Post-genomic Research and Technology

Wang, D., Probing the antigenic diversity of carbohydrate molecules. Invited Speaker for The 224th ACS National Meeting, August 18-22, 2002, Boston, MA, USA.

Wang, D, Shaoyi L., Trummer, B. J., and Wang, A. Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells (2002), Nature Biotechnology 21, 275-281

Abstract   |   Full Text   |   PDF   |   Supplementary Information

Deng, C., Zhang, P., Wang, A., Trummer, B. J., Wang, D. Normalization of cDNA microarray data by using neural networks. IEEE World Congress on Computational Intelligence (IJCNN'2002), May 12-17, (2002), Hawaii, USA. (Selected for an oral presentation and a full text publication in the Proceedings).

Wang, D. Carbohydrate microarrays and their application potential. (2001). Invited Lecture in Workshop on Protein Microarray Technologies, April 10, 2001, San Francisco, CA, USA.

Deng, C., Wang, A., Wang, D. and Zhang, P. A nonlinear global optimization approach for normalizing cDNA microarray data (2001), DIMACS Workshop on Analysis of Gene Expression Data, October 24-26, 2001 (Selected for an oral presentation and a full text publication in the Proceedings).

Wang, D., Trummer, B. J., Liu, S., Wang, A., Wang, R. and Zhou, H. (2001). A carbohydrate-based microarray system for characterizing AIDS-associated microbial infections. Abstract and poster for the AIDS Vaccine 2001 Conference, September 5- 8, 2001, Philadelphia, PA, USA.

Wang, D., Kalachikov, S., Liu, S., Wang, A., Zhou, H., Green, P. and Gilliam, T. G. (2000). A functional genomics approach to the molecular mechanism of celiac disease. Abstract and poster for the 9th International Symposium on Celiac Disease, Aug. 10-13, 2000. Baltimore, Maryland, USA.

Wang, D., Wang. A., Liu, S., Zhou, H., and Chenette, E. (2000). MFIS: A high throughput technology for studying the ligand-receptor interaction. Abstract for the 18th International Congress of Biochemistry and Molecular Biology: Beyond the Genome. Birmingham, UK, July 16-20, 2000.


Immunology and Molecular Biology

Wang, D. T-independent IgA responses to microbial polysaccharides. (2001) In: Molecular Immunology of Complex Carbohydrates 2, (ed. A.M. Wu), Kluwer Academic/Plenum Publisher, New York Boston Dordrecht London Moscow.

Schacher, S., Wu. F., Sun, Z.-Y. and Wang, D. (2000). Neuromodulators affect expression of mRNAs encoding different isoforms of Aplysia cell adhesion molecule in sensory and motor neurons. J. Neurobiol., 45:152-161.

Schacher, S., Wu, F., Panyko, J. D., Sun, Z-Y and Wang, D. Expression and branch-specific accumulation of mRNA are regulated by synapse formation and interaction with specific postsynaptic targets. (1999), J. Neurosci., 19, 6338-47.

Wang, D. and Kabat E.A. Antibodies, Specificity, In: Encyclopedia of Immunology, Second Edition, (ed. Delves and Roitt), pp. 148-154, Academic Press, London, 1998.

Seidl K. J., MacKenzie, J. D., Wang, D., Kantor, A. B., Kabat, E. A. and Herzenberg, L. A. Repeated expression of identical heavy and light chain immunoglobulin rearrangements by single antiphosphatidylcholine B cells (1997), Annal. N.Y. Acad. Sci. 815, 484-488.

Seidl K. J., MacKenzie, J. D., Wang, D., Kantor, A. B., Kabat, E. A. and Herzenberg, L. A. Identical heavy and light chain immunoglobulin rearrangements in B cells do not establish clonal origin. (1997). Int. Immunol., 9, 689-702.

Wang, D. and Kabat E. A. Carbohydrate Antigens (Polysaccharides), Chapter 9, In: Structure of Antigens, Volume Three, (ed. M.H.V.Van Regenmortal), pp.247-276, CRC Press, Boca Raton New York London Tokyo, 1996.

Wang, D., Wells, S. M., Stall, A. M. and Kabat, E. A. Reaction of germinal centers in the T-cell-independent response to the bacterial polysaccharide a(1-->6)dextran. (1994) Proc. Natl. Acad. Sci. U.S.A. 91:2502-2506.

Wang, D., Hubbard, J. M. and Kabat, E. A. Modeling Study of the Antibody Combining Sites to a(1-->6) dextrans: Predictions of the Conformational Contribution of VL-CDR3 and Jk Segments to Groove-type Combining Sites (1993) J. Biol. Chem., 168, 20584-20589.

Wang, D., Liao, J., Mitra, D., Akolkar, P. N., Gruezo, F. and Kabat, E. A. The repertoire of antibodies to a single antigenic determinant. (1991) Mol. Immunol. 28, 1387-1397.

Wang, D., Chen, H., Liao, J., Akolkar, P. N., Sikder, S. K., Gruezo, F. and Kabat, E. A. Two families of mAbs to a(1-->6)dextran, VH19.1.2 and VH9.14.7, Show distinct patterns of Jk and JH minigene usage and amino acid substitutions in CDRs. (1990) J. Immunol. 145,3002-3010.

Wang, D. From a single antigen to a carbohydrate microarray: Dr. Kabat's recurring influence (2001). Invited Speaker in the Elvin A. Kabat Memorial Symposium, Columbia University, College of Physicians & Surgeons, November 9th, 2001.

Chenette, E., Wang, A. and Wang, D. An immunological approach to functional analysis of the c-MYC proto-oncogene. Abstract and poster for the 1999 Annual Meeting of American Society for Biochemistry and Molecular Biology, San Francisco, Calif., May 16-20, 1999, and was selected for a Travel Fund Award.

Wang, D., Wang, A., Chenette, E., Jezyk, M. and Jerry L. (1999). IgA responses to microbial polysaccharides in TCR b-/d mice. Abstract and poster for the International Symposium on Molecular Immunology of Complex Carbohydrates-II, and Taiwan-Canada Glycobiology Workshop, Aug.28-Sept.2, 1999, Taipei, Taiwan.

Wang, D. and Erlanger, B. F. Intracellular expression of single chain antibodies to the capsid protein of HIV-1 and their anti-HIV activity. Abstract and poster for the 1997 meeting on Retroviruses, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, May 20-25, 1997.

Wang, D. and Erlanger, B. F. An alternative vaccination strategy against HIV: In vivo induction of antigen-specific IgA in the absence of T cells. (1997), Abstract and poster for the "Symposium on HIV-1 Infection, Mucosal Immunity and Pathogenesis", Sept. 11-13, 1997, at the Natcher Conference Center, National Institutes of Health, Bethesda, Maryland, and was selected for a Travel Fund Award.

Wang, D. Molecular engineering of antibody combining-site, its theory and application. Invited Lecture in the National Academy of Medical Science, Beijing; Shanghai Institute of Biochemistry, National Academy of Science, Shanghai, and at Anhui Medical University, Hefei, P.R.China, October 10-19, 1996.

Wang, D., Kabat, E. A. and Stall, A. M. B cell responses to a(1-->6)dextran in T Cell deficient mice. (1995) Abstract for the 9th International Congress of Immunology, 23-29 July 1995, San Francisco, California, USA, and selected for an oral presentation.