SELECTED PUBLICATIONS

     Charville GW, Rando TA (2011) Stem cell aging and non-random chromosome segregation. Proc Roy Soc London, 366: 85-93.

     Boutet SC, Biressi S, Iori K, Natu V, Rando TA (2010) Taf1 regulates Pax3 protein by monoubiquitination in skeletal muscle progenitors. Molecular Cell, 40: 749-761.

     Biressi S, Rando TA (2010) Heterogeneity of muscle stem and progenitors in developmental and postnatal myogenesis. Semin Cell Devel Biol, 21: 845-54.

     Rando TA (2010) Epigenetics and aging. Exp Gerontol, 45: 253-254.

     Brack AS, Seiler-Murphy F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA (2009) BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. Dev Biol, 335: 93-105.

     Nishijo K, Hosoyama T, Bjornson CRR, Schaffer B, Parjapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C (2009) Biomarker system for studying muscle, stem cells and cancer in vivo. FASEB J, 23: 2681-2690.

     Quach NL, Biressi S, Reichardt LF, Keller C, Rando TA (2009) Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion. Mol Biol Cell, 20: 3422-3435.

     Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA (2008) A temporal switch from Notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell, 2: 50-59.

     Rando TA (2008) Getting personal with gene therapy for muscular dystrophy. Lancet Neurology, 7: 196-198.

     Gopinath S, Rando TA (2008) Aging of the skeletal muscle stem cell niche. Aging Cell, 7: 590–598.

     Boutet SC, Disatnik M-H, Chan LS, Iori K, Rando TA (2007) Regulation of Pax3 by proteasomal degradation of mono-ubiquitinated protein in skeletal muscle progenitors. Cell, 130: 349-362.

     Rando TA (2007) The immortal strand hypothesis: Segregation and reconstruction. Cell, 129: 1239-1243.

     Conboy MJ, Karasov AO, Rando TA (2007) High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biology, 5: 1120-1126.

     Brack AS, Rando TA (2007) Intrinsic changes and extrinsic influences of myogenic stem cell function during aging. Stem Cell Rev, 3: 226-237.

     Brack AS, Conboy MJ, Lee M, Roy S, Kuo CJ, Keller C, Rando TA (2007) Increased Wnt signaling during aging alters myogenic stem cell fate and increases fibrosis. Science, 317: 807-810.

     Brunet A, Rando TA (2007) Stem to stern. Nature, 449: 288-291.

     Rando TA (2007) Non-viral gene therapy for muscular dystrophies: Progress and challenges. Biochem Biophys Acta, 1772: 263-271.

     Portlock JL, Keravala A, Bertoni C, Lee S, Jarrahian S, Rando TA, Calos MP (2006) Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage phiC31 integrase after non-viral DNA delivery. Hum Gene Ther, 17: 871-876.

     Rando TA (2006) Prognostic value of telomere length: The long and short of it. Ann Neurol, 60: 155-157

     Smythe GM, Rando TA (2006) Altered caveolin-3 expression disrupts PI(3) kinase signaling leading to death of cultured muscle cells. Exp Cell Res, 12: 2816-2825.

     Rando TA (2006) Stem cells, ageing and the quest for immortality. Nature, 441: 1080-1086.

     Quach NL, Rando TA (2006) Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells. Dev Biol, 293: 38-52.

     Bertoni C, Jarrahian S, Wheeler TM, Li Y, Olivares EC, Calos MP, Rando TA (2006) Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration. Proc Natl Acad Sci, USA, 103: 419-424.

     Dhawan J, Rando TA (2005) Stem cells in postnatal myogenesis: Molecular mechanisms of satellite cell quiescence, activation, and replenishment. Trends Cell Biol, 15: 666-673.

     Luo D, Renault VM, Rando TA (2005) The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin Cell Devel Biol, 16: 612-622.

     Rando TA (2005) The adult muscle stem cell comes of age. Nat Med, 11: 829-831.

     Conboy IM, Conboy MJ, Wagers AJ, Girma E, Weissman IL, Rando TA (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature, 433: 760-764.

     Bertoni C, Morris GE, Rando TA (2005) Strand bias in oligonucleotide-mediated dystrophin gene editing. Hum Mol Genet, 14: 221-233.

     Sherwood RI, Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ (2004) Isolation of adult mouse myogenic progenitors: Functional heterogeneity of cells within and engrafting skeletal muscle. Cell, 119: 543-54.

     Rando TA (2004) Artificial sweeteners: Enhancing glycosylation to treat muscular dystrophies. New Eng J Med, 351: 1254-1256.

     Conboy IM, Conboy MJ, Smythe GM, Rando TA (2003) Notch-mediated restoration of regenerative potential to aged muscle. Science, 302: 1575-1577.

     Smythe GM, Eby JC, Disatnik M-H, Rando TA (2003) A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes. J Cell Science, 116: 4739-4749.

     Bertoni C, Lau C, Rando TA (2003) Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping. Hum Mol Genet, 12: 1087-1099.

     Luo D, Rando TA (2003) The regulation of catalase gene expression in mouse muscle cells is dependent on the CCAAT-binding factor NF-Y. Biochem Biophys Res Commun, 303: 609-618.

     Conboy I, Rando TA (2002) The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Devel Cell, 3: 397-409.