated retinoblastoma protein in all cell cycle phases of human melanoma cells
Phrase: dec;7812:1547-58 hypoxia induces p53 accumulation in the s-phase
Phrase: during hypoxia because p53 was induced in a cell cycle-specific manner
Induced genes: p53
Induced genes: cycle-specific

---

Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
Phrase: vegfr-1 but not vegfr-2 was induced by hypoxia in endothelial cells
Induced genes: vegfr-1
Induced genes: vegfr-2

---

[The effect of an extract of Baikal skullcap
Phrase: the brain mitochondria in hypoxia inhibits restriction of succinate dependent energy
Repressed genes: succinate
Repressed genes: energy

---

Response of EP and cochlear blood flow to angiotensin II during hypoxic condition
Phrase: cochlea hypoxia 10 min was induced by inspiring a mixture gas
Inducers of gene: inspiring
Inducers of gene: gas

---

Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells
Phrase: we report here that hypoxia induces tsp-1 gene and protein expression
Induced genes: tsp-1

---

Endothelial cell hypoxic stress proteins
Phrase: haps by hypoxia is not inhibited by carbon monoxide subcellular fractionation
Repressors of gene: monoxide

---

Hypoxia induces apoptosis in human neuroblastoma SK-N-MC cells by caspase activation accompanying cytochrome c release from mitochondria
Phrase: 13;4391-2:168-72 hypoxia induces apoptosis in human neuroblastoma sk-n-mc
Phrase: mechanism of apoptotic cell death induced by hypoxia very low oxygen
Induced genes: sk-n-mc

---

Developmental changes of gene expression in heme metabolic enzymes in rat placenta
Phrase: while ho-1 mrna significantly decreased induced acute fetal hypoxia resulted in
Inducers of gene: ho-1

---

Effects of hypoxia on energy state and pH in resting pulmonary and femoral arterial smooth muscles
Phrase: arteries reoxygenation reversed the changes induced by hypoxia these results suggest
Induced genes: reoxygenation

---

A maturational shift in pulmonary K
Phrase: 4-ap-sensitive k+ currents were partially inhibited by exposure to acute hypoxia
Repressed genes: 4-ap-sensitive
Repressed genes: k+
Repressed genes: currents

---

Control of gill ventilation and air-breathing in the bowfin amia calva
Phrase: exhalation followed by inhalation are stimulated by aquatic or aerial hypoxia
Induced genes: exhalation

---

Hypoxia inhibits cold-induced huddling in rat pups
Phrase: sep;1133:213-22 hypoxia inhibits cold-induced huddling in rat pups
Repressed genes: cold-induced
Repressed genes: huddling
Repressed genes: pups

---

Cellular mechanisms by which adenosine induces vasodilatation in rat skeletal muscle: significance for systemic hypoxia
Phrase: reduced the increase in fvc induced by hypoxia or adenosine as
Phrase: the view that muscle vasodilatation induced by systemic hypoxia and infused
Phrase: reduced the increase in fvc induced by hypoxia preferentially affecting the
Induced genes: fvc
Induced genes: vasodilatation
Induced genes: fvc

---

Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors
Phrase: both the increase in fvc induced by hypoxia and that induced
Phrase: induced by hypoxia and that induced by adenosine; the control responses
Phrase: on the increase in fvc induced by hypoxia 4 in these
Phrase: adenosine released during systemic hypoxia induces dilatation only by acting on
Induced genes: fvc
Induced genes: fvc
Induced genes: dilatation
Inducers of gene: adenosine;

---

Stimulation of plasminogen activator inhibitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen
Phrase: mrna levels suggesting that hypoxia stimulates pai-1 expression via a pathway
Induced genes: pai-1

---

Effects of ions on adenosine binding and enzyme activity of purified S-adenosylhomocysteine hydrolase from bovine kidney
Phrase: that sah-sensitive transmethylation reactions are inhibited during renal hypoxia when intracellular
Repressors of gene: sah-sensitive
Repressors of gene: transmethylation
Repressors of gene: reactions

---

Gene expression of insulin-like growth factor-I, its receptor and binding proteins in retina under hypoxic conditions
Phrase: hybridization rnase protection assay hypoxia induced a significant increase in retinal
Induced genes: retinal

---

Changes by short-term hypoxia in the membrane properties of pyramidal cells and the levels of purine and pyrimidine nucleotides in slices of rat neocortex
Phrase: periods of hypoxia 5 min induced reproducible depolarizations which were concentration-dependently
Induced genes: depolarizations
Induced genes: concentration-dependently

---

Increased kidney xanthine oxidoreductase activity in salt-induced experimental hypertension
Phrase: to urate because xor is induced by hypoxia we assessed kidney
Induced genes: urate
Induced genes: xor

---

Intracellular sodium and calcium homeostasis during hypoxia in dopamine neurons of rat substantia nigra pars compacta
Phrase: microfluorometry transient hypoxia 3-5 min induced an outward current 1187 +/-
Phrase: that the rise in [na+]i induced by short-lasting hypoxia is not
Induced genes: outward
Induced genes: [na+]i

---

Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats
Phrase: in neuropeptide y and indolamines induced by long-term hypoxia in rats
Phrase: cedex 08 france long-term hypoxia induces changes in neuropeptide-y-like immunoreactivity npy-li
Induced genes: neuropeptide
Induced genes: y
Induced genes: indolamines
Induced genes: neuropeptide-y-like
Induced genes: npy-li

---

[Differences between effects of hypoxia on rabbit aorta and pulmonary artery]
Phrase: hypoxia to the same extent induced aorta relaxation these results indicate
Induced genes: aorta

---

Hypoxic induction of vascular endothelial growth factor
Phrase: tissues including brain since hypoxia induces vegf mrna in astroglial cultures
Induced genes: astroglial

---

Inhibition of major cationic inward currents prevents spreading depression-like hypoxic depolarization in rat hippocampal tissue slices
Phrase: current-clamped ca1 pyramidal cells hypoxia induced a rapid near-complete depolarization and
Induced genes: near-complete
Induced genes: depolarization

---

[Studies on mechanism of the inhibition of Ca2
Phrase: inhibition of ca2+/cam pkii activity induced by hypoxia in rat hippocampal
Phrase: the inhibition of enzyme activity induced by hypoxia may result from
Phrase: inhibition of the enzyme activity induced by either hypoxia or excess
Phrase: ketamine suggesting that the hypoxia induced inhibition of the enzyme activity
Induced genes: ca2+/cam
Induced genes: pkii

---

[Norepinephrine regulation of T-lymphocyte proliferation of rat during acute hypoxia]
Phrase: for 24 h of hypoxia inhibited t-lymphocyte proliferation by 41% 7
Phrase: these findings suggest that hypoxia inhibits t-lymphocyte proliferation probably through an
Repressed genes: t-lymphocyte
Repressed genes: 41%
Repressed genes: t-lymphocyte

---

[Role of endogenous endothelins in renal injury in burnt rats]
Phrase: tissue hypoxia which in turn induced atp depletion and lipoperoxidation damage
Induced genes: depletion
Induced genes: lipoperoxidation

---

Pentoxifylline inhibits hypoxia-induced upregulation of tumor cell tissue factor and vascular endothelial growth factor
Phrase: normoxic and hypoxic cells hypoxia induced a slight 5% but not
Induced genes: 5%

---

Mitochondrial calcium transporting pathways during hypoxia and reoxygenation in single rat cardiomyocytes
Phrase: [ca2+]c following atp-depletion rigor contracture induced by hypoxia in isolated cardiomyocytes
Phrase: pathways involved in the hypoxia induced changes in [ca2+]m by using
Induced genes: [ca2+]c
Induced genes: atp-depletion
Induced genes: rigor
Induced genes: contracture
Induced genes: [ca2+]m

---

Role of PECAM-1 in the adherence of PMN to hypoxic endothelial cells
Phrase: la paix namur belgium hypoxia induces an increase in pmn adherence
Induced genes: pmn
Induced genes: adherence

---

Functional regulation of human trophoblast differentiation
Phrase: hypoxia term villous cytotrophoblasts are stimulated by egf egf-ii igfbp-1 alpha1beta1
Phrase: hypoxia term villous cytotrophoblasts are stimulated to form a syncytium by
Induced genes: syncytium
Inducers of gene: egf-ii
Inducers of gene: igfbp-1
Inducers of gene: alpha1beta1

---

Cardiovascular function and brain metabolites in normal weight and intrauterine growth restricted newborn piglets--effect of mild hypoxia
Phrase: mild hypoxic hypoxia which was induced by lowering the fio2 from
Inducers of gene: lowering
Inducers of gene: fio2

---

Effects of intracellular N
Phrase: transduction pathway through which hypoxia induces vasoconstriction remains unclear we hypothesized
Phrase: the decrease in k+ current induced by hypoxia is a key
Induced genes: vasoconstriction
Induced genes: k+

---

[Shifts in the constant potential in the structures of the rat brain in focal ischemia and systemic hypoxia]
Phrase: artery mca and systemic hypoxia induced by breathing with 08% carbon
Phrase: the penumbra zone during hypoxia induced by one-hour respiration with 08%
Inducers of gene: 08%
Inducers of gene: one-hour
Inducers of gene: respiration
Inducers of gene: 08%

---

Mechanism of hypoxic preconditioning in guinea pig papillary muscles
Phrase: erp were determined hypoxia was induced by superfusion with 100% n2
Phrase: sustained hypoxia/reoxygenation results: long hypoxia induced a similar depression of df
Induced genes: depression
Inducers of gene: superfusion
Inducers of gene: 100%
Inducers of gene: n2

---

Hypoxic pulmonary vasoconstriction in pigs: role of endothelin-1, prostanoids and ATP-dependent potassium channels
Phrase: in spontaneously breathing pigs hypoxia induces pulmonary vasoconstriction and an increase
Induced genes: vasoconstriction

---

Does chronic hypoxia increase rat carotid body nitric oxide
Phrase: nos showed that chronic hypoxia induces an increase in nos activity
Induced genes: nos

---

Haemodynamic and metabolic changes induced by repeated episodes of hypoxia in pigs
Phrase: haemodynamic and metabolic changes induced by repeated episodes of hypoxia
Induced genes: haemodynamic

---

[Protective effect of magnesium on ionic channels in guinea pig ventricular myocytes during hypoxia]
Phrase: abbreviation during hypoxia was markedly inhibited in presence of 10 mmol/l
Repressed genes: mmol/l

---

Lactate, lactate
Phrase: we conclude that fetal hypoxia induces fetal ca production as well
Induced genes: ca

---

[NO-Dependent mechanisms of adaptation to hypoxia]
Phrase: demonstrate that 1 acute hypoxia induces no hyperproduction in the brain
Induced genes: hyperproduction

---

Neuromodulators and hypoxic hypothermia in the rat
Phrase: are involved in the hypometabolism induced by hypoxia in the rat
Induced genes: hypometabolism

---

Treatment of pulmonary hypertension and hypoxia due to oleic acid induced lung injury with intratracheal prostaglandin E1 during partial liquid ventilation
Phrase: hypoxia due to oleic acid induced lung injury with intratracheal prostaglandin
Induced genes: intratracheal
Induced genes: prostaglandin

---

[Mechanisms of the microcirculation during hypoxia induced by reduced local pressure]
Phrase: of the microcirculation during hypoxia induced by reduced local pressure] [article
Inducers of gene: pressure]
Inducers of gene: [article

---

Evidence that the slowing caused by acute hypoxia is modality dependent
Phrase: in both experiments hypoxia was induced with low oxygen mixtures and
Induced genes: mixtures

---

Hypoxic stimulation of the stress-activated protein kinases in pulmonary artery fibroblasts
Phrase: investigate the hypothesis that hypoxia stimulates intracellular kinase cascades we measured
Phrase: 30 h hypoxia 1% o2 stimulated strongly the stress-activated protein kinases
Induced genes: stress-activated

---

L-type Ca2
Phrase: centre glutamate release during hypoxia stimulates postsynaptic metabotropic glutamate receptors which
Induced genes: postsynaptic
Induced genes: metabotropic
Induced genes: glutamate

---

Effects of 5-day hypoxia on cardiac adrenergic neurotransmission in rats
Phrase: 91406 orsay france chronic hypoxia induces an overall sympathetic hyperactivation associated
Induced genes: sympathetic
Induced genes: hyperactivation

---

Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression
Phrase: studies have demonstrated that hypoxia stimulates expression of the c-fos gene
Induced genes: c-fos

---

Hypoxia-specific upregulation of calpain activity and gene expression in pulmonary artery endothelial cells
Phrase: the first time that hypoxia upregulates calpain activity and mrna expression
Induced genes: calpain

---

Increased vascular endothelial growth factor
Phrase: lymphocytic infiltration vegf is normally induced by hypoxia and its induction
Induced genes: infiltration

---

Modification of superoxide dismutase
Phrase: cells in culture hypoxia was induced by an incubation with nitrogen
Inducers of gene: nitrogen

---

Influence of chronic hypoxia on the contributions of non-inactivating and delayed rectifier K currents to the resting potential and tone of rat pulmonary artery smooth muscle
Phrase: in age-matched controls chronic hypoxia downregulated delayed rectifier k+ current ikv
Repressed genes: rectifier
Repressed genes: k+
Repressed genes: ikv

---

Lack of correlation between the effects of transient exposure to glutamate and those of hypoxia
Phrase: time in 13-day-old neurons hypoxia induced both apoptosis 82% and necrosis
Induced genes: 82%

---

Hypoxia induces high-mobility-group protein I
Phrase: 10;833:295-304 hypoxia induces high-mobility-group protein iy and transcription
Induced genes: high-mobility-group
Induced genes: iy

---

[Compromised tissue perfusion for defective microcirculation in children]
Phrase: acknowledged the fact that hypoxia stimulates proliferation even of osteoblasts mention
Induced genes: mention

---

Effects of nebulized nitroprusside on pulmonary and systemic hemodynamics during pulmonary hypertension in piglets
Phrase: systemic hemodynamics during pulmonary hypertension induced by hypoxia or group b
Induced genes: hemodynamics
Induced genes: hypertension

---

Cerebrolysin protects isolated cortical neurons from neurodegeneration after brief histotoxic hypoxia
Phrase: drug cerebrolysin cere against iodoacetate induced histotoxic hypoxia were investigated for
Phrase: in vitro histotoxic hypoxia was induced by incubation with 001 or
Inducers of gene: cerebrolysin
Inducers of gene: cere
Inducers of gene: iodoacetate

---

Effect of chinonin on acute hypoxic pulmonary vasoconstriction in Sprague-Dawley rats
Phrase: mpap caused by hypoxia and inhibited the action of et-1 and
Repressed genes: et-1

---

Maturational modification of hypoxic relaxation in ovine carotid and cerebral arteries: role of endothelium
Phrase: light of evidence that hypoxia inhibits cerebrovascular calcium influx and that
Repressed genes: cerebrovascular
Repressed genes: influx

---

Nitric oxide in the ventrolateral medulla regulates sympathetic responses to systemic hypoxia in pigs
Phrase: vlm significantly enhanced rsna increases induced by hypoxia and abolished the
Induced genes: vlm
Induced genes: rsna

---

Potassium channels modulate hypoxic pulmonary vasoconstriction
Phrase: ca2+-channel blocker verapamil 10-5 m inhibited the vasoconstrictor effect of hypoxia
Repressors of gene: ca2+-channel
Repressors of gene: blocker
Repressors of gene: verapamil
Repressors of gene: 10-5
Repressors of gene: m

---

[Endogenous deficiency of nitric oxide as an aggravating factor in retinal vein occlusion]
Phrase: previously dilated by systemic hypoxia induced a vasoconstriction however no arteriolar
Induced genes: vasoconstriction

---

Hypoxia evokes catecholamine secretion from rat pheochromocytoma PC-12 cells
Phrase: observed hypoxia po2 11 mmhg stimulated secretion from pc-12 cells and
Induced genes: pc-12

---

Hypoxia induced by Na2S2O4 increases [Na
Phrase: 29;7972:197-208 hypoxia induced by na2s2o4 increases [na+]i in
Phrase: was about -42 mv hypoxia induced by na2s2o4 1 mm po2
Phrase: on glomus membrane channels hypoxia induced a large [na+]i increase presumably
Induced genes: [na+]i
Inducers of gene: na2s2o4
Inducers of gene: [na+]i
Inducers of gene: na2s2o4
Inducers of gene: po2

---

Effects of hypoxia on pulmonary vascular contractility
Phrase: a krebs-henseleit solution hypoxia was induced by gassing the chamber with
Inducers of gene: gassing
Inducers of gene: chamber

---

Mechanisms of relaxation of coronary artery by hypoxia
Phrase: krebs-henseleit kh solution hypoxia was induced by gassing the chamber with
Inducers of gene: gassing
Inducers of gene: chamber

---

Elevated plasma endothelin-1 levels in sickle cell anemia: relationships to oxygen saturation and left ventricular hypertrophy
Phrase: in response to hypoxia which induces hypertrophy in cultured cardiac myocytes
Induced genes: cardiac

---

Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes
Phrase: we tested whether brief hypoxia induces preconditioning by augmenting mitochondrial generation
Induced genes: preconditioning
Induced genes: augmenting
Induced genes: mitochondrial

---

Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
Phrase: expression is developmentally regulated and induced by hypoxia in rat ventricular
Phrase: that adrenomedullin transcription can be induced by hypoxia and that this
Induced genes: developmentally
Induced genes: adrenomedullin

---

The influence of hypoxia and pH on aminolaevulinic acid-induced photodynamic therapy in bladder cancer cells in vitro
Phrase: that ala-induced pdt may be inhibited by hypoxia due to reduced
Repressed genes: ala-induced
Repressed genes: pdt

---

Attenuation of isocapnic hyperpnoea-induced guinea-pig bronchoconstriction by chronic hypoxia
Phrase: chronic hypoxia attenuated airway constriction induced by xanthine-xanthine oxidase the results
Inducers of gene: xanthine-xanthine

---

Ultrastructural changes in rat cornea after prolonged hypobaric hypoxia
Phrase: suggest that environmental hypobaric hypoxia induces marked alterations in the corneal
Induced genes: corneal

---

Differential effects of hypoxia on the intracellular Ca2
Phrase: has been proposed that hypoxia inhibits a k+ conductance which promotes
Phrase: of the intrapulmonary artery hypoxia induced a further reversible increase in
Repressed genes: k+
Repressed genes: conductance

---

Expression and protective effects of urocortin in cardiac myocytes
Phrase: cardiac myocytes from cell death induced by hypoxia the data suggest
Induced genes: cardiac

---

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia
Phrase: luciferase activity in hypoxia was inhibited by the addition of snp
Phrase: treatment mimics hypoxia was also inhibited by snp ic50 = 25
Phrase: factor in hypoxia was also inhibited by the no donor we
Repressors of gene: snp
Repressors of gene: snp
Repressors of gene: ic50
Repressors of gene: =

---

Modulation of junctional conductance between rat carotid body glomus cells by hypoxia, cAMP and acidity
Phrase: large variations in vm hypoxia induced by na2s2o4 1 mm or
Inducers of gene: na2s2o4

---

Hypoxic and hypoglycaemic changes of intracellular pH in cerebral cortical pyramidal neurones
Phrase: neurones transient 5 min hypoxia induced a fall of phi 712
Induced genes: phi

---

Pulmonary perfusion measured by means of electrical impedance tomography
Phrase: eit signal moreover the hypoxia induced decrease in delta zsys indicates
Induced genes: zsys

---

Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3
Phrase: massachusetts 02114 usa chronic hypoxia induces pulmonary hypertension and right ventricular
Induced genes: hypertension
Induced genes: right

---

Evidence for a role for AtMYB2 in the induction of the Arabidopsis alcohol dehydrogenase gene
Phrase: we show that atmyb2 is induced by hypoxia with kinetics compatible
Induced genes: atmyb2

---

Role of NF-kappaB-mediated interleukin-8 expression in intraocular neovascularization
Phrase: glial cells in vitro hypoxia induced nf-kappab activation and increased il-8
Phrase: these results suggest that il-8 induced by hypoxia and mediated by
Induced genes: il-8
Induced genes: il-8

---

Effects of glucose deprivation, chemical hypoxia, and simulated ischemia on Na
Phrase: glucose removal or chemical hypoxia induced by 10 mm nan3 for
Inducers of gene: nan3

---

Hypoxia
Phrase: presence of cycloheximide during hypoxia inhibited both peaks of synthesis and
Repressed genes: peaks

---

Vasorelaxant effects of SCA40
Phrase: lungs sca40 reversed the vasoconstriction induced by alveolar hypoxia it was
Induced genes: lungs
Induced genes: sca40
Induced genes: vasoconstriction

---

Mechanism of hypoxia-stimulated glucose transport in rat skeletal muscle: potential role of glycogen
Phrase: of muscle glycogen in the inhibited glucose transport response to hypoxia
Phrase: of glycogen contribute to the inhibited glucose transport response to hypoxia
Repressors of gene: glycogen
Repressors of gene: glycogen

---

Regulation of macrophage production of vascular endothelial growth factor
Phrase: macrophage production of vegf is upregulated by hypoxia and tgfbeta-1 both
Induced genes: macrophage

---

Electrophysiological and immunocytological demonstration of cell-type specific responses to hypoxia in the adult cat carotid body
Phrase: cells whose outward current was inhibited by hypoxia showed th-immunoreactivity but
Repressed genes: outward

---

Pulmonary artery remodeling differs in hypoxia- and monocrotaline-induced pulmonary hypertension
Phrase: both mct and chronic hypoxia induced right ventricular hypertrophy in separate
Phrase: in contrast to chronic hypoxia induces structural changes of muscular pulmonary
Induced genes: right
Induced genes: muscular

---

Erythropoietin: a model system for studying oxygen-dependent gene regulation
Phrase: in length hif-1 binding is induced by hypoxia as well as
Induced genes: hif-1

---

Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway
Phrase: 1;919:3300-7 hypoxia stimulates urokinase receptor expression through a
Induced genes: urokinase

---

Hypoxia and cyanide induce depolarization and catecholamine release in dispersed guinea-pig chromaffin cells
Phrase: chemical hypoxia 3 the secretions induced by cn and muscarine were
Inducers of gene: cn
Inducers of gene: muscarine

---

Composition of the cerebral white matter sterol ester fraction in severe experimental hypoxia
Phrase: sciences poznan severe hypoxia was induced in adult wistar rats by
Phrase: cholesta-35-dien cholesta-4-en-3-on 22-propyl-3 beta-hydroxy-524-cholestadien the induced severe hypoxia lead to a
Inducers of gene: cholesta-35-dien
Inducers of gene: cholesta-4-en-3-on
Inducers of gene: 22-propyl-3
Inducers of gene: beta-hydroxy-524-cholestadien

---

Effects of tetramethylpyrazine, a Chinese medicine, on plasma endothelin-1 levels during acute pulmonary hypoxia in anesthetized dogs
Phrase: the treatment of pulmonary hypertension induced by acute hypoxia through decrease
Induced genes: hypertension

---

Hypoxia increases vasodilator release from internal mammary artery and saphenous vein grafts
Phrase: by hypoxia this augmentation was inhibited by indomethacin n = 10
Repressors of gene: indomethacin
Repressors of gene: n
Repressors of gene: =

---

Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
Phrase: reported that et-1 expression was induced by both hypoxia and transition
Induced genes: et-1

---

Excitatory amino acid receptor antagonists decrease hypoxia induced increase in extracellular dopamine in striatum of newborn piglets
Phrase: acid receptor antagonists decrease hypoxia induced increase in extracellular dopamine in
Induced genes: dopamine

---

Thalamic locus mediates hypoxic inhibition of breathing in fetal sheep
Phrase: as in normal fetuses hypoxia inhibited breathing with transection rostral to
Repressed genes: transection
Repressed genes: rostral

---

Hypoxia and vascular endothelial growth factor stimulate angiogenic integrin expression in bovine retinal microvascular endothelial cells
Phrase: < 001 respectively similarly hypoxia stimulated gene expression of integrin alphav
Phrase: these data suggest that hypoxia stimulates expression of vascular integrins alphavbeta3
Induced genes: integrin
Induced genes: alphav
Induced genes: alphavbeta3

---

Effect of propentofylline on free radical generation during cerebral hypoxia in the newborn piglet
Phrase: the same conditions hypoxia was induced through a decrease in fio2
Phrase: following hypoxia and were subsequently inhibited by propentofylline the administration of
Induced genes: fio2
Repressors of gene: propentofylline

---

Trichinella spiralis: vascular endothelial growth factor is up-regulated within the nurse cell during the early phase of its formation
Phrase: we propose that hypoxia is induced by t spiralis within the
Inducers of gene: t
Inducers of gene: spiralis

---

Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia
Phrase: had no effect on those induced by hypoxia 3 the a2a
Phrase: reduced the increase in corcf induced by hypoxia 5 we propose
Induced genes: corcf

---

Alpha 2-adrenoceptor-mediated antisecretory effect of hypoxia in conscious rats
Phrase: results indicate that acute hypoxia stimulated the adrenergic response from the
Induced genes: adrenergic

---

Regulation of proliferation-survival decisions during tumor cell hypoxia
Phrase: cycle and p53 expression hypoxia induces g0/g1 arrest in primary fibroblasts
Phrase: response to hypoxia-induced acidosis but downregulated during hypoxia without acidosis hypoxia
Repressors of gene: hypoxia-induced
Repressors of gene: hypoxia-induced
Repressors of gene: acidosis
Repressors of gene: acidosis

---

Naked cDNA encoding secreted proteins for intra-arterial and intramuscular gene transfer
Phrase: to high-affinity receptors that are upregulated by hypoxia thus the success
Induced genes: high-affinity

---

Chemical hypoxia triggers apoptosis of cultured neonatal rat cardiac myocytes: modulation by calcium-regulated proteases and protein kinases
Phrase: showed here that chemical hypoxia induced by 1 mm azide triggered
Inducers of gene: azide

---

Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1
Phrase: hypoxia study design: anemia was induced in near-term ovine fetuses by
Induced genes: near-term
Induced genes: ovine
Induced genes: fetuses

---

Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia
Phrase: action on cam expression hypoxia induced a time-dependent increase in the
Phrase: to the enhanced icam mrna induced by il-1beta during hypoxia however
Induced genes: icam

---

Potential interest of anti-ischemic agents for limiting cyclosporin A nephrotoxicity
Phrase: in experimental models of hypoxia induced by cyclosporin a: it restores
Inducers of gene: a:

---

Identification of a human VPF
Phrase: tumor areas and hypoxia potently induces vpf/vegf expression in several tumor
Phrase: thus increased vpf/vegf mrna stability induced by hypoxia is mediated at
Induced genes: vpf/vegf
Induced genes: vpf/vegf

---

Influence of acidosis on cardiotonic effects of milrinone
Phrase: pbf were measured acidosis was induced by transient hypoxia and maintained
Induced genes: pbf
Induced genes: acidosis

---

The endothelial receptor tyrosine kinase tie-1 is upregulated by hypoxia and vascular endothelial growth factor
Phrase: receptor tyrosine kinase tie-1 is upregulated by hypoxia and vascular endothelial
Induced genes: tie-1

---

Hypoxia-induced free iron release in the red cells of newborn infants
Phrase: iron concentration in conclusion hypoxia induces intra-erythrocyte free iron release and
Induced genes: intra-erythrocyte
Induced genes: iron

---

Inhibitory effects of hypoxia and adenosine on N-methyl-D-aspartate-induced pial arteriolar dilation in piglets
Phrase: nmda-induced cerebral arteriolar dilation is inhibited by hypoxia alone and by
Repressed genes: nmda-induced
Repressed genes: dilation

---

Accuracy of noninvasive oxyhemoglobin saturation, end-tidal carbon dioxide concentration, and blood pressure monitoring during experimentally induced hypoxemia, hypotension, or hypertension in anesthetized dogs
Phrase: petco2 were determined during rapidly induced plateaus of hypoxia decreased fractional
Inducers of gene: petco2

---

Effect of inhaled nitric oxide on the hypoxic pulmonary vasoconstrictor response in anaesthetised calves
Phrase: and xylazine alveolar hypoxia was induced by means of the inhalation
Phrase: oxide significantly attenuated the hypoxia induced pulmonary hypertension the effect ceased
Phrase: oxide fully abolished the hypoxia induced pulmonary hypertension mean pulmonary artery
Induced genes: hypertension
Induced genes: hypertension

---

Hypoxia inhibits cyclic nucleotide-stimulated epithelial ion transport: role for nucleotide cyclases as oxygen sensors
Phrase: feb;2842:568-75 hypoxia inhibits cyclic nucleotide-stimulated epithelial ion transport:
Phrase: the impact of hypoxia on stimulated epithelial ion transport function t84
Phrase: 72 h and assessed for stimulated ion transport hypoxia evoked a
Induced genes: t84
Inducers of gene: h
Repressed genes: nucleotide-stimulated
Repressed genes: transport:

---

Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1
Phrase: 1:l212-9 hypoxia induces type ii nos gene expression
Induced genes: nos

---

Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells
Phrase: and radioimmunoassay showed that hypoxia stimulated the accumulation of adm mrna
Induced genes: adm

---

Effects of hypoxia and metabolic inhibition on increases in intracellular Ca2
Phrase: from the sarcoplasmic reticulum are inhibited in hypoxia and metabolic inhibition
Repressors of gene: sarcoplasmic

---

Identification of genes differentially expressed by hypoxia in hepatocellular carcinoma cells
Phrase: sapiens oscillin moreover novel genes induced by hypoxia represent partial sequences
Induced genes: sapiens
Induced genes: oscillin

---

Acute and chronic increases in excitability in rat hippocampal slices after perinatal hypoxia In vivo
Phrase: have previously shown that hypoxia induces both acute and chronic epileptogenic
Phrase: dependent global hypoxia 3-4% o2 induces seizure activity in the developing
Phrase: adult rats with prior seizures induced by hypoxia at p10 show
Induced genes: epileptogenic
Induced genes: seizure
Induced genes: seizures

---

Glucose intolerance induced by oligemic brain hypoxia: the effect of terguride
Phrase: wistar strain glucose intolerance was induced by oligemic brain hypoxia 4
Phrase: trans-dihydro-lisuride was tested brain hypoxia induced glucose intolerance in both strains
Phrase: normotensive female where brain hypoxia induced hyperglycaemia the second series of
Induced genes: intolerance
Induced genes: intolerance
Induced genes: hyperglycaemia

---

Effects of chronic hypoxia on Ca2
Phrase: in contrast chronic hypoxia significantly inhibited 5-ht-induced contractions and decreased the
Repressed genes: 5-ht-induced
Repressed genes: contractions

---

Glycine protection against hypoxic injury in isolated rat proximal tubules: the role of proteases
Phrase: detected calpain activity was not inhibited directly by glycine conclusions: hypoxia
Repressors of gene: calpain

---

Inhibition of 3-hydroxy-3-methylglutaryl
Phrase: boston massachusetts 02115 usa hypoxia induces vasoconstriction in part by down-regulating
Induced genes: vasoconstriction

---

[Glutathione, a biochemical indicator for different types of cellular stress
Phrase: hypoxia of 10 minutes was induced after beheading there was determined
Phrase: the gsh depletion in the induced hypoxia by our experiment might
Induced genes: beheading
Inducers of gene: gsh
Inducers of gene: depletion

---

Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells
Phrase: the pathophysiology of vascular disorders induced by hypoxia we have recently
Induced genes: pathophysiology

---

Exposure to chronic hypoxia induces qualitative changes of collagen in the walls of peripheral pulmonary arteries
Phrase: exposure to chronic hypoxia induces qualitative changes of collagen in
Induced genes: qualitative

---

Chronic hypoxia induces proliferation of cultured mesangial cells: role of calcium and protein kinase C
Phrase: chronic hypoxia induces proliferation of cultured mesangial cells:
Phrase: with respective normoxic controls hypoxia induced a biphasic activation of pkc
Phrase: vitro evidence that chronic hypoxia induces proliferation of cultured glomerular mesangial
Induced genes: mesangial
Induced genes: glomerular
Induced genes: mesangial

---

Effect of dorzolamide on corneal endothelial function in normal human eyes
Phrase: eye steady state thickness swelling induced by hypoxia and corneal autofluorescence
Induced genes: eye
Induced genes: thickness
Induced genes: swelling

---

Hydrogen peroxide derived from hepatocytes induces sinusoidal endothelial cell apoptosis in perfused hypoxic rat liver
Phrase: in secs conclusions: low-flow hypoxia induces h2o2 production in hepatocytes and
Induced genes: hepatocytes

---

Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia
Phrase: old wistar rats the depression induced by hypoxia 14 min was
Induced genes: depression

---

A model of hypoxia-induced necrotizing enterocolitis: the role of distension
Phrase: group 5 control hypoxia was induced by placing the rat pups
Inducers of gene: placing
Inducers of gene: pups

---

Inhaled vancomycin-induced allergic reaction in decontamination of respiratory tracts for allogeneic bone marrow transplantation
Phrase: that vancomycin hydrochloride vcm repeatedly induced dyspnea fever hypoxia eosinophilia and
Inducers of gene: vancomycin
Inducers of gene: hydrochloride
Inducers of gene: vcm
Inducers of gene: repeatedly

---

Red nucleus inhibits breathing during hypoxia in neonates
Phrase: red nucleus inhibits breathing during hypoxia in neonates
Repressors of gene: red

---

Hypoxia inhibits gene expression of voltage-gated K
Phrase: 1;1009:2347-53 hypoxia inhibits gene expression of voltage-gated k+
Phrase: vasomotor tone acute hypoxia selectively inhibits kv channels depolarizes pasmc raises
Repressed genes: voltage-gated
Repressed genes: k+
Repressed genes: depolarizes
Repressed genes: pasmc

---

[Nitric oxide as a factor in the antihypoxic effect of adaptation to physical loading]
Phrase: no production doubled acute hypoxia induced a biphase change in tissue
Induced genes: biphase

---

Hypoxia-induced inhibition of calcium channels in guinea-pig taenia caeci smooth muscle cells
Phrase: at -20 mv hypoxia reversibly inhibited the spontaneous transient outward currents
Phrase: results show that hypoxia reversibly inhibits ica and secondarily suppresses ikca
Repressed genes: outward
Repressed genes: currents
Repressed genes: ica
Repressed genes: secondarily
Repressed genes: ikca

---

Interaction between BTBR and C57BL
Phrase: the hyperinsulinemic male mice hypoxia stimulates glucose transport through an insulin-independent
Phrase: the insulin-resistant male mice hypoxia induced glucose transport as effectively as
Induced genes: insulin-independent

---

Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation
Phrase: teratogenicity is initiated by pharmacologically induced embryonic hypoxia a genetic susceptibility
Inducers of gene: teratogenicity
Inducers of gene: pharmacologically

---

Attenuated response of renal mechanoreceptors to volume expansion in chronically hypoxic rats
Phrase: in these animals hypoxia was induced by placing wistar rats in
Inducers of gene: placing

---

Long-term contact lens wear induces a corneal degeneration with microdot deposits in the corneal stroma
Phrase: assume the deposits to be induced by chronic hypoxia the condition
Induced genes: assume
Induced genes: deposits

---

Acute and long-lasting effects of neonatal hypoxia on
Phrase: in rats exposed to hypoxia induced by 93% n2/65% o2 exposure
Inducers of gene: 93%
Inducers of gene: n2/65%
Inducers of gene: o2

---

Hypoxia regulates xanthine dehydrogenase activity at pre- and posttranslational levels
Phrase: exposure to hypoxia 24-48 h induced an increase in xo-xdh mrna
Induced genes: xo-xdh

---

[Endothelin and ATP-sensitive potassium channel mediate electrophysiological changes induced by hypoxia in rabbit sinoatrial node]
Phrase: potassium channel mediate electrophysiological changes induced by hypoxia in rabbit sinoatrial
Phrase: and the decrease in apd induced by hypoxia may be attributed
Induced genes: potassium
Induced genes: channel
Induced genes: electrophysiological
Induced genes: apd

---

Tamoxifen induces hypoxia in MCF-7 xenografts
Phrase: 15;5722:5155-61 tamoxifen induces hypoxia in mcf-7 xenografts
Inducers of gene: 15;5722:5155-61

---

Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia
Phrase: of these nuclei hypoxia also induced fos expression albeit generally less
Induced genes: fos

---

Vanadate stimulation of 2-deoxyglucose transport is not mediated by PI 3-kinase in human skeletal muscle
Phrase: in mammalian skeletal muscle is stimulated by insulin hypoxia and tyrosine
Phrase: vanadate with insulin and hypoxia stimulated 2-deoxyglucose transport 2-dog we also
Phrase: hypoxia were additive with insulin stimulated glucose transport the effect of
Phrase: but not vanadate or hypoxia stimulated 2-dog transport moreover pi 3-kinase
Induced genes: 2-deoxyglucose
Induced genes: 2-dog
Induced genes: 2-dog
Induced genes: 3-kinase

---

Effects of active vasoconstriction and total flow on perfusion distribution in the rabbit lung
Phrase: respective influences of active vasoconstriction induced by alveolar hypoxia and pulmonary
Induced genes: vasoconstriction

---

Hypoxia stimulates human preproendothelin-1 promoter activity in transgenic mice
Phrase: 1:l848-55 hypoxia stimulates human preproendothelin-1 promoter activity in
Induced genes: preproendothelin-1

---

Impairment of cation transport in A549 cells and rat alveolar epithelial cells by hypoxia
Phrase: these results indicate that hypoxia inhibits apical na entry pathways and
Repressed genes: apical

---

Interaction between tetanus long-term potentiation and hypoxia-induced potentiation in the rat hippocampus
Phrase: high magnesium concentration hypoxia was induced by replacing the 5% co2-95%
Phrase: independent of preexisting synaptic levels induced by high-frequency stimulation hypoxia produced
Phrase: preserved the magnitude of tetanus-ltp induced 20 min after hypoxia 15
Induced genes: preexisting
Induced genes: synaptic
Inducers of gene: 5%
Inducers of gene: co2-95%
Inducers of gene: preserved
Inducers of gene: tetanus-ltp

---

Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins
Phrase: involved remain unknown hypoxia was induced in newborn piglets and changes
Induced genes: newborn
Induced genes: piglets

---

Effect of glycine on prelethal and postlethal increases in calpain activity in rat renal proximal tubules
Phrase: prelethal increases in calpain activity stimulated by hypoxia and ionomycin treatment
Induced genes: prelethal
Induced genes: calpain

---

Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet
Phrase: the same conditions hypoxia was induced with a lowered fio2 and
Phrase: corresponding to alkoxyl radicals were induced by hypoxia but were inhibited
Phrase: induced by hypoxia but were inhibited by pretreatment with nnla before
Phrase: before inducing hypoxia nnla also inhibited hypoxia-induced generation of conjugated dienes
Induced genes: lowered
Induced genes: fio2
Induced genes: alkoxyl
Repressed genes: hypoxia-induced
Repressed genes: conjugated
Repressors of gene: nnla

---

Nitric oxide attenuates reoxygenation-induced ICAM-1 expression in coronary microvascular endothelium: role of NFkappaB
Phrase: cmec primary cultures is not induced by hypoxia alone but appears
Induced genes: cmec

---

Hypoxia stimulates ecNOS mRNA expression by differentiated human trophoblasts
Phrase: 26;828:180-7 hypoxia stimulates ecnos mrna expression by differentiated
Induced genes: ecnos

---

Effect of hypoxia and dopamine on arachidonic acid metabolism in superior cervical ganglion
Phrase: these results indicate that hypoxia inhibits selectively aa incorporation on the
Repressed genes: aa

---

Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
Phrase: 16 oncoproteins in vitro hypoxia stimulated both p53 induction and apoptosis
Phrase: substantially less sensitive to apoptosis induced by hypoxia indicating that these
Induced genes: p53

---

Spontaneous induction of nitric oxide- and prostaglandin E2-release by hypoxic astroglial cells is modulated by interleukin 1 beta
Phrase: il1 beta in conclusion hypoxia stimulates cytokine network in astroglial cells
Induced genes: astroglial

---

Acute hypoxia upregulates NOS gene expression in rats
Phrase: acute hypoxia upregulates nos gene expression in rats
Phrase: livers nos-iii mrna levels were upregulated by hypoxia in all tissues
Induced genes: nos
Induced genes: nos-iii

---

Age-related changes in axonal transport
Phrase: inhibition of glycolysis and hypoxia induced a greater at deceleration in
Induced genes: deceleration

---

Mechanism of hypoxic K loss in rabbit ventricle
Phrase: pathways promoting na influx were inhibited net k loss during hypoxia
Repressors of gene: influx

---

Blood pressure and heart rate changes during apnoea testing with or without CO2 insufflation
Phrase: serious adverse effects hypoxia newly induced cardiac arrhythmia cardiac asystole an
Induced genes: cardiac
Induced genes: arrhythmia
Induced genes: cardiac
Induced genes: asystole

---

Hypoxia-induced Fos expression in neurons projecting to the pressor region in the rostral ventrolateral medulla
Phrase: were subjected to moderate hypoxia induced by breathing 10% o2 in
Inducers of gene: 10%
Inducers of gene: o2

---

Adenosine A1 receptor activation preferentially protects cultured cerebellar neurons versus astrocytes against hypoxia-induced death
Phrase: cpa reduced neuronal ldh release induced by a combination of hypoxia
Phrase: against cellular damage of death induced specifically by hypoxia as opposed
Induced genes: cpa
Induced genes: ldh

---

Changes of superoxide dismutase
Phrase: line in culture hypoxia was induced by an incubation with nitrogen
Inducers of gene: nitrogen

---

Rapid and specific efflux of glutathione before hepatocyte injury induced by hypoxia
Phrase: of glutathione before hepatocyte injury induced by hypoxia khan
Phrase: reductant greatly increased the hypoxia induced gsh efflux as well as
Phrase: efflux and membrane lysis hypoxia induced gsh efflux and cytotoxicity were
Induced genes: hepatocyte
Induced genes: gsh
Induced genes: efflux
Induced genes: gsh
Induced genes: efflux

---

Prominent role of intracellular Ca2
Phrase: bubbled with 95%o2/5%co2 hypoxia was induced by bubbling phenylephrine pe 1
Phrase: preparation 4 when hypoxia was induced in the presence of thaps
Induced genes: thaps
Inducers of gene: bubbling
Inducers of gene: phenylephrine

---

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
Phrase: on p53 and p53 is induced by hypoxia in cardiac myocytes
Induced genes: p53
Induced genes: p53

---

Hypoxia stimulates proximal tubular cell matrix production via a TGF-beta1-independent mechanism
Phrase: sep;523:637-47 hypoxia stimulates proximal tubular cell matrix production
Phrase: produced by pte although hypoxia stimulated tgf-beta production 2- to 3-fold
Phrase: not mimic hypoxia as it stimulated mmp-2 activity and increased the
Induced genes: 2-

---

Hypoxia downregulates continuous and interleukin-1-induced expression of human chorionic gonadotropin in choriocarcinoma cells
Phrase: sep;187:597-604 hypoxia downregulates continuous and interleukin-1-induced expression of
Repressed genes: interleukin-1-induced

---

Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway
Phrase: 12;27237:23435-9 hypoxia induces c-fos transcription via a mitogen-activated
Phrase: oxygen intermediate level by hypoxia induces c-fos via the mapk pathway
Induced genes: c-fos
Induced genes: c-fos
Induced genes: mapk

---

Hypoxia-inducible factor 1alpha
Phrase: strongly suggest that the hypoxia induced changes in hif-1alpha stability and
Induced genes: hif-1alpha

---

Peripheral chemosensitivity and central integration: neuroplasticity of catecholaminergic cells under hypoxia
Phrase: body chemoafferents early postnatal hypoxia induced long-term neurochemical changes in carotid
Induced genes: neurochemical

---

Cyclophilins are induced by hypoxia and heat stress in myogenic cells
Phrase: cyclophilins are induced by hypoxia and heat stress
Induced genes: cyclophilins

---

Erythropoietin production in healthy volunteers subjected to controlled hypobaric hypoxia: further evidence against a role for adenosine
Phrase: present study erythropoietin production was stimulated by hypobaric hypoxia by subjecting
Induced genes: erythropoietin

---

Renal function of substance P in rats chronically exposed to hypoxia
Phrase: level sl methods: hypoxia was induced by placing female wistar rats
Inducers of gene: placing

---

Pulmonary vasoreactivity to serotonin during hypoxia is modulated by ATP-sensitive potassium channels
Phrase: compliance whereas during hypoxia cromakalim inhibited the potentiated effect of serotonin
Repressed genes: serotonin

---

Effect of 2,4-dinitrophenol on the hypometabolic response to hypoxia of conscious adult rats
Phrase: drop determined by hypoxia and stimulates vo2 not dissimilarly from normoxia
Induced genes: vo2
Induced genes: dissimilarly
Induced genes: normoxia

---

Function of cell membranes in cerebral cortical tissue of newborn piglets after hypoxia and inhibition of nitric oxide synthase
Phrase: or saline infusion hypoxia was induced by lowering the fio2 to
Inducers of gene: lowering
Inducers of gene: fio2

---

Source and cause of endothelin-1 release into cerebrospinal fluid after subarachnoid hemorrhage
Phrase: after exposure to hemoglobins hypoxia inhibited et-1 release by endothelial cells
Phrase: 005 but in astrocytes hypoxia induced an increase of et-1 at
Induced genes: et-1
Repressed genes: et-1

---

Energy metabolism in liver of anoxia-tolerant turtle species
Phrase: cold hypoxia and glycolysis is inhibited additional changes suggested by 1h
Repressed genes: 1h

---

Preclinical evaluation of the fluorinated 2-nitroimidazole N-
Phrase: mrs an increase in hypoxia induced by hydralazine treatment of rif-1
Inducers of gene: hydralazine
Inducers of gene: rif-1

---

Co-transactivation of the 3
Phrase: hif-1 dna binding activity is induced in response to hypoxia in
Inducers of gene: hif-1

---

Selective changes in cell bodies and growth cones of nerve growth factor-differentiated PC12 cells induced by chemical hypoxia
Phrase: nerve growth factor-differentiated pc12 cells induced by chemical hypoxia
Induced genes: factor-differentiated

---

Cellular respiration during hypoxia
Phrase: respiration during hypoxia was also inhibited when nnn'n'-tetramethyl-p-phenylenediamine 05 mm and
Repressed genes: nnn'n'-tetramethyl-p-phenylenediamine

---

Selective inhibition of a slow-inactivating voltage-dependent K
Phrase: 20 ps k+ channel was inhibited by hypoxia exposure to hypoxia
Phrase: slow-inactivating k+ channel that is upregulated by hypoxia this channel appears
Induced genes: slow-inactivating
Induced genes: k+
Induced genes: channel
Repressed genes: k+
Repressed genes: k+
Repressed genes: channel
Repressed genes: channel

---

Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats
Phrase: rats with pulmonary hypertension ph induced by chronic hypoxia or by
Induced genes: hypertension

---

Superoxide dismutase does protect the cultured rat cardiac myocytes against hypoxia
Phrase: in membrane integrity and fluidity induced by hypoxia or hypoxia/reoxygenation could
Induced genes: fluidity

---

Relationship between membrane potential, delayed rectifier K
Phrase: hypoxia po2 20-30 mmhg; throughout inhibited the ca2+-insensitive component of the
Repressed genes: ca2+-insensitive

---

Phorbol esters stimulate muscle glucose transport by a mechanism distinct from the insulin and hypoxia pathways
Phrase: or hypoxia phorbol ester treatment induced 5- to 10-fold increases in
Phrase: which either insulin or hypoxia stimulates muscle glucose transport they also
Induced genes: 5-

---

Effect of central endogenous angiotensin II on sympathetic activation induced by hypoxia
Phrase: angiotensin ii on sympathetic activation induced by hypoxia gaudet
Phrase: system on the sympathetic activation induced by hypoxia in conscious rabbits
Induced genes: angiotensin
Induced genes: sympathetic
Induced genes: sympathetic

---

In vivo hypoxia-induced neuronal damage with an enhancement of neuronal nitric oxide synthase immunoreactivity in hippocampus
Phrase: results suggest that hypoxia alone induces enhancement of nnos protein and
Induced genes: nnos

---

Effect of hypoxia on the proliferation of retinal microvessel endothelial cells in culture
Phrase: background: to determine if hypoxia stimulates the proliferation of retinal microvessel
Phrase: hypoxia increases dna synthesis and stimulates proliferation of retinal microvessel endothelial
Induced genes: retinal
Induced genes: retinal

---

Glycine protects against hepatocyte killing by KCN or hypoxia by preventing intracellular Na
Phrase: conductance protects against hepatocyte killing induced by kcn and hypoxia by
Induced genes: conductance
Induced genes: hepatocyte

---

Single needle venovenous extracorporeal membrane oxygenation using a nonocclusive roller pump for rescue in infants and children
Phrase: treatment were hypoxia and hypoxic induced myocardial dysfunction resulting from pulmonary
Induced genes: myocardial

---

Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1
Phrase: hypoxia-ischemia but not hypoxia alone induces the expression of heme oxygenase-1
Induced genes: heme
Induced genes: oxygenase-1

---

Chronic hypoxia induces LLC-PK1 cell proliferation and dedifferentiation by the activation of protein kinase C
Phrase: chronic hypoxia induces llc-pk1 cell proliferation and dedifferentiation
Phrase: results indicate that chronic hypoxia induces both proliferation and dedifferentiation of
Induced genes: llc-pk1

---

Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung
Phrase: 1:l1167-73 hypoxia inhibits nitric oxide synthesis in isolated
Phrase: oxide synthase nos can be inhibited by hypoxia because molecular oxygen
Repressed genes: nos

---

Neurotoxicity of soluble macrophage products in vitro--influence of dexamethasone
Phrase: h while the culture was stimulated with lipopolysaccharide and hypoxia conditioned
Inducers of gene: h

---

Decreased nitric oxide production accounts for secondary arteriolar constriction after retinal branch vein occlusion
Phrase: previously dilated by systemic hypoxia induced a vasoconstriction however no arteriolar
Induced genes: vasoconstriction

---

Alterations of myocardial sympathetic innervation in response to hypoxia
Phrase: the change in uptake-1 function induced by hypoxia three sets of
Induced genes: uptake-1

---

Hyperthermia after cardiac surgery
Phrase: and hypoxia developed but protamine induced hypotension recovered after administration of
Induced genes: hypotension

---

Hypoxia induces intercellular adhesion molecule-1 on cultured human tubular cells
Phrase: jun;516:1703-9 hypoxia induces intercellular adhesion molecule-1 on cultured
Phrase: process we investigated whether hypoxia stimulates the expression of icam-1 by
Phrase: hypoxia is a stimulus that induces the synthesis and expression of
Induced genes: intercellular
Induced genes: icam-1

---

Acidic conditions ameliorate both adenosine triphosphate depletion and the development of hyperpermeability in cultured Caco-2BBe enterocytic monolayers subjected to metabolic inhibition
Phrase: chemical hypoxia at ph0 74 induced by glu-/2dog plus antimycin a
Inducers of gene: glu-/2dog
Inducers of gene: plus
Inducers of gene: antimycin

---

Effect of hypoxia on blood glucose, hormones, and insulin receptor functions in newborn calves
Phrase: it is concluded that hypoxia induced insulin resistance in these newborn
Induced genes: insulin
Induced genes: newborn

---

Developmental changes in isolated rat type I carotid body cell K
Phrase: observation arises because hypoxia selectively inhibits kca channels in cells at
Repressed genes: kca

---

Effect of acute alterations in inspired oxygen tension on methacholine induced bronchoconstriction in patients with asthma
Phrase: conclusions: acute hypoxia potentiates methacholine induced bronchoconstriction and acute hyperoxia has
Induced genes: bronchoconstriction

---

Chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary artery relaxation
Phrase: chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary
Repressed genes: postnatal
Repressed genes: maturation
Repressed genes: porcine
Repressed genes: intrapulmonary

---

Hypoxia inhibits the induction of argininosuccinate synthetase by endotoxin in lung endothelial cells
Phrase: 1:l934-8 hypoxia inhibits the induction of argininosuccinate synthetase
Phrase: have previously shown that hypoxia inhibits synthesis of l-arginine from l-citrulline
Phrase: these results indicate that hypoxia inhibits endotoxin-mediated induction of as this
Repressed genes: argininosuccinate
Repressed genes: synthetase
Repressed genes: l-arginine
Repressed genes: l-citrulline
Repressed genes: endotoxin-mediated

---

[Molecular biology of apoptosis]
Phrase: noted that necrotic cell death induced by chemical hypoxia shares at
Induced genes: necrotic

---

Differential effects of acute hypoxia and endotoxin on the secretion and expression of bone marrow interleukin-1 and interleukin-6
Phrase: newark 07103 usa hemorrhagic shock induces tissue hypoxia and has been
Inducers of gene: newark
Inducers of gene: hemorrhagic

---

Hypoxia inhibits the recombinant alpha 1C subunit of the human cardiac L-type Ca2
Phrase: 3:551-6 hypoxia inhibits the recombinant alpha 1c subunit
Phrase: ca2+ channel currents were reversibly inhibited by hypoxia po2 < 90
Repressed genes: 1c
Repressed genes: channel
Repressed genes: currents

---

Hyperoxic injury decreases alveolar epithelial cell expression of vascular endothelial growth factor
Phrase: capillary beds vegf expression is induced by hypoxia and may be
Phrase: by hypoxia and may be inhibited by hyperoxia we examined the
Induced genes: capillary
Induced genes: beds

---

Hypoxia stimulates cytokine production by villous explants from the human placenta
Phrase: may;825:1582-8 hypoxia stimulates cytokine production by villous explants
Induced genes: explants

---

Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia
Phrase: and glucose ischaemia hypoxia alone induced degeneration selectively in ca1 pyramidal
Phrase: or cnqx also prevented death induced by either hypoxia or ischaemia
Induced genes: degeneration
Induced genes: ca1
Induced genes: cnqx

---

Production of interleukin-6 induced by hypoxia linked to peripheral arterial disease
Phrase: production of interleukin-6 induced by hypoxia linked to peripheral
Induced genes: interleukin-6

---

Pulmonary function values in Friesian and double-muscled calves during acute poikilocapnic hypoxia
Phrase: hf and bwb calves hypoxia induced a significant increase in tidal
Induced genes: tidal

---

[Erythropoietin gene: regulation and therapeutic concern]
Phrase: post transcriptional levels the hypoxia induced factor hif-i activates the transcription
Induced genes: hif-i

---

Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways
Phrase: or bcl-xl prevents cell death induced by withdrawal of oxygen hypoxia
Phrase: microscopy we show that hypoxia induces both necrosis and apoptosis overexpression
Induced genes: bcl-xl

---

Cerebral metabolic consequences of neonatal pathologies in the immature rat
Phrase: measured by autoradiography hypoxia was induced by breathing a 7% n2/93%
Phrase: bilirubin/albumin solution hypoxia and seizures induced a general increase in cerebral
Inducers of gene: 7%
Inducers of gene: n2/93%

---

Astrocytic reaction in long-term resuscitation
Phrase: a slow gradual neuronal degeneration induced by chronic hypoxia anisomorphic astrocytosis
Induced genes: gradual
Induced genes: degeneration

---

Effect of chronic hypoxia on K
Phrase: of kca was also significantly inhibited by chronic hypoxia in addition
Repressed genes: kca

---

Chondrocytes in the endochondral growth cartilage are not hypoxic
Phrase: in which hypoxia was artificially induced by death chick chondrocytes were
Inducers of gene: chick
Inducers of gene: chondrocytes

---

Regression of chronic hypoxia-induced pulmonary hypertension, right ventricular hypertrophy, and fibrosis: effect of enalapril
Phrase: prague czech republic chronic hypoxia induces pulmonary hypertension and right ventricular
Induced genes: hypertension
Induced genes: right

---

Effect of exposure to hypoxia from birth on aldosterone in rabbits: role of unesterified fatty acids
Phrase: in inspired o2 hypoxic hypoxia inhibits aldosterone synthesis in the adult
Repressed genes: aldosterone

---

Effects of high-altitude chronic hypoxia on platelet alpha 2-receptors in man
Phrase: that prolonged exposure to hypoxia induces a down-regulation of alpha 2-receptors
Induced genes: 2-receptors

---

Regulation of the resting potential of rabbit pulmonary artery myocytes by a low threshold, O2-sensing potassium current
Phrase: ikn may mediate the depolarization induced by hypoxia
Induced genes: ikn
Induced genes: depolarization

---

Role of Na
Phrase: na+ overload and hepatocyte death induced by hypoxia or cell treatment
Induced genes: na+
Induced genes: overload
Induced genes: hepatocyte

---

Neuronal gagging activity patterns may be generated by neurons in the reticular area dorsomedial to the retrofacial nucleus in dogs
Phrase: kurashiki okayama japan expulsion is induced when hypercapnea and hypoxia develop
Inducers of gene: kurashiki
Inducers of gene: expulsion

---

Mechanisms of hypoxia-induced cerebrovascular dilation in the newborn pig
Phrase: cerebral vasodilation to hypoxia was inhibited by 581114-eicosatetraynoic acid but was
Repressors of gene: 581114-eicosatetraynoic

---

Hypoxia regulates the expression of vascular permeability factor
Phrase: contrast the kdr receptor was downregulated by hypoxia these results suggest
Repressed genes: kdr

---

Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
Phrase: these data demonstrate that hypoxia induces ho-1 expression in animal tissues
Induced genes: ho-1

---

Hypoxia, but not reoxygenation, induces interleukin 6 gene expression through NF-kappa B activation
Phrase: hypoxia but not reoxygenation induces interleukin 6 gene expression through
Phrase: that hypoxia but not reoxygenation induces the activation of nf-kappa b
Phrase: alpha-tocopherol inhibited nf-kappa b activation induced by hypoxia thus we discuss
Induced genes: b
Induced genes: alpha-tocopherol
Induced genes: b

---

Identification of brainstem neurons responding to hypoxia in fetal and newborn sheep
Phrase: carotid chemoreceptors by hypoxia normally inhibits activation of these subcoeruleus neurons
Repressed genes: subcoeruleus

---

Effects of nefiracetam on amnesia animal models with neuronal dysfunctions
Phrase: modifies impairment of memory processes induced by drugs and hypoxia
Induced genes: memory

---

Delayed elevation of plasma endothelin-1 during unilateral alveolar hypoxia without systemic hypoxemia in humans
Phrase: by which acute alveolar hypoxia induces pulmonary vasoconstriction remain unclear we
Induced genes: vasoconstriction

---

Acute and chronic effects of hypoxia on the developing hippocampus
Phrase: hippocampal pathologies associated with experimentally induced hypoxia in immature rats pups
Inducers of gene: pathologies

---

Structural and functional analysis of hypoxia-inducible factor 1
Phrase: beta arnt protein levels were induced by hypoxia in all primary
Phrase: and mrna expression was modestly induced in rodents subjected to hypoxia
Induced genes: arnt

---

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors
Phrase: hep3b cells epo production is induced not only by hypoxia but
Phrase: 50 bp 3' enhancer hypoxia induces hif-1 binding hnf-4 an orphan
Induced genes: hif-1
Induced genes: hnf-4

---

Regulation of tyrosine hydroxylase gene expression during hypoxia: role of Ca2
Phrase: during hypoxia can also be induced by elevations in cytosolic ca2+
Phrase: hypoxia was also only partially inhibited by addition of nifedipine importantly
Repressors of gene: nifedipine

---

Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells
Phrase: glutathion peroxidase that is also induced under hypoxia desferrioxamine however leads
Inducers of gene: glutathion

---

Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase
Phrase: hypoxia 01% oxygen or catalyst induced anoxia but not 1% oxygen
Induced genes: anoxia
Induced genes: 1%

---

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells
Phrase: 3;2721:601-8 hypoxia induces cyclooxygenase-2 via the nf-kappab p65
Induced genes: cyclooxygenase-2
Induced genes: p65

---

Free sterols of the cerebral white matter in experimental severe hypoxia
Phrase: the process of cholesterol biosynthesis induced by the experimental hypoxia the
Induced genes: cholesterol

---

Role of adenosine in the hypoxic induction of vascular endothelial growth factor in porcine brain derived microvascular endothelial cells
Phrase: research bad nauheim germany hypoxia induced the mrna expression of vascular
Phrase: formed during hypoxia and thereby inhibits activation of pkc-independent oxygen sensing
Repressed genes: pkc-independent

---

Different release of cytokines into the cerebrospinal fluid following surgery for intra- and extra-axial brain tumours
Phrase: predominately produced by non-immune cells stimulated through hypoxia or mechanical irritation
Inducers of gene: non-immune

---

Effects of the neuropeptide thyrotropin-releasing hormone on GABAergic synaptic transmission of CA1 neurons of the rat hippocampal slice during hypoxia
Phrase: mechanisms underlying this phenomenon hypoxia induced by superfusion with a medium
Inducers of gene: superfusion

---

Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia
Phrase: these results indicate that hypoxia induces a presynaptic inhibition of excitatory
Induced genes: presynaptic
Induced genes: excitatory

---

Depressant effects of hypoxia and hypoglycaemia on neuro-effector transmission of guinea-pig intestine studied in vitro with a pharmacological model
Phrase: depression of cholinergic neuro-effector transmission induced by hypoxia or nacn effective
Induced genes: depression
Induced genes: cholinergic
Induced genes: neuro-effector
Induced genes: transmission

---

Hypoxic contractile response in isolated rat thoracic aorta: role of endothelium, extracellular calcium and endothelin
Phrase: in this response hypoxia was induced by bubbling krebs solution with
Inducers of gene: bubbling
Inducers of gene: krebs
Inducers of gene: solution

---

Susceptibility of isolated rat facial nerve to anaerobic stress
Phrase: a 40-min period of hypoxia induced by bubbling the solutions with
Inducers of gene: bubbling
Inducers of gene: solutions

---

Activation of the fetal hypothalamic-pituitary-adrenal axis with prolonged and graded hypoxemia
Phrase: the maternal inspired oxygen concentration induced hypoxia n = 12 or
Inducers of gene: inspired

---

Susceptibility of human proximal tubular cells to hypoxia: effect of hypoxic preconditioning and comparison to glomerular cells
Phrase: the cellular level hypoxia was induced by incubating cells in an
Inducers of gene: incubating

---

Hypoxia stimulates atrial natriuretic peptide gene expression in cultured atrial cardiocytes
Phrase: 1:75-82 hypoxia stimulates atrial natriuretic peptide gene expression
Phrase: tested the hypothesis that hypoxia stimulates atrial natriuretic peptide anp gene
Induced genes: atrial
Induced genes: natriuretic
Induced genes: atrial
Induced genes: natriuretic
Induced genes: anp

---

Hypoxia alters the subcellular distribution of protein kinase C isoforms in neonatal rat ventricular myocytes
Phrase: neonatal rat ventricular myocytes hypoxia induces the redistribution of pkc alpha
Induced genes: redistribution

---

The comparative role of haemoglobinaemia and hypoxia in the development of canine babesial nephropathy
Phrase: canine haemoglobin anaemic hypoxia was induced in the 2nd group and
Induced genes: 2nd

---

Role of nitric oxide in the pancreatic vascular and metabolic responses associated with activation of capsaicin-sensitive neurons
Phrase: synthase by n omega-nitro-l-arginine l-nna induced pancreatic ischemia and hypoxia after
Inducers of gene: n
Inducers of gene: omega-nitro-l-arginine
Inducers of gene: l-nna

---

Frequency and amplitude of sympathetic discharges by baroreflexes during hypoxia in conscious rabbits
Phrase: mg/ml total arterial pressure range induced was 80 mmhg hypoxia with
Inducers of gene: mg/ml

---

Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus
Phrase: hypoxia while no seizures are induced at earlier p5 or older
Phrase: slices in mg2+-free media hypoxia induced ictal discharges within 60 s
Induced genes: p5
Induced genes: ictal
Induced genes: discharges
Induced genes: s

---

Sulphonylureas reverse hypoxia induced K
Phrase: sulphonylureas reverse hypoxia induced k+-conductance increase in substantia nigra
Phrase: the whole-cell patch-clamp technique hypoxia induced a consistent decrease in input
Induced genes: k+-conductance
Induced genes: substantia
Induced genes: nigra

---

Hypoxic inhibition of K
Phrase: hypoxia po2 17-23 mmhg reversibly inhibited k+ currents this degree of
Repressed genes: k+
Repressed genes: currents

---

Erythropoietin
Phrase: hypoxia for four weeks hypoxia induced the rise of hematocrit htc
Induced genes: hematocrit
Induced genes: htc
Induced genes: hematocrit
Induced genes: htc

---

Phospholipase A2: a potentially important determinant of adenosine triphosphate levels during hypoxic-reoxygenation tubular injury
Phrase: or pla2 addition respectively hypoxia induced the expected deterioration in adenylate
Induced genes: deterioration
Induced genes: adenylate

---

Hypoxia induces PECAM-1 phosphorylation and transendothelial migration of monocytes
Phrase: 2:h2025-34 hypoxia induces pecam-1 phosphorylation and transendothelial migration
Induced genes: pecam-1
Induced genes: transendothelial
Induced genes: migration

---

Chronic hypoxia induces modification of the N-methyl-D-aspartate receptor in rat brain
Phrase: chronic hypoxia induces modification of the n-methyl-d-aspartate receptor
Induced genes: n-methyl-d-aspartate

---

Hypoxia
Phrase: tension was assessed hypoxia was induced by bubbling the vessels with
Inducers of gene: bubbling
Inducers of gene: vessels

---

Effect of episodic eucapnic and hypocapnic hypoxia on systemic blood pressure in hypertension-prone rats
Phrase: bp changes from hypoxia are induced bp and heart rate were
Induced genes: bp

---

Effect of nitric oxide synthase inhibition on cardiorespiratory responses in the conscious rat
Phrase: responses in control conditions hypoxia induced early ve increases with further
Phrase: response to 10% o2 but induced late ve reductions in hypoxia
Phrase: responses in control animals hypoxia induced a significant heart rate increase
Inducers of gene: 10%
Inducers of gene: o2

---

Acute mountain sickness: increased severity during simulated altitude compared with normobaric hypoxia
Phrase: normoxic hypobaria although normobaric hypoxia induced some ams publication types:
Induced genes: ams

---

A piglet survival model of posthypoxic encephalopathy
Phrase: piglets were halothane-anesthetized hypoxia was induced in 19 piglets by reducing
Induced genes: piglets

---

Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat
Phrase: hypoxic pulmonary hypertension hypoxia also induced brain nos in bronchial epithelium
Phrase: correlated with the vascular remodeling induced by hypoxia suggesting a role
Induced genes: nos

---

Modification of the N-methyl-D-aspartate
Phrase: piglets subjected to ischemic hypoxia induced by hyperventilation paco2 9-11 mmhg
Inducers of gene: hyperventilation
Inducers of gene: paco2
Inducers of gene: 9-11
Inducers of gene: mmhg

---

150-kD oxygen-regulated protein is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxia and modified low density lipoprotein
Phrase: hypoxia po2 approximately 12-14 torr induces orp150 transcripts and production of
Induced genes: orp150

---

Direct preconditioning of cultured chick ventricular myocytes
Phrase: hypoxia protected myocytes against injury induced by the prolonged hypoxia activation
Inducers of gene: hypoxia

---

Systemic hypoxia facilitates somato-cardiac sympathetic A- and C-reflexes in anesthetized rats
Phrase: cardiac sympathetic nerve hypoxia was induced by switching room air to
Inducers of gene: switching
Inducers of gene: room
Inducers of gene: air

---

Effect of buflomedil on the neutrophil-endothelial cell interaction under inflammatory and hypoxia conditions
Phrase: flow and stable systems hypoxia induced neutrophil adhesion 4 hours was
Phrase: results in hypoxia and theophylline inhibited them such results support an
Induced genes: neutrophil

---

Influence of hypoxia and hypoxia-reoxygenation on endothelial P-selectin expression
Phrase: our data indicate that hypoxia induces an increase in p-selectin expression
Induced genes: p-selectin

---

Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention
Phrase: 1996 oct;7510:1753-60 induced hypoxia in rat pulp and
Phrase: maintained at ambient pressure we induced hypoxia by maintaining animals in
Inducers of gene: oct;7510:1753-60
Inducers of gene: ambient

---

[Cardiac surgery using cardiopulmonary bypass in a patient with sickle-cell trait]
Phrase: a the sickle-cell crisis is induced by hypoxia hypercarbia acidosis low
Induced genes: sickle-cell
Induced genes: crisis

---

Effect of inhibition of nitric oxide synthesis on the diaphragmatic microvascular response to hypoxia
Phrase: flow during moderate hypoxia and inhibited arteriolar dilation by an amount
Repressed genes: dilation

---

Alpha 1-adrenergic stimulation induces cardiac tolerance to hypoxia via induction and activation of Mn-SOD
Phrase: alpha 1-adrenergic stimulation induces cardiac tolerance to hypoxia via
Inducers of gene: 1-adrenergic

---

Modulation of hypoxia-induced calpain activity in rat renal proximal tubules
Phrase: tubules pt was determined pd150606 inhibited both hypoxia and ionomycin-induced calpain
Repressors of gene: tubules
Repressors of gene: pd150606

---

Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia
Phrase: these data indicate that hypoxia stimulates vegf-dependent signaling not only by
Induced genes: vegf-dependent

---

Atrial natriuretic factor
Phrase: in the respiratory system: effects induced by hypoxia and hemodynamic overload
Induced genes: system:

---

Vascular cell adhesion molecule-1 is involved in mediating hypoxia-induced sickle red blood cell adherence to endothelium: potential role in sickle cell disease
Phrase: the vitronectin receptor vnr hypoxia upregulated the expression of both vcam-1
Phrase: the bovine aortic ecs hypoxia stimulated the adherence of sickle rbcs
Induced genes: vcam-1
Induced genes: adherence
Induced genes: sickle
Induced genes: rbcs

---

Response of tracheal smooth muscle tone to lower brain stem hypoxia in dogs
Phrase: ventilated dogs central hypoxia was induced by injection of n2-saturated saline
Inducers of gene: n2-saturated
Inducers of gene: saline

---

Alteration in central and peripheral substance P- and neuropeptide Y-like immunoreactivity after chronic hypoxia in the rat
Phrase: in the rat long-term hypoxia induces changes in npy-li or sp-li
Induced genes: npy-li
Induced genes: sp-li

---

Epithelial exposure to hypoxia modulates neutrophil transepithelial migration
Phrase: decreased compared to control hypoxia induced epithelial production and basolateral release
Induced genes: basolateral

---

Renal kallikrein in chronic hypoxic rats
Phrase: sea level sl hypoxia was induced by placing female wistar rats
Inducers of gene: placing

---

Effect of nifedipine on the elimination of theophylline in the rabbit subjected to hypoxia or to an inflammatory reaction
Phrase: decrease in hepatic cytochrome p450 induced by acute moderate hypoxia or
Induced genes: p450

---

Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs
Phrase: verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury
Induced genes: verapamil
Induced genes: coronary
Induced genes: vasospasm

---

Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia
Phrase: in femoral vascular conductance fvc induced by hypoxia by approximately 50%
Phrase: reduced the increase in fvc induced by hypoxia by approximately 50%
Phrase: evidence that the muscle vasodilatation induced by adenosine during systemic hypoxia
Phrase: results also indicate that hypoxia induces muscle vasodilatation that is adenosine
Induced genes: femoral
Induced genes: conductance
Induced genes: fvc
Induced genes: fvc
Induced genes: vasodilatation
Induced genes: vasodilatation
Induced genes: adenosine

---

Endothelium-derived nitric oxide mediates hypoxic vasodilation of resistance vessels in humans
Phrase: venous occlusion plethysmography hypoxia was induced by delivering a mixture of
Inducers of gene: delivering

---

Effects of dexmedetomidine on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices
Phrase: synaptic and extrasynaptic glutamate release stimulated by potassium chloride or hypoxia
Induced genes: synaptic
Induced genes: extrasynaptic
Induced genes: glutamate

---

Specificity and uniqueness of endothelial cell stress responses
Phrase: unique set of stress proteins upregulated by exposure to environmental hypoxia
Phrase: proteins the hap are specifically upregulated only with hypoxia and offer
Inducers of gene: hap

---

Apoptosis, energy metabolism, and fraction of radiobiologically hypoxic cells: a study of human melanoma multicellular spheroids
Phrase: of cell energy metabolism hypoxia- induced apoptosis and radiobiological hypoxia are
Phrase: hypoxic conditions and 3 hypoxia induced apoptosis in wix-c but not
Induced genes: wix-c
Inducers of gene: energy
Inducers of gene: hypoxia-

---

Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans
Phrase: in six subjects hypoxia was induced in eight subjects who inspired
Induced genes: inspired

---

Induction of phosphoglycerate kinase 1 gene expression by hypoxia
Phrase: mouse and human hif1alpha hypoxia induces a 10-fold accumulation of phosphoglycerate
Induced genes: phosphoglycerate

---

Brain cell membrane Na
Phrase: 3 were studied hypoxia was induced by lowering the fio2 to
Inducers of gene: lowering
Inducers of gene: fio2

---

Effect of cerebral hypoxia on NMDA receptor binding characteristics after treatment with 3-
Phrase: prior to hypoxia which was induced by lowering the fio2 to
Inducers of gene: lowering
Inducers of gene: fio2

---

[The inhibitory effects of Radix Astragali on hypoxic pulmonary hypertension of rats]
Phrase: and dilate the constricted ipia induced by hypoxia ra could also
Induced genes: dilate
Induced genes: constricted
Induced genes: ipia

---

Hypoxia in vivo inhibits aldosterone synthesis and aldosterone synthase mRNA in rats
Phrase: hypoxia in vivo inhibits aldosterone synthesis and aldosterone synthase
Repressed genes: aldosterone
Repressed genes: aldosterone

---

Comparison of neurons in rat medulla oblongata with fos immunoreactivity evoked by seizures, chemoreceptor, or baroreceptor stimulation
Phrase: phenylephrine-induced hypertension seizures and hypoxia induced fos immunoreactivity in neurons with
Induced genes: fos

---

Cell signalling in pulmonary vascular cells: do not shoot the messenger
Phrase: changes in vascular tone whether stimulated by hypoxia or other factors
Induced genes: tone

---

Calcium dependence of integrity of the actin cytoskeleton of proximal tubule cell microvilli
Phrase: that occurs during atp depletion induced by antimycin alone or hypoxia
Induced genes: depletion

---

Alkali therapy extends the period of survival during hypoxia: studies in rats
Phrase: in this setting hypoxia was induced in anesthetized paralyzed artificially ventilated
Induced genes: anesthetized
Induced genes: paralyzed
Induced genes: artificially
Induced genes: ventilated

---

Relationship between vasopressin and opioids in hypoxia induced pial artery vasodilation
Phrase: vasopressin and opioids in hypoxia induced pial artery vasodilation
Induced genes: pial
Induced genes: vasodilation

---

Membrane depolarization in PC-12 cells during hypoxia is regulated by an O2-sensitive K
Phrase: at 0 mmhg moreover hypoxia induced a 19-mv membrane depolarization and
Induced genes: 19-mv
Induced genes: depolarization

---

The non-neurogenic catecholamine response of the fetal adrenal to hypoxia is dependent on activation of voltage sensitive Ca2
Phrase: renal vein adrenal hypoxia was induced by perfusion with hypoxic krebs
Phrase: and kcl 10 mm hypoxia stimulated an increase p < 0001
Induced genes: p
Induced genes: <
Inducers of gene: hypoxic
Inducers of gene: krebs

---

[The relationship between peripheral edema and right heart function in COPD induced cor pulmonale]
Phrase: mechanism including hypoxia and hypercapnia induced natrium and water retention right
Induced genes: natrium
Induced genes: right

---

ACTH and growth hormone in myocardial LDH adaptation to hypoxia in rats
Phrase: adaptative changes in ldh isoenzymes induced by hypoxia could be abolished
Induced genes: adaptative
Induced genes: ldh
Induced genes: isoenzymes

---

Hypoxia-induced tetraploidisation of a diploid human melanoma cell line in vitro
Phrase: for the two lines; hypoxia induced increased expression of p53 and
Induced genes: p53

---

Hypoxia does not directly stimulate ischemically sensitive abdominal visceral afferents during ischemia
Phrase: if the regional tissue hypoxia induced by abdominal ischemia directly or
Phrase: data suggest that tissue hypoxia induced by abdominal ischemia is not
Inducers of gene: abdominal
Inducers of gene: abdominal

---

Hypoxia impairs nitrovasodilator-induced pulmonary vasodilation: role of Na-K-ATPase activity
Phrase: in vitro exposure to hypoxia inhibited the relaxant responses of kcl-contracted
Phrase: uptake and this effect was inhibited by hypoxia these results suggest
Repressed genes: relaxant
Repressed genes: kcl-contracted
Repressed genes: uptake

---

Effects of cytochrome P-450 inhibitors on ionic currents in isolated rat type I carotid body cells
Phrase: currents hypoxia 16-23 mmhg reversibly inhibited k+ currents and prevented the
Repressed genes: k+
Repressed genes: currents

---

Regulation of endothelial nitric-oxide synthase during hypoxia
Phrase: baec in this system hypoxia induces a linear increase over time
Phrase: it is concluded that hypoxia induces an increase in transcription of
Induced genes: linear

---

Increase of hypoxic tolerance in rat hippocampal slices following 3-nitropropionic acid is not mediated by endogenous nerve growth factor
Phrase: that early-onset tolerance to hypoxia induced by 3-np treatment is not
Inducers of gene: 3-np

---

Effects of transition metals on the expression of the erythropoietin gene: further evidence that the oxygen sensor is a heme protein
Phrase: of the erythropoietin gene is induced by hypoxia as well as
Induced genes: erythropoietin

---

Is activation of metabotropic glutamate receptors responsible for acute hyposic changes in hippocampal neurons
Phrase: in input resistance or conductance induced by 2 min of hypoxia
Induced genes: conductance

---

Effects of inhaled nitric oxide on hypoxic pulmonary vasoconstriction in dogs and a case report of venae cavae syndrome
Phrase: mean pulmonary arterial pressure mpap induced by hypoxia was lessened significantly
Induced genes: mpap

---

Mild hypoxia induces hypertrophy of cultured neonatal rat cardiomyocytes: a possible endogenous endothelin-1-mediated mechanism
Phrase: mild hypoxia induces hypertrophy of cultured neonatal rat
Phrase: study we examined whether hypoxia induces hypertrophy of cardiomyocytes in vitro
Phrase: to mild hypoxia bq123 partially inhibited either hypoxia-induced [3h]leucine incorporation or
Phrase: data suggest that mild hypoxia induces hypertrophy of cardiomyocytes and that
Induced genes: cardiomyocytes
Induced genes: cardiomyocytes
Repressed genes: hypoxia-induced
Repressed genes: [3h]leucine

---

Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco-2BBe monolayers
Phrase: hyperpermeability and atp depletion induced by chronic hypoxia or glycolytic
Induced genes: hyperpermeability
Induced genes: depletion

---

Hypoxia regulates vascular endothelial growth factor receptor KDR
Phrase: these data suggest that hypoxia induces an initial decline in kdr
Induced genes: kdr

---

Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions
Phrase: or antimycin a chemical hypoxia induces necrotic cell death characterized by
Induced genes: necrotic

---

Effects of acute and chronic hypoxia on rat lung cyclooxygenase
Phrase: in the lung cox-2 expression induced by acute hypoxia was enhanced
Phrase: we conclude that acute hypoxia induces cox-2 gene expression in rat
Phrase: during hypoxia or shear stress induces lung cox-2 expression via a
Induced genes: cox-2
Induced genes: cox-2
Induced genes: cox-2

---

Intracellular pH and intrinsic H
Phrase: to recover from intracellular acidosis induced by hypoxia methods: in nominally
Induced genes: recover
Induced genes: acidosis

---

Sustained systemic arterial hypertension induced by extended hypobaric hypoxia
Phrase: sustained systemic arterial hypertension induced by extended hypobaric hypoxia
Induced genes: hypertension

---

A model for detecting early metabolic changes in neonatal asphyxia by 1H-MRS
Phrase: artery ligation and hypoxia was induced by 10% oxygen inspiration for
Inducers of gene: 10%
Inducers of gene: inspiration

---

Acute hypoxia increases intracellular L-arginine content in cultured porcine pulmonary artery endothelial cells
Phrase: in hypoxic cells hypoxia also inhibited the synthesis of l-arginine-containing proteins
Repressed genes: l-arginine-containing

---

Renal neural response to ischemic renal failure in chronic hypoxic rats
Phrase: chronic hypoxic rats hypoxia was induced by placing the female wistar
Inducers of gene: placing

---

The involvement of cytochrome P4502E1 in 2-bromoethanol-induced hepatocyte cytotoxicity
Phrase: chelators or hypoxia prevented 2-bromoethanol induced lipid peroxidation and cell lysis
Induced genes: lysis

---

Characteristics of the protective action of alpha-Tocopherol in vascular hypoxia
Phrase: conditions the effect of hypoxia induced by bubbling the physiological bathing
Inducers of gene: bubbling
Inducers of gene: bathing

---

Hypoxic pretreatment protects against neuronal damage of the rat hippocampus induced by severe hypoxia
Phrase: damage of the rat hippocampus induced by severe hypoxia
Phrase: protects hippocampal neurones against damage induced by severe 3% o2 hypoxia
Phrase: in unpretreated rats severe hypoxia induced ultrastructural changes consistent with the
Phrase: preconditioning protects against hippocampal damage induced by severe hypoxia the eventual
Induced genes: neurones
Induced genes: ultrastructural
Induced genes: preconditioning

---

Altered oxygen tension modulates cytokine-induced signal transduction in polymorphonuclear leukocytes: regulation of the G PLC pathway
Phrase: early dag formation hypoxia significantly downregulated late dag formation induced by
Repressed genes: dag

---

NGF, BDNF and NT-5, but not NT-3 protect against MPP
Phrase: bfgf can attenuate neuronal damage induced by chemical hypoxia in vivo
Induced genes: bfgf

---

Effect of hypoxia and reoxygenation on regional activity of nitric oxide synthase in brain of newborn piglets
Phrase: only in thalamus since hypoxia induced the greatest decrease in nos
Induced genes: greatest
Induced genes: nos

---

Cytosolic and membrane-bound cerebral nitric oxide synthase activity during hypoxia in cortical tissue of newborn piglets
Phrase: days of age hypoxia was induced by decreasing the fio2 to
Inducers of gene: fio2

---

Predominant role of peripheral chemoreceptors in the termination of apnea in maturing newborn lambs
Phrase: function and hypoxia apneas were induced by passive hyperventilation at varying
Phrase: lambs with central tissue hypoxia induced by co inhalation and 3
Phrase: carotid body removal finally hypoxia induced by either a low inspired
Inducers of gene: passive
Inducers of gene: hyperventilation
Inducers of gene: co
Inducers of gene: inspired

---

Erythropoietin does not demonstrate circadian rhythm in healthy men
Phrase: kidneys in response to hypoxia stimulates the production of red blood
Induced genes: red

---

Comparison of the responses to hypoxia, ischaemia and ischaemic preconditioning in wild marmot and laboratory rabbit hearts
Phrase: better from a bout of induced hypoxia or ischaemia than would
Inducers of gene: bout

---

The role of the renin-angiotensin system in the renal response to moderate hypoxia in the rat
Phrase: mediating the antidiuresis and antinatriuresis induced by moderate systemic hypoxia 2
Phrase: flow and unav however hypoxia induced qualitatively similar changes to those
Phrase: flow and unav whilst hypoxia induced falls in urine flow and
Induced genes: antidiuresis
Induced genes: antinatriuresis
Induced genes: qualitatively
Induced genes: falls

---

Oxygen-elicited responses in calf coronary arteries: role of H2O2 production via NADH-derived superoxide
Phrase: not to hypoxia was significantly inhibited by a scavenger of o2-
Repressors of gene: scavenger
Repressors of gene: o2-

---

Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein
Phrase: observed in normoxia but was induced by hypoxia within 24 h
Induced genes: normoxia

---

Hypoxia inhibits gastric emptying and gastric acid secretion in conscious rats
Phrase: mar;1263:673-80 hypoxia inhibits gastric emptying and gastric acid
Phrase: h after pylorus ligation hypoxia inhibited the secretion of gastric acid
Phrase: due to hypoxia was completely inhibited by oral hcl these results
Phrase: these results demonstrate that hypoxia inhibits gastric emptying and gastric acid
Phrase: hypoxia on gastric acid secretion stimulates gastrin release through positive feedback
Induced genes: gastrin
Repressed genes: emptying
Repressed genes: emptying
Repressors of gene: hcl

---

Aerobic capacity and skeletal muscle properties of normoxic and hypoxic rats in response to training
Phrase: to the reduced body weight induced by hypoxia these data suggest
Phrase: and tolerance for prolonged exercise induced by chronic exposure to hypoxia
Phrase: increase in oxygen carrying capacity induced by hypoxia acclimatization may play
Induced genes: exercise

---

Systemic hypoxia dehydrates the space surrounding photoreceptors in the cat retina
Phrase: intravitreal injection systemic hypoxia was induced by adding nitrogen to the
Phrase: breathing mixture and hyperoxia was induced by adding oxygen results: hypoxia
Inducers of gene: adding
Inducers of gene: nitrogen

---

Altered oxygen tension modulates cytokine-induced signal transduction in polymorphonuclear leukocytes: regulation of the GPLD pathway
Phrase: the hypoxia to hypoxia/reoxygenation transition induced by tnf-alpha-fn and il-1 beta
Inducers of gene: tnf-alpha-fn
Inducers of gene: il-1

---

Effects of Carbicarb and sodium bicarbonate on hypoxic lactic acidosis in newborn pigs
Phrase: lactic acidosis methods: hypoxia was induced by ventilation with 8% o2
Inducers of gene: ventilation
Inducers of gene: 8%
Inducers of gene: o2

---

Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat
Phrase: hypoxia alone in contrast glibenclamide inhibited the relaxant effects of the
Phrase: during hypoxia + hypercapnia charybdotoxin inhibited the relaxant effect of pinacidil
Repressed genes: relaxant
Repressed genes: relaxant
Repressed genes: pinacidil

---

Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages
Phrase: in additional studies adding pge2 inhibited tnf release from the hypoxia
Repressors of gene: adding
Repressors of gene: pge2

---

Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin
Phrase: using rnase protection assays hypoxia induced the expression of glucose transporters
Phrase: manner; glut-1 and glut-3 were induced by hypoxia whereas expression of
Induced genes: manner;
Induced genes: glut-1
Induced genes: glut-3

---

Radioresistance in murine solid tumors induced by interleukin-1
Phrase: is due to hypoxia radioresistance induced by il-1 alpha was transient
Inducers of gene: il-1

---

Influence of hypoxia on hepatic and renal endothelin gene expression
Phrase: tissue hypoxia in rats was induced by five different manoeuvres namely
Inducers of gene: manoeuvres

---

Locally produced tumor necrosis factor-alpha mediates interleukin-2-induced lung injury
Phrase: in bronchoalveolar lavage fluid and induced tissue hypoxia also il-2 enhanced
Inducers of gene: bronchoalveolar
Inducers of gene: lavage
Inducers of gene: fluid

---

Heterogeneity in cytosolic calcium responses to hypoxia in carotid body cells
Phrase: mmhg; 5 min whereas hypoxia induced decreases in [ca2+]i were not
Induced genes: [ca2+]i

---

Factors accounting for different responses of pulmonary and cerebral vessels to hypoxia
Phrase: blockade of atp sensitive pc induced by hypoxia mediated hpv but
Induced genes: blockade

---

Effects of hypoxia on the intercellular channel activity of cultured glomus cells
Phrase: experiments have shown that hypoxia induced by na-dithionite or n2 reduced
Inducers of gene: na-dithionite
Inducers of gene: n2

---

Feeding and breathing in lampreys
Phrase: in lampreys and ammocoetes is stimulated by hypoxia and modulated by
Induced genes: lampreys
Induced genes: ammocoetes

---

Effects of Ginkgo biloba extract
Phrase: cbf and enhanced cbf increases induced by hypoxia these findings indicate
Induced genes: cbf
Induced genes: cbf

---

Effects of hypoxia on carotid body dopamine content and release in developing rabbits
Phrase: de nancy vandoeuvre-les-nancy france hypoxia induces dopamine da release from the
Induced genes: dopamine

---

The vein utilizes different sources of energy than the artery during pulmonary hypoxic vasoconstriction
Phrase: 1 contraction to hypoxia was inhibited and phase 2 contraction was
Repressed genes: contraction

---

Significance of endothelium-derived relaxing factor
Phrase: factor edrf on pulmonary vasoconstriction induced by hypoxia and hypercapnia
Induced genes: edrf
Induced genes: vasoconstriction

---

Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung
Phrase: chronic hypoxia upregulates endothelial and inducible no synthase
Phrase: novel 40-kb species was also induced by hypoxia we conclude that
Induced genes: 40-kb

---

Cellular energy utilization and supply during hypoxia in embryonic cardiac myocytes
Phrase: of cytochrome-c oxidase was partially inhibited during hypoxia in summary these
Repressors of gene: cytochrome-c

---

Acute hypoxia modulates arachidonic acid metabolism in cat carotid bodies
Phrase: these results suggest that hypoxia induces inhibition of aa incorporation on
Induced genes: aa

---

Effects of glucose and oxygen deprivation on phosphoinositide hydrolysis in cerebral cortex slices from neonatal rats
Phrase: 8-day-old rats only glucose-free hypoxia induced a significant increase of inositol
Induced genes: inositol

---

Modulation of erythropoietin production by selective adenosine agonists and antagonists in normal and anemic rats
Phrase: iv-stimulated epo production anemic hypoxia induced by 2% v/w body weight
Inducers of gene: 2%
Inducers of gene: v/w

---

[Effects of subacute hypoxia on alveolar epithelial ion transport in rats]
Phrase: ouabain an inhibitor of na+-k+-atpase inhibited fluid clearance in the hypoxia
Repressors of gene: ouabain
Repressors of gene: na+-k+-atpase

---

Cerebral tissue oxygenation during hypoxia and hyperoxia using artificial placentation in lamb
Phrase: after a lag-time occurred during induced hypoxia an immediate fall of
Phrase: recorded in all cases of induced hypoxia in conclusion the results
Inducers of gene: lag-time

---

[Mechanism of the radiation-protective effect of indralin]
Phrase: it was shown that indralin induced acute hypoxia impaired oxygen consumption
Inducers of gene: indralin

---

The role of accumulation of sodium and calcium on contractile failure of the hypoxic
Phrase: 45 min of reoxygenation hypoxia induced a cessation of cardiac contractile
Phrase: end of hypoxia and also induced a marked increase in myocardial
Induced genes: cardiac
Induced genes: contractile
Induced genes: myocardial

---

Isolation and characterization of the Adh2 5
Phrase: adh genes and other genes induced by hypoxia
Induced genes: adh

---

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences
Phrase: the glucose transporter glut-1 is induced by both hypoxia and mitochondrial
Induced genes: transporter
Induced genes: glut-1

---

Changes in end-expiratory lung volume and diaphragmatic activity during hypoxia and hypercapnia in cats
Phrase: the increase in diaphragmatic activity induced by hypocapnic hypoxia during expiration
Induced genes: diaphragmatic

---

[Hypoxia induced increase of MDA and echinocytes from erythrocytes in rabbit
Phrase: echinocytes from erythrocytes were both inhibited obviously during hypoxia for 24
Repressors of gene: echinocytes
Repressors of gene: erythrocytes

---

Simultaneous measurement of pH and membrane potential in rat dorsal vagal motoneurons during normoxia and hypoxia: a comparison in bicarbonate and HEPES buffers
Phrase: mm hepes acsf hypoxia always induced a depolarization; there was no
Induced genes: depolarization;

---

Hypoxia induces PMN adherence to umbilical vein endothelium
Phrase: dec;306:1009-16 hypoxia induces pmn adherence to umbilical vein
Phrase: ex vivo situations results: hypoxia induced an increase in the adherence
Phrase: in a complete vein hypoxia induced an increased adhesiveness of endothelial
Induced genes: pmn
Induced genes: adherence
Induced genes: umbilical
Induced genes: vein
Induced genes: adherence
Induced genes: adhesiveness

---

Role of ventrolateral medulla catecholamine cells in hypothalamic neuroendocrine cell responses to systemic hypoxia
Phrase: of queensland australia systemic hypoxia stimulates the release of vasopressin vp
Induced genes: vasopressin

---

Hypoxia induces changes in phospholipase A2 in rat proximal tubules: evidence for multiple forms
Phrase: 2:f846-53 hypoxia induces changes in phospholipase a2 in
Induced genes: phospholipase
Induced genes: a2

---

The role of adenosine in mediating vasodilatation in mesenteric circulation of the rat in acute and chronic hypoxia
Phrase: venous vessels respectively the changes induced by acute hypoxia were abolished
Induced genes: venous
Induced genes: vessels

---

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia
Phrase: response to hypoxia was specifically inhibited by low doses of diphenylene
Repressors of gene: diphenylene

---

Opposite modulation of 4-aminopyridine and hypoxic hyperexcitability by A1 and A2 adenosine receptor ligands in rat hippocampal slices
Phrase: the control of hippocampal hyperexcitability induced by hypoxia or 4-aminopyridine but
Induced genes: hyperexcitability

---

Modulating hypoxia-induced hepatocyte injury by affecting intracellular redox state
Phrase: prevented toxicity even though hypoxia induced atp depletion was little affected
Phrase: above results suggests that hypoxia induced hepatocyte injury results from sustained
Induced genes: depletion
Induced genes: hepatocyte

---

Role of histamine H3 receptor on hypoxia-reoxygenation-induced cardiac dysfunction in guinea pigs
Phrase: decreased during reoxygenation however hypoxia induced a marked degranulation of mast
Induced genes: degranulation
Induced genes: mast

---

Inhaled cigarette smoke selectively reverses human hypoxic vasoconstriction
Phrase: gas mixture hypoxia fio2 012 induced a sustained stable pulmonary vasoconstriction
Induced genes: vasoconstriction

---

Theophylline increases coronary vascular tone in humans: evidence for a role of endogenous adenosine in flow regulation
Phrase: different levels of adenosine formation stimulated by hypoxia and exercise six
Induced genes: adenosine

---

Effects of exercise-training on hypoxia and angiotensin II-induced pulmonary vasoconstrictions
Phrase: weeks would inhibit pulmonary vasoconstriction induced by hypoxia in isolated blood-perfused
Induced genes: vasoconstriction

---

[Contribution of oxidative stress to pulmonary hypertension induced by chronic hypoxia]
Phrase: in the pulmonary vascular remodeling induced by chronic hypoxia and reactive
Phrase: contribute to the pulmonary hypertension induced by chronic hypoxia and examined
Phrase: these results indicate that hypoxia induces oxidative stress in the lung
Phrase: the development of pulmonary hypertension induced by chronic hypoxia in rats
Induced genes: hypertension
Induced genes: hypertension

---

Adenosine mediates metabolic and cardiovascular responses to hypoxia in fetal sheep
Phrase: returned to normal 2 hypoxia induced a progressive fetal acidosis a
Induced genes: acidosis

---

Adaptive preservation of ATP and tolerance to hypoxia following carotid artery ligation in the immature rat
Phrase: to identical episodes of hypoxia induced either 3 or 24 h
Induced genes: h

---

Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells
Phrase: 1:l581-7 hypoxia inhibits l-arginine synthesis from l-citrulline in
Phrase: to hypoxia for 4-24 h inhibited arginine synthesis from citrulline in
Phrase: by argininosuccinate synthetase as was inhibited by exposure to hypoxia for
Phrase: arginine by argininosuccinate lyase was inhibited by exposure to hypoxia for
Phrase: these results indicate that hypoxia inhibited the l-arginine biosynthetic pathway via
Repressed genes: l-arginine
Repressed genes: l-citrulline
Repressed genes: arginine
Repressed genes: citrulline
Repressed genes: argininosuccinate
Repressed genes: synthetase
Repressed genes: arginine
Repressed genes: argininosuccinate
Repressed genes: lyase
Repressed genes: l-arginine
Repressed genes: biosynthetic

---

Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells
Phrase: 1:l574-80 hypoxia inhibits l-arginine uptake by pulmonary artery
Repressed genes: l-arginine
Repressed genes: uptake

---

Cell selective induction and transcriptional activation of immediate early genes by hypoxia
Phrase: study we examined whether hypoxia induces ierg expression in isolated cells
Phrase: of low po2 exposure hypoxia stimulated transcription from a 356 bp
Induced genes: ierg
Induced genes: bp

---

Hypoxia induces AP-1-regulated genes and AP-1 transcription factor binding in human endothelial and other cell types
Phrase: 17;12641:72-8 hypoxia induces ap-1-regulated genes and ap-1 transcription
Induced genes: ap-1-regulated
Induced genes: ap-1

---

Depolarization and hypoxia-induced cell damage in serum-free cultures of the rat cortex, and related extracellular glutamate changes
Phrase: changes in extracellular glutamate as induced by hypoxia in serum-free cortical
Phrase: 25 mm k+ the cytotoxicity induced by hypoxia was attenuated by
Induced genes: glutamate
Induced genes: k+

---

Effects of adenosine on norepinephrine and acetylcholine release from guinea pig right atrium: role of A1-receptors
Phrase: therefore adenosine liberated during hypoxia inhibits ne release from the cardiac
Repressed genes: cardiac

---

Hypoxia-induced necrotizing enterocolitis in the immature rat: the role of lipid peroxidation and management by vitamin E
Phrase: into three groups hypoxia was induced by placing the pups in
Inducers of gene: placing
Inducers of gene: pups

---

[The role of endothelin the development of hypoxic pulmonary hypertension]
Phrase: +/- 5kg models with hypoxia induced pulmonary hypertension were established swan-ganz
Phrase: in the development of hypoxia induced pulmonary hypertension ca++-channel blocker nitrendipine
Induced genes: hypertension
Induced genes: swan-ganz
Induced genes: hypertension
Induced genes: ca++-channel
Induced genes: blocker
Induced genes: nitrendipine

---

Kainate receptor modification in the fetal guinea pig brain during hypoxia
Phrase: the guinea pig fetus was induced by exposure to maternal hypoxia
Induced genes: guinea
Induced genes: pig
Induced genes: fetus

---

[Hypoxia stimulates the expression of HSP70 in pulmonary artery smooth muscle cells]
Phrase: to the proliferation of pasmc induced by hypoxia and relevant to
Induced genes: pasmc

---

Nicotinamide methylation and hepatic energy reserve: a study by liver perfusion in vitro
Phrase: triphosphate decrease and energy failure induced by hypoxia or metabolic stress
Induced genes: energy

---

Brief exposure to hypoxia induces bFGF mRNA and protein and protects rat cortical neurons from prolonged hypoxic stress
Phrase: brief exposure to hypoxia induces bfgf mrna and protein and
Phrase: vitro brief exposure to hypoxia induced the production of basic fibroblast
Phrase: model suggest that brief hypoxia induces bfgf protein and thus tolerance
Induced genes: bfgf
Induced genes: bfgf

---

Anoxic induction of a sarcoma virus-related VL30 retrotransposon is mediated by a cis-acting element which binds hypoxia-inducible factor 1 and an anoxia-inducible factor
Phrase: those elicited by hypoxia are induced in anoxic fibroblasts; this includes
Induced genes: anoxic
Induced genes: fibroblasts;

---

NBQX blocks acute and late epileptogenic effects of perinatal hypoxia
Phrase: rat model in which hypoxia induces seizures and permanently increases in
Induced genes: seizures
Induced genes: permanently

---

Adhesion of flowing neutrophils to cultured endothelial cells after hypoxia and reoxygenation in vitro
Phrase: severe hypoxia o2 < 25% induced stationary attachment and then migration
Induced genes: stationary
Induced genes: migration

---

Effects of dextran on hippocampal brain slice water, extracellular space, calcium kinetics and histology
Phrase: the presence of dextran hypoxia induces significant slice water gain a
Induced genes: slice

---

Nitric oxide and ventilatory response to hypoxia
Phrase: hypoxia and caused the hypoxia induced roll-off of phrenic nerve activity
Induced genes: roll-off
Induced genes: phrenic
Induced genes: roll-off
Induced genes: phrenic

---

Cerebral hemodynamics on near-infrared spectroscopy in hypoxia and ischemia in young animal studies
Phrase: recorded during prolonged partial hypoxia induced by carbon dioxide co2 and
Phrase: co2 and nitrogen n2 ischemia induced by hyperventilation and hypoxia during
Induced genes: co2
Induced genes: nitrogen
Induced genes: n2
Inducers of gene: dioxide
Inducers of gene: co2

---

Hormonal changes in normal and polycythemic high-altitude natives
Phrase: exposure to high-altitude ha hypoxia inhibits the renin-angiotensin-aldosterone system and may
Repressed genes: renin-angiotensin-aldosterone

---

A study on rats of the effects of chronic hypoxia from birth on respiratory and cardiovascular responses evoked by acute hypoxia
Phrase: but not the muscle vasodilation induced by acute hypoxia
Induced genes: vasodilation

---

Effect of BQ123 on vasoconstriction as a result of either hypoxia or endothelin-1 in perfused rat lungs
Phrase: in ppa and lung weight induced by hypoxia or angiotensin ii
Induced genes: ppa

---

Simultaneous in vivo comparison of two-versus three-wavelength mixed venous
Phrase: following manipulations: 1 eucarbic hypoxia induced by reducing fio2 to 018
Inducers of gene: fio2

---

Prostaglandin-mediated inhibition of nitric oxide production by bovine aortic endothelium during hypoxia
Phrase: protein during hypoxia hypoxia significantly stimulated the production of pgi2 and
Induced genes: pgi2
Induced genes: pgi2

---

Inhibition of ACTH secretion blocks hypoxia-induced increase of adrenal cortical blood flow in fetal sheep
Phrase: or vehicle fetal hypoxia was induced after 5 h of cortisol
Induced genes: h
Induced genes: cortisol

---

Effect of stretch on contraction and the Ca2
Phrase: stretch-dependent increase in contraction is inhibited during hypoxia and modulated by
Repressors of gene: stretch-dependent
Repressors of gene: contraction

---

Chronic hypoxia differentially regulates alpha 1-adrenergic receptor subtype mRNAs and inhibits alpha 1-adrenergic receptor-stimulated cardiac hypertrophy and signaling
Phrase: we observed that chronic hypoxia inhibited ne-stimulated hypertrophy as reflected by
Phrase: found that chronic hypoxia also inhibited alpha 1-ar-transduced phosphatidylinositol hydrolysis as
Phrase: hypoxia for 72 hours coordinately downregulated both the pharmacologically defined alpha
Phrase: changes conclusions: chronic hypoxia 1 inhibits alpha 1-ar-mediated hypertrophy of cardiac
Repressed genes: ne-stimulated
Repressed genes: 1-ar-transduced
Repressed genes: phosphatidylinositol
Repressed genes: hydrolysis
Repressed genes: pharmacologically
Repressed genes: 1-ar-mediated
Repressed genes: cardiac

---

Optical mapping of translucence changes in rat hippocampal slices during hypoxia
Phrase: spreading depression-like depolarization was not induced if hypoxia duration was sufficient
Inducers of gene: depression-like
Inducers of gene: depolarization

---

Ornithine decarboxylase activity in vitro in response to acute hypoxia: a novel use of newborn rat brain slices
Phrase: to induction of hypoxia we induced hypoxia by changing the oxygen
Induced genes: hypoxia

---

Carotid bodies and ventilatory response to hypoxia in aminophylline-treated piglets
Phrase: late hypoxia after cbd hypoxia induced an initial and sustained depression
Induced genes: depression
Induced genes: depression

---

A short period of hypoxia produces a rapid and transient rise in [K
Phrase: by inhalation transient hypoxia was induced by changing the inspired gas
Phrase: the rise of hippocampal [k+]e induced by hypoxia was influenced by
Induced genes: [k+]e
Inducers of gene: inspired
Inducers of gene: gas

---

Cat brain cytochrome-c oxidase redox changes induced by hypoxia after blood-fluorocarbon exchange transfusion
Phrase: brain cytochrome-c oxidase redox changes induced by hypoxia after blood-fluorocarbon exchange
Induced genes: cytochrome-c

---

Peripheral chemoreceptor function in children with myelomeningocele and Arnold-Chiari malformation type 2
Phrase: p < 002 acute hypoxia induced by n2 tidal breathing resulted
Inducers of gene: n2
Inducers of gene: tidal

---

Active expiratory glottic closure during permeability pulmonary edema in nonsedated lambs
Phrase: expiratory glottic closure was not inhibited after correction of the hypoxia
Repressors of gene: expiratory
Repressors of gene: glottic
Repressors of gene: closure

---

Properties of postganglionic sympathetic fibers isolated from the right recurrent laryngeal nerve
Phrase: neurons n = 1227% were inhibited during systemic hypoxia and their
Repressors of gene: n
Repressors of gene: =
Repressors of gene: 1227%

---

[Experimental studies of physiological and pathological effects induced by systemic hypoxia and the hypoxia-reoxygenation model in rats]
Phrase: of physiological and pathological effects induced by systemic hypoxia and the
Phrase: hypoxia followed by 3-hr reoxygenation induced hypoxia-reoxygenation injuries mostly affecting the
Induced genes: hypoxia-reoxygenation
Induced genes: injuries

---

Functional loss of cerebral blood flow autoregulation in patients with fulminant hepatic failure
Phrase: avoid cerebral hypoxia and/or hypertensive induced cerebral oedema
Induced genes: oedema

---

Endothelin infusion reduces hypoxic pulmonary hypertension in pigs in vivo
Phrase: endotracheal tube and hypoxia was induced by decreasing the fraction inhaled
Phrase: in the right ventricle hypoxia induced a reproducible increase in pulmonary
Inducers of gene: inhaled

---

The incidence and spectrum of neurological injury after open fetal surgery
Phrase: fluxes in cerebral blood flow induced by maternal hypoxia 1 or
Induced genes: fluxes

---

Effects of delta-sleep inducing peptide
Phrase: enhanced ability to counteract hypoxia induced changes in mao-a activity and
Induced genes: mao-a

---

Oxygen tension influences DNA fragmentation and cell death in glucocorticoid-treated thymocytes
Phrase: apoptotic cell death hypoxia also inhibited dna fragmentation induced by calcium
Phrase: hypoxia also inhibited dna fragmentation induced by calcium ionophore a23187 but
Inducers of gene: a23187

---

Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia
Phrase: hypoxia and this increase was inhibited by mk-801 4 we provide
Repressors of gene: mk-801

---

[Acid-base equilibrium and nitrogen metabolism in rats in a state of artificial hibernation]
Phrase: hypothermia hypoxia and hypercapnia has induced development of respiratory acidosis and
Induced genes: acidosis

---

Inhibition of ATP-sensitive potassium channels in cardiac myocytes by the novel class III antiarrhythmic agent MS-551
Phrase: prevent the subsequent ventricular fibrillation induced by pinacidil and hypoxia in
Induced genes: fibrillation

---

Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes
Phrase: occluded vessels cause hypoxia which stimulates sight-threatening abnormal angiogenesis in 50%
Induced genes: sight-threatening
Induced genes: 50%

---

Hypoxia induces HSP 70 gene expression in human hepatoma
Phrase: jul;364:907-12 hypoxia induces hsp 70 gene expression in
Induced genes: hsp

---

Hypoxia-inducible gene expression
Phrase: the transcription-regulating proteins that are induced with hypoxia bind to closely
Inducers of gene: transcription-regulating

---

Influence of perfusate glucose concentration on dialysate lactate, pyruvate, aspartate, and glutamate levels under basal and hypoxic conditions: a microdialysis study in rat brain
Phrase: 6% for glucose hypoxia was induced by lowering the inspired oxygen
Inducers of gene: lowering
Inducers of gene: inspired

---

Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats
Phrase: n-methyl-d-aspartate nmda or chemical hypoxia induced by intrastriatal injection of malonate
Inducers of gene: intrastriatal
Inducers of gene: malonate

---

[Ca2
Phrase: patch-clamp experiments revealed that hypoxia induced by the o2 scavenger sodium
Phrase: that the target k+ channel inhibited by hypoxia is a voltage-dependent
Phrase: rectifier k+ channel which is inhibited by [ca2+]i hypoxia failed to
Phrase: near -65 mv and was inhibited by hypoxia
Inducers of gene: o2
Inducers of gene: scavenger
Inducers of gene: sodium
Repressed genes: k+
Repressed genes: channel
Repressed genes: rectifier
Repressed genes: k+
Repressed genes: channel
Repressed genes: -65

---

Effect of hypoxia on angiotensin II content and its receptor in guinea pig aorta
Phrase: its receptor methods: hypoxia was induced in isolated aorta of guinea
Induced genes: aorta
Induced genes: guinea

---

Changes of 5-hydroxytryptamine release by different glucose concentration from hippocampal slices exposed to hypoxia
Phrase: min period of hypoxia was induced by exchanging the media which
Phrase: these results demonstrate that hypoxia inhibits or enhances 5-ht release in
Inducers of gene: exchanging
Repressed genes: 5-ht

---

Hypoxia-induced alterations of neutrophil membrane receptors
Phrase: how leukocyte accumulation may be induced by ischemia effects of hypoxia
Induced genes: leukocyte

---

Elevated glucose levels increase retinal glycolysis and sorbitol pathway metabolism
Phrase: of free nadh-nad+ like that induced by hypoxia an inhibitor of
Induced genes: nadh-nad+

---

Hypoxic changes in rat locus coeruleus neurons in vitro
Phrase: to abolish spontaneous firing hypoxia induced an early depolarization hd followed
Induced genes: depolarization

---

Different modulation of Ca-activated K channels by the intracellular redox potential in pulmonary and ear arterial smooth muscle cells of the rabbit
Phrase: of ca-activated k kca currents induced by hypoxia and reduction or
Induced genes: ca-activated
Induced genes: k
Induced genes: kca
Induced genes: currents

---

Circulatory and metabolic effects of hypoxia in the hyperinsulinemic ovine fetus
Phrase: tested the hypothesis that hypoxia induced via acutely limiting oxygen availability
Phrase: h were exposed to maternally induced hypoxia hypoxic hypoxia was associated
Induced genes: acutely
Inducers of gene: h
Inducers of gene: h
Inducers of gene: maternally
Inducers of gene: maternally

---

Inhaled nitric oxide improves oxygenation in piglets with meconium aspiration
Phrase: and again after hypoxia was induced by reducing fio2 to 013
Inducers of gene: fio2

---

[Changes of collagen distribution in extrapulmonary arteries of hypoxia-induced pulmonary hypertensive rat]
Phrase: collagen distribution in extrapulmonary arteries induced by hypoxia and the effects
Induced genes: extrapulmonary

---

Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle
Phrase: jun;446:695-8 hypoxia stimulates glucose transport in insulin-resistant human
Phrase: p < 005 hypoxia significantly stimulated glucose transport in muscle from
Phrase: groups hypoxia + insulin significantly stimulated glucose transport in lean obese
Phrase: in diabetic human muscle when stimulated by hypoxia
Induced genes: insulin-resistant
Induced genes: lean
Induced genes: obese
Induced genes: diabetic

---

MK-801 protects against carbon monoxide-induced hearing loss
Phrase: experiment suggests that cochlear impairment induced by co hypoxia may result
Induced genes: experiment
Induced genes: cochlear

---

Hypoxia alters iron homeostasis and induces ferritin synthesis in oligodendrocytes
Phrase: hypoxia alters iron homeostasis and induces ferritin synthesis in oligodendrocytes
Phrase: be determined progressive hypoxia dramatically induces the synthesis of ferritin in
Induced genes: ferritin
Induced genes: ferritin

---

An assessment of central-peripheral ventilatory chemoreflex interaction using acid and bicarbonate infusions in humans
Phrase: ventilatory sensitivity to arterial ph induced by hypoxia 50 torr was
Induced genes: ventilatory

---

Influence of O2 deprivation, reduced flow, and temperature on release of ANP from rabbit hearts
Phrase: were kept constant hypoxia was induced for 20 min at room
Phrase: hypoxia at 37 degrees c induced a significant increase in anp
Induced genes: room
Induced genes: anp

---

Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys
Phrase: death was selectively and rapidly induced by hypoxia in the thick
Phrase: preceding overt morphological damage hypoxia induces rapid dna fragmentation along thick
Induced genes: thick

---

Cardio-ventilatory control in rainbow trout: I
Phrase: receptor discharge it only slightly inhibited responses to hypoxia and nacn
Repressors of gene: discharge

---

Circulatory and respiratory effects of an hypoxic stress in the Siberian sturgeon
Phrase: resulting in bradycardia deep hypoxia induced a ventilatory alkalosis combined with
Induced genes: ventilatory
Induced genes: alkalosis

---

Medullary neuronal activities in gasping induced by pharyngeal stimulation and hypoxia
Phrase: medullary neuronal activities in gasping induced by pharyngeal stimulation and hypoxia
Phrase: the epipharyngeal mucosa and gasping induced by severe hypoxia extracellular neuronal
Induced genes: gasping
Induced genes: epipharyngeal
Induced genes: gasping

---

Protein kinase C-dependent stimulation of Na
Phrase: phospholipase a2 activation a pathway stimulated by hypoxia we evaluated the
Induced genes: phospholipase
Induced genes: a2

---

Effect of nitric oxide on in vitro responsiveness of bovine bronchus and pulmonary vessels
Phrase: hypoxia or kcl 120 mm induced contraction segments of bronchus or
Induced genes: contraction
Induced genes: bronchus

---

Myocardial venous O2 saturation becomes more heterogeneous during hypoxic and carbon monoxide hypoxia
Phrase: four hypoxic conditions hypoxic hypoxia induced by ventilation with either an
Phrase: 20 min or co hypoxia induced by ventilation with a 1%
Inducers of gene: ventilation
Inducers of gene: ventilation
Inducers of gene: 1%

---

Expiratory neural activities in gasping induced by pharyngeal stimulation and hypoxia
Phrase: expiratory neural activities in gasping induced by pharyngeal stimulation and hypoxia
Induced genes: expiratory
Induced genes: gasping

---

[The effect of mechanical ventilation, thoracotomy, and one-lung respiration on intrapulmonary perfusion distribution
Phrase: hypoxia of the nondependent lung induced by nitrogen inflation 1lvn or
Inducers of gene: nitrogen
Inducers of gene: inflation
Inducers of gene: 1lvn

---

Nicotine attenuates the ventilatory response to hypoxia in the developing lamb
Phrase: when peripheral chemoreceptor activity was stimulated by hypoxia 01 fio2 or
Phrase: hypoxia 01 fio2 or briefly inhibited by hyperoxia ventilatory measurements were
Induced genes: chemoreceptor
Repressors of gene: ventilatory

---

Inhibition of adenosine deaminase and administration of adenosine increase hypoxia induced ventricular ectopy
Phrase: administration of adenosine increase hypoxia induced ventricular ectopy leone
Induced genes: ectopy

---

Role of renal nerves in volume expansion in chronic hypoxic rats
Phrase: in these experiments hypoxia was induced by placing the rats in
Inducers of gene: placing

---

Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cells
Phrase: 1:l789-800 hypoxia induces capillary network formation in cultured
Induced genes: capillary

---

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL
Phrase: or bcl-xl prevents cell death induced by withdrawal of oxygen hypoxia
Induced genes: bcl-xl

---

Localization of specific erythropoietin binding sites in defined areas of the mouse brain
Phrase: factor erythropoietin epo which is induced in response to hypoxia binding
Inducers of gene: erythropoietin

---

Effects of levcromakalim and glibenclamide on paced guinea-pig atrial strips exposed to hypoxia
Phrase: of levcromakalim when hypoxia was induced in glucose-free krebs solution with
Induced genes: glucose-free
Induced genes: krebs
Induced genes: solution

---

Effects of hypoxia on the intracellular K
Phrase: during hypoxia po2 2-82 torr induced by na-dithionite aik was measured
Inducers of gene: na-dithionite
Inducers of gene: aik

---

Characterization of a maize G-box binding factor that is induced by hypoxia
Phrase: g-box binding factor that is induced by hypoxia de
Induced genes: g-box

---

[Effect of acute hypoxia on blood viscosity, red blood cell deformability and the left ventricular function in rats]
Phrase: viscosity and if acute hypoxia induced hyperviscosity and elevation of if
Phrase: results suggest that acute hypoxia induces hyperviscosity and decreases of red
Induced genes: hyperviscosity
Induced genes: hyperviscosity
Induced genes: red

---

Role of vagal feedback from the lung in hypoxic-induced tachycardia in humans
Phrase: hearts progressive normocapnic hypoxia was induced over 10-15 min and maintained
Induced genes: 10-15

---

Effect of recurrent episodic hypocapnic, eucapnic, and hypercapnic hypoxia on systemic blood pressure
Phrase: pressure elevation may be maximally stimulated by hypoxia or there may
Induced genes: maximally

---

Acidification of rabbit corneal endothelium during contact lens wear in vitro
Phrase: of lens insertion epithelial hypoxia induced by sodium azide and oligomycin
Phrase: = 4 however epithelial hypoxia induced by perfusion with 100% n2
Inducers of gene: sodium
Inducers of gene: azide
Inducers of gene: oligomycin
Inducers of gene: 100%
Inducers of gene: n2

---

Plasticity in cultured carotid body chemoreceptors: environmental modulation of GAP-43 and neurofilament
Phrase: camp or forskolin also markedly stimulated gap-43 expression since hypoxia is
Phrase: hypoxia however camp analogs also stimulated neurofilament nf 68 or nf
Phrase: in vitro however since hypoxia stimulated gap-43 expression without promoting neurite
Induced genes: nf
Induced genes: nf
Induced genes: gap-43
Induced genes: neurite
Inducers of gene: forskolin

---

Laryngeal response to hypoxia in awake lambs during the first postnatal days
Phrase: adduction we found that hypoxia induced a biphasic ventilatory response with
Induced genes: ventilatory

---

Different involvement of nitric oxide in endothelium-dependent relaxation of porcine pulmonary artery and vein: influence of hypoxia
Phrase: and u 46619 respectively hypoxia induced a transient contractile response that
Induced genes: contractile

---

Modulation of the release of adenosine by glucose and chemical hypoxia in cultured renal cells
Phrase: increased adenosine release deoxyglucose that induces chemical hypoxia stimulated the release
Phrase: deoxyglucose that induces chemical hypoxia stimulated the release of adenosine these
Induced genes: adenosine
Inducers of gene: adenosine
Inducers of gene: deoxyglucose

---

Doppler flow velocimetry of the splenic artery in the human fetus: is it a marker of chronic hypoxia
Phrase: that the increased erythropoietin level stimulated by hypoxia results in decreased
Induced genes: erythropoietin

---

Malignant progression of B16 melanoma cells induced in vitro by growth factors produced by highly malignant cells
Phrase: g35* phenotype both conversions were induced by hypoxia followed by confluence
Induced genes: g35*
Induced genes: conversions

---

Selective inhibition of cyclic adenosine monophosphate-mediated pulmonary vasodilation by acute hypoxia
Phrase: on the other hand hypoxia inhibited beta-adrenergic receptor cyclic adenine monophosphate-mediated
Phrase: data suggest that hypoxia selectively inhibits beta-adrenergic cyclic adenine monophosphate-mediated pulmonary
Repressed genes: beta-adrenergic
Repressed genes: monophosphate-mediated
Repressed genes: beta-adrenergic
Repressed genes: monophosphate-mediated

---

Neuroprotective effect of phenytoin against in utero hypoxic brain injury in fetal guinea pigs
Phrase: phenytoin/ml solvent intraperitoneally hypoxia was induced by exposing the guinea pigs
Inducers of gene: exposing
Inducers of gene: guinea
Inducers of gene: pigs

---

Hypoxic contraction of isolated rabbit mesenteric veins
Phrase: 53226 background: acute systemic hypoxia induces mesenteric venoconstriction in intact rabbits
Phrase: 10% volatile anesthetics 10 mac inhibited responses to hypoxia in the
Induced genes: mesenteric
Induced genes: venoconstriction
Induced genes: rabbits
Repressors of gene: 10%
Repressors of gene: volatile
Repressors of gene: anesthetics
Repressors of gene: mac

---

The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels
Phrase: in the pulmonary arteries hypoxia inhibits potassium current and causes vasoconstriction
Repressed genes: potassium
Repressed genes: vasoconstriction

---

Atrial natriuretic peptide in acute hypoxia-exposed healthy subjects and in hypoxaemic patients
Phrase: in summary severe acute hypoxia induced by hypoxic exercise but not
Inducers of gene: hypoxic
Inducers of gene: exercise

---

Long-term effects of prenatal indomethacin administration on the pulmonary circulation in rats
Phrase: effects of perinatal pulmonary hypertension induced by means other than hypoxia
Induced genes: perinatal
Induced genes: hypertension

---

Heterotopic ossification induced by hypoxia in a retrosternal gastric tube following transhiatal oesophagectomy
Phrase: heterotopic ossification induced by hypoxia in a retrosternal
Induced genes: heterotopic
Induced genes: ossification

---

Effects of the in vitro treatment with gangliosides on the release of endogenous amino acids from rat hypoxic atria
Phrase: release of tau and glu induced by the hypoxia reoxygenation 4
Induced genes: tau
Induced genes: glu

---

An animal model of hypoxia-induced perinatal seizures
Phrase: adult global hypoxia 3-4% o2 induced acute seizure activity during a
Induced genes: seizure

---

Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis
Phrase: and the resultant hypoxia often induces a compensatory neovascularization to satisfy
Induced genes: neovascularization
Induced genes: satisfy

---

Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia
Phrase: in human adenocarcinoma ht29 cells induced by exposure to hypoxia
Phrase: of cells to hypoxia rapidly induces the expression of several immediate
Induced genes: ht29

---

Metabolic aspects of cardiac and skeletal muscle tissues in the condition of hypoxia, ischaemia and reperfusion induced by extracorporeal circulation
Phrase: of hypoxia ischaemia and reperfusion induced by extracorporeal circulation
Inducers of gene: extracorporeal
Inducers of gene: circulation

---

Acute hypoxic vasoconstriction in isolated rat small and large pulmonary arteries
Phrase: study has confirmed that hypoxia induces a biphasic contractile response in
Induced genes: contractile

---

[Comparative study of adaptive responses of the cardiorespiratory system in inhabitants of different climatic-geographic regions]
Phrase: effects of hypoxia and hypercapnia induced by the rebreathing test and
Inducers of gene: rebreathing

---

Acute hypoxia induces elevation of ornithine decarboxylase activity in neonatal rat brain slices
Phrase: acute hypoxia induces elevation of ornithine decarboxylase activity
Phrase: with acsf alone hypoxia was induced in the slices by replacing
Induced genes: ornithine
Induced genes: decarboxylase
Induced genes: slices

---

Murine splenic proliferative response to human recombinant erythropoietin along hypoxia
Phrase: results support suggestions that hypoxia induces a transiently erythroid splenic proliferative
Induced genes: splenic

---

Effects of aprotinin on renal function in chronic hypoxic rats
Phrase: sea level sl hypoxia was induced by placing female wistar rats
Inducers of gene: placing

---

ATP-sensitive K
Phrase: by which the alpha 2d-ar inhibits and hypoxia activates katp channels
Repressors of gene: 2d-ar

---

Effects of 3,4-dihydroxyacetophenone
Phrase: vascular resistance delta svr % induced by 5 min hypoxia decreased
Induced genes: svr
Induced genes: %

---

Role for ATP-sensitive K
Phrase: the substrate-free hypoxia plus 2-deoxyglucose induced the openings of ikatp in
Induced genes: openings
Induced genes: ikatp

---

70-kDa heat shock protein expression in cultured rat astrocytes after hypoxia: regulatory effect of almitrine
Phrase: the decrease of hsc70 immunoreactivity induced by hypoxia furthermore some ultrastructural
Phrase: of hsc70 on cell damage induced by hypoxia
Induced genes: hsc70
Induced genes: hsc70

---

NMDA receptor-mediated sympathetic chemoreflex excitation of RVL-spinal vasomotor neurones in rats
Phrase: that these neurones are directly stimulated by hypoxia
Induced genes: neurones

---

In vitro effects of GABA and hypoxia on posterior hypothalamic neurons from spontaneously hypertensive and Wistar-Kyoto rats
Phrase: in this hypothalamic region are stimulated by hypoxia in vivo and
Phrase: wky 75% neurons that were stimulated by hypoxia were inhibited by
Phrase: were stimulated by hypoxia were inhibited by exogenously applied gaba these
Induced genes: hypothalamic
Induced genes: wky
Induced genes: 75%
Repressors of gene: gaba

---

Is there central fatigue during simulated air combat maneuvering
Phrase: +/- 172 s hypoxia was induced by the sacm as the
Inducers of gene: sacm

---

[Redox fluorometry study of corneal flavoproteins following hypoxia
Phrase: to evaluate the corneal modifications induced by hypoxia at an infraclinical
Induced genes: corneal

---

Assessment of the fetal PO2 changes by cerebral and umbilical Doppler on lamb fetuses during acute hypoxia
Phrase: ovine model acute hypoxia was induced by reducing umbilical or maternal
Inducers of gene: umbilical

---

Interaction of ethanol and anoxia with muscarinic receptor--stimulated phosphoinositide metabolism during brain development
Phrase: hypoxia resulting from ethanol - induced circulatory changes since both ethanol
Induced genes: circulatory
Induced genes: ethanol

---

Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine
Phrase: tumors in rif-1 tumors noarg induced full radiobiological hypoxia when given
Inducers of gene: rif-1
Inducers of gene: noarg

---

Induction of manganese superoxide dismutase in rat cardiac myocytes increases tolerance to hypoxia 24 hours after preconditioning
Phrase: h decreased creatine kinase release induced by sustained hypoxia 3 h
Phrase: decrease in creatine kinase release induced by sustained hypoxia after 24
Induced genes: h
Induced genes: creatine
Induced genes: creatine

---

Protective effect of atrial natriuretic peptide on electrical-field-stimulated rat ventricular strips during hypoxia
Phrase: hypoxic conditions and that hypoxia induces release of atrial natriuretic peptide
Phrase: the amount of cell damage induced during the period of hypoxia
Induced genes: atrial
Induced genes: natriuretic

---

Hypoxic inhibition of breathing in fetal sheep: relationship to brain adenosine concentrations
Phrase: at levels of hypoxia that inhibited fetal breathing under halothane anesthesia
Repressed genes: halothane
Repressed genes: anesthesia

---

Characterization of induced pulpal hypoxia using 3H-misonidazole
Phrase: characterization of induced pulpal hypoxia using 3h-misonidazole
Phrase: at ambient pressure hypoxia was induced by placing animals in a
Inducers of gene: placing

---

[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]
Phrase: relaxation on chronic intermittent hypoxia induced pulmonary hypertension on the right
Induced genes: hypertension
Induced genes: right

---

Pinacidil-induced relaxation in pulmonary arteries isolated from pulmonary hypertensive and normotensive rats and pre-contracted with different spasmogens
Phrase: from rats with pulmonary hypertension induced by chronic hypoxia or monocrotaline
Induced genes: hypertension

---

Effect of hypoxia on proliferation of microvascular endothelial cells derived from Mongolian gerbil brain
Phrase: proliferation of endothelial cells was inhibited by severe hypoxia but stimulated
Phrase: inhibited by severe hypoxia but stimulated by moderate hypoxia no significant
Inducers of gene: hypoxia

---

Vascular clogging, mononuclear cell margination, and enhanced vascular permeability in the pathogenesis of human cerebral malaria
Phrase: noticed in addition to hypoxia induced by prbc-mediated vascular clogging marginating
Inducers of gene: prbc-mediated
Inducers of gene: clogging
Inducers of gene: marginating

---

Interdependence of respiratory and cardiovascular changes induced by systemic hypoxia in the rat: the roles of adenosine
Phrase: of respiratory and cardiovascular changes induced by systemic hypoxia in the
Phrase: 2 in group i hypoxia induced an initial increase and a
Phrase: 3 in group ii hypoxia induced a similar cardiovascular response to
Phrase: the ventilatory and cardiovascular responses induced by hypoxia in the spontaneously
Phrase: 8-pt on the cardiovascular changes induced by hypoxia during spontaneous ventilation
Induced genes: ventilatory
Induced genes: 8-pt

---

Effects of magnesium sulphate and nitric oxide in pulmonary hypertension induced by hypoxia in newborn piglets
Phrase: nitric oxide in pulmonary hypertension induced by hypoxia in newborn piglets
Phrase: model of neonatal pulmonary hypertension induced by hypoxia methods--the cardiac index
Induced genes: hypertension
Induced genes: hypertension

---

Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
Phrase: table of contents hypoxia inhibits expression of enos via transcriptional
Repressed genes: enos

---

1,3-Dipropyl-8-cyclopentylxanthine attenuates the NMDA response to hypoxia in the rat hippocampus
Phrase: of 15 min of hypoxia induced virtual abolition of the nmda
Phrase: of 3 min of hypoxia induced a 893 +/- 123% maximal
Phrase: both periods of hypoxia thus induced a more pronounced depression of
Phrase: all decrease in the fepsp induced by hypoxia 3 min were
Induced genes: virtual
Induced genes: abolition
Induced genes: nmda
Induced genes: 123%
Induced genes: depression
Induced genes: fepsp

---

The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons
Phrase: bicarbonate concentrations 3 the changes induced by hyperglycaemic hypoxia in low
Induced genes: bicarbonate

---

Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells
Phrase: university branch hospital japan adenosine induced by hypoxia exerts various effects
Phrase: induction in u-937 cells hypoxia induced expression of vegf mrna with
Induced genes: adenosine

---

Hypoxia induces voltage-dependent Ca2
Phrase: 11;9121:10208-11 hypoxia induces voltage-dependent ca2+ entry and quantal
Induced genes: voltage-dependent
Induced genes: quantal

---

Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotoninergic neurons of the rat brainstem
Phrase: the carotid bodies by hypoxia induced fos-like immunoreactivity in catecholaminergic neurons
Induced genes: fos-like
Induced genes: catecholaminergic

---

The myocardial effects of fenoterol, isoprenaline and salbutamol in normoxic and hypoxic sheep
Phrase: the experiment was repeated during induced systemic hypoxia and the animals
Inducers of gene: experiment

---

Effect of methylene blue on the vasodilator action of inhaled nitric oxide in hypoxic sheep
Phrase: nine sheep with pulmonary hypertension induced by hypoxia flo2 = 012
Induced genes: sheep
Induced genes: hypertension

---

Hypoxia specifically and reversibly induces the synthesis of ferritin in oligodendrocytes and human oligodendrogliomas
Phrase: hypoxia specifically and reversibly induces the synthesis of ferritin in
Induced genes: ferritin

---

Chemosensitivity, plasticity, and functional heterogeneity of paraganglionic cells in the rat coeliac-superior mesenteric complex
Phrase: utilization rate the dopaminergic activation induced by hypoxia persisted after sympathectomy
Phrase: of their neuromodulators the alterations induced by hypoxia point out the
Induced genes: dopaminergic
Induced genes: neuromodulators

---

Endothelin-1 and cerebral blood flow: influence of hypoxia, hypercapnia and indomethacin on circulating endothelin levels in healthy volunteers
Phrase: that moderate hypoxia protocol a induced a significant increase in cbf
Induced genes: cbf

---

Influence of oxygen on endothelium-derived relaxing factor
Phrase: of hypoxia on acetylcholine ach stimulated endothelium-derived relaxing factor/nitric oxide edrf/no-dependent
Phrase: +/- 36% o2 levels was inhibited by hypoxia 5% emax -362
Induced genes: endothelium-derived
Induced genes: relaxing
Induced genes: factor/nitric
Induced genes: edrf/no-dependent
Repressed genes: 36%
Repressed genes: o2

---

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
Phrase: hypoxia hif-1 activity is also induced by hypoxia in non-erythropoietin-producing cells
Induced genes: hif-1
Inducers of gene: hypoxia
Inducers of gene: non-erythropoietin-producing

---

Oxygen deprivation activates an ATP-inhibitable K
Phrase: test the hypothesis that hypoxia induces activation of k+ channels via
Induced genes: k+

---

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
Phrase: sep;149:6264-77 hypoxia induces accumulation of p53 protein but
Induced genes: p53

---

Hypoxia induces the synthesis of tropomyosin in cultured porcine pulmonary artery endothelial cells
Phrase: 1:l271-81 hypoxia induces the synthesis of tropomyosin in
Phrase: of exposure to hypoxia the upregulated synthesis of the 35- 365-
Phrase: tropomyosin on immunoblot thus hypoxia induces the synthesis of tropomyosin a
Induced genes: tropomyosin
Induced genes: 35-
Induced genes: 365-
Induced genes: tropomyosin

---

[Compensation and adaptation to hypoxia in clinical hypoxyradiotherapy]
Phrase: mechanism to transient systemic hypoxia induced by breathing hypoxic gas the
Inducers of gene: hypoxic
Inducers of gene: gas

---

Nitric oxide is involved in the mediation of gastric blood flow and tissue oxygenation
Phrase: calculated administration of ng-nitro-l-arginine l-nna induced gastric tissue ischemia and hypoxia
Inducers of gene: ng-nitro-l-arginine
Inducers of gene: l-nna

---

Effect of beraprost sodium on changes in action potentials during hypoxia as compared with propranolol, diltiazem and glibenclamide in guinea-pig ventricular muscle
Phrase: k+ content during hypoxia was inhibited furthermore beraprost prevented the action
Repressed genes: beraprost

---

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes
Phrase: sep;753:426-33 hypoxia induces apoptosis with enhanced expression of
Phrase: hours dna fragmentation of cardiomyocytes induced by hypoxia was also confirmed
Induced genes: cardiomyocytes

---

In vitro hypoxia induces expression of the NR2C subunit of the NMDA receptor in rat cortex and hippocampus
Phrase: in vitro hypoxia induces expression of the nr2c subunit
Induced genes: nr2c

---

Changes in human respiratory sensation induced by acute high altitude hypoxia
Phrase: changes in human respiratory sensation induced by acute high altitude hypoxia
Phrase: hyperventilation and mouth pressure increase induced by hypoxia hypoxia might also
Induced genes: sensation
Induced genes: hyperventilation
Induced genes: hyperventilation
Induced genes: mouth
Induced genes: mouth

---

Protective effect of alpha-tocopherol on brain cell membrane function during cerebral cortical hypoxia in newborn piglets
Phrase: of hypoxia hypoxic hypoxia was induced and cerebral hypoxia was documented
Induced genes: hypoxia
Induced genes: hypoxia
Inducers of gene: hypoxic

---

Mechanisms of hypoxic vasoconstriction in the canine isolated pulmonary artery: role of endothelium and sodium pump
Phrase: concentration] subsequent exposure to hypoxia induced a triphasic response: an initial
Induced genes: triphasic
Induced genes: response:

---

Ultrastructural differences between pulmonary arteriolar muscularization induced by hypoxia and monocrotaline
Phrase: differences between pulmonary arteriolar muscularization induced by hypoxia and monocrotaline
Induced genes: muscularization

---

Hypoxia induces release of atrial natriuretic peptide in rat atrial tissue: a role for this peptide during low oxygen stress
Phrase: aug;3502:189-93 hypoxia induces release of atrial natriuretic peptide
Phrase: the question whether hypoxia alone induces release of atrial natriuretic peptide
Induced genes: atrial
Induced genes: natriuretic
Induced genes: atrial
Induced genes: natriuretic

---

Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis
Phrase: in the myocardium is significantly upregulated by hypoxia in vitro and
Induced genes: myocardium

---

Chronic hypoxia affects peripheral and central vasoactive intestinal peptide-like immunoreactivity in the rat
Phrase: results suggest that long-term hypoxia induces alterations in vip systems implicated
Induced genes: vip

---

Hypoxia-induced resistance to doxorubicin and methotrexate in human melanoma cell lines in vitro
Phrase: to hypoxia hypoxic stress also induced methotrexate resistance in bex-c and
Induced genes: methotrexate
Induced genes: bex-c

---

Opposite effects of cyclohexyladenosine and theophylline on hypoxic damage in cultured neurons
Phrase: whereas theophylline enhanced cell injury induced by 8 h hypoxia cyclohexyladenosine
Induced genes: theophylline

---

Deoxyglucose and reduced glutathione mimic effects of hypoxia on K
Phrase: by voltage-gated ca2+ channels hypoxia inhibits voltage-gated k+ kv channels in
Repressed genes: voltage-gated
Repressed genes: k+

---

Extraretinal neovascularization induced by hypoxic episodes in the neonatal rat
Phrase: test the hypothesis that hypoxia induces retinal neovascularization methods to produce
Induced genes: retinal
Induced genes: neovascularization

---

Hypoxia stimulates human endothelial cells to release smooth muscle cell mitogens: role of prostaglandins and bFGF
Phrase: jul;2131:43-54 hypoxia stimulates human endothelial cells to release
Phrase: of prostaglandins by huvec was inhibited during hypoxia pgd2 and especially
Repressors of gene: prostaglandins
Repressors of gene: huvec

---

Hypoxia stimulates prostacyclin synthesis in newborn pulmonary artery endothelium by increasing cyclooxygenase-1 protein
Phrase: jul;751:33-40 hypoxia stimulates prostacyclin synthesis in newborn pulmonary
Induced genes: prostacyclin
Induced genes: newborn

---

Umbilical venous erythropoietin and umbilical arterial pH in relation to morphologic placental abnormalities
Phrase: conclusions: fetal erythropoietin production is stimulated by hypoxia after a few
Induced genes: erythropoietin

---

Enhancement of chlorambucil cytotoxicity by combination with flavone acetic acid in a murine tumour
Phrase: chl is independent of the induced hypoxia which results from blood
Inducers of gene: chl

---

In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia
Phrase: these results suggest that hypoxia induced the release of glut in
Induced genes: glut

---

Hypoxia activates a potassium current in isolated smooth muscle cells from large pulmonary arteries of the rabbit
Phrase: severe hypoxia < 10 mmhg induced relaxation of precontracted rings obtained
Induced genes: precontracted

---

Systemic and myocardial effects of ATP and adenosine during hypoxic pulmonary hypertension in lambs
Phrase: from surgery pulmonary hypertension was induced by exposure to alveolar hypoxia
Induced genes: hypertension

---

Effects of inhibitor of endothelium-derived relaxing factor on hypoxic contraction of isolated pig coronary artery
Phrase: important mechanism of coronary vasoconstriction induced by hypoxia
Induced genes: coronary
Induced genes: vasoconstriction

---

[Effect of hypoxia on the growth and differentiation of NG108-15 cells]
Phrase: of differentiated ones 2 hypoxia inhibited differentiation either non-differentiated or differentiating
Repressed genes: non-differentiated

---

The sensitivity of coronary vascular tone to glibenclamide: a study on the isolated perfused guinea pig heart
Phrase: decrease of coronary perfusion pressure induced by hypoxia and by various
Induced genes: coronary

---

[Alternations of collagen content and collagen gene expression in rat vascular structural remodeling of pulmonary artery induced by hypoxia]
Phrase: remodeling of extrapulmonary artery epa induced by hypoxia were investigated 72
Phrase: content and remodeling of epa induced by hypoxia
Induced genes: extrapulmonary
Induced genes: epa
Induced genes: epa

---

Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle
Phrase: exercise glucose transport activity maximally stimulated with insulin contractions or hypoxia
Inducers of gene: exercise
Inducers of gene: maximally

---

Effect of hypoxia and reoxygenation on the activity of transglutaminase in brain of newborn piglets
Phrase: 18 min period of hypoxia induced by an fio2 of 9%
Inducers of gene: fio2
Inducers of gene: 9%

---

31P MRS to monitor the induction of tumor hypoxia by the modification of the oxygen affinity of hemoglobin using BW 589C
Phrase: oxfordshire uk purpose: bw 589c induces severe tumor hypoxia by modifying
Inducers of gene: oxfordshire
Inducers of gene: bw
Inducers of gene: 589c

---

Acute ventilatory responses to hypoxia during voluntary and electrically induced leg exercise in man
Phrase: hypoxia during voluntary and electrically induced leg exercise in man
Induced genes: leg
Induced genes: exercise

---

Nitric oxide participates in excitotoxic mechanisms induced by chemical hypoxia
Phrase: oxide participates in excitotoxic mechanisms induced by chemical hypoxia
Induced genes: excitotoxic

---

Evidence for role of cytosolic free calcium in hypoxia-induced proximal tubule injury
Phrase: in rat proximal tubules hypoxia induces an increase of [ca2+]i which
Induced genes: [ca2+]i

---

Hypoxia inhibits myogenic reactivity of renal afferent arterioles by activating ATP-sensitive K
Phrase: may;745:861-9 hypoxia inhibits myogenic reactivity of renal afferent
Repressed genes: afferent

---

Life-spanning behavioural and adrenal dysfunction induced by prenatal hypoxia in the rat is prevented by the calcium antagonist nimodipine
Phrase: life-spanning behavioural and adrenal dysfunction induced by prenatal hypoxia in the
Induced genes: life-spanning
Induced genes: behavioural
Induced genes: adrenal

---

Changes in ventilation and oxygen consumption during acute hypoxia in sedated newborn piglets
Phrase: min of hypoxia which was induced by breathing 10% oxygen although
Inducers of gene: 10%

---

Death of cultured postnatal rat CNS neurons by in vitro hypoxia with special reference to N-methyl-D-aspartate-related toxicity
Phrase: hypoxia model the neuronal death induced by the model was attenuated
Phrase: h and removal before hypoxia induced the resistance to hypoxia-mediated cell
Induced genes: hypoxia-mediated

---

Changes in regional pulmonary blood flow during lobar bronchial occlusion in man
Phrase: conditions 2 lobar hypoxia was induced for 80-300 s by placing
Induced genes: 80-300
Induced genes: s
Induced genes: placing

---

[Cardioprotective effect of levcromakalim in isolated guinea pig heart preparations]
Phrase: glycogen lactate and the hypoxia induced decrease in atp and phosphocreatine
Phrase: phosphocreatine the 10 min hypoxia induced increase in lactate and decrease
Induced genes: phosphocreatine

---

[The molecular-cellular regulation of the mitochondrial respiratory chain]
Phrase: both hypoxia and ethyl alcohol induced severe disturbances of energy metabolism
Induced genes: disturbances
Induced genes: energy

---

Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries
Phrase: of endothelium-intact and -denuded arteries induced by pge1 in hypoxia was
Induced genes: endothelium-intact
Induced genes: -denuded

---

HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs
Phrase: < 005 during pulmonary hypertension induced by alveolar hypoxia ha1004 decreased
Induced genes: <
Induced genes: hypertension

---

Protective effect of MgSO4 infusion on nmda receptor binding characteristics during cerebral cortical hypoxia in the newborn piglet
Phrase: hypoxic piglets cerebral hypoxia was induced by lowering the fio2 to
Inducers of gene: lowering
Inducers of gene: fio2

---

Hypoxia stimulates release of ANP and BNP from perfused rat ventricular myocardium
Phrase: 2:h1572-80 hypoxia stimulates release of anp and bnp
Induced genes: anp
Induced genes: bnp

---

The regulation of GRP78 and messenger RNA levels by hypoxia is modulated by protein kinase C activators and inhibitors
Phrase: in grp78 protein and mrna induced by hypoxia can be abolished
Induced genes: grp78

---

Hemodynamic effects and metabolic fate of inhaled nitric oxide in hypoxic piglets
Phrase: in relieving experimental pulmonary hypertension induced by alveolar hypoxia inhaled no
Induced genes: relieving
Induced genes: hypertension

---

Effect of a subanesthetic minimum alveolar concentration of isoflurane on two tests of the hypoxic ventilatory response
Phrase: testing: when normocapnic hypoxia was induced abruptly and when it was
Phrase: in hyperoxia isocapnic hypoxia was induced either abruptly over 60-80 s
Induced genes: abruptly
Induced genes: abruptly
Induced genes: 60-80
Induced genes: s

---

Influence of hypoxia on ventilatory responses to intralaryngeal CO2 in cats
Phrase: the hyperoxic baseline condition hypoxia stimulated phrenic activity but attenuated the
Induced genes: phrenic

---

Postnatal development of hippocampal and neocortical cholinergic and serotonergic innervation in rat: effects of nitrite-induced prenatal hypoxia and nimodipine treatment
Phrase: after long-term prenatal anemic hypoxia induced by chronic exposure to sodium
Phrase: days 1-3; iii prenatal hypoxia induced a transient delay in the
Inducers of gene: sodium

---

[The effects of halothane on the changes in PaCO2, acid-base equilibrium and ventilation induced by hypoxia in the rat]
Phrase: paco2 acid-base equilibrium and ventilation induced by hypoxia in the rat]
Induced genes: paco2
Induced genes: acid-base
Induced genes: equilibrium
Induced genes: ventilation

---

Acute effects of perinatal hypoxic insult on concentrations of dopamine, serotonin, and metabolites in fetal monkey brain
Phrase: oxide oxygen fetal hypoxia was induced in four monkeys by occlusion
Induced genes: monkeys

---

Delayed expression of c-fos protein in rat hippocampus and cerebral cortex following transient in vivo exposure to hypoxia
Phrase: results clearly indicate that hypoxia induces different patterns of c-fos protein
Phrase: related to delayed neuronal damages induced by hypoxia
Induced genes: c-fos
Induced genes: damages

---

Nuclear translocation of heat shock protein 72 in liver cells of halothane-exposed rats
Phrase: nor phenobarbital plus hypoxia treatment induced hsp72 no alteration in amount
Induced genes: hsp72

---

Mechanism of early anoxia-induced suppression of the GABAA-mediated inhibitory postsynaptic current
Phrase: patch-clamp recording and hypoxia was induced by switching perfusion of the
Inducers of gene: switching

---

Brain natriuretic peptide: possible role in the modulation of hypoxic pulmonary hypertension
Phrase: pulmonary vasodilator effects and are upregulated proportionally during chronic hypoxia these
Inducers of gene: vasodilator

---

Control of erythropoiesis in humans during prolonged exposure to the altitude of 6,542 m
Phrase: medecine bobigny france altitude hypoxia induces an increase in erythropoiesis some
Induced genes: erythropoiesis

---

Inhaled nitric oxide partially reverses hypoxic pulmonary vasoconstriction in the dog
Phrase: measurable effects during hyperoxia hypoxia induced an increase in ppa that
Induced genes: ppa

---

Metabolic responses of the dopaminergic system during hypoxia in newborn brain
Phrase: same whether the hypoxia is induced by reduced fio2 high-flow hypoxia
Inducers of gene: fio2
Inducers of gene: high-flow
Inducers of gene: hypoxia

---

Interaction of heat and hypoxia in modulating transcription of DT diaphorase in human colon adenocarcinoma cells
Phrase: of hypoxia was also not inhibited by heat in any schedule
Repressors of gene: schedule

---

Cluster headache: pulse rate changes evoked by hyperoxia and hypoxia
Phrase: headache changes in pulse rate induced by hyperoxia and hypoxia were
Induced genes: headache

---

Monoamine concentrations in cerebrospinal fluid of fetal and newborn sheep
Phrase: fetal and newborn samples hypoxia induced by giving the ewe 9%
Inducers of gene: ewe
Inducers of gene: 9%

---

Delta-1 opioid agonist acutely increases hypoxic tolerance
Phrase: severe intermittent hypoxia hypoxic conditioning induces an acute adaptation such that
Phrase: receptor mimicked acute hypoxic adaptation induced by intermittent hypoxia
Induced genes: hypoxic

---

[The protective effect of MPEG-SOD on the function of left ventricle during acute hypoxia]
Phrase: the injury of myocardial function induced by acute hypoxia and suggest
Induced genes: myocardial

---

Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma
Phrase: we reported recently that hypoxia stimulates gene expression for tyrosine hydroxylase
Induced genes: hydroxylase

---

RAPID AND SIMULTANEOUS MEASUREMENT OF ANODIC AND CATHODIC HAEMOGLOBINS AND ATP AND GTP CONCENTRATIONS IN MINUTE QUANTITIES OF FISH BLOOD
Phrase: 1975; weber 1990 ambient hypoxia induces decreases in erythrocytic ntp wood
Induced genes: erythrocytic
Induced genes: ntp

---

Delta-1 opioid receptor dependence of acute hypoxic adaptation
Phrase: acute adaptation to hypoxia was induced by intermittent severe hypoxia and
Inducers of gene: intermittent
Inducers of gene: hypoxia

---

The relationship between carbon monoxide breathing, tumour oxygenation and local tumour control in the C3H mammary carcinoma in vivo
Phrase: tumour hypoxia and that the induced hypoxia has a significant impact
Induced genes: hypoxia

---

[Dynamics of membrane potential of limb muscular tissue in acute hypoxia induced by blood loss]
Phrase: muscular tissue in acute hypoxia induced by blood loss] [article in
Inducers of gene: loss]
Inducers of gene: [article

---

Effect of hypoxic and carbon monoxide-induced hypoxia on regional myocardial segment work and O2 consumption
Phrase: four hypoxic conditions hypoxic hypoxia induced with either 8% o2 sao2
Induced genes: 8%
Induced genes: o2
Induced genes: sao2

---

In search of the real respiratory neurons: culture of medullary fetal cells sensitive to CO2 and low pH
Phrase: cells also responded to hypoxia induced by administration of sodium hydrosulfite
Inducers of gene: sodium
Inducers of gene: hydrosulfite

---

Effects of calcium antagonists on hypoxic and NMDA injury in rat hippocampal slices
Phrase: from the ca1 electrical failure induced by both hypoxia or nmda
Induced genes: ca1
Induced genes: electrical

---

c-fos-like immunoreactivity in the cat
Phrase: cord both hypoxia and hypercapnia induced c-fos expression in the parabrachial
Induced genes: c-fos
Induced genes: parabrachial

---

Hypoxia-stimulated glycerol production from the isolated, perfused rat heart is mediated by non-adrenergic mechanisms
Phrase: glycerol release during hypoxia was inhibited by both atenolol and timolol
Phrase: failed to reduce glycerol release induced by either hypoxia or severe
Induced genes: glycerol
Repressors of gene: atenolol
Repressors of gene: timolol

---

Nitric oxide
Phrase: also effective in relieving vasoconstriction induced by hypoxia thromboxane analogues and
Induced genes: relieving
Induced genes: vasoconstriction

---

Effect of low dose sedation with diazepam on ventilatory response at moderate altitude
Phrase: paco2 conclusion: low dose diazepam inhibits ventilatory adaptation to mild hypoxia
Repressors of gene: paco2
Repressors of gene: diazepam

---

Effects of 3,4-dihydroxyacetophenone on hypoxic vasoconstriction in isolated pulmonary and basilar arterial rings
Phrase: the percentage increase in tension induced by hypoxia tih% from the
Induced genes: tension

---

The role of atrial natriuretic peptide and endothelin in hypoxia induced pulmonary hypertension
Phrase: peptide and endothelin in hypoxia induced pulmonary hypertension chen
Induced genes: hypertension

---

[Effect of hypoxia on nitric oxide formation and leukotriene metabolism in the perfused rat liver]
Phrase: nmol/g liver/min no2-+no3- release was stimulated by l-arginine infusion whereas hypoxia
Induced genes: nmol/g
Induced genes: liver/min
Induced genes: no2-+no3-

---

Regional cerebral blood flow response to acute hypoxia changes with postnatal age in the rat
Phrase: lcbf measurement at p10 hypoxia induced a 142-415% increase in lcbf
Induced genes: 142-415%
Induced genes: lcbf

---

Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction
Phrase: activation hif-1 dna-binding activity is induced by hypoxia or cobalt chloride
Induced genes: hif-1

---

In vivo and in vitro responses of neurons in the ventrolateral medulla to hypoxia
Phrase: percent of the neurons were stimulated by both hypoxia and hypercapnia
Phrase: of vlm neurons 35/54 were stimulated by hypoxia in a second
Induced genes: vlm
Induced genes: 35/54

---

Disparate effects of adenosine A1- and A2-receptor agonists on intrarenal blood flow
Phrase: the kidney during tissue hypoxia induces heterogeneous renal hemodynamic responses we
Induced genes: hemodynamic

---

Dilator effect of endothelins in pulmonary circulation: changes associated with chronic hypoxia
Phrase: pulmonary circulation and possible changes induced by chronic hypoxia we examined
Induced genes: circulation

---

Metabolic acidemia with hypoxia attenuates the hemodynamic responses to epinephrine during resuscitation in lambs
Phrase: ph was achieved hypoxia was induced until cardiac output decreased to
Induced genes: cardiac
Induced genes: output

---

[Blood rheology in experimental diabetes mellitus]
Phrase: tissue hypoxia developing in diabetes stimulates plasmatic saturation of basal membrane
Induced genes: plasmatic

---

[Frequency of chromosome aberrations induced by hypoxia in cells of the rat bone marrow differing in resistance to this trait]
Phrase: [frequency of chromosome aberrations induced by hypoxia in cells of
Phrase: the frequency of hypoxia induced chromosome aberrations in bone marrow
Induced genes: [frequency

---

Effects of dopamine on the carotid chemosensory response to hypoxia in newborn kittens
Phrase: the response to hypoxia was inhibited in the third cat dopamine
Repressed genes: dopamine

---

Ornithine decarboxylase activity in fetal and newborn rat brain: responses to hypoxic and carbon monoxide hypoxia
Phrase: examined to what extent hypoxia induces increased odc activity in adult
Induced genes: odc

---

Effects of respiratory afferent stimulation on phrenic neurogram during hypoxic gasping in the cat
Phrase: cats during eupnea or gasping induced by hypoxia during eupnea phrenic
Induced genes: cats
Induced genes: eupnea
Induced genes: gasping

---

Adaptive buffering of breath-by-breath variations of end-tidal CO2 of humans
Phrase: in certain experimental protocols eg induced hypoxia any type of induced
Phrase: induced hypoxia any type of induced variations in the ventilatory pattern
Phrase: variations in fetco2 and variations induced by hypoxia in young awake
Induced genes: ventilatory
Induced genes: fetco2

---

Impaired posthypoxic relaxation in single cardiac myocytes: role of intracellular pH and inorganic phosphate
Phrase: snarf-1 fluorescence measured hypoxia was induced in a special open chamber
Induced genes: chamber

---

Dose-response relationship for inhaled nitric oxide in experimental pulmonary hypertension in sheep
Phrase: six sheep with pulmonary hypertension induced first with hypoxia and then
Phrase: pressure occurred in pulmonary hypertension induced by hypoxia or endotoxin with
Phrase: 39 ppm for pulmonary hypertension induced by hypoxia and 48 ppm
Induced genes: hypertension
Induced genes: ppm
Induced genes: hypertension
Inducers of gene: sheep
Inducers of gene: hypertension

---

Effects of naftidrofuryl on hypoxia-induced activation and mortality of human endothelial cells
Phrase: long-term hypoxia incubation 6 h induced cell mortality and naftidrofuryl strongly
Phrase: cells and the cell mortality induced by hypoxia by maintaining an
Induced genes: naftidrofuryl

---

Interaction of the bioreductive drug SR 4233 and photodynamic therapy using photofrin in a mouse tumor model
Phrase: photodynamic therapy to exploit the induced hypoxia sr 4233 was given
Inducers of gene: photodynamic

---

Reductive activation of mitomycin C by NADH:cytochrome b5 reductase
Phrase: hypoxia dicumarol at 100 microm inhibited the nadh:cytochrome b5 reductase-catalyzed reduction
Repressed genes: nadh:cytochrome
Repressed genes: b5
Repressed genes: reductase-catalyzed

---

The influence of vasopressin on the arterioles and venules of skeletal muscle of the rat during systemic hypoxia
Phrase: iv preferentially attenuated constrictor responses induced by hypoxia in both arterioles
Induced genes: constrictor

---

Cluster headache: the ventilatory response to transient hypoxia with pure nitrogen
Phrase: smoking habits transient hypoxia was induced by inhalation of 1-8 breaths
Inducers of gene: 1-8
Inducers of gene: breaths

---

23Na-NMR detects hypoxic injury in intact kidney: increases in sodium inhibited by DMSO and DMTU
Phrase: and after inducing hypoxia hypoxia induced a prompt exponential increase in
Induced genes: prompt
Induced genes: exponential
Induced genes: prompt
Induced genes: exponential

---

Effect of CO2
Phrase: in ph was minimized co2 inhibited ang ii-stimulated aldosterone release hypoxia
Phrase: ang ii-stimulated aldosterone release hypoxia inhibited aldosterone release; the inhibitory effect
Repressed genes: aldosterone
Repressed genes: release;
Repressors of gene: minimized
Repressors of gene: co2

---

Effect of local change in O2 saturation of hemoglobin on cerebral vasodilation from hypoxia and hypotension
Phrase: of hemoglobin on the dilation induced by arterial hypoxia arterial hypotension
Induced genes: dilation

---

Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb
Phrase: 005 similarly during pulmonary hypertension induced by alveolar hypoxia et-1 50-500
Induced genes: hypertension

---

Visualization of high- and low-affinity beta-adrenergic receptors in rat lung: upregulation by chronic hypoxia
Phrase: hospital cleveland ohio chronic hypoxia induces a hyperadrenergic state which down-regulates
Phrase: majority of the additional beta-ars induced during adaptation to chronic hypoxia
Induced genes: hyperadrenergic
Inducers of gene: beta-ars

---

Hypoxia affects differently the intracellular pH of clustered and isolated glomus cells of the rat carotid body
Phrase: to hypoxia po2 2-30 torr induced by applications of sodium-dithionite na2s2o4
Inducers of gene: applications
Inducers of gene: sodium-dithionite
Inducers of gene: na2s2o4

---

Properties of a lactate-induced relaxation in human placental arteries and veins
Phrase: hypoxia relaxation to nitroglycerin was inhibited only by methylene blue and
Repressed genes: methylene

---

Phosphatidylserine synthesis in rat cerebral cortex: effects of hypoxia, hypocapnia and development
Phrase: younger rats 14-18 days hypoxia induced a lesser increase of phosphatidylserine
Induced genes: phosphatidylserine

---

Adenosine antagonists prevent hypoxia-induced depression of excitatory but not inhibitory synaptic currents
Phrase: medicine washington dc 20007 hypoxia induces depression of excitatory postsynaptic currents
Induced genes: depression
Induced genes: excitatory
Induced genes: postsynaptic
Induced genes: currents

---

Interaction of nitric oxide and cyclic guanosine 3
Phrase: of cgmp by hypoxia was inhibited by l-name 100 microm sodium
Repressors of gene: l-name
Repressors of gene: sodium

---

Effect of hypoxia and hyperoxia on postpneumonectomy compensatory lung growth
Phrase: chronic hypoxia enhances whereas hyperoxia inhibits compensatory lung growth the post-caval
Repressed genes: post-caval

---

Effects of hypoxia on stimulus-release coupling mechanisms in cultured bovine adrenal chromaffin cells
Phrase: o2/100% n2 hypoxia cells were stimulated with either nicotine activating nicotinic
Phrase: of nicotinic ach receptors was inhibited by hypoxia both nicotine- and
Induced genes: nicotine
Induced genes: nicotinic
Repressed genes: nicotinic
Repressed genes: ach

---

Peripheral chemoreceptors respond to hypoxia in pontine-lesioned fetal lambs in utero
Phrase: auckland new zealand acute hypoxia inhibits rather than stimulates fetal breathing
Phrase: acute hypoxia inhibits rather than stimulates fetal breathing movements fbm but
Phrase: fourteen fetuses in which hypoxia stimulated fbm underwent either peripheral chemodenervation
Induced genes: movements
Induced genes: fbm
Induced genes: fbm
Induced genes: chemodenervation

---

Effects of hypoxia on oligodendrocyte signal transduction
Phrase: report that hypoxia also dramatically inhibits the basal protein kinase c-mediated
Phrase: hypoxia for 6 h completely inhibited both muscarinic and alpha 1-adrenergic
Repressed genes: c-mediated
Repressed genes: muscarinic
Repressed genes: 1-adrenergic

---

[Sexual asphyxiophilia]
Phrase: or induction of orgasm by induced hypoxia the author draws attention
Inducers of gene: orgasm

---

Effects of beraprost on the transmembrane potentials of guinea-pig ventricular muscles during normoxia and hypoxia-reoxygenation
Phrase: the decrease in contractile force induced by hypoxia whereas it significantly
Induced genes: contractile
Induced genes: force

---

Alloxan diabetes alters the rabbit transarterial wall oxygen gradient
Phrase: these findings suggest that diabetes induces arterial wall hypoxia independent of
Inducers of gene: diabetes

---

[Individual differences in the reactions to acute stress related to behavioral type
Phrase: resistance to circulatory cerebral hypoxia induced by bilateral common carotid arteries
Inducers of gene: bilateral

---

Effects of hypoxia and atrial natriuretic peptide on aldosterone secretion in healthy subjects
Phrase: secretion in hypoxia is not inhibited by pathophysiological plasma anp levels
Repressors of gene: pathophysiological
Repressors of gene: anp

---

Multiple pyruvate decarboxylase genes in maize are induced by hypoxia
Phrase: decarboxylase genes in maize are induced by hypoxia peschke
Induced genes: decarboxylase
Induced genes: maize

---

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves
Phrase: in the sensitivity to hypoxia induced by high concentrations of d-glucose
Inducers of gene: d-glucose

---

Possible involvement of ATP-sensitive K
Phrase: nerve stimulation tns was significantly inhibited at 5 min of hypoxia
Repressors of gene: tns

---

The role of adenosine in hypoxic pulmonary vasoconstriction in the anaesthetized rat
Phrase: anaesthetized with saffan systemic hypoxia induced a tachycardia followed by a
Induced genes: tachycardia

---

Acute hypoxia increases cytosolic calcium in fetal pulmonary artery smooth muscle cells
Phrase: smc sense hypoxia; 2 hypoxia stimulates transmembrane ca2+ influx causing increased
Induced genes: influx

---

Gene expression in low oxygen tension
Phrase: the erythropoietin gene other proteins induced by hypoxia include cytokines platelet-derived
Induced genes: erythropoietin

---

Effect of hypoxia and reoxygenation on the isolated rabbit heart determined by monoclonal antimyosin antibody uptake
Phrase: quantitate the extent of damage induced by hypoxia with and without
Induced genes: quantitate

---

Studies on the effects of endothelin-1
Phrase: following experimental models: hypobaric hypoxia induced by low atmospheric pressure histotoxic
Phrase: low atmospheric pressure histotoxic hypoxia induced by 125 mg/kg kcn ip
Inducers of gene: atmospheric
Inducers of gene: histotoxic
Inducers of gene: kcn

---

Effects of metabolic inhibition on cytoplasmic calcium and contraction in smooth muscle of rat portal vein
Phrase: solution are rapidly and reversibly inhibited by hypoxia or respiratory blockade
Repressed genes: solution

---

Early anoxia-induced vesicular glutamate release results from mobilization of calcium from intracellular stores
Phrase: patch-clamp recording and hypoxia was induced by switching the perfusion of
Inducers of gene: switching

---

Implications of the coronary vascular endothelium as mediator of the vasodilatory and dromotropic actions of adenosine
Phrase: effects of infused adenosine and inhibits the dromotropic effects of hypoxia
Repressors of gene: infused
Repressors of gene: adenosine

---

Endogenous production of superoxide by rabbit lungs: effects of hypoxia or metabolic inhibitors
Phrase: dependent because severe hypoxia completely inhibits light emission superoxide dismutase reduces
Repressed genes: emission

---

Differential modulation by extracellular ATP of carotid chemosensory responses
Phrase: hypoxia perfusate flow interruption but inhibited the response to nicotine 4-nmol
Repressed genes: nicotine
Repressed genes: 4-nmol

---

Pontile regulation of ventilatory activity in the adult rat
Phrase: recorded during hypoxia which was induced by ventilation with carbon monoxide
Inducers of gene: ventilation
Inducers of gene: monoxide

---

[Computer evaluation of respiratory changes during acute hypoxia in an experimental model]
Phrase: air flow signal during experimentally induced hypoxia in model experiment on
Inducers of gene: air

---

Reoxygenation following hypoxia stimulates lipid peroxidation and phosphatidylinositol breakdown in kidney cortical slices
Phrase: reoxygenation following hypoxia stimulates lipid peroxidation and phosphatidylinositol breakdown
Induced genes: phosphatidylinositol
Induced genes: breakdown

---

Action of carbon dioxide on hypoxic pulmonary vasoconstriction in the rat lung: evidence against specific endothelium-derived relaxing factor-mediated vasodilation
Phrase: < 05 at increased tone induced either by hypoxia or angiotensin-ii
Inducers of gene: <
Inducers of gene: tone

---

HIV-1 suppresses erythropoietin production in vitro
Phrase: to cobalt chloride epo production induced by hypoxia of hiv-1 infected
Induced genes: cobalt

---

Ultrastructural demonstration of mitochondrial calcium overload in myocardial cells from broiler chickens with ascites and induced hypoxia
Phrase: broiler chickens with ascites and induced hypoxia maxwell mh
Phrase: ascites and those with an induced hypoxia were used in an
Inducers of gene: broiler
Inducers of gene: chickens
Inducers of gene: ascites
Inducers of gene: ascites

---

Pulmonary vascular impedance vs
Phrase: domain to subtle hemodynamic changes induced by hypoxia or isoflurane at
Induced genes: hemodynamic

---

Regulation of the erythropoietin gene
Phrase: red blood cell production is induced by hypoxia we have utilized
Induced genes: red

---

Species-dependent effects of increasing hypoxia on functions and energy balance in isolated atria
Phrase: lactic acid 2 increasing hypoxia induced a progressive reduction of contractility
Phrase: and rabbit atria hypoxia also induced a progressive reduction of frequency
Induced genes: contractility

---

Isoform-specific effects of transforming growth factors-beta on degeneration of primary neuronal cultures induced by cytotoxic hypoxia or glutamate
Phrase: degeneration of primary neuronal cultures induced by cytotoxic hypoxia or glutamate
Phrase: l-glutamate a cytotoxic hypoxia was induced in cultured chick embryo telencephalic
Induced genes: degeneration
Induced genes: chick
Induced genes: telencephalic

---

Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents
Phrase: 5 min before hypoxia was induced prevention of spontaneous ventricular fibrillation
Phrase: lidocaine and aprindine prevented vf induced by pinacidil and hypoxia
Induced genes: fibrillation
Induced genes: lidocaine
Induced genes: aprindine
Induced genes: vf

---

Lack of the development of morphine tolerance in experimental amnesia: role of arginine vasopressin
Phrase: significant in hypoxia and ischemic induced amnesic animals then recovered to
Induced genes: amnesic

---

Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo
Phrase: telencephalon and cytotoxic hypoxia was induced by adding 1 mm nacn
Inducers of gene: adding
Inducers of gene: nacn

---

Morphological and biochemical evaluation for rigid gas permeable contact lens extended wear on rabbit corneal epithelium
Phrase: related to the contact lens induced corneal hypoxia based on the
Inducers of gene: lens

---

Pathological changes in organs of rats chronically exposed to hypoxia
Phrase: indicate that severe chronic hypoxia induces a significant pulmonary lipidosis similar
Induced genes: lipidosis

---

Hypoxia induces an opsonic mismatch on the polymorphonuclear leukocyte surface-reversal via Arg-Gly-Asp-Ser-mediated adhesion
Phrase: apr;544:299-304 hypoxia induces an opsonic mismatch on the
Phrase: hypoxia monensin but not cycloheximide inhibited rgds restoration of cd16 and
Phrase: acute hypoxia; and 4 rgds upregulates fcr expression during acute hypoxia
Induced genes: opsonic
Inducers of gene: hypoxia;
Inducers of gene: rgds
Repressed genes: rgds
Repressed genes: cd16

---

Hypoxia induces a human macrophage cell line to release tumor necrosis factor-alpha and its soluble receptors in vitro
Phrase: apr;544:281-5 hypoxia induces a human macrophage cell line
Induced genes: macrophage

---

Anaerobiosis and plant growth hormones induce two genes encoding 1-aminocyclopropane-1-carboxylate synthase in rice
Phrase: southeast asia ethylene production is induced by hypoxia which is caused
Induced genes: southeast
Induced genes: asia
Induced genes: ethylene

---

Structure, expression, chromosomal location and product of the gene encoding Adh2 in Petunia
Phrase: expressed developmentally while both are induced in response to hypoxia despite
Inducers of gene: developmentally

---

Activity of tyrosine hydroxylase in the striatum of newborn piglets in response to hypocapnic hypoxia
Phrase: the effect of graded hypoxia induced by hyperventilation on the activity
Inducers of gene: hyperventilation

---

Erythropoietin 5
Phrase: erythropoietin 5'-flanking sequence-binding protein induced during hypoxia and cobalt exposure
Inducers of gene: erythropoietin
Inducers of gene: 5'-flanking
Inducers of gene: sequence-binding

---

The effect of compression on venous stasis
Phrase: subjects this prevents the hypoxia induced by standing the maximum increase
Inducers of gene: standing

---

Modification of human tumour and normal tissue pH during hyperthermic and normothermic antiblastic regional isolation perfusion for malignant melanoma: a pilot study
Phrase: effects of vascular occlusion artificially induced hypoxia hyperglycaemia haemoglobin level of
Inducers of gene: artificially

---

Synergistic antitumor activity of cisplatin and interleukin 1 in sensitive and resistant solid tumors
Phrase: hypoxia nor in vivo ischemia induced by clamping tumor blood supply
Inducers of gene: clamping
Inducers of gene: supply

---

Role of endothelium in biphasic hypoxic response of the isolated pulmonary artery in the rat
Phrase: in the rat hypoxia was induced by gassing an organ chamber
Inducers of gene: gassing
Inducers of gene: organ
Inducers of gene: chamber

---

Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes
Phrase: hypoxic response was only partially inhibited like hypoxia thapsigargin tg elevated
Repressors of gene: hypoxic

---

Hypoxia and hypoxia
Phrase: over time however prolonged hypoxia induced higher igfbp-2 expression in the
Induced genes: igfbp-2

---

Hypoxia induced disruption of the cardiac endothelial glycocalyx: implications for capillary permeability
Phrase: mar;273:384-9 hypoxia induced disruption of the cardiac endothelial
Induced genes: cardiac

---

Hypoxia induces lymphocyte adhesion to human mesenchymal cells via an LFA-1-dependent mechanism
Phrase: 1:c617-24 hypoxia induces lymphocyte adhesion to human mesenchymal
Phrase: monoclonal antibodies mabs hypoxia also induced a reciprocal decrease in lymphocyte-muscle
Induced genes: lymphocyte-muscle

---

Insulin-like growth factor-I gene expression is increased in the right ventricular hypertrophy induced by chronic hypoxia in the rat
Phrase: in the right ventricular hypertrophy induced by chronic hypoxia in the
Induced genes: right

---

Inositol trisphosphate is involved in norepinephrine- but not in hypoxia-induced pulmonary arterial contraction
Phrase: leading to pulmonary arterial contraction induced by hypoxia
Induced genes: contraction

---

Hypoxia inhibits rhodopsin regeneration in the excised mouse eye
Phrase: feb;342:447-52 hypoxia inhibits rhodopsin regeneration in the excised
Repressed genes: rhodopsin
Repressed genes: regeneration

---

The role of endothelium in hypoxic constriction of human pulmonary artery rings
Phrase: 3 g cm-2 and significantly inhibited the contraction produced by hypoxia
Repressors of gene: g
Repressors of gene: cm-2

---

Site of synaptic depression during hypoxia: a patch-clamp analysis
Phrase: patch-clamp recording and hypoxia was induced by switching perfusion of the
Phrase: synaptic response was almost completely inhibited by hypoxia in addition the
Inducers of gene: switching
Repressed genes: synaptic

---

Selective sensitivity of synaptosomal membrane function to cerebral cortical hypoxia in newborn piglets
Phrase: newborn piglets hypoxic hypoxia was induced and cerebral hypoxia was documented
Induced genes: hypoxia
Inducers of gene: newborn
Inducers of gene: piglets
Inducers of gene: hypoxic

---

Recombinant erythropoietin
Phrase: tissue oxygenation; hypoxia or anemia stimulates erythropoietin production and erythrocytosis suppresses
Induced genes: erythropoietin
Induced genes: erythrocytosis

---

Hypoxia induces different responses of striatal high- and low- affinity dopamine uptake sites
Phrase: jan-feb;181-2:179-87 hypoxia induces different responses of striatal high-
Induced genes: striatal
Induced genes: high-

---

Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo
Phrase: nucleotide binding protein mediate hypoxia induced av nodal conduction block in
Phrase: the mechanism of global hypoxia induced atrioventricular av nodal conduction block
Phrase: min periods of global hypoxia induced by decremental changes in o2
Phrase: reduced the degree of hypoxia induced av nodal conduction block and
Induced genes: av
Induced genes: conduction
Induced genes: atrioventricular
Induced genes: av
Induced genes: conduction
Induced genes: av
Induced genes: conduction
Inducers of gene: decremental
Inducers of gene: o2

---

Protective effects of a prostaglandin oligomer on rats exposed to hypoxia
Phrase: oligomer against hypoxia hypoxia was induced in artificially ventilated rats by
Induced genes: artificially
Induced genes: ventilated
Induced genes: artificially
Induced genes: ventilated

---

Abdominal muscle activation by respiratory stimuli in conscious dogs
Phrase: for a given vt whether induced by hypercapnia or hypoxia but
Induced genes: vt

---

Respiratory responses to progressive ambient hypoxia in the sturgeon, Acipenser baeri
Phrase: gradually increasing ambient hypoxia initially induced a respiratory alkalosis below the
Induced genes: alkalosis

---

Oxygen cost of stress development in hypertrophied and failing hearts from the spontaneously hypertensive rat
Phrase: metabolic responses to graded hypoxia induced by changing the gas mixture
Inducers of gene: gas

---

Sleep and respiration under acute hypobaric hypoxia
Phrase: sleep onset by severe hypoxemia induced by multiplicative effects of hypoxia
Induced genes: sleep
Induced genes: hypoxemia

---

Hypothesis for endometrial carcinoma carcinogenesis
Phrase: of true or relative hypoxia stimulates syncytial hyperplasia as adaptive process
Induced genes: syncytial
Induced genes: hyperplasia

---

Responses of feline caudal hypothalamic cardiorespiratory neurons to hypoxia and hypercapnia
Phrase: caudal hypothalamic neurons that are stimulated by hypercapnia or hypoxia is
Phrase: 13% of the neurons were stimulated by both hypoxia and hypercapnia
Induced genes: caudal
Induced genes: hypothalamic
Induced genes: 13%

---

Effect of hypoxia on release of vasoactive substances from cultured pulmonary arterial and aortic endothelial cells
Phrase: not related to hypoxia hypoxia inhibited the production of pgi2 a
Repressed genes: pgi2
Repressed genes: pgi2

---

Sexual asphyxia: a lesser epidemic
Phrase: of gratification depend on hypoxia induced through either strangulation smothering chest
Induced genes: strangulation
Induced genes: smothering
Induced genes: chest

---

Destabilization of the respiratory control by hypoxic ventilatory depressions: a model analysis
Phrase: school of medicine japan hypoxia induces unstable breathing such as cheyne-stokes
Induced genes: cheyne-stokes

---

Early postnatal hypoxia induces long-term changes in the dopaminergic system in rats
Phrase: early postnatal hypoxia induces long-term changes in the dopaminergic
Induced genes: dopaminergic

---

Influences of the endothelium and hypoxia on neurogenic transmission in the isolated pulmonary artery of the rabbit
Phrase: responses to efs 4 hypoxia inhibited the contractile response to efs
Phrase: 2-adrenoceptors in efs-induced contraction hypoxia inhibited neurogenic responses in rabbit isolated
Repressed genes: contractile
Repressed genes: efs
Repressed genes: neurogenic

---

Influence of hypoxia on excitation and GABAergic inhibition in mature and developing rat neocortex
Phrase: somatosensory cortex in vitro hypoxia induced by transient n2 aeration caused
Inducers of gene: n2
Inducers of gene: aeration

---

[Radioprotective effects of hypoxyradiotherapy on saliva secretion]
Phrase: normal tissues transient systemic hypoxia induced by breathing 105% oxygen gas
Inducers of gene: 105%
Inducers of gene: gas

---

Effects of graded levels of tissue oxygen pressure on dopamine metabolism in the striatum of newborn piglets
Phrase: these data suggest that hypoxia induces long-term alterations in the neurotransmitter
Induced genes: neurotransmitter

---

Effect of hypoxia on the intracellular chloride activity of cultured glomus cells of the rat carotid body
Phrase: hypoxia 54 +/- 08 torr induced by na-dithionite na2s2o4 125 mm
Inducers of gene: na-dithionite
Inducers of gene: na2s2o4

---

Endothelin-1 does not mediate acute hypoxic pulmonary vasoconstriction in the intact newborn lamb
Phrase: by which acute alveolar hypoxia induces pulmonary vasoconstriction remain unclear previous
Phrase: pressure and pulmonary vascular resistance induced by alveolar hypoxia before and
Induced genes: vasoconstriction

---

High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia
Phrase: and organ dysfunction can be induced by hypoxia
Induced genes: organ

---

Serine incorporation into phosphatidylserine in hypoxic rat brain cortex
Phrase: ringer phosphate and hypoxia was induced by bubbling nitrogen in the
Inducers of gene: bubbling
Inducers of gene: nitrogen

---

Effects of hypoxia on the discharge of group III and IV muscle afferents in cats
Phrase: iii and iv afferents hypoxia stimulated 4 of 11 contraction-sensitive group
Phrase: the responses of the afferents stimulated by hypoxia were small in
Induced genes: contraction-sensitive
Induced genes: afferents

---

In search of the central respiratory neurons: II
Phrase: cells also responded to hypoxia induced by administration of sodium hydrosulfite
Inducers of gene: sodium
Inducers of gene: hydrosulfite

---

Does a subanesthetic concentration of isoflurane blunt the ventilatory response to hypoxia
Phrase: normoxia to isocapnic hypoxia was induced using a dynamic end-tidal forcing
Induced genes: dynamic
Induced genes: end-tidal
Induced genes: forcing

---

Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements
Phrase: human erythropoietin epo gene is stimulated by exposure to hypoxia and/or
Induced genes: erythropoietin

---

In vitro responses of caudal hypothalamic neurons to hypoxia and hypercapnia
Phrase: in the caudal hypothalamus are stimulated by hypercapnia and hypoxia in
Phrase: extracellular recordings demonstrated that hypoxia stimulated over 80% of the neurons
Induced genes: caudal
Induced genes: hypothalamus
Induced genes: 80%

---

Changes of fibronectin in the right and left ventricles of rats exposed to chronic normobaric hypoxia
Phrase: which indicates that pulmonary hypertension induced by chronic hypoxia rather than
Phrase: of the hypertrophied right ventricle induced by chronic hypoxia
Induced genes: hypertension
Induced genes: hypertrophied
Induced genes: right

---

Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells
Phrase: under hypoxia in vitro was inhibited by at least 95% in
Repressors of gene: 95%

---

[Hydralazine-induced enhancement of hyperthermia treatment in vivo]
Phrase: low ph and tumor hypoxia induced by arterial embolization may have
Inducers of gene: embolization

---

Dual responses of carotid chemosensory afferents to dopamine in the newborn kitten
Phrase: to hypoxia were studied dopamine inhibited the chemosensory discharge in 25/44
Repressed genes: chemosensory
Repressed genes: discharge
Repressed genes: 25/44

---

Increased normoxic ventilation induced by repetitive hypoxia in conscious dogs
Phrase: increased normoxic ventilation induced by repetitive hypoxia in conscious
Induced genes: normoxic
Induced genes: ventilation

---

Determinants of poststimulus potentiation in humans during NREM sleep
Phrase: during nrem sleep hypoxia was induced for 15 s 30 s
Induced genes: s
Induced genes: s

---

Age-dependent changes in long-term seizure susceptibility and behavior after hypoxia in rats
Phrase: hypoxia at p5 and p60 induced no long-term changes in seizure
Induced genes: seizure

---

Hypoxia-elicited contraction of aorta and coronary artery via removal of endothelium-derived nitric oxide
Phrase: norepinephrine 10-7 m severe hypoxia induced an initial increase in tension
Phrase: +/- 57% relaxation; moderate hypoxia induced only a sustained increase in
Induced genes: tension

---

Limitations of laser-Doppler velocimetry and reflectance spectrophotometry in estimating gastric mucosal blood flow
Phrase: experimental conditions such as pharmacologically induced vasoconstriction hypoxia hyperoxia and acute
Inducers of gene: pharmacologically

---

Implications of a pre-existing tumor hypoxic fraction on photodynamic therapy
Phrase: compared to tumors with an induced hypoxic fraction tumor hypoxia was
Phrase: hypoxic fraction tumor hypoxia was induced by using vasoactive drugs epinephrine
Inducers of gene: vasoactive
Inducers of gene: epinephrine

---

Hypoxia induces synthesis of a novel 22-kDa protein in neonatal rat oligodendrocytes
Phrase: nov;595:1709-16 hypoxia induces synthesis of a novel 22-kda
Induced genes: 22-kda

---

[Lysosomal apparatus of some body tissues in hemorrhage-induced hypoxia]
Phrase: rats with acute circulatory-hemic hypoxia induced by hemorrhage in amount of
Inducers of gene: hemorrhage

---

[Study on prophylactic hypoxyradiotherapy to whole abdomen and pelvis]
Phrase: normal tissues transient systemic hypoxia induced by breathing 105% oxygen gas
Inducers of gene: 105%
Inducers of gene: gas

---

Adenosine
Phrase: in the genesis of bradyarrhythmias induced by acute myocardial hypoxia
Phrase: locality of a-v conduction block induced by both myocardial hypoxia and
Induced genes: bradyarrhythmias
Induced genes: locality
Induced genes: a-v
Induced genes: conduction

---

Class III antiarrhythmic action by potassium channel blockade: dofetilide attenuates hypoxia induced electromechanical changes
Phrase: channel blockade: dofetilide attenuates hypoxia induced electromechanical changes yang
Phrase: during hypoxia methods: hypoxia was induced by superfusing guinea pig right
Phrase: of baseline respectively these hypoxia induced effects were significantly attenuated after
Phrase: effectively attenuates hypoxia and nicorandil induced action potential shortening and the
Induced genes: electromechanical
Inducers of gene: superfusing
Inducers of gene: guinea
Inducers of gene: pig
Inducers of gene: right
Inducers of gene: superfusing
Inducers of gene: guinea
Inducers of gene: pig
Inducers of gene: right

---

Eicosapentaenoic and docosahexaenoic acids in cultured rat ventricular myocytes and hypoxia-induced alterations of phospholipase-A activity
Phrase: higher in dha-rich cardiomyocytes hypoxia induced a significant decrease in pc-pla2
Induced genes: pc-pla2

---

Role of endothelium-derived prostaglandins in hypoxia-elicited arteriolar dilation in rat skeletal muscle
Phrase: removal of the endothelium completely inhibited responses to hypoxia acetylcholine and
Phrase: an intact endothelium indomethacin completely inhibited the responses to hypoxia and
Repressors of gene: indomethacin

---

Exercise induced release of von Willebrand factor: evidence for hypoxic reperfusion microvascular injury in rheumatoid arthritis
Phrase: hypoxia and reperfusion hypoxia reperfusion induced vwf release by human umbilical
Induced genes: vwf
Induced genes: umbilical
Induced genes: vwf
Induced genes: umbilical

---

Effect of age and blood pressure on the heart rate, vasopressin, and renin response to hypoxia in fetal sheep
Phrase: did not attenuate the bradycardia induced by hypoxia plasma renin activity
Induced genes: bradycardia

---

The control of cardiac chronotropic function in hypobaric hypoxia
Phrase: medecine bobigny france altitude hypoxia induces an increase in adrenergic activity
Induced genes: adrenergic

---

Effects of hypoxia on choline exchange among organs
Phrase: to 10-20-min periods of hypoxia induced by lowering the inspired o2
Inducers of gene: lowering
Inducers of gene: inspired
Inducers of gene: o2

---

[Acid-base disturbances in heart failure]
Phrase: hypoxia due to pulmonary edema stimulates ventilation resulting in respiratory alkalosis
Induced genes: ventilation
Induced genes: alkalosis

---

BW12C-induced changes in haemoglobin-oxygen affinity in mice and its influence on the radiation response of a C3H mouse mammary carcinoma
Phrase: these results suggest that bw12c induced changes in tumour hypoxia reported
Inducers of gene: bw12c

---

Chronic respiratory alkalosis induces renal PTH-resistance, hyperphosphatemia and hypocalcemia in humans
Phrase: days of chronic respiratory alkalosis induced by hypobaric hypoxia residence at
Induced genes: alkalosis

---

Ventilatory and metabolic responses to cold and hypoxia in intact and carotid body-denervated rats
Phrase: decrease in ta; 2 hypoxia induced only a transient decrease in
Phrase: nonshivering thermogenesis may be directly inhibited by hypoxia especially during cold
Repressed genes: nonshivering
Repressed genes: thermogenesis

---

PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats
Phrase: antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats
Phrase: development of chronic pulmonary hypertension induced by chronic hypoxia
Induced genes: antagonists
Induced genes: hypertension

---

Effects of high altitude exposure on plasma and urinary digoxin-like immunoreactive substance
Phrase: altered water and electrolyte balance induced by hypoxia we studied dlis
Induced genes: electrolyte

---

The role of calcium activated neutral protease on myocardial cell injury in hypoxia
Phrase: endogenous selective calpain inhibitor markedly inhibited extracellular protease activity during hypoxia
Phrase: activity during hypoxia nco-700 also inhibited intracellular protease activity nco-700 reduced
Repressed genes: nco-700
Repressors of gene: calpain

---

Role of cytochrome P-450 from the human CYP3A gene family in the potentiation of morpholino doxorubicin by human liver microsomes
Phrase: 1989 this metabolic potentiation is inhibited by carbon monoxide or hypoxia
Repressed genes: potentiation

---

Hypoxia induces glucose transporter expression in endothelial cells
Phrase: 1:c326-33 hypoxia induces glucose transporter expression in endothelial
Induced genes: transporter

---

[Effect of potassium channel openers on hypoxic pulmonary vasoconstriction]
Phrase: m or lemakalim 10-5 m inhibited the pressor response to hypoxia
Repressors of gene: m
Repressors of gene: lemakalim
Repressors of gene: 10-5
Repressors of gene: m

---

Expression of muscle capillary alkaline phosphatase is affected by hypoxia
Phrase: oakland university rochester 48309-4401 hypoxia stimulates angiogenesis in some microvascular beds
Induced genes: microvascular
Induced genes: beds

---

Chemoreceptor and baroreceptor responses of A1 area neurons projecting to supraoptic nucleus
Phrase: 40 were excited and 25 inhibited by hypercapnic hypoxia of 23
Phrase: by hypercapnia of 16 neurons inhibited by hypercapnic hypoxia 15 were
Phrase: by hypercapnic hypoxia 15 were inhibited by hypoxia and 1 was
Phrase: by hypoxia and 1 was inhibited by hypercapnia of 14 neurons
Phrase: carotid artery of five neurons inhibited by hypoxia four were inhibited
Phrase: inhibited by hypoxia four were inhibited by sodium cyanide our results
Repressed genes: excited
Repressed genes: hypercapnia
Repressed genes: hypercapnic
Repressors of gene: hypoxia
Repressors of gene: hypercapnia
Repressors of gene: sodium
Repressors of gene: cyanide

---

Identification and characterization of a hypoxically induced maize lactate dehydrogenase gene
Phrase: in cereal root tissue hypoxia induces the enzyme lactate dehydrogenase ldh;
Phrase: indicate that five isozymes are induced under hypoxia these isozymes are
Induced genes: ldh;
Inducers of gene: isozymes

---

[A comparative study of the activity of antihypoxic agents in hemic hypoxia]
Phrase: in acute toxic hemic hypoxia induced by sodium nitrite given to
Inducers of gene: sodium
Inducers of gene: nitrite

---

Short-term interaction of airway and tissue oxygen tensions on ciliary beat frequency in dogs
Phrase: combination with alveolar hypoxia cbft stimulated with 100% oxygen insuffiated to
Induced genes: 100%
Induced genes: insuffiated

---

Increase of plasma neuropeptide Y-like immunoreactivity following chronic hypoxia in the rat
Phrase: data suggest that chronic hypoxia induced an elevation of circulating npy
Induced genes: circulating
Induced genes: npy

---

Role of endogenous opioid peptides in the acute adaptation to hypoxia
Phrase: blocked the adaptation to hypoxia induced by hypoxic conditioning p =
Phrase: the protective adaptation to hypoxia induced by prior exposure to non-lethal
Inducers of gene: hypoxic
Inducers of gene: conditioning
Inducers of gene: p
Inducers of gene: =
Inducers of gene: non-lethal

---

Is the mean power frequency shift of the EMG a selective indicator of fatigue of the fast twitch motor units
Phrase: a relative ischaemia hypoxia was induced 2 a submaximum test performed
Phrase: 50 contractions when hypoxia was induced decreases in mechanical performance and
Induced genes: submaximum
Induced genes: mechanical

---

Vascular changes and their mechanisms in the feline model of retinopathy of prematurity
Phrase: and obliteration during hyperoxia vasoproliferation induced by hypoxia and normalization after
Induced genes: obliteration
Induced genes: vasoproliferation

---

The effect of hypoxia on the epileptiform activities induced by magnesium-free medium in rat brain slices
Phrase: hypoxia on the epileptiform activities induced by magnesium-free medium in rat
Inducers of gene: magnesium-free

---

[Metabolic factors of vasomotor regulation of the inner retina]
Phrase: the mediator of the hypoxia induced vasodilation on retinal arterioles in
Induced genes: vasodilation
Induced genes: retinal
Induced genes: arterioles

---

Acute cyanide poisoning: a case report with toxicokinetic study
Phrase: which itself causes hypoxia nitrite induced methemoglobin can be extremely dangerous
Induced genes: methemoglobin
Induced genes: dangerous

---

Endothelium-dependent and independent cGMP mechanisms appear to mediate O2 responses in calf pulmonary resistance arteries
Phrase: the contraction to hypoxia and inhibited the relaxation to reoxygenation whereas
Repressed genes: reoxygenation

---

Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity
Phrase: and xo activity in ec induced by hypoxia were associated upon
Induced genes: xo

---

Comparison of carbon monoxide and nitrogen induced effects on synaptic transmission in the rat hippocampal slice
Phrase: different during or following hypoxia induced by exposure to co or
Inducers of gene: co

---

[Protective effects of naftidrofuryl oxalate against hypoxia-induced death]
Phrase: bi could improve cerebrovascular disorders induced by hypoxia
Induced genes: bi
Induced genes: improve
Induced genes: cerebrovascular

---

Response of noradrenaline and dopamine to hypoxia and sympathectomy: evidence for an independent dopaminergic reactivity
Phrase: was suppressed by sympathectomy hypoxia induced large increases in dopamine concentration
Induced genes: dopamine

---

[Effect of hypoxia on vasodilation induced by substance P
Phrase: [effect of hypoxia on vasodilation induced by substance p sp and
Phrase: effect of hypoxia on vasodilation induced by substance p sp and
Phrase: on the third hypoxia vasodilation induced by cgrp 28 x 10-9
Inducers of gene: substance
Inducers of gene: p
Inducers of gene: substance
Inducers of gene: p
Inducers of gene: cgrp
Inducers of gene: x
Inducers of gene: 10-9

---

Hypoxia-induced functional alterations in adult rat neocortex
Phrase: of hypoxia 2-7 min were induced in rat neocortical slices maintained
Phrase: 40% of the cells hypoxia induced an early anoxic hyperpolarization with
Induced genes: neocortical
Induced genes: slices
Induced genes: anoxic
Induced genes: hyperpolarization

---

Different effects of hypoxia on the membrane potential and input resistance of isolated and clustered carotid body glomus cells
Phrase: bodies hypoxia po2 1-61 torr induced by na-dithionite na2s2o4 differentially affected
Inducers of gene: na-dithionite
Inducers of gene: na2s2o4

---

Control of metabolic and ventilatory responses to cold in anesthetized cats
Phrase: thermogenesis component may also be inhibited by hypoxia the decrease in
Repressed genes: thermogenesis

---

Modulatory role of EDRF in hypoxic contraction of isolated porcine pulmonary arteries
Phrase: hypoxia significantly reduced endothelium-dependent relaxation induced by acetylcholine and augmented contractile
Inducers of gene: acetylcholine
Inducers of gene: augmented
Inducers of gene: contractile

---

Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries
Phrase: 6-keto-pgf1 alpha and txb2 contractions induced by hypoxia of human coronary
Phrase: hand dog coronary artery contractions induced by hypoxia were attenuated by
Induced genes: 6-keto-pgf1
Induced genes: txb2
Induced genes: contractions
Induced genes: dog
Induced genes: coronary
Induced genes: contractions

---

Evaluation of N-0861,
Phrase: stimulus to his bundle prolongation induced by either hypoxia or reduced
Induced genes: bundle
Induced genes: prolongation

---

Neuroprotective effect of WEB 1881 FU
Phrase: uptake and ca1 field potentials induced by hypoxia and hypoxia/hypoglycemia ischemia
Induced genes: uptake
Induced genes: ca1

---

Mechanisms underlying induced autoresuscitation failure in BALB
Phrase: apnea were investigated failure was induced by repeated exposure to hypoxia
Induced genes: apnea

---

Modulation of autoregulatory escape by capsaicin-sensitive afferent nerves in rat stomach
Phrase: 91343 visceral c fibers are stimulated by ischemia and hypoxia which
Induced genes: visceral
Induced genes: c
Induced genes: fibers

---

[Effects of acute and protracted hypoxia on plasma levels of atrial natriuretic factor]
Phrase: mare pomezia roma acute hypoxia stimulates the release of atrial natriuretic
Induced genes: atrial
Induced genes: natriuretic

---

Effects of calcium antagonists on glycolysis of rat brain synaptosomes
Phrase: to in vitro chemical hypoxia induced by rotenone an inhibitor of
Inducers of gene: rotenone

---

Reoxygenation associated radiosensitization after chronic hypoxia: effect of temperature and oxygen tension
Phrase: during 12 hr of hypoxia inhibited the sensitization seen after reoxygenation
Repressed genes: sensitization
Repressed genes: reoxygenation

---

Hypoxia inhibits calcium influx in rabbit basilar and carotid arteries
Phrase: 2:h106-13 hypoxia inhibits calcium influx in rabbit basilar
Phrase: examined the hypothesis that hypoxia inhibits ca2+ influx in isolated rabbit
Phrase: three artery types and hypoxia inhibited this increase by 74% in
Phrase: carotid above control hypoxia completely inhibited serotonin- and/or utp-induced increases in
Repressed genes: influx
Repressed genes: basilar
Repressed genes: influx
Repressed genes: 74%
Repressed genes: serotonin-
Repressed genes: utp-induced

---

Peroxyl radical-mediated hemolysis: role of lipid, protein and sulfhydryl oxidation
Phrase: at 120 min hemolysis was inhibited by hypoxia and by the
Repressed genes: hemolysis

---

Role of sympathetic nerve and adrenal gland in the potentiation of hypoxic pulmonary vasoconstriction during cigarette smoking
Phrase: of pulmonary vascular resistance pvr induced by alveolar hypoxia was partially
Induced genes: pvr

---

Responses to vasodilator drugs on pulmonary artery preparations from pulmonary hypertensive rats
Phrase: from rats with pulmonary hypertension induced by monocrotaline or chronic hypoxia
Induced genes: hypertension

---

Effects of hypoxia and reoxygenation on steady-state and potentiated contractions in papillary muscle of guinea pigs
Phrase: the first period of hypoxia induced a gradual recovery in steady-state
Induced genes: gradual

---

Ventilatory effects of prolonged systemic
Phrase: which whole body hypoxia is induced cns hypoxia did not result
Phrase: significant role for cns mechanisms induced by hypoxia in ventilatory acclimatization
Induced genes: hypoxia

---

A potassium current activated by lemakalim and metabolic inhibition in rabbit mesenteric artery
Phrase: of physiological phenomena including hypoxia induced vasodilation however electrophysiological evidence for
Phrase: to the view that hypoxia induced vasodilation arises from the activation
Induced genes: vasodilation
Induced genes: electrophysiological
Induced genes: vasodilation

---

Persistent pulmonary hypertension complicating cystic adenomatoid malformation in neonates
Phrase: combined with hypoxia and hypercarbia stimulates a hyperactive pulmonary vasculature and
Induced genes: vasculature

---

Benefit from long-term O2 therapy in chronic obstructive pulmonary disease patients
Phrase: in the pulmonary vessels possibly induced by chronic alveolar hypoxia and
Induced genes: vessels

---

Fetal breathing, sleep state and cardiovascular adaptations to anaemia in sheep
Phrase: returned to normal isocapnic hypoxia induced less than 1 h later
Induced genes: h

---

Enhancement of hypoxia radioprotection and decrease of hypoxia toxicity caused by adenosine monophosphate
Phrase: and amp join with those induced by hypobaric hypoxia the hypotensive
Induced genes: join

---

Age-related differences in vascular effects of pentoxifylline in isolated perfused ferret lungs
Phrase: of the increase in resistance induced by hypoxia 80% was eliminated
Phrase: lungs 51% elimination of tone induced by hypoxia this difference was
Induced genes: lungs
Induced genes: 51%
Induced genes: tone

---

An experimental model for simultaneous quantitative analysis of pulmonary micro- and macrocirculation during unilateral hypoxia in vivo
Phrase: fluorescence videomicroscopy during unilateral hypoxia induced by one-lung ventilation 1 lv
Inducers of gene: one-lung
Inducers of gene: ventilation
Inducers of gene: lv

---

Hypoxia-induced von Willebrand factor release is blocked by verapamil
Phrase: 1 microgram/ml attenuated the hypoxia induced stimulation 048 +/- 007%; p
Induced genes: 007%;
Induced genes: p

---

Dose-response studies with co-dergocrine mesylate under hypoxia utilizing EEG mapping and psychometry
Phrase: due to hypoxia was experimentally induced by a fixed gas combination
Phrase: the behavioral level moderate hypoxia induced a deterioration of noopsychic performance
Induced genes: deterioration
Induced genes: noopsychic
Inducers of gene: gas

---

Further studies on the hypoxia produced by canatoxin in rats
Phrase: the seeds of canavalia ensiformis induces lipoxygenase-dependent hypoxia in rats which
Inducers of gene: seeds
Inducers of gene: canavalia
Inducers of gene: ensiformis

---

Different mechanisms of hypoxic relaxation in canine coronary arteries and rat abdominal aortas
Phrase: prostaglandin f2 alpha respectively hypoxia induced transient relaxations 20 +/- 2
Induced genes: relaxations

---

Long-term hypoxia induces changes in the substance P immunoreactivity pattern in laryngeal nerve paraganglia
Phrase: long-term hypoxia induces changes in the substance p
Phrase: neuropeptides and catecholamine-synthesizing enzymes hypoxia induced an intense cellular substance p
Phrase: the results show that hypoxia induces changes in the pattern of
Induced genes: substance
Induced genes: p
Induced genes: substance
Induced genes: p

---

Carotid body chemoreception in the absence and presence of CO2-HCO3-
Phrase: 20-25 torr and ischemic hypoxia stimulated the discharge in the absence
Induced genes: discharge

---

[The role of polycythemia in the pathogenesis of hypoxic myocardial hypertrophy]
Phrase: either chronic hypoxia or polycythemia induced by cocl2 injection resulted in
Phrase: chronic hypoxia combined with polycythemia induced by cocl2 injection further augmented
Inducers of gene: cocl2
Inducers of gene: cocl2
Inducers of gene: augmented

---

[Effect of cigarette smoke extract on hypoxic pulmonary vasoconstriction]
Phrase: more remarkable pulmonary vasoconstriction was induced by hypoxia than before cse
Phrase: strengthen pulmonary vasoconstriction and hypertension induced by acute alveolar hypoxia
Induced genes: vasoconstriction
Induced genes: strengthen
Induced genes: vasoconstriction
Induced genes: hypertension

---

Cyclic AMP modulates differentially the release of dopamine induced by hypoxia and other stimuli and increases dopamine synthesis in the rabbit carotid body
Phrase: differentially the release of dopamine induced by hypoxia and other stimuli
Induced genes: dopamine

---

Effect of age and hypoxia on beta-adrenergic receptors in rat heart
Phrase: previous reports suggest that hypoxia downregulates cardiac beta-adrenergic receptors from young
Repressed genes: cardiac
Repressed genes: beta-adrenergic

---

Vinpocetine increases the neuroprotective effect of adenosine in vitro
Phrase: hypoxic damage cytotoxic hypoxia was induced by adding 1 mm sodium
Inducers of gene: adding
Inducers of gene: sodium

---

Hypoxia induces endothelial cell synthesis of membrane-associated proteins
Phrase: 1;8821:9897-901 hypoxia induces endothelial cell synthesis of membrane-associated
Induced genes: membrane-associated

---

[The structural characteristics of the auditory portion of the cerebral cortex in the Baikal seal
Phrase: cortex of pusa sibirica during induced 18-min hypoxia has shown that
Inducers of gene: pusa
Inducers of gene: sibirica

---

The role of adenosine in dilator responses induced in arterioles and venules of rat skeletal muscle by systemic hypoxia
Phrase: hypoxia 2 during systemic hypoxia induced by breathing 6% o2 for
Inducers of gene: 6%
Inducers of gene: o2
Inducers of gene: 6%
Inducers of gene: o2

---

Effects of oxygen tension on endothelium dependent responses in canine coronary microvessels
Phrase: in coronary microvessels hypoxia also induces a prostaglandin mediated dilatation of
Induced genes: prostaglandin
Induced genes: dilatation

---

The mechanism of photosensitization in photodynamic therapy: phosphorescence behavior of porphyrin derivatives in saline solution containing human serum albumin
Phrase: interpreted in terms of hypoxia induced by photosensitization in a local
Inducers of gene: photosensitization

---

Aortic and carotid body chemoreception in prolonged hyperoxia in the cat
Phrase: augmented the aortic chemoreceptors were stimulated by hypoxia hypercapnia cyanide and
Induced genes: augmented
Induced genes: aortic
Induced genes: chemoreceptors

---

Calpain is activated by beta-adrenergic receptor stimulation under hypoxic myocardial cell injury
Phrase: agents and calcium antagonists also inhibited intracellular calcium-influx during hypoxia these
Phrase: elevated intracellular calcium concentration then stimulates calpain activity under hypoxia these
Repressors of gene: antagonists

---

L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs
Phrase: effects however during pulmonary hypertension induced by hypoxia or the infusion
Induced genes: hypertension

---

Suppression of Ca2
Phrase: of chemical hypoxia intracellular acidosis induced by 40 mm na-acetate suppressed
Phrase: plasma membrane; 2 chemical hypoxia inhibits hormone-stimulated ca2+ flux pathways across
Inducers of gene: na-acetate
Repressed genes: hormone-stimulated
Repressed genes: flux

---

Effects of K
Phrase: hypoxia nifedipine but not phentolamine inhibited hypoxic vasoconstriction and prevented the
Repressed genes: hypoxic
Repressed genes: vasoconstriction

---

Specific proteins synthesized in human lymphocytes during hypoxia
Phrase: have previously shown that hypoxia induces the synthesis of unique proteins
Phrase: protein for which synthesis is upregulated by hypoxia its isoelectric point
Phrase: during exposure to hypoxia significantly inhibited hyp synthesis
Repressed genes: hyp

---

BW12C: effects on tumour hypoxia, tumour thermosensitivity and relative tumour and normal tissue perfusion in C3H mice
Phrase: the increase in tumour hypoxia induced by bw12c
Inducers of gene: bw12c

---

Effects of hypoxia and cold acclimation on thermoregulation in the rat
Phrase: nca and ca rats hypoxia induced a transient decrease in shivering
Induced genes: shivering

---

Ventilatory effects and interactions with change in PaO2 in awake goats
Phrase: we conclude that ventilation is stimulated by systemic hypoxia and hyperoxia
Induced genes: ventilation

---

Characterization of endothelium-derived relaxing factor
Phrase: production was investigated hypoxia markedly inhibited edrf/no synthase activity whereas hyperoxia
Phrase: production was measured hypoxia almost inhibited the production of cyclic gmp
Phrase: dismutase we conclude that hypoxia inhibits edrf/no synthase activity primarily through
Repressed genes: edrf/no
Repressed genes: gmp
Repressed genes: edrf/no

---

Vasoconstriction to hypoxia of the human internal mammary artery
Phrase: vessels without endothelium hypoxia only induced relaxation to 10 +/- 2%
Phrase: these experiments indicate that hypoxia induces the release of an endothelium-derived
Induced genes: 2%
Induced genes: endothelium-derived

---

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium
Phrase: sep;883:1054-7 hypoxia induces endothelin gene expression and secretion
Induced genes: endothelin

---

Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig
Phrase: shortening of apd and erp induced by hypoxia in guinea pig
Induced genes: apd
Induced genes: erp

---

Posterior cricoarytenoid activity and glottic size during hyperpnea in humans
Phrase: normal human subjects during hyperpnea induced by hypoxia 7% co2 in
Induced genes: hyperpnea

---

Hypoxia induced hearing loss in animal models of the fetus in-utero
Phrase: sep;551:92-7 hypoxia induced hearing loss in animal models
Phrase: this is due to hypoxia induced depression of the endocochlear potential
Phrase: model hypoxia pao2 20-30 mmhg induced an abr threshold elevation resembling
Induced genes: hearing
Induced genes: depression
Induced genes: endocochlear
Induced genes: abr
Induced genes: resembling

---

Effects of continuous infusion of atrial natriuretic peptide on the pulmonary hypertension induced by chronic hypoxia in rats
Phrase: peptide on the pulmonary hypertension induced by chronic hypoxia in rats
Induced genes: hypertension

---

Enhancer element at the 3
Phrase: erythropoietin gene expression is greatly stimulated under conditions of hypoxia the
Inducers of gene: erythropoietin

---

Hypoxia-induced change in prostanoids production and coronary flow in isolated rat heart
Phrase: the change in coronary flow induced by hypoxia was examined in
Induced genes: coronary

---

Pentoxifylline inhibits interleukin-2-induced leukocyte-endothelial adherence and reduces systemic toxicity
Phrase: 1 x 106 units/kg acutely induced hypotension tachypnea hypoxia increased lung
Inducers of gene: x
Inducers of gene: units/kg
Inducers of gene: acutely

---

Enhancement of post-hypoxic contractile and metabolic recovery of perfused rat hearts by dl-propranolol: possible involvement of non-beta-receptor mediated activity
Phrase: myocardial metabolism were examined hypoxia induced complete cessation of cardiac contractile
Induced genes: cardiac
Induced genes: contractile

---

O2 and rat pulmonary artery tone: effects of endothelium, Ca2
Phrase: pa precontracted with phenylephrine hypoxia induced an initial e-dependent relaxation phase
Phrase: response to hypoxia was not inhibited by cyanide thus hypoxia produces
Induced genes: e-dependent
Repressors of gene: cyanide
Repressors of gene: hypoxia

---

Preserved CO2 response in cerebral and muscular blood vessels during cimetidine treatment
Phrase: during hypoxia acute hypercapnia was induced in 12 conscious dogs in
Induced genes: conscious

---

O2 pressures between 0
Phrase: collected the n2 off-gassed hypoxia induced a significant 94% p less
Induced genes: 94%
Induced genes: p

---

Beneficial effects of yohimbine on posthypoxic recovery of cardiac function and myocardial metabolism in isolated perfused rabbit hearts
Phrase: yohimbine treatment were examined hypoxia induced cessation of cardiac contractile force
Phrase: by subsequent reoxygenation hypoxia also induced release of creatine kinase and
Induced genes: cardiac
Induced genes: contractile
Induced genes: force
Induced genes: creatine

---

Interaction of chemical and mechanical respiratory stimuli in the arousal response to hypoxia in sleeping dogs
Phrase: and isocapnic progressive hypoxia was induced by a rebreathing technique arousal
Inducers of gene: rebreathing
Inducers of gene: arousal

---

Interaction of baroreceptor and chemoreceptor reflex control of sympathetic nerve activity in normal humans
Phrase: chemoreceptors in humans pc were stimulated by hypoxia 10% o2/90% n2
Induced genes: chemoreceptors

---

The cardiopulmonary and metabolic effects of hypoxia during acute adrenocortical suppression by etomidate in the dog
Phrase: of anesthesia isocarbic hypoxia was induced for 20 minutes cardiopulmonary and
Induced genes: cardiopulmonary

---

Almitrine in low dose potentiates vasoconstrictor responses of isolated rat lungs to moderate hypoxia
Phrase: high dose augments pulmonary vasoconstriction induced by mild degrees of hypoxia
Induced genes: vasoconstriction

---

Hypoxia-stimulated reduction of doxyl stearic acids in human red blood cells
Phrase: least 2 h but hypoxia stimulated spin label reduction complete signal
Induced genes: spin
Induced genes: label

---

Oxygen regulated 80 kDa protein and glucose regulated 78kDa protein are identical
Phrase: respectively the commonality of proteins induced by glucose-starvation and hypoxia has
Induced genes: commonality

---

The roles of catecholamines in responses evoked in arterioles and venules of rat skeletal muscle by systemic hypoxia
Phrase: systemic arterial pressure and tachycardia induced by hypoxia 3 all arterioles
Induced genes: tachycardia

---

Inhibition by barium and glibenclamide of the net loss of 86Rb
Phrase: and glibenclamide on the hypoxia induced k+ efflux from rabbit myocardium
Phrase: than 001 conclusions--part of hypoxia induced net k+ loss in this
Induced genes: k+
Induced genes: efflux
Induced genes: myocardium
Induced genes: net
Induced genes: k+

---

Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells
Phrase: hypoxia also increased cytokine production induced by the tumor promoter phorbol
Inducers of gene: phorbol

---

The effect of acute hypoxia on right ventricular function in healthy adults
Phrase: an acute rise in afterload induced by hypoxia
Induced genes: afterload

---

Influence of adenosine and prostacyclin on hypoxia-induced pulmonary hypertension in the anaesthetized pig
Phrase: each experimental sequence hypoxia was induced by reducing fio2 to 012-013
Inducers of gene: fio2
Inducers of gene: 012-013

---

Effect of hypoxia and catecholamine stimulation on cardiac performance in the isolated working hyperthyroid rat heart
Phrase: working hyperthyroid heart hypoxia was induced by substituting 20% of the
Inducers of gene: substituting
Inducers of gene: 20%

---

Effect of alpha adrenergic blockade on brain blood flow and ventilation during hypoxia in newborn piglets
Phrase: after 10 min of hypoxia induced by breathing 10% o2 hypoxia
Phrase: 10% o2 hypoxia was again induced one hour after infusion of
Induced genes: hour
Induced genes: infusion
Inducers of gene: 10%
Inducers of gene: o2
Inducers of gene: hypoxia

---

Effectiveness of glibenclamide on myocardial ischemic ventricular arrhythmias in non-insulin-dependent diabetes mellitus
Phrase: channels in the myocardial cells induced by acute myocardial hypoxia can
Induced genes: myocardial

---

Hypoxia inhibits renal thromboxane and not prostacyclin release
Phrase: apr;334:244-8 hypoxia inhibits renal thromboxane and not prostacyclin
Repressed genes: thromboxane
Repressed genes: prostacyclin

---

Cyanide-induced alteration of the adenylate energy pool in a rat neurosecretory cell line
Phrase: cytoprotective activity against histotoxic hypoxia induced by cyanide since pc12 cells
Inducers of gene: cyanide

---

Effects of hypoxaemia and bradycardia on neonatal cerebral haemodynamics
Phrase: of hypoxia both spontaneous and induced impairment of haemoglobin oxygenation within
Induced genes: haemoglobin
Induced genes: oxygenation

---

Morphometric measurements of chorioallantoic membrane vascularity: effects of hypoxia and hyperoxia
Phrase: day we conclude that hypoxia stimulates angiogenesis in the cam in
Induced genes: cam

---

Endogenous arachidonic acid metabolism by calcium ionophore A23187-stimulated lamb lungs: effect of hypoxia
Phrase: lungs the increased production by stimulated lungs during hypoxia of lte4
Inducers of gene: lungs

---

Hypoxia induced metabolism dysfunction of rat astrocytes in primary cell cultures
Phrase: apr;164:423-8 hypoxia induced metabolism dysfunction of rat astrocytes
Phrase: mainly m subunits is specifically induced by hypoxia our results suggest
Induced genes: m

---

Effects of H2-receptor blockers on response of cerebral blood flow to normocapnic hypoxia
Phrase: abolished the increase of cbf induced by hypoxia in conclusion h2-receptor
Induced genes: cbf

---

[The dynamics of the chromatin transcription activity in cerebellar Purkinje cells after systemic circulatory arrest]
Phrase: of development of neurologic disorders induced by severe hypoxia
Induced genes: neurologic

---

Respiratory function of catecholamines during the late period of avian development
Phrase: increase of plasma catecholamines is induced by hypoxia furthermore treating the
Induced genes: catecholamines

---

Cell inactivation and cell cycle inhibition as induced by extreme hypoxia: the possible role of cell cycle arrest as a protection against hypoxia-induced lethal damage
Phrase: view that the pre-dna-synthetic arrest induced by extreme hypoxia may function
Induced genes: pre-dna-synthetic

---

Relationships between intracellular amino acid levels and protection against injury to isolated proximal tubules
Phrase: tubules from lethal cell injury induced by hypoxia antimycin a or
Induced genes: tubules

---

Hypoxia induces procoagulant activity in cultured human venous endothelium
Phrase: mar;133:428-33 hypoxia induces procoagulant activity in cultured human
Induced genes: procoagulant

---

ECG waveform, short term heart rate variability and plasma catecholamine concentrations in response to hypoxia in intrauterine growth retarded guinea-pig fetuses
Phrase: +/- 35 g hypoxia was induced by letting the doe breathe
Inducers of gene: letting
Inducers of gene: doe
Inducers of gene: breathe

---

[Variations in arrhythmogenic response to catecholamines in acute myocardial ischemia]
Phrase: beta stimulation and potentiated dads induced by alpha stimulation; hypoxia +
Induced genes: dads

---

Preferential feeding behaviour of hens in different gaseous atmospheres
Phrase: carbon dioxide co2 and hypoxia induced by argon which hens could
Inducers of gene: argon
Inducers of gene: hens

---

Endogenous opiates and ventilatory acclimatization to chronic hypoxia in the cat
Phrase: ventilatory response to hypoxia was stimulated by naloxone in the chronically
Inducers of gene: naloxone

---

Delineation of the influence of propionylcarnitine on the accumulation of long-chain acylcarnitines and electrophysiologic derangements evoked by hypoxia in canine myocardium
Phrase: reversal of the electrophysiologic derangements induced by hypoxia in adult canine
Induced genes: electrophysiologic

---

Effects of inhibitors of EDRF and EDHF on vasoreactivity of perfused rat lungs
Phrase: airway hypoxia neither of them inhibited the pulmonary vasodilation to 5
Repressed genes: vasodilation

---

Does the ovine placenta secrete ACTH under normoxic or hypoxic conditions
Phrase: placenta before and during hypoxia induced by the ewe breathing 9-11%
Inducers of gene: ewe
Inducers of gene: 9-11%

---

Role of the inward rectifier IK1 in the myocardial response to hypoxia
Phrase: also attenuated myocardial k loss induced by hypoxia conclusion--our data suggest
Induced genes: myocardial
Induced genes: k

---

[Cell-membrane aspects of the pathogenesis of hypoxia in vibration disease induced by local vibration]
Phrase: of hypoxia in vibration disease induced by local vibration] [article in
Inducers of gene: vibration]
Inducers of gene: [article

---

Lack of correlation between the antiarrhythmic effect of L-propionylcarnitine on reoxygenation-induced arrhythmias and its electrophysiological properties
Phrase: guinea-pig isolated heart; arrhythmias were induced with hypoxia followed by reoxygenation
Inducers of gene: guinea-pig
Inducers of gene: heart;
Inducers of gene: arrhythmias

---

Respiratory, circulatory and neuropsychological responses to acute hypoxia in acclimatized and non-acclimatized subjects
Phrase: contrast to the vasomotor depression induced by central hypoxia which occurred
Induced genes: vasomotor
Induced genes: depression

---

Rapid effects of hypoxia on the cerebrospinal fluid levels of adenosine and related metabolites in newborn and one-month-old piglets
Phrase: 005 in all animals hypoxia induced an increase in csf levels
Induced genes: csf

---

Skin reflectance pulse oximetry: in vivo measurements from the forearm and calf
Phrase: during steady-state hypoxia hypoxia was induced by gradually lowering the inspired
Inducers of gene: lowering
Inducers of gene: inspired
Inducers of gene: lowering
Inducers of gene: inspired

---

Hypoxic contraction in canine basilar arteries: role of endothelium
Phrase: exposure 8 min to hypoxia induced a pronounced contraction that did
Induced genes: contraction

---

Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function
Phrase: adenosine 5'-triphosphate atp placental hypoxia induced by carbon monoxide and other
Inducers of gene: monoxide

---

Effect of hypoxia on endothelium-dependent relaxation of porcine coronary arteries and veins
Phrase: hypoxia but these responses were inhibited during exposure to severe hypoxia
Phrase: by mild hypoxia but was inhibited in the higher concentration range
Repressed genes: hypoxia

---

Lipid peroxidation in neonatal mouse brain subjected to two different types of hypoxia
Phrase: from hypoxia hypoxic stress was induced by 100% nitrogen gas breathing
Inducers of gene: 100%
Inducers of gene: nitrogen
Inducers of gene: gas

---

Effects of cigarette smoking, hypoxia and vasoactive mediators on the production of PGI2 and TXA2 in cultured pulmonary artery endothelial cells
Phrase: of pgi2 in paecs was inhibited by hypoxia or verapamil but
Phrase: not influenced by hypoxia cse inhibited the production of pgi2 in
Phrase: pgi2 during hypoxia might be stimulated by vasoactive mediators produced during
Inducers of gene: vasoactive
Repressed genes: pgi2
Repressed genes: paecs
Repressed genes: pgi2

---

Differential effects of perinatal hypoxia and anoxia on long term seizure susceptibility in the rat
Phrase: the window during which hypoxia induces seizures in the rat ranges
Induced genes: seizures
Induced genes: ranges

---

Postcopulatory myometrial activity in the rat as seen by video-laparoscopy
Phrase: myometrial activity and putative hypoxia induced by seminal constituents may be
Inducers of gene: seminal

---

Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities
Phrase: or of hypoxia plus lactate induces carrier-mediated outward transport of 3h-noradrenaline
Induced genes: carrier-mediated
Induced genes: outward
Induced genes: 3h-noradrenaline

---

Investigational approaches to pulmonary hypertension
Phrase: in which hypertensive pvd was induced by exposure to chronic hypoxia
Induced genes: pvd

---

Protective effect of vitamin E in stagnant hypoxia of the brain
Phrase: laboratory rat to stagnant hypoxia induced by 5xg positive radial acceleration
Inducers of gene: 5xg
Inducers of gene: radial
Inducers of gene: acceleration

---

[Serous retinal detachment in O2 therapy of primary pulmonary hypertension]
Phrase: by the following hypotheses hypoxia induced a dilation of the choroidal
Induced genes: dilation
Induced genes: choroidal

---

Erythropoietin
Phrase: main source of erythropoietin hypoxia stimulates erythropoietin production by a mechanism
Induced genes: erythropoietin

---

Estimation of myocardial perfusion using deuterium nuclear magnetic resonance
Phrase: was infused and hypoxia was induced by increasing the inspired ratio
Inducers of gene: inspired

---

Differences in the hypoxic contraction of small isolated pulmonary arteries of cat and rabbit
Phrase: isolated from the cat hypoxia induced a transient contraction 250 +/-
Induced genes: contraction

---

Effects of hypoxia on the contractions and lactate release induced by high-K
Phrase: lactate release under severe hypoxia induced by 60 mm k+ or
Inducers of gene: k+

---

Influence of hypoxia on adrenergic modulation of triggered activity in isolated adult canine myocytes
Phrase: hypoxia completely abolished the afterdepolarizations induced by alpha-adrenergic stimulation and prevented
Inducers of gene: alpha-adrenergic

---

[Overview of erythropoietin]
Phrase: hepatocytes the epo secretion is stimulated by hypoxia which is detected
Induced genes: hepatocytes

---

Carbon monoxide and lethal arrhythmias
Phrase: the sinus node to acetylcholine induced by hypoxia in both resistant
Induced genes: sinus
Induced genes: acetylcholine

---

On brain protection of co-dergocrine mesylate
Phrase: against moderate and marked hypoxia induced experimentally by inhalation of a
Phrase: volunteers further augmentation of hypoxia induced by inhalation of a gas
Inducers of gene: gas

---

Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary hypertension in lambs
Phrase: by hypoxia during pulmonary hypertension induced by u-46619 atp-mgcl2 001-10 mgkg-1min-1
Phrase: pulmonary circulation during pulmonary hypertension induced either by u-46619 or hypoxia
Inducers of gene: u-46619
Inducers of gene: atp-mgcl2
Inducers of gene: 001-10
Inducers of gene: mgkg-1min-1
Inducers of gene: circulation
Inducers of gene: hypertension

---

Energy demand, supply, and utilization in hypoxia, and force recovery after reoxygenation in rabbit heart muscle
Phrase: creatine compounds after reoxygenation muscles stimulated during hypoxia produce a steady-state
Phrase: found after reoxygenation in muscles stimulated during hypoxia is related to
Inducers of gene: creatine
Inducers of gene: reoxygenation
Inducers of gene: muscles
Inducers of gene: reoxygenation
Inducers of gene: muscles

---

Pulmonary vascular reactivity and permeability to alveolar hypoxia in the dog
Phrase: with autogenous blood hypoxia was induced in the presence coi +
Induced genes: coi

---

Ventilatory responses to hyperkalemia and exercise in normoxic and hypoxic goats
Phrase: by an interaction between exercise induced hyperkalemia and hypoxia plasma potassium
Inducers of gene: exercise

---

Effects of hypoxia on the catecholamine release, Ca2
Phrase: high k+-induced catecholamine release was inhibited by hypoxia to approximately 40%
Phrase: k+-induced increases in [ca2+]i were inhibited by hypoxia to approximately 30%
Phrase: high k+-induced 45ca2+ uptake was inhibited by hypoxia these results suggest
Phrase: these results suggest that hypoxia inhibits high k+-induced catecholamine release and
Repressed genes: k+-induced
Repressed genes: catecholamine
Repressed genes: k+-induced
Repressed genes: [ca2+]i
Repressed genes: k+-induced
Repressed genes: 45ca2+
Repressed genes: uptake
Repressed genes: k+-induced
Repressed genes: catecholamine

---

Acute endothelial swelling is induced in endoneurial microvessels by ischemia
Phrase: there is evidence that hypoxia induces endothelial swelling but this has
Induced genes: swelling

---

Experimental retinal branch vein occlusion in miniature pigs induces local tissue hypoxia and vasoproliferative microangiopathy
Phrase: vein occlusion in miniature pigs induces local tissue hypoxia and vasoproliferative
Inducers of gene: vein
Inducers of gene: miniature
Inducers of gene: pigs

---

Responses of harbor seal and pig heart to progressive and acute hypoxia
Phrase: 1% respectively progressive hypoxia was induced by lowering arterial hemoglobin-oxygen saturation
Inducers of gene: lowering
Inducers of gene: hemoglobin-oxygen

---

Effects of D600 on hypoxic suppression of K
Phrase: this effect indicating hypoxia selectively inhibits the ca2+-activated component of k+
Phrase: hypoxia these drugs also partially inhibited ca2+-independent k+ currents but this
Repressed genes: ca2+-activated
Repressed genes: k+
Repressed genes: ca2+-independent
Repressed genes: k+
Repressed genes: currents

---

Effect of hyperoxia
Phrase: hospital maastricht the netherlands hypoxia inhibits fetal breathing movements but after
Repressed genes: movements

---

Role of vasopressin in mediation of fetal cardiovascular responses to acute hypoxia
Phrase: 8 a 30-minute hypoxia was induced by infusion of nitrogen containing
Phrase: to hypoxia appear to be induced by factors other than arginine
Inducers of gene: infusion
Inducers of gene: nitrogen
Inducers of gene: arginine

---

Influence of phospholipid polyunsatured fatty acid composition on some metabolic disorders induced in rat cardiomyocytes by hypoxia and reoxygenation
Phrase: composition on some metabolic disorders induced in rat cardiomyocytes by hypoxia
Phrase: 09 in sm3 cells hypoxia induced an increase in lactate production
Inducers of gene: composition

---

[Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats]
Phrase: on the pulmonary artery remodeling induced by hypoxia was weaker than
Phrase: prevented primarily pulmonary artery remodeling induced by hypoxia and t inhibited
Phrase: induced by hypoxia and t inhibited mainly hypoxic pulmonary vasoconstriction response
Repressed genes: hypoxic
Repressed genes: vasoconstriction

---

[Effect of captopril on the activities of angiotensin II and angiotensin converting enzyme during hypoxia induced pulmonary hypertension]
Phrase: angiotensin converting enzyme during hypoxia induced pulmonary hypertension] [article in chinese]
Phrase: in the development of hypoxia induced pulmonary hypertension nine pigs 50
Phrase: a part in acute hypoxia induced pulmonary hypertension and captopril inhibits
Induced genes: hypertension]
Induced genes: [article
Induced genes: hypertension
Induced genes: pigs
Induced genes: hypertension
Induced genes: captopril

---

Depression of ventilatory responses to hypoxia and hypercapnia after pentamorphone
Phrase: hypercapnia and isocapnic hypoxia were induced through a rebreathing method during
Induced genes: rebreathing

---

Comparison of cardiorespiratory responses to sudden progressive hypoxia in an animal model with and without respiratory failure
Phrase: man acute progressive hypoxia was induced by rebreathing through a respirometer
Inducers of gene: rebreathing
Inducers of gene: respirometer

---

Protective effect of DM-9384, a novel pyrrolidone derivative, against experimental cerebral anoxia
Phrase: in lactate and lactate/pyruvate ratio induced by hypoxia in rats the
Induced genes: lactate/pyruvate

---

Responses of type I cells dissociated from the rabbit carotid body to hypoxia
Phrase: the carotid body chemoreceptors are stimulated in situ by hypoxia we
Inducers of gene: chemoreceptors

---

Hypoxically inducible barley lactate dehydrogenase: cDNA cloning and molecular analysis
Phrase: barley and other cereals hypoxia induces a set of five isozymes
Induced genes: isozymes

---

[Modification of physical fitness of patients with coronary heart disease with nifedipine during a stay at altitude]
Phrase: and at conditions of altitude induced hypoxia 9000 ft above sea
Inducers of gene: altitude

---

The effect of passage number on the stimulation by hypoxia of growth and sprouting activity in cultured aortic endothelium from the rat
Phrase: passages the degree of sprouting stimulated by hypoxia remained constant for
Induced genes: sprouting

---

Theophylline stimulates fetal breathing movements during hypoxia
Phrase: aug;282:83-6 theophylline stimulates fetal breathing movements during hypoxia
Inducers of gene: aug;282:83-6
Inducers of gene: theophylline

---

Oxygen and substrate deprivation on isolated rat cardiac myocytes: temporal relationship between electromechanical and biochemical consequences
Phrase: rate in substrate-free conditions hypoxia induced a gradual decline in plateau
Induced genes: gradual
Induced genes: plateau

---

A comparison of the techniques of alkaline filter elution and alkaline sucrose sedimentation used to assess DNA damage induced by 2-nitroimidazoles
Phrase: conditions whereas incubation with misonidazole induces dna-ssb only under hypoxia the
Inducers of gene: misonidazole

---

Direct embryotoxicity of cocaine in rats: effects on mitochondrial activity, cardiac function, and growth and development in vitro
Phrase: meet the increased glucose demands induced by hypoxia the developmental toxicity
Induced genes: demands

---

Effects of systemic hypoxia on the distribution of cardiac output in the rat
Phrase: unanaesthetized and anaesthetized rats hypoxia induced pronounced increases in vascular conductance
Induced genes: conductance

---

Endogenous adenosine enhances vagal negative chronotropic effect during hypoxia in the anaesthetised rabbit
Phrase: adenosine receptor blockade hypoxia was induced by lowering oxygen content of
Phrase: play a role in hypoxia induced bradycardia and vagal potentiation
Induced genes: bradycardia
Induced genes: vagal
Induced genes: potentiation
Inducers of gene: lowering

---

Brain glutamate metabolism during hypoxia and peripheral chemodenervation
Phrase: after 1 h of hypoxia induced with 10 or 12% o2
Induced genes: 12%
Induced genes: o2

---

Atrial natriuretic factor in hydrops fetalis caused by Rh isoimmunisation
Phrase: of atrial natriuretic factor release induced by hypoxia
Induced genes: atrial
Induced genes: natriuretic

---

Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia
Phrase: pressure thirty minutes of hypoxia stimulated endothelin release by 71 +/-
Induced genes: endothelin

---

[Effects of acute hypoxia on the development of corazol-induced seizures]
Phrase: of corazol dose acute hypoxia inhibits development of seizures: decreases the
Repressed genes: seizures:

---

Leukotrienes and prostaglandins in fetal lung liquid
Phrase: level of acute hypoxia was induced to decrease fetal arterial po2
Induced genes: po2

---

Alterations of intercellular junctions induced by hypoxia in canine myocardium
Phrase: alterations of intercellular junctions induced by hypoxia in canine myocardium
Phrase: mechanisms of impaired cell coupling induced by hypoxia in canine myocardium
Phrase: determinants of progressive cellular uncoupling induced by hypoxia
Induced genes: intercellular
Induced genes: junctions
Induced genes: coupling

---

Effects of dopexamine hydrochloride on hypoxic pulmonary vasoconstriction in isolated rat lung
Phrase: hypoxia we conclude that dopexamine inhibits hpv and vasodilates the pulmonary
Repressed genes: vasodilates

---

[Chemoreceptor modulation of the respiratory reactions during muscle contractions in the cat]
Phrase: of the hindlimb muscles were induced in hypercapnia hypoxia and hyperoxia
Inducers of gene: hindlimb
Inducers of gene: muscles

---

Hypoxia and CCl4-induced liver injury, but not acidosis, impair metabolism of cysteinyl leukotrienes in perfused rat liver
Phrase: the omega-oxidized products hypoxia also inhibited the biliary excretion of radioactivity
Repressed genes: biliary
Repressed genes: excretion
Repressed genes: radioactivity

---

Bioreductive drugs and the selective induction of tumour hypoxia
Phrase: this work tumour hypoxia is induced by physically occluding the tumour
Inducers of gene: occluding

---

Inhibition of glucose-regulated and heat shock protein induction by low temperature
Phrase: certain oxygen-regulated proteins were still induced by hypoxia at 25 degrees
Induced genes: oxygen-regulated

---

Effects of neuropeptide Y and calcitonin gene-related peptide on sheep coronary artery rings under oxygenated, hypoxic and simulated myocardial ischaemic conditions
Phrase: reduced the contraction that was induced by hypoxia and simulated ischaemia
Induced genes: contraction

---

Brain blood flow and ventilatory response to hypoxia in sedated newborn piglets
Phrase: after 10 min of hypoxia induced by breathing 10% o2 two
Inducers of gene: 10%
Inducers of gene: o2

---

Glutathione disulfide as index of oxidant stress in rat liver during hypoxia
Phrase: of sulfobromophthalein and 1-chloro-24-dinitrobenzene hypoxia inhibited s-conjugate excretion through both pathways
Phrase: under normoxia hypoxia reduced the stimulated gssg export by 38 tbhp
Induced genes: gssg
Induced genes: tbhp
Repressed genes: s-conjugate
Repressed genes: excretion

---

Effect of Plasmodium yoelii infection on GABA metabolism of mouse brain
Phrase: may be due to hypoxia induced by malarial infection
Inducers of gene: malarial

---

Differential effects of hypoxia upon contractions evoked by potassium and noradrenaline in rabbit arteries in vitro
Phrase: that the inhibition of contraction induced by hypoxia is not simply
Induced genes: contraction

---

The effect of repeated intermittent hypoxia on pulmonary vasoconstriction in the newborn
Phrase: at the end hypoxia uniformly induced pulmonary vasoconstriction repeated intermittent hypoxic
Induced genes: vasoconstriction
Induced genes: intermittent
Induced genes: hypoxic

---

Neuropeptide Y is released together with noradrenaline from the human heart during exercise and hypoxia
Phrase: findings suggest that arterial hypoxia stimulates cardiac npy together with na
Induced genes: cardiac
Induced genes: npy

---

Brain plasticity after damage
Phrase: and long-term effects of hypoxia induced by clamping the rat's umbilical
Inducers of gene: clamping
Inducers of gene: rat's
Inducers of gene: umbilical

---

Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis
Phrase: erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis
Repressors of gene: acidosis

---

Cultured neurons for testing antihypoxic drug effects
Phrase: under hypoxic conditions hypoxia was induced by addition of sodium cyanide
Inducers of gene: sodium
Inducers of gene: cyanide

---

Megakaryocytopoiesis in experimentally induced chronic normobaric hypoxia
Phrase: megakaryocytopoiesis in experimentally induced chronic normobaric hypoxia
Inducers of gene: megakaryocytopoiesis

---

Different responses of CA1 and CA3 regions to hypoxia in rat hippocampal slice
Phrase: 85 mm [k+]o hypoxia was induced by switching the overflow gas
Inducers of gene: switching
Inducers of gene: overflow
Inducers of gene: gas

---

Metabolic effects of exposure to hypoxia plus cold at rest and during exercise in humans
Phrase: 8 degrees c nc; hypoxia induced by breathing 12% o2 in
Inducers of gene: 12%
Inducers of gene: o2

---

Upper airway muscle and diaphragm responses to hypoxia in the piglet
Phrase: by 10 min hypoxia also stimulated all three upper airway muscles
Phrase: chemoreceptor stimulation and/or central disinhibition induced by hypoxia preferentially influence those
Induced genes: airway
Induced genes: muscles
Induced genes: chemoreceptor
Induced genes: disinhibition

---

Ventilatory effects of almitrine bismesilate in dogs breathing normoxic, hyperoxic and hypoxic mixtures
Phrase: ventilatory response to hypoxia almitrine stimulated ventilation irrespective of the level
Induced genes: ventilation

---

[Prevention of hypoxic pulmonary hypertension with
Phrase: contractility of right ventricle were induced by hypoxia without significant change
Induced genes: contractility
Induced genes: right

---

Regulation of capillary blood flow and oxygen supply in skeletal muscle in dogs during hypoxaemia
Phrase: 3 stepwise hypoxaemia hypoxic hypoxia induced an increasing discrepancy between capillary
Induced genes: capillary

---

Forms of soluble iron in mouse stomach and duodenal lumen: significance for mucosal uptake
Phrase: adaptive enhancement of fe absorption induced by chronic hypoxia electron paramagnetic
Induced genes: absorption

---

Does leukotriene C4 mediate hypoxic vasoconstriction in isolated ferret lungs
Phrase: hypoxia at 100 microgram/ml fpl55712 inhibited the responses to ltc4 and
Repressed genes: ltc4

---

Effect of postnatal hypoxia on ammonia metabolism during the early neonatal period in the rat
Phrase: these results suggest that hypoxia inhibited ureogenesis by decreasing the ammonia
Repressed genes: ureogenesis
Repressed genes: ammonia

---

MIBG scintigraphic assessment of cardiac adrenergic activity in response to altitude hypoxia
Phrase: creteil france high altitude hypoxia induces a decrease in the cardiac
Induced genes: cardiac

---

Effect of chronic in vivo exposure to hypoxia on serotonin uptake by isolated rats lungs
Phrase: shown that exposure to hypoxia stimulates serotonin uptake by cultured bovine
Induced genes: serotonin
Induced genes: uptake

---

Mucosal blood flow stasis and hypoxemia as the pathogenesis of acute gastric mucosal injury: role of endogenous leukotrienes and prostaglandins
Phrase: the mucosal congestion and hypoxia induced by 40% ethanol the pretreatment
Inducers of gene: 40%
Inducers of gene: ethanol

---

Oxygen and diabetic eye disease
Phrase: wise suggested that retinal hypoxia stimulated retinal neovascularization in the ischemic
Induced genes: retinal
Induced genes: neovascularization

---

Effect of cyclic guanosine monophosphate on hypoxic and angiotensin-II-induced pulmonary vasoconstriction
Phrase: of cgmp on pulmonary vasoconstriction induced by either alveolar hypoxia or
Induced genes: cgmp
Induced genes: vasoconstriction

---

Breathing of phrenicotomized rats
Phrase: doses of pentobarbital breathing was stimulated by hypoxia and hypercapnia due
Induced genes: pentobarbital

---

Plasma aldosterone concentration during hypoxia, stimulated hyperglycaemia and when protein synthesis is blocked with actinomycin D
Phrase: plasma aldosterone concentration during hypoxia stimulated hyperglycaemia and when protein synthesis
Induced genes: hyperglycaemia

---

External intercostal muscle activity during acute hypoxia in the kitten
Phrase: intercostal muscles acute hypoxia was induced by the animals breathing 13%
Inducers of gene: 13%

---

[Respiratory effects of almitrine on various levels of the fraction of inspired oxygen
Phrase: depressed ventilation -21% whilst hypoxia stimulated it +126% although significantly less
Induced genes: +126%

---

Shivering and cardiorespiratory responses during normocapnic hypoxia in the pigeon
Phrase: indicative of shivering thermogenesis was inhibited during hypoxia and body temperature
Repressors of gene: shivering
Repressors of gene: thermogenesis

---

Towards a mouse model for sickle cell disease: HB SAD
Phrase: hb during development finally hypoxia induces a high mortality in sad
Induced genes: sad

---

Effects of isoprenaline, adrenaline and selective alpha 1- and alpha 2- adrenoceptor stimulation on hypoxic pulmonary vasoconstriction in rat isolated perfused lungs
Phrase: with blood in situ vasoconstriction induced by hypoxia was reversed by
Induced genes: vasoconstriction

---

Sympathetic peripheral chemoreflex is independent of expiratory output neurons in the cat
Phrase: following observations 1 hypoxia often inhibited iicen activity while the pn
Repressed genes: iicen

---

[Electrophysiological studies of acute anoxic hypoxia]
Phrase: ventilation acute anoxic hypoxia was induced by apnea with abrupt cessation
Phrase: after hypoxia experimental hypoxia was induced initially for 3 minutes and
Inducers of gene: apnea

---

Glucose-6-phosphate dehydrogenase activity in CaNT tumours of different volume and response to tumour clamping and X-irradiation
Phrase: increasing relation was found artificially induced tumour hypoxia resulting from 15
Inducers of gene: artificially

---

Stimulus-activated changes in brain tissue temperature in the anesthetized rat
Phrase: few tenths degree centigrade vasodilation induced by hypercapnia or hypoxia caused
Induced genes: tenths
Induced genes: centigrade
Induced genes: vasodilation

---

Barbiturates protect retinal cells from hypoxia in cell culture
Phrase: mammalian retinal cells from damage induced by hypoxia using a special
Induced genes: retinal

---

Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia
Phrase: this moderate degree of hypoxia inhibited p less than 005 endothelium-dependent
Repressed genes: p
Repressed genes: endothelium-dependent

---

[Effects of prostacyclin
Phrase: induced with hpv while pgi2 induces hypoxia by inhibiting hpv response
Inducers of gene: pgi2

---

Correlative contribution of carotid and aortic afferences to the ventilatory chemosensory drive in steady-state normoxia and to the ventilatory chemoreflexes induced by transient hypoxia
Phrase: and to the ventilatory chemoreflexes induced by transient hypoxia
Induced genes: ventilatory
Induced genes: chemoreflexes

---

Cardiovascular response to acute airway obstruction and hypoxia
Phrase: hypoxia magnifies the cardiovascular changes induced by acute expiratory resistive loads
Inducers of gene: expiratory
Inducers of gene: resistive
Inducers of gene: loads

---

The sequence of cellular and hemodynamic changes of chronic pulmonary hypertension induced by hypoxia and other stimuli
Phrase: changes of chronic pulmonary hypertension induced by hypoxia and other stimuli
Induced genes: hypertension

---

Responses of isolated guinea pig pulmonary venules to hypoxia and anoxia
Phrase: anoxia are similar to those induced by hypoxia in vivo and
Induced genes: anoxia

---

Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts
Phrase: effect of the increased adenosine induced by hypoxia and 2 under
Induced genes: adenosine

---

Effect of ligustrazine on pulmonary vascular changes induced by chronic hypoxia in rats
Phrase: ligustrazine on pulmonary vascular changes induced by chronic hypoxia in rats
Induced genes: ligustrazine

---

Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung
Phrase: of the change in chemiluminescence induced by hypoxia and the strength
Induced genes: chemiluminescence

---

[Advanced research in hypoxic cells]
Phrase: hypoxia at subcellular level hypoxia induces specific protein while hypoxia inhibits
Phrase: induces specific protein while hypoxia inhibits initiation of dna replication radioresistant
Induced genes: hypoxia
Induced genes: hypoxia

---

Beta-adrenoceptor agonists and hypoxia in sheep fetuses
Phrase: served as controls hypoxia was induced by intermittent complete occlusions of
Inducers of gene: intermittent
Inducers of gene: occlusions

---

Autonomic nerve and cardiovascular responses to changing blood oxygen and carbon dioxide levels in the rat
Phrase: artificially ventilated rats systemic hypoxia induced a co-activation of two antagonistic
Induced genes: co-activation

---

Biochemical studies on the release of catecholamines from the rat carotid body in vitro
Phrase: type both hypoxia and carbachol stimulated the release of 45ca from
Induced genes: 45ca

---

Atrial bioenergetic variations in moderate hypoxia: danger or protective defense
Phrase: different degrees of hypoxia were induced by lowering oxygen tension from
Phrase: moderate hypoxia 40% o2 which induced a significant decrease of contractile
Induced genes: contractile
Inducers of gene: lowering
Inducers of gene: tension

---

Respiratory activities of intralaryngeal branches of the recurrent laryngeal nerve
Phrase: enhanced by hypercapnia and often inhibited by hypoxia the results are
Repressed genes: hypercapnia

---

Endothelium-derived relaxing and contracting factors: potential role in coronary artery disease
Phrase: hypertension reduce endothelium-dependent relaxations hypoxia inhibits the release of edrf and
Repressed genes: edrf

---

Atrial natriuretic peptide protects hepatocytes against damage induced by hypoxia and reactive oxygen
Phrase: peptide protects hepatocytes against damage induced by hypoxia and reactive oxygen
Induced genes: hepatocytes

---

Role of lipoxygenase, cyclooxygenase and cytochrome P-450 metabolites in contractions of isolated guinea pig pulmonary venules induced by hypoxia and anoxia
Phrase: isolated guinea pig pulmonary venules induced by hypoxia and anoxia
Phrase: did not alter venular contractions induced by hypoxia or anoxia contractions
Induced genes: guinea
Induced genes: pig
Induced genes: venules
Induced genes: venular
Induced genes: contractions

---

Effect of regional alveolar hypoxia on gas exchange in dogs
Phrase: we conclude that flow diversion induced by regional alveolar hypoxia preserves
Induced genes: diversion

---

Role of adenosine in hypoxic ventilatory depression
Phrase: adenosine in the ventilatory depression induced by hypoxia was studied in
Induced genes: adenosine
Induced genes: ventilatory
Induced genes: depression

---

Contribution of S-adenosylhomocysteine to cardiac adenosine formation
Phrase: not significantly alter the hypoxia induced adenosine release since all experiments
Phrase: adenosine kinase 3 the hypoxia induced adenosine production is predominantly derived
Induced genes: adenosine
Induced genes: adenosine

---

Intestinal blood flow and oxygen consumption: responses to hemorrhage in the developing piglet
Phrase: greater risk for tissue hypoxia induced by arterial hemorrhage than that
Inducers of gene: hemorrhage

---

The radiation response of cells recovering after chronic hypoxia
Phrase: hypoxic treatment although growth inhibition induced by 12 h of hypoxia
Induced genes: hypoxic

---

Cardiopulmonary function in exercising bar-headed geese during normoxia and hypoxia
Phrase: unaltered 2 hypoxia at rest stimulated ventilation to rise but not
Phrase: 3 exercise during hypoxia further stimulated ventilation resulting in elevated arterial
Induced genes: ventilation
Induced genes: ventilation

---

Modulation of prostaglandin biosynthesis in hypoxic murine mammary adenocarcinoma cells by misonidazole
Phrase: the suspended cells under hypoxia induced by flushing sealed vials with
Phrase: of hypoxia pg formation was inhibited by 50% indomethacin was able
Inducers of gene: flushing
Inducers of gene: sealed
Inducers of gene: vials
Repressors of gene: 50%
Repressors of gene: indomethacin

---

O2-supply to the kidneys and the production of erythropoietin
Phrase: rats exposed to hypobaric hypoxia stimulated altitude of 6000 m for
Induced genes: altitude
Induced genes: m

---

Effects of hypoxia on metabolic rate of conscious adult cats during cold exposure
Phrase: components of cold-induced vo2 hypoxia induced by co fico = 0002
Inducers of gene: co
Inducers of gene: fico
Inducers of gene: =

---

Synergistic enhancement of the efficacy of the bioreductively activated alkylating agent RSU-1164 in the treatment of prostatic cancer by photodynamic therapy
Phrase: reduction to become cytotoxic hypoxia induces a massive increase in reductive
Induced genes: reductive

---

Effect of magnesium on depression of the monosynaptic reflex induced by 2-chloroadenosine or hypoxia in the isolated spinal cord of neonatal rats
Phrase: depression of the monosynaptic reflex induced by 2-chloroadenosine or hypoxia in
Induced genes: depression
Induced genes: monosynaptic
Induced genes: reflex

---

ABR threshold is a function of blood oxygen level
Phrase: are probably due to hypoxia induced depression of the endocochlear potential
Induced genes: depression
Induced genes: endocochlear

---

Protective action of YM-12617, an alpha 1-adrenoceptor antagonist, on the hypoxic and reoxygenated myocardium
Phrase: the heart were examined hypoxia induced several pathophysiological changes upon subsequent
Induced genes: pathophysiological

---

Induction of tumour hypoxia by a vasoactive agent
Phrase: of anaesthesia prolongs the hypoxia induced by hydralazine
Inducers of gene: hydralazine

---

Hypoxia induced pulmonary edema--a case report
Phrase: jun;272:185-9 hypoxia induced pulmonary edema--a case report
Induced genes: edema--a

---

Enhancement of the pulmonary vasoconstriction reaction to alveolar hypoxia in systemic high blood pressure
Phrase: of hypocapnia and respiratory alkalosis induced by hypoxia and plasma catecholamines
Induced genes: hypocapnia
Induced genes: alkalosis

---

Hypoxia stimulates release of endothelium-derived relaxant factor
Phrase: 2:h1595-600 hypoxia stimulates release of endothelium-derived relaxant factor
Phrase: it was tested whether hypoxia stimulates the release of endothelium-derived relaxant
Phrase: kept above 300 mmhg hypoxia induced a dilation of 11 +/-
Phrase: these results suggest that hypoxia stimulates the release of edrf from
Induced genes: endothelium-derived
Induced genes: relaxant
Induced genes: endothelium-derived
Induced genes: relaxant
Induced genes: dilation
Induced genes: edrf

---

Beneficial effect of amosulalol and phentolamine on post-hypoxic recovery of contractile force and energy metabolism in rabbit hearts
Phrase: of the rabbit 2 hypoxia induced cessation of cardiac contractile force
Induced genes: cardiac
Induced genes: contractile
Induced genes: force

---

Hypoxia stimulates endothelial cell angiotensin-converting enzyme antigen synthesis
Phrase: 1:c1231-8 hypoxia stimulates endothelial cell angiotensin-converting enzyme antigen
Induced genes: angiotensin-converting

---

Corneal hydration control in Fuchs
Phrase: corneal thickness recovery from swelling induced by hypoxia or following overnight
Induced genes: corneal
Induced genes: thickness
Induced genes: swelling

---

Effects of hypoxia on noradrenaline release and neuronal reuptake in isolated rabbit thoracic aortic strips
Phrase: these results show that hypoxia inhibits both noradrenaline release evoked by
Repressed genes: noradrenaline
Repressed genes: evoked

---

Protective effect of idebenone against hypoxia in mice
Phrase: of mice subjected to hypoxia induced by n2 and co2 inhalation
Inducers of gene: n2
Inducers of gene: co2

---

Noninvasive oximetry in the rat
Phrase: fall in sao2 during hypoxia induced by hypobaric decompression or decreasing
Inducers of gene: hypobaric
Inducers of gene: decompression

---

Enhancement of the anti-tumor effect of melphalan in experimental mice by some vaso-active agents
Phrase: after melphalan hydralazine 5 mg/kg induces close to 100% radiobiological hypoxia
Inducers of gene: hydralazine

---

Almitrine inhibits breathing movements in fetal sheep in utero
Phrase: of reading whiteknights whilst hypoxia stimulates fetal peripheral chemoreceptors fetal breathing
Induced genes: chemoreceptors

---

Polymyxin B inhibits stimulation of glucose transport in muscle by hypoxia or contractions
Phrase: increase in sugar transport activity induced by insulin and hypoxia it
Induced genes: sugar

---

Role of endothelium in hypoxic contraction of canine basilar artery
Phrase: contractions caused by hypoxia were inhibited by pretreatment with adenosine or
Repressors of gene: adenosine

---

The effect of alkalosis on hypoxia-induced pulmonary vasoconstriction in lungs of newborn rabbits
Phrase: metabolic alkalosis when alkalosis was induced during hypoxia when respiratory or
Phrase: respiratory or metabolic alkalosis was induced before hypoxia the magnitude of
Inducers of gene: alkalosis
Inducers of gene: alkalosis
Inducers of gene: alkalosis

---

Some effects of fructose-1,6-diphosphate on rat myocardial tissue related to a membrane-stabilizing action
Phrase: and conditions of chemical hypoxia induced by kcn and iodoacetate the
Inducers of gene: kcn
Inducers of gene: iodoacetate

---

Enhanced inositol trisphosphate response to alpha 1-adrenergic stimulation in cardiac myocytes exposed to hypoxia
Phrase: x 10-8 m hypoxia also induced a 100-fold reduction in the
Induced genes: 100-fold

---

Plasma levels of atrial natriuretic peptide under acute hypoxia in normal subjects
Phrase: level was observed severe hypoxia induced by 10% o2 breathing increased
Inducers of gene: 10%
Inducers of gene: o2

---

Effects of peripheral and central chemoreflex activation on the isopnoeic rating of breathing in exercising humans
Phrase: of both peripheral chemoreflex activation induced by isocapnic hypoxia and central
Phrase: hypoxia and central chemoreflex activation induced by hypercapnic hyperoxia on the
Induced genes: chemoreflex
Inducers of gene: hypercapnic

---

Do inhibitors of lipoxygenase and cyclooxygenase block neonatal hypoxic pulmonary vasoconstriction
Phrase: that of hypoxia was completely inhibited we conclude that thromboxanes are
Repressed genes: thromboxanes

---

Cellular K
Phrase: in which glycolysis is not inhibited eg hypoxia k+ efflux does
Repressors of gene: glycolysis

---

Hypoxic and hypercapnic responses of [Ca2
Phrase: electrodes have shown that hypoxia induced a decrease in [ca2+]o of
Phrase: ouabain inhibited the [k+]o undershoot induced by hypoxia as did the
Phrase: ca2+ and k+ ions concentration induced by hypoxia and hypercapnia represent
Induced genes: [ca2+]o
Induced genes: ouabain
Induced genes: [k+]o
Induced genes: undershoot
Induced genes: k+

---

Deleterious effect of ouabain on myocardial function during hypoxia
Phrase: decrease in diastolic ventricular distensibility induced by hypoxia worsens the decline
Induced genes: diastolic
Induced genes: distensibility

---

Effects of isobaric hypoxia on murine medullary and splenic megakaryocytopoiesis
Phrase: of tennessee knoxville 37901-1071 hypoxia stimulates erythropoiesis and inhibits megakaryocytopoiesis in
Phrase: 37901-1071 hypoxia stimulates erythropoiesis and inhibits megakaryocytopoiesis in the bone marrow
Induced genes: erythropoiesis
Induced genes: megakaryocytopoiesis
Repressed genes: megakaryocytopoiesis

---

[Quantitative and qualitative changes in protein biosynthesis induced by hypoxia and transplantation of embryonic nerve tissue into the brain of adult mammals]
Phrase: qualitative changes in protein biosynthesis induced by hypoxia and transplantation of
Induced genes: qualitative

---

Effect of hypoxia upon the growth and sprouting activity of cultured aortic endothelium from the rat
Phrase: there were controls hypoxia also stimulated sprouting activity to occur earlier
Induced genes: sprouting

---

Studies of embryotoxic mechanisms of niridazole: evidence that oxygen depletion plays a role in dysmorphogenicity
Phrase: we concluded that the hypoxia induced by redox cycling of ndz
Inducers of gene: ndz

---

Effects of hypoxia and hypercapnia on atrial natriuretic factor and plasma renin activity in conscious dogs
Phrase: 5 hypercapnia but not hypoxia induced an increase in left atrial
Induced genes: atrial

---

Isocapnic hypoxemia and neuropsychological functioning
Phrase: differences in co2 levels during induced hypoxia these variables should be
Inducers of gene: co2

---

Electrophysiologic alterations produced by hypoxia in the canine heart
Phrase: left ventricle lv during hypoxia induced by either hypoventilation or by
Phrase: 109% to 121% during hypoxia induced by both methods hypoventilatory hypoxia
Induced genes: 109%
Induced genes: 121%
Inducers of gene: hypoventilation
Inducers of gene: hypoventilatory
Inducers of gene: hypoxia

---

Role of adenosine in cerebral hypoxic hyperemia in the unanesthetized rabbit
Phrase: each cerebral region the vasodilatation induced by hypoxia was significantly decreased
Induced genes: vasodilatation

---

No significant overreplication occurs in Ehrlich ascites cells during and after reversal of hypoxia
Phrase: examine whether transient controlled hypoxia induces significant overreplication in the dna
Induced genes: overreplication

---

Surgical correction of venous incompetence restores normal skin blood flow and abolishes skin hypoxia during exercise
Phrase: the veins by venous distention induces reflex vasoconstriction and hypoxia in
Inducers of gene: veins
Inducers of gene: venous
Inducers of gene: distention

---

Enhanced hypoxic pulmonary vasoconstriction in hypertension
Phrase: or hypocapnia and respiratory alkalosis induced by hypoxia and probably was
Induced genes: hypocapnia
Induced genes: alkalosis

---

Hypoxia-induced dysfunctions and injury of astrocytes in primary cell cultures
Phrase: of hypoxia glutamate uptake was inhibited 80% by similar hypoxic conditions
Repressed genes: 80%
Repressed genes: hypoxic

---

The effects of fasting or hypoxia on rates of protein synthesis in vivo in subcellular fractions of rat heart and gastrocnemius muscle
Phrase: ratios in the heart fasting inhibited protein synthesis but moderate hypoxia
Repressors of gene: fasting

---

Pulmonary vascular responses to surgical chemodenervation and chemical sympathectomy in dogs
Phrase: hypoxia so that hpv was inhibited almitrine had these same pulmonary
Repressed genes: almitrine

---

Direct adrenal medullary catecholamine response to hypoxia in fetal sheep
Phrase: to 30 min of hypoxia induced by perfusing with krebs-henseleit solution
Inducers of gene: perfusing
Inducers of gene: krebs-henseleit
Inducers of gene: solution

---

Effect of pyritinol on the dopaminergic system and behavioural outcome in an animal model of mild chronic postnatal hypoxia
Phrase: hypoxia and decreases the potassium stimulated da release from striatal slices
Induced genes: striatal
Induced genes: slices

---

Effect of mild postnatal hypoxia and L-dopa administration on dopamine concentration in striata of the newborn rat and long term sequelae on dopamine turnover
Phrase: gdr mild chronic postnatal hypoxia induces a long-lasting increase of da
Induced genes: long-lasting

---

Contribution to some radiobiological aspects of the investigation of chemical radiosensitizers of hypoxic cells
Phrase: in the rubber cuff the induced hypoxia of bone marrow demonstrated
Phrase: proportional to the degree of induced bone marrow hypoxia during irradiation
Inducers of gene: rubber
Inducers of gene: cuff

---

Vasodilator actions of flunarizine in isolated dog cerebral and extracerebral arteries
Phrase: and severe hypoxia and then stimulated by pgf2 alpha and ca2+
Inducers of gene: pgf2

---

Prostacyclin as a cerebroprotective agent against brain hypoxia
Phrase: hypovolemic hypoxia in cats pgi2 induced a dose-dependent prolongation of the
Induced genes: prolongation

---

Alterations in rat carbohydrate metabolism induced by canatoxin as a probable consequence of primary hypoxia
Phrase: isolated from canavalia ensiformis seeds induces hypoxia and hyperglycemia in male
Inducers of gene: canavalia
Inducers of gene: ensiformis
Inducers of gene: seeds

---

Pulmonary vasodilator action of ligustrazine, active principle of a traditional Chinese remedy, in rats and ferrets
Phrase: to angiotensin ii ligustrazine preferentially inhibited the vasoconstriction caused by hypoxia
Repressors of gene: angiotensin
Repressors of gene: ligustrazine

---

Pulmonary blood vessels and endocrine cells in subacute infantile mountain sickness
Phrase: arterioles thought to have been induced by hypobaric hypoxia in addition
Induced genes: arterioles

---

[The role of lipoxygenase and cyclooxygenase metabolites in acute hypoxic pulmonary vasoconstriction in piglets]
Phrase: found that acute alveolar hypoxia induced remarkable pulmonary vasoconstriction associated with
Induced genes: vasoconstriction

---

Convulsions induced by canatoxin in rats are probably a consequence of hypoxia
Phrase: the seeds of canavalia ensiformis induces lipoxygenase-dependent hypoxia and sex-related alterations
Inducers of gene: seeds
Inducers of gene: canavalia
Inducers of gene: ensiformis

---

Hypoxia and hypercapnia increase the sympathoadrenal medullary functions in anesthetized, artificially ventilated rats
Phrase: it is concluded that hypoxia stimulates the adrenal medulla via the
Induced genes: adrenal
Induced genes: medulla

---

Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia
Phrase: mice from the learning impairment induced by hypoxia neither beta-alanine nor
Phrase: against the onset of convulsions induced by hypoxia while convulsions induced
Phrase: induced by hypoxia while convulsions induced by pentylenetetrazole ptz and hyperbaric
Induced genes: learning
Induced genes: convulsions
Inducers of gene: pentylenetetrazole
Inducers of gene: ptz
Inducers of gene: hyperbaric

---

Neuronal and glial responses to hypoxia and hypercapnia
Phrase: frg changes of membrane properties induced by hypoxia and hypercapnia and/or
Induced genes: frg

---

Brain hypoxia preferentially stimulates genioglossal EMG responses to CO2
Phrase: brain hypoxia preferentially stimulates genioglossal emg responses to co2
Induced genes: genioglossal
Induced genes: emg
Induced genes: co2

---

[Effect on erythropoietin production after inhibition of RNA synthesis by D-actinomycin and hyperglycemia]
Phrase: using automatic scintillation gamma-counter hypoxia induced an increase of plasma erythropoietin
Induced genes: erythropoietin

---

Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
Phrase: dec;8524:9533-7 hypoxia induces dna overreplication and enhances metastatic
Phrase: confirmed that hypoxia and reoxygenation induced cell cycle perturbations and dna
Induced genes: overreplication

---

Phosphoinositide metabolism and metabolism-contraction coupling in rabbit aorta
Phrase: of nor-induced force was markedly inhibited during hypoxia to 40-50% of
Repressors of gene: nor-induced
Repressors of gene: force

---

Short-term effects of altered shell conductance on oxygen uptake and hematological variables of late chicken embryos
Phrase: hypoxia due to decreased go2 induced erythropoiesis in 18-19-day embryos but
Induced genes: erythropoiesis
Induced genes: 18-19-day

---

Chronic hypoxia induces selective maldevelopment of peripheral myelin in rat
Phrase: chronic hypoxia induces selective maldevelopment of peripheral myelin
Induced genes: maldevelopment
Induced genes: myelin

---

Fetal hypoxia elevates plasma atrial natriuretic factor concentration
Phrase: fetal blood volume hypoxia was induced in chronically catheterized sheep fetuses
Induced genes: catheterized
Induced genes: sheep
Induced genes: fetuses

---

Proton conductance caused by long-chain fatty acids in phospholipid bilayer membranes
Phrase: eg in ischemia hypoxia hormonally induced lipolysis or certain hereditary disorders
Induced genes: lipolysis

---

Stimulation of breathing movements by L-5-hydroxytryptophan in fetal sheep during normoxia and hypoxia
Phrase: 3 in hypoxia l-5-htp similarly stimulated fbm this effect was also
Induced genes: fbm

---

Different inhibition by vasodilators of coronary artery contraction
Phrase: severe hypoxia in the strips stimulated by pgf2 alpha the contraction
Phrase: contraction under hypoxia pgi2 analogues inhibited the contraction due to reoxygenation
Inducers of gene: pgf2
Inducers of gene: contraction
Repressed genes: contraction
Repressed genes: reoxygenation

---

Lactate in fetal tissue during hypoxia
Phrase: guinea-pig fetuses acute hypoxia was induced by anaesthesia operative stress and
Inducers of gene: anaesthesia

---

Protective effect of hypoxia in the ram testis during single and split-dose X-irradiation
Phrase: and hypoxic conditions hypoxia was induced by inflation of an occluder
Inducers of gene: inflation
Inducers of gene: occluder

---

[Blood supply of free skin flaps]
Phrase: the recipient site which is stimulated by the relative hypoxia of
Induced genes: recipient

---

Cultured neurons for testing cerebroprotective drug effects in vitro
Phrase: cerebroprotective drug effects hypoxia was induced by adding 1 mmol/l kcn
Inducers of gene: adding
Inducers of gene: mmol/l
Inducers of gene: kcn

---

Postirradiation modification of tumor blood flow: a method to increase the effectiveness of chemical radiosensitizers
Phrase: the effect of postirradiation hypoxia induced by administration of the vasodilator
Inducers of gene: vasodilator

---

Regional cerebral glucose utilization transiently increases during mild hypoxia
Phrase: of the chambers hypoxia was induced by filling the chambers with
Inducers of gene: chambers

---

Peak oxygen intake and hypoxia: influence of physical fitness
Phrase: in the two experiments hypoxia induced an average 28% decrease of
Induced genes: 28%

---

Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine
Phrase: the agent bw12c which also induces substantial tumour hypoxia as a
Inducers of gene: bw12c

---

Formation of S-adenosylhomocysteine in the heart
Phrase: + h2o global hypoxia was induced in the isolated perfused guinea
Induced genes: perfused
Induced genes: guinea

---

Effects of hypoxia on calcium fluxes and force development in the neonatal rat atrium
Phrase: of the high potassium/low sodium induced contracture was increased by hypoxia
Inducers of gene: potassium/low
Inducers of gene: sodium

---

Hyperventilation in the newborn piglet does not increase whole body oxygen consumption as seen in mature animals
Phrase: nor in combination with hypoxia induced any significant change in vo2
Induced genes: vo2

---

Fetal heart rate and transcutaneous monitoring during experimentally induced hypoxia in the fetal dog
Phrase: and transcutaneous monitoring during experimentally induced hypoxia in the fetal dog
Inducers of gene: transcutaneous
Inducers of gene: monitoring

---

The effect of temporary hypoxia on prostaglandin synthesis in mouse brain cell cultures during development
Phrase: temporary hypoxia basal and bradykinin stimulated prostaglandin release were examined most
Induced genes: prostaglandin

---

Role of ATP metabolites in induction of incomplete recovery of cardiac contractile force after hypoxia
Phrase: 45 mins of reoxygenation hypoxia induced a rise in resting tension
Induced genes: tension

---

Uptake of exogenous substrates during hypoxia in fetal lambs
Phrase: after 3 h of hypoxia induced by lowering maternal inspired oxygen
Inducers of gene: lowering
Inducers of gene: inspired

---

Correlated in vivo 31P-NMR and NADH fluorometric studies on gerbil brain in graded hypoxia and hyperoxia
Phrase: normoxia hypoxia of increasing severity induced increasing nad reduction of the
Induced genes: nad

---

Diltiazem and verapamil reduce the loss of adenine nucleotide metabolites from hypoxic hearts
Phrase: perfusate were examined throughout hypoxia induced a marked decline in myocardial
Induced genes: myocardial

---

Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs
Phrase: ventilation acute alveolar hypoxia was induced 10 to 13% inspired o2
Induced genes: 13%
Induced genes: inspired
Induced genes: o2

---

Acute hypoxia decreases cardiac response to catecholamines in exercising humans
Phrase: significant we conclude that hypoxia induced a decrease in cardiac chronotropic
Induced genes: cardiac
Induced genes: chronotropic

---

Hexose monophosphate pathway activity in normal and hypoxic rat brain
Phrase: in the activity of hmp induced by hypoxia is discussed the
Induced genes: hmp

---

Modification by severe hypoxia and diltiazem of dog coronary artery contractions in vitro
Phrase: medium under severe hypoxia and stimulated by pgf2 alpha or k+
Phrase: hypoxia or normoxia diltiazem also inhibited the contractions caused by re-oxygenation
Phrase: re-oxygenation in conclusion severe hypoxia inhibited the contractions induced by ca2+
Phrase: severe hypoxia inhibited the contractions induced by ca2+ in the presence
Inducers of gene: pgf2
Inducers of gene: k+
Repressed genes: contractions
Repressed genes: re-oxygenation
Repressed genes: contractions

---

Adenosine-5
Phrase: decreasing relation was found artificially induced tumour hypoxia resulting from 15
Inducers of gene: artificially

---

In vivo studies on the relationship between intestinal iron
Phrase: two processes hypoxia 3 d stimulated erythropoiesis and resulted in a
Induced genes: erythropoiesis

---

In vivo 31P nuclear magnetic resonance
Phrase: during and after histotoxic hypoxia induced by an injection of potassium
Inducers of gene: potassium

---

Different sensitivity to hypoxia in neuronal activities of lateral vestibular and spinal trigeminal nuclei
Phrase: the lateral vestibular nucleus hypoxia inhibited postsynaptic components of the evoked
Repressed genes: postsynaptic
Repressed genes: evoked

---

Reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs
Phrase: hypoxia vasoconstriction in pig lungs induced by angiotensin infusion was also
Inducers of gene: angiotensin
Inducers of gene: infusion

---

High energy phosphate metabolism in experimental permanent focal cerebral ischemia: an in vivo 31P magnetic resonance spectroscopy study
Phrase: mild hypoxia fio2 14% was induced at the time of the
Phrase: hypoxia fio2 14% only was induced for 20 min hypoxia group
Induced genes: hypoxia
Inducers of gene: fio2
Inducers of gene: 14%

---

A steady-state model of maximal oxygen and carbon dioxide transport in anuran amphibians
Phrase: 3 hypobaric hypoxia 4 artificially induced anemia and 5 beta-blockade of
Induced genes: anemia
Induced genes: beta-blockade

---

The role of the adrenal medulla and peripheral sympathetic nerves in the physiological responses of the fetal sheep to hypoxia
Phrase: blood gas status hypoxia was induced by giving the pregnant ewe
Inducers of gene: pregnant
Inducers of gene: ewe

---

Two long-lasting central respiratory responses following acute hypoxia in glomectomized cats
Phrase: chemo-denervated cats 2 hypoxia was induced by ventilating cats for 10
Inducers of gene: ventilating
Inducers of gene: cats

---

A1 and A2 adenosine receptor regulation of erythropoietin production
Phrase: polycythemic mice exposed to hypoxia inhibited the enhancement in radioiron induced
Repressed genes: radioiron

---

Acute ultrastructural alterations induced by soman and hypoxia in rat hippocampal CA3 pyramidal neurons
Phrase: acute ultrastructural alterations induced by soman and hypoxia in
Induced genes: ultrastructural

---

Myelin lipids of the rat brain in experimental hypoxia
Phrase: obtained indicate that mild hypoxia induces a lesion of myelin membranes
Induced genes: myelin

---

Effects of metabolic inhibition on ion transport by dog bronchial epithelium
Phrase: absorption and short-circuit current were inhibited by approximately 75% by hypoxia
Repressed genes: absorption
Repressed genes: short-circuit

---

[Pre- and postcapillary resistance and transcapillary fluid exchange in the intestine under the effect of hypoxic and hypothermic stimuli in the body]
Phrase: resistance due to hypothermia hypoxia induced no considerable shifts in back-ground
Induced genes: back-ground

---

[Effect of drugs on the resistance of the myocardium to hypoxia]
Phrase: under hypoxic conditions hypoxia was induced by oxygen displacement from the
Inducers of gene: displacement

---

Pharmacokinetics of coenzyme Q10 in recovery of acute sensorineural hearing loss due to hypoxia
Phrase: acute sensorineural hearing loss artificially induced by hypoxia conditions the respiration
Induced genes: sensorineural
Induced genes: hearing
Induced genes: artificially

---

Electrical activity induced by ischemia in the skeletal muscle of patients with spasmophilia
Phrase: spasmophilia of axons to depolarization induced by hypoxia this higher susceptibility
Induced genes: spasmophilia
Induced genes: axons
Induced genes: depolarization

---

Increased ventilatory response to acute hypoxia with high Hb-O2 affinity induced by Na-cyanate treatment in the rat
Phrase: hypoxia with high hb-o2 affinity induced by na-cyanate treatment in the
Phrase: in severe hypoxia was clearly inhibited in the naocn-treated rat beneficial
Inducers of gene: na-cyanate
Repressed genes: naocn-treated

---

Effects of differences of oxygen affinity on circulatory response to hypoxia
Phrase: torr p50 isocapnic hypoxia was induced progressively final pao2 = 45
Induced genes: final
Induced genes: pao2
Induced genes: =

---

Influence of dopamine and norepinephrine on the central ventilatory response to hypoxia in conscious cats
Phrase: co or hypoxic hypoxia was inhibited by apo as the respiratory
Repressors of gene: apo

---

The central effects of thyrotropin-releasing hormone on the breathing movements and electrocortical activity of the fetal sheep
Phrase: remained episodic state related and inhibited by hypoxia as hypothermia presumably
Phrase: by hypoxia as hypothermia presumably induces a surge in trh secretion
Induced genes: surge
Induced genes: trh
Repressed genes: episodic

---

Effects of hypoxia and adrenergic stimulation induced alterations in PGI2 synthesis by diabetic coronary arteries
Phrase: of hypoxia and adrenergic stimulation induced alterations in pgi2 synthesis by
Induced genes: pgi2

---

Possible mechanism by which coenzyme Q10 improves reoxygenation-induced recovery of cardiac contractile force after hypoxia
Phrase: pretreatment with coenzyme q10 hypoxia induced a decline in cardiac contractile
Phrase: during hypoxia and reoxygenation was inhibited completely by the pretreatment changes
Induced genes: cardiac
Induced genes: contractile

---

Analysis of cardiovascular responses evoked following changes in peripheral chemoreceptor activity in the rat
Phrase: chemoreceptors cb; 2 systemic hypoxia induced by n2 breathing for 5
Inducers of gene: n2

---

Animal model of cardiotoxicity: carbon monoxide induced ECG hypoxia masked in light narcosis
Phrase: model of cardiotoxicity: carbon monoxide induced ecg hypoxia masked in light
Inducers of gene: cardiotoxicity:
Inducers of gene: monoxide

---

Moderate hypoxia: reactivity of pial arteries and local effect of theophylline
Phrase: arterial po2 47 torr hypoxia induced a significant mean pial arterial
Induced genes: pial

---

Effects of theophylline on ventilatory response to hypoxic challenge
Phrase: theophylline abolished the periodic breathing induced by hypoxia in one of
Induced genes: theophylline
Induced genes: periodic

---

Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology
Phrase: not directly neurotoxic that peripherally induced hypoxia or anoxia are unlikely
Inducers of gene: neurotoxic
Inducers of gene: peripherally

---

Respiratory and neuroendocrine responses of piglets to hypoxia during postnatal development
Phrase: respiration in older animals was stimulated by hypoxia young piglets had
Induced genes: respiration

---

Maximal Ca2
Phrase: hepes-buffered tyrode solution hypoxia is induced as a means of elevating
Phrase: maximal ca2+-activated pressure hypoxia is induced once again and maximal pressure
Induced genes: again

---

Maturation of the respiratory response to acute hypoxia in the newborn rat
Phrase: of a suprapontine mechanism which inhibits fetal breathing movements during hypoxia
Repressors of gene: suprapontine

---

Haematology and morphological changes in young broiler chicks with experimentally induced hypoxia
Phrase: young broiler chicks with experimentally induced hypoxia maxwell mh
Phrase: broiler chicks subject to experimentally induced hypoxia during incubation were examined
Inducers of gene: broiler
Inducers of gene: chicks
Inducers of gene: broiler
Inducers of gene: chicks

---

Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver
Phrase: 2 h after birth was inhibited by hypoxia 5% o2 glucagon
Phrase: by hypoxia 5% o2 glucagon stimulated the postnatal increase in mitochondrial
Induced genes: postnatal
Induced genes: mitochondrial
Repressed genes: h

---

Differential alteration of dopamine, acetylcholine, and glutamate release during anoxia and
Phrase: with the hypothesis that hypoxia induces a presynaptic deficit that may
Induced genes: presynaptic
Induced genes: deficit

---

Long-chain acylcarnitines mediate the hypoxia-induced increase in alpha 1-adrenergic receptors on adult canine myocytes
Phrase: in alpha 1-adrenergic receptor number induced by 30 minutes of hypoxia
Induced genes: 1-adrenergic

---

Effect of PO2 on prostaglandin E2 production in renal cell cultures
Phrase: studies which suggests that hypoxia stimulates the synthesis of prostanoids in
Phrase: these results indicate that hypoxia stimulates pge2 synthesis in mesangial but
Induced genes: prostanoids
Induced genes: pge2
Induced genes: mesangial

---

Slow axonal transport in experimental hypoxia and in neuropathy induced by p-bromophenylacetylurea
Phrase: experimental hypoxia and in neuropathy induced by p-bromophenylacetylurea nagata
Inducers of gene: p-bromophenylacetylurea

---

Biphasic ventilatory response of adult cats to sustained hypoxia has central origin
Phrase: sciences center denver 80262 hypoxia stimulates ventilation but when it is
Induced genes: ventilation

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Pulse oximetry fails to accurately detect low levels of arterial hemoglobin oxygen saturation in dogs
Phrase: dogs in which hypoxia was induced by stopping the fresh gas
Inducers of gene: stopping
Inducers of gene: gas

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Role of catecholamines in mediating fetal blood volume decrease during acute hypoxia
Phrase: la jolla 92093 hypoxia was induced in chronically catheterized sheep fetuses
Induced genes: catheterized
Induced genes: sheep
Induced genes: fetuses

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Extended wear of contact lenses can compromise corneal epithelial adhesion
Phrase: be a result of contact-lens induced hypoxia
Inducers of gene: contact-lens

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Effect of hypoxia on the contractile response to KCl, prostaglandin F2 alpha, and hemoglobin
Phrase: alpha and hemoglobin hypoxia was induced by changing the bubbling gas
Inducers of gene: bubbling
Inducers of gene: gas

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Cortical control of hypoxic suppression of thermogenesis induced by lateral hypothalamic lesion
Phrase: hypoxic hypoxia blocked the thermogenesis induced by lateral hypothalamic lesion and
Inducers of gene: lateral
Inducers of gene: hypothalamic

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Exercise-induced pulmonary haemorrhage in the horse: results of a detailed clinical, post mortem and imaging study
Phrase: the effects of localised hypoxia induced by maximal exercise and partial
Inducers of gene: exercise

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Effect of pulmonary hypertension on lung compliance in newborn lambs
Phrase: resistance 80% increase that were induced by either hypoxia or acidosis
Induced genes: 80%

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Hypoxia, bradykinin, and prostaglandins stimulate ischemically sensitive visceral afferents
Phrase: the c fibers tested were stimulated by hypoxia the latency of
Phrase: +/- 11 s each afferent stimulated by ischemia and/or hypoxia innervated
Induced genes: c
Induced genes: fibers
Induced genes: s
Induced genes: afferent

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Possible sensory receptor of nonadrenergic inhibitory nervous system
Phrase: capsaicin 5 micrograms/kg or 3 induced hypoxia arterial po2 30-40 torr
Inducers of gene: capsaicin
Inducers of gene: micrograms/kg

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Effects of L-652,731, a platelet-activating factor
Phrase: synthesis pulmonary hypertension and hypoxia induced by 5 micrograms of paf
Inducers of gene: micrograms
Inducers of gene: paf

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Hypoxic ventilatory control in the awake cat five years after carotid body resection
Phrase: hypoxia fio2 less than 012 induced a behavioral 'arousal' in these
Induced genes: behavioral
Induced genes: 'arousal'

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Differential effects of reoxygenation on intracellular calcium and isometric tension
Phrase: a chemical procedure hypoxia was induced by changing the gas mixture
Phrase: course of the isometric twitch induced by hypoxia and reoxygenation cannot
Induced genes: isometric
Induced genes: twitch
Inducers of gene: gas

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Antagonism of the effects of adenosine and hypoxia on atrioventricular conduction time by two novel alkylxanthines: correlation with binding to adenosine A1 receptors
Phrase: in mediating atrioventricular conduction disturbances induced by hypoxia this study was
Induced genes: atrioventricular
Induced genes: conduction
Induced genes: disturbances

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Pathogenesis of Haemophilus influenzae meningitis
Phrase: of medicine seattle the hypoxia induced by decreased cerebrocortical blood flow
Inducers of gene: cerebrocortical

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Erythropoietin production by the fetal liver in an adult environment
Phrase: of host kidneys and was stimulated by anemic hypoxia these results
Induced genes: kidneys

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Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension
Phrase: calves with severe pulmonary hypertension induced by alveolar hypoxia in order
Induced genes: calves
Induced genes: hypertension

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[Effect of piracetam on the resistance of mice to hypoxic hypoxia 2 to 3 months following x-ray irradiation]
Phrase: nonirradiated mice sdh activity was stimulated by hypoxia in a greater
Induced genes: sdh

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Hypoxia inhibits abdominal expiratory nerve activity
Phrase: jul;631:211-20 hypoxia inhibits abdominal expiratory nerve activity
Repressed genes: abdominal
Repressed genes: expiratory

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Arrhythmic activity in reoxygenated guinea pig papillary muscles and ventricular cells
Phrase: minutes of substrate-free hypoxia reoxygenation induced automaticity in a high proportion
Induced genes: automaticity

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[Changes in systemic hemodynamics during exposure of the cooled body to hypoxia]
Phrase: hypoxia 10% o2 in nitrogen induced depressor shifts of the arterial
Induced genes: depressor

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Hypoxia provokes leukotriene-dependent neutrophil sequestration in perfused rabbit hearts
Phrase: isolated buffer-perfused rabbit hearts hypoxia induces ltb4 release from resident myocardial
Induced genes: ltb4
Induced genes: myocardial

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Efficacy of two leukotriene antagonists in rat traumatic shock
Phrase: prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states cgp
Induced genes: bronchoconstriction
Induced genes: cgp

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Enhanced erythropoietin production by calcium entry blockers in rats exposed to hypoxia
Phrase: production were investigated hypoxia was induced in male sprague-dawley rats by
Induced genes: sprague-dawley

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Potassium loss from hypoxic myocardium: influence of external K concentration
Phrase: implicated in the k loss induced by hypoxia or ischemia furthermore
Induced genes: k

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Light absorbance changes in the mouse carotid body during hypoxia and cyanide poisoning
Phrase: 550 nm therefore absorbance changes induced by hypoxia and cyanide were
Induced genes: absorbance

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Synaptosomal uptake and release of dopamine in rat striatum after hypoxia
Phrase: l gross j hypoxia induces alterations of central monoaminergic transmission
Induced genes: monoaminergic
Induced genes: transmission

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[Relation between glutamate and adenine nucleotide levels of heart mitochondria during hypoxia]
Phrase: results suggest that mitochondrial dysfunction induced by hypoxia may also be
Induced genes: mitochondrial

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Changes in inspiratory muscle electrical activity and upper airway resistance during periodic breathing induced by hypoxia during sleep
Phrase: airway resistance during periodic breathing induced by hypoxia during sleep
Induced genes: airway
Induced genes: periodic

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How hyperventilation alters the electroencephalogram: a review of controversial viewpoints emphasizing neurophysiological mechanisms
Phrase: hypoxia secondary to cerebral vasoconstriction induced by hypocapnia during voluntary hyperventilation
Inducers of gene: hypocapnia
Inducers of gene: voluntary
Inducers of gene: hyperventilation

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Effect of substance P on cardiovascular and respiratory function in subjects
Phrase: ventilation at rest and when stimulated by transient hypoxia increased mean
Induced genes: ventilation

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Alteration of chemoreflex phrenic responses by oligomycin in the rabbit
Phrase: that the chemoreflex phrenic responses induced by nacn amc and hypoxia
Induced genes: chemoreflex
Induced genes: phrenic

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Fetal breathing, sleep state, and cardiovascular responses to graded hypoxia in sheep
Phrase: activity and 2 hypoxia probably inhibits eye and breathing movements by
Repressed genes: eye
Repressed genes: movements

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[Effects of maternal glucose loading on brain energy metabolism of fetal rats during hypoxia and recovery]
Phrase: investigated during the state of induced fetal hypoxia and its recovery
Phrase: hysterotomy after 20 minutes of induced hypoxia the concentrations of glucose
Inducers of gene: hysterotomy

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Restimulation of cell cycle progression by hypoxic tumour cells with deoxynucleosides requires ppm oxygen tension
Phrase: cells following 12 h hypoxia induced up to 25% of the
Induced genes: 25%

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Effects of hypoxemia on phrenic nerve responses to static lung inflation in anesthetized dogs
Phrase: level of paw phr was inhibited by hypoxia after cbx but
Repressed genes: paw
Repressed genes: phr

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The differential effects of leukotriene C4 and D4 on the pulmonary and systemic circulations in newborn lambs
Phrase: d4 may mediate pulmonary hypertension induced by hypoxia lt have also
Induced genes: d4
Induced genes: hypertension

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Intracellular pH in sheep Purkinje fibres and ferret papillary muscles during hypoxia and recovery
Phrase: oxygenated solution after hypoxia was inhibited in both preparations in ferret
Repressed genes: ferret

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Changes of synaptosomal energy metabolism induced by hypoxia during aging
Phrase: changes of synaptosomal energy metabolism induced by hypoxia during aging
Induced genes: synaptosomal
Induced genes: energy

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Role of adrenergic-dependent H
Phrase: from red cells in acidosis induced by hypoxia in trout
Induced genes: red
Induced genes: acidosis

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Is phosphodiesterase inhibition arrhythmogenic
Phrase: did not exacerbate the apd-shortening induced by hypoxia since such hypoxia-induced
Induced genes: exacerbate
Induced genes: apd-shortening

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The mode of action of ifenprodil tartrate in isolated canine cerebral and femoral arteries
Phrase: pgf2 alpha 10-5 m but induced relaxation during hypoxia n2 aeration
Phrase: cerebral arteries under normoxia but inhibited it under hypoxia the results
Inducers of gene: pgf2
Inducers of gene: 10-5
Inducers of gene: m
Repressors of gene: normoxia

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Significance of release of adenosine triphosphate and adenosine induced by hypoxia or adrenaline in perfused rat heart
Phrase: of adenosine triphosphate and adenosine induced by hypoxia or adrenaline in
Phrase: understood the onset of hypoxia induced a rapid and transient increase
Induced genes: adenosine
Induced genes: adenosine

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Effects of indomethacin or verapamil on dialysis induced leucopenia and hypoxia in the unstressed sheep
Phrase: indomethacin or verapamil on dialysis induced leucopenia and hypoxia in the
Inducers of gene: indomethacin
Inducers of gene: verapamil
Inducers of gene: dialysis

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Erythropoietin titers in response to anemia or hypoxia
Phrase: hypoxia if the polycythemia was induced by hypertransfusion erythropoietin production in
Phrase: if however the polycythemia was induced by previous exposure to hypoxia
Inducers of gene: hypertransfusion
Inducers of gene: erythropoietin

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Modification by decreased temperature and hypoxia of 45Ca movements in stimulated smooth muscle of rabbit aorta
Phrase: hypoxia of 45ca movements in stimulated smooth muscle of rabbit aorta
Phrase: 60 mm added k+ was inhibited by hypoxia induced by 100%
Phrase: k+ was inhibited by hypoxia induced by 100% n2 or decreased
Phrase: hypoxia increased k+-induced 45ca efflux inhibited k+-induced 45ca uptake and inhibited
Induced genes: aorta
Inducers of gene: 100%
Inducers of gene: n2
Repressed genes: k+
Repressed genes: k+-induced
Repressed genes: 45ca
Repressed genes: uptake

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Dependence of erythropoietin production on blood oxygen affinity and hemoglobin concentration in rats
Phrase: increased exponentially when hypoxia was induced by exposure to simulated altitude
Inducers of gene: altitude

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Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic
Phrase: lesions associated with histotoxic hypoxia induced by subcutaneous injection of 3-nitropropionic
Inducers of gene: subcutaneous
Inducers of gene: 3-nitropropionic

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The antihypertensive drug DL-propranolol inhibits the vascular changes in rat carotid body during long-term hypoxia
Phrase: by light microscopical morphometry hypoxia induced enlargement of the carotid body
Induced genes: enlargement

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Relationship between coronary flow and adenosine release during severe and mild hypoxia in the isolated perfused rat heart with special reference to time-course change
Phrase: endogenous adenosine to coronary vasodilation induced by global myocardial hypoxia was
Induced genes: adenosine
Induced genes: coronary
Induced genes: vasodilation

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DL-propranolol inhibits the vascular changes in the rat carotid body induced by long-term hypoxia
Phrase: in the rat carotid body induced by long-term hypoxia
Phrase: liquid chromatography exposure to hypoxia induced enlargement of the carotid body
Induced genes: enlargement

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[Effects of the addition of carbon dioxide on manifestations of acute hypoxia in rats]
Phrase: belgique in pentobarbitalized rats hypoxia induced by inhalation of o2 8%-n2
Inducers of gene: o2
Inducers of gene: 8%-n2

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Red cell function of carp
Phrase: the onset of hypoxia largely inhibited the increase in red cell
Repressed genes: red

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Calcium antagonists stimulate prostaglandin synthesis by cultured rat cardiac myocytes and prevent the effects of hypoxia
Phrase: hypoxia the three calcium antagonists stimulated pgs synthesis by three- to
Phrase: the decrease in myocyte glycogen induced by hypoxia and stimulate pgs
Induced genes: pgs
Induced genes: three-
Induced genes: glycogen

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Cardiorespiratory responses to shivering in vagotomized pigeons during normoxia and hypoxia
Phrase: from the shivering muscles hypoxia inhibits shivering in both intact and
Repressed genes: shivering

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Effects of hypoxia on cardiac vagal efferent activity and on the action of the vagus nerve at the heart in the dog
Phrase: nerve during progressive asphyxic hypoxia induced by tracheal occlusion cardiac vagal
Inducers of gene: tracheal
Inducers of gene: cardiac
Inducers of gene: vagal

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Role of vasopressin in the cardiovascular response to hypoxia in the conscious rat
Phrase: experiments have demonstrated that hypoxia stimulates the release of arginine vasopressin
Induced genes: arginine
Induced genes: vasopressin

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Initiation and propagation of lipid peroxidation in cerebral infarction models
Phrase: ischaemia load brain hypoxia was induced by means of arterial hypoxaemia
Inducers of gene: hypoxaemia

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[Systemic hemodynamic shifts in the arterial and venous portions of the vascular bed in hypoxia]
Phrase: moderate hypoxia the hypoxic stimulus induces a deficiency of increment in
Induced genes: increment

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Relationship between erythropoiesis and the enhanced intestinal uptake of ferric iron in hypoxia in the mouse
Phrase: in which erythropoiesis had been stimulated by hypoxia fe3+ uptake by
Induced genes: erythropoiesis

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Intrasubject variability of theophylline clearance in a morbidly obese patient
Phrase: changes included hypoxia and medically induced starvation daily theophylline doses ranged
Induced genes: theophylline

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N-methyl-D-aspartate and hypoxia induced Ca2
Phrase: n-methyl-d-aspartate and hypoxia induced ca2+-changes in the ca1 region
Induced genes: ca2+-changes
Induced genes: ca1

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Hypoxia-induced release of atrial natriuretic factor
Phrase: these results demonstrate that hypoxia induces a massive release of anf
Induced genes: anf

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Synergistic interactions between piracetam and dihydroergocristine in some animal models of cerebral hypoxia and ischaemia
Phrase: insults of hypoxia and ischaemia induced by mgcl2 or decapitation in
Inducers of gene: mgcl2
Inducers of gene: decapitation

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Effect of controlled ventilation on renal and splanchnic blood flows during severe arterial hypoxia
Phrase: severe arterial hypoxia hypoxia was induced by inspiration of a 3-5%
Inducers of gene: inspiration
Inducers of gene: 3-5%
Inducers of gene: inspiration
Inducers of gene: 3-5%

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The effect of glutamate on hypoxic newborn rabbit heart
Phrase: hypoxia increased tissue succinate and inhibited tca cycle additional glutamate produced
Repressed genes: tca
Repressed genes: glutamate

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Changes of somatosensory evoked potential accompanying ischaemia and hypoxia in cats
Phrase: was also observed during hypoxia induced by inhalation of nitrogen gas
Inducers of gene: nitrogen
Inducers of gene: gas

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Mechanism of early contractile failure during hypoxia in intact ferret heart: evidence for modulation of maximal Ca2
Phrase: o2-bubbled perfusate and during hypoxia induced by bubbling with room air
Inducers of gene: bubbling
Inducers of gene: room
Inducers of gene: air

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In vivo release of substance P in the nucleus tractus solitarii increases during hypoxia
Phrase: sp-li were measured during hypoxia induced in artificially ventilated cats in
Induced genes: artificially
Induced genes: ventilated
Induced genes: cats

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[Effect of papain and levamisole on the body
Phrase: and monooxygenase system however it induced an increase in tissue hypoxia
Inducers of gene: monooxygenase

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The central effects of morphine on fetal breathing movements in the fetal sheep
Phrase: effects the hyperventilation was also inhibited by hypoxia naloxone alone had
Repressed genes: hyperventilation

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Protective effects of ibuprofen and methylprednisolone on chemotactic factor-induced transcutaneous hypoxia
Phrase: to reverse the transcutaneous hypoxia induced by iv infusion of 1
Inducers of gene: infusion

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Effects of regional alveolar hypoxia and hypercapnia on small pulmonary vessels in cats
Phrase: regional alveolar hypoxia and hypercapnia induced a local vasoconstriction particularly in
Induced genes: vasoconstriction

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Hypoxic incubation leads to concerted changes of carbonic anhydrase activity and 2
Phrase: third week of incubation hypoxia induces a rise of 23 dpg
Induced genes: dpg

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Hypoxia mediated binding of misonidazole in non-malignant tissue
Phrase: a reliable model of homogeneous induced hypoxia in vivo will be
Inducers of gene: reliable

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Carotid body hypercapnia does not elicit ventilatory acclimatization in goats
Phrase: cb hypercapnia the acute hyperventilation induced by cb hypoxia was followed
Induced genes: cb
Induced genes: hypercapnia
Induced genes: hyperventilation

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[Electric activity of hippocampal neurons during asphyxia]
Phrase: for 3-9 min the hypoxia induced phasic changes of the neuronal
Induced genes: phasic

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Hypoxia-induced renal and extrarenal erythropoietin production in posthypoxic or hypertransfused polycythemic rats
Phrase: suggest that exposure to hypoxia induces sensitization of the renal but
Induced genes: sensitization

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Influence of alveolar hypoxia on pulmonary vasomotor responses to almitrine in the dog
Phrase: between the almitrine and hypoxia induced vasoconstriction with multiple linear regression
Induced genes: vasoconstriction
Induced genes: linear

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Effect of hypoxia on prostacyclin production in cultured pulmonary artery endothelium
Phrase: these results suggest that hypoxia inhibits cyclooxygenase at the 10% o2
Repressed genes: cyclooxygenase
Repressed genes: 10%
Repressed genes: o2

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Hyperoxia produces neuronal necrosis in the rat
Phrase: topography and cytopathology from that induced by hypoxia in the same
Induced genes: topography

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Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia
Phrase: inhibitors on atrioventricular conduction disturbances induced by hypoxia anno
Induced genes: atrioventricular
Induced genes: conduction
Induced genes: disturbances

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The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia
Phrase: of da and 5-ht was inhibited by hypoxia whereas the depletion
Repressed genes: 5-ht

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Serotonin uptake by bovine pulmonary artery endothelial cells in culture
Phrase: cells in culture to hypoxia stimulates the membrane activity of 5-ht
Induced genes: 5-ht

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Relationships between cardiac hyperactivity, oxygen tension, and release of vasodilator material in coronary autoregulation of guinea-pig hearts
Phrase: to be myocardial hypoxia which induces the release of vasodilator mediators
Induced genes: vasodilator

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Survival time in hypoxic mice: differentiation between apomorphine-induced hypothermia and antihypoxic properties
Phrase: anoxic hypoxia were studied apomorphine induced hypothermia and an increase in
Induced genes: hypothermia

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On the mechanisms by which hypoxia eliminates digitalis-induced tachyarrhythmias
Phrase: which hypoxia abolishes the tachyarrhythmias induced by cardiac steroids was studied
Inducers of gene: cardiac
Inducers of gene: steroids

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Effects of chronic in utero hypoxia on the pulmonary vasculature of the newborn guinea pig
Phrase: pig of chronic fetal hypoxemia induced by maternal hypobaric hypoxia 380-420
Induced genes: pig
Induced genes: hypoxemia

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Effect of deep hypoxia on acid-base balance in trout: role of ion transfer processes
Phrase: also continuously monitored deep hypoxia induced a short respiratory alkalosis followed
Induced genes: alkalosis

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Somatostatin inhibits the ventilatory response to hypoxia in humans
Phrase: mar;603:997-1002 somatostatin inhibits the ventilatory response to hypoxia
Repressors of gene: mar;603:997-1002
Repressors of gene: somatostatin

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Actions of opiate agonists, naloxone, and paraben preservatives in the rat lung circulation
Phrase: not affect the pulmonary vasoconstrictions induced by hypoxia angiotensin ii or
Induced genes: vasoconstrictions

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Monoamine neurotransmitter metabolism and locomotor activity during chemical hypoxia
Phrase: cd-1 mice chemical hypoxia was induced with nano2 hypoxia did not
Induced genes: nano2
Induced genes: hypoxia
Inducers of gene: cd-1

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Time course of pulmonary vasoconstriction with repeated hypoxia and glucose depletion
Phrase: hypoxia this contraction was not inhibited by nifedipine ca++ -free egta
Repressors of gene: nifedipine
Repressors of gene: ca++
Repressors of gene: -free
Repressors of gene: egta

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The dependence of electrophysiological derangements on accumulation of endogenous long-chain acyl carnitine in hypoxic neonatal rat myocytes
Phrase: carnitine contributes to electrophysiological abnormalities induced by hypoxia we characterized effects
Phrase: accumulation of long-chain acyl carnitine induced by hypoxia tissue was processed
Phrase: the depression of electrophysiological function induced by hypoxia these results strongly
Phrase: a mediator of electrophysiological alterations induced by hypoxia
Induced genes: carnitine
Induced genes: electrophysiological
Induced genes: long-chain
Induced genes: acyl
Induced genes: carnitine
Induced genes: depression
Induced genes: electrophysiological
Induced genes: electrophysiological

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Heart rate and respiratory patterns in mild hypoxia in unanaesthetized newborn mammals
Phrase: no sustained periodic breathing was induced by hypoxia thus mild hypoxia
Induced genes: periodic
Induced genes: periodic

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Effects of hypoxia on rat brain metabolism: unilateral in vivo carotid infusion
Phrase: results demonstrated that limited hypoxia stimulated cerebral glycolysis and produced a
Induced genes: glycolysis

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Effects of procaine on hypoxia induced abnormalities in canine myocardial tissues
Phrase: effects of procaine on hypoxia induced abnormalities in canine myocardial tissues
Induced genes: myocardial

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Ventilation in intact and glossopharyngeal nerve sectioned anaesthetized rats exposed to oxygen at high pressure
Phrase: in ohp they may be stimulated by a histotoxic hypoxia induced
Phrase: stimulated by a histotoxic hypoxia induced by early o2 poisoning since
Phrase: central chemoreceptors by lactic acidosis induced by an ohp-induced histotoxic hypoxia
Induced genes: ohp
Induced genes: chemoreceptors
Induced genes: lactic
Induced genes: acidosis
Inducers of gene: o2
Inducers of gene: poisoning

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Effects of pH alterations and hypoxia on isolated human intestine
Phrase: kcl 10 mm-induced contraction was inhibited by hypoxia but not by
Repressed genes: kcl
Repressed genes: mm-induced
Repressed genes: contraction

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Changes induced by severe hypoxia in respiratory defence reflexes in anaesthetized cats
Phrase: 1986;492:114-21 changes induced by severe hypoxia in respiratory
Induced genes: 1986;492:114-21

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Influence of ganglioglomerular nerve on carotid chemoreceptor activity in the cat
Phrase: certain ggn fibers were strongly stimulated by hypoxia and hypercapnia clearly
Induced genes: ggn
Induced genes: fibers

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Ultrastructure of bone marrow of rats after severe hemodilution with starch or modified hemoglobin
Phrase: in response to tissue hypoxia induced by the exchange-transfusion procedure
Inducers of gene: exchange-transfusion

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Correlation of plasma hypoxanthine and catecholamine levels in the umbilical vein
Phrase: dopamine synthesis tyrosine hydroxylase is inhibited in hypoxia
Repressors of gene: dopamine
Repressors of gene: hydroxylase

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A new animal model for action myoclonus
Phrase: of myoclonic activity neither did induced hypoxia augment the effect of
Inducers of gene: myoclonic

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Effect of acute hypoxia on cardiac function in alloxan-diabetic dogs
Phrase: haemodynamic parameters during acute hypoxia induced by carbon monoxide intoxication and/or
Inducers of gene: monoxide
Inducers of gene: intoxication

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Studies on the calcium antagonistic action of tetrandrine: XIII
Phrase: on myocardial hypoxia and necrosis induced by isoproterenol in rats
Inducers of gene: isoproterenol

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Induction of a heat shock puff by hypoxia in polyt