SELECTED PUBLICATIONS

     Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA (2008) A temporal switch from Notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell, 2: 50-59.

     Rando TA (2008) Getting personal with gene therapy for muscular dystrophy. Lancet Neurology, 7: 196-198.

     Gopinath S, Rando TA (2008) Aging of the skeletal muscle stem cell niche. Aging Cell, 7: 590–598.

     Boutet SC, Disatnik M-H, Chan LS, Iori K, Rando TA (2007) Regulation of Pax3 by proteasomal degradation of mono-ubiquitinated protein in skeletal muscle progenitors. Cell, 130: 349-362.

     Rando TA (2007) The immortal strand hypothesis: Segregation and reconstruction. Cell, 129: 1239-1243.

     Conboy MJ, Karasov AO, Rando TA (2007) High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biology, 5: 1120-1126.

     Brack AS, Rando TA (2007) Intrinsic changes and extrinsic influences of myogenic stem cell function during aging. Stem Cell Rev, 3: 226-237.

     Brack AS, Conboy MJ, Lee M, Roy S, Kuo CJ, Keller C, Rando TA (2007) Increased Wnt signaling during aging alters myogenic stem cell fate and increases fibrosis. Science, 317: 807-810.

     Brunet A, Rando TA (2007) Stem to stern. Nature, 449: 288-291.

     Rando TA (2007) Non-viral gene therapy for muscular dystrophies: Progress and challenges. Biochem Biophys Acta, 1772: 263-271.

     Portlock JL, Keravala A, Bertoni C, Lee S, Jarrahian S, Rando TA, Calos MP (2006) Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage phiC31 integrase after non-viral DNA delivery. Hum Gene Ther, 17: 871-876.

     Rando TA (2006) Prognostic value of telomere length: The long and short of it. Ann Neurol, 60: 155-157

     Smythe GM, Rando TA (2006) Altered caveolin-3 expression disrupts PI(3) kinase signaling leading to death of cultured muscle cells. Exp Cell Res, 12: 2816-2825.

     Rando TA (2006) Stem cells, ageing and the quest for immortality. Nature, 441: 1080-1086.

     Quach NL, Rando TA (2006) Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells. Dev Biol, 293: 38-52.

     Bertoni C, Jarrahian S, Wheeler TM, Li Y, Olivares EC, Calos MP, Rando TA (2006) Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration. Proc Natl Acad Sci, USA, 103: 419-424.

     Dhawan J, Rando TA (2005) Stem cells in postnatal myogenesis: Molecular mechanisms of satellite cell quiescence, activation, and replenishment. Trends Cell Biol, 15: 666-673.

     Luo D, Renault VM, Rando TA (2005) The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin Cell Devel Biol, 16: 612-622.

     Rando TA (2005) The adult muscle stem cell comes of age. Nat Med, 11: 829-831.

     Conboy IM, Conboy MJ, Wagers AJ, Girma E, Weissman IL, Rando TA (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature, 433: 760-764.

     Bertoni C, Morris GE, Rando TA (2005) Strand bias in oligonucleotide-mediated dystrophin gene editing. Hum Mol Genet, 14: 221-233.

     Sherwood RI, Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ (2004) Isolation of adult mouse myogenic progenitors: Functional heterogeneity of cells within and engrafting skeletal muscle. Cell, 119: 543-54.

     Rando TA (2004) Artificial sweeteners: Enhancing glycosylation to treat muscular dystrophies. New Eng J Med, 351: 1254-1256.

     Conboy IM, Conboy MJ, Smythe GM, Rando TA (2003) Notch-mediated restoration of regenerative potential to aged muscle. Science, 302: 1575-1577.

     Smythe GM, Eby JC, Disatnik M-H, Rando TA (2003) A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes. J Cell Science, 116: 4739-4749.

     Bertoni C, Lau C, Rando TA (2003) Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping. Hum Mol Genet, 12: 1087-1099.

     Luo D, Rando TA (2003) The regulation of catalase gene expression in mouse muscle cells is dependent on the CCAAT-binding factor NF-Y. Biochem Biophys Res Commun, 303: 609-618.

     Conboy I, Rando TA (2002) The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Devel Cell, 3: 397-409.