The main areas of interest of the laboratory are muscle stem cell biology (myogenic lineage progression, cell fate determination, asymmetric cell divisions, Notch signaling, Wnt signaling), muscle stem cell aging (epigenetic determinants, local and systemic influences, roles in age-related decline in regeneration and age-related atrophy), muscular dystrophies (disease pathogenesis, gene therapy), and basic muscle cell biology (integrin signaling, myogenic differentiation, muscle progenitor migration). The Rando laboratory is a part of the Department of Neurology and Neurological Sciences at Stanford University School of Medicine and the VA Palo Alto Health Care System. The laboratory is located at the VA Medical Center and is associated with the Stanford Center on Longevity (SCL). Funding for the research comes from the NIH (NIA, NIAMS, and NINDS), the Department of Veterans Affairs, the Muscular Dystrophy Association, the American Federation for Aging Research, the Ellison Medical Foundation, the Duchenne Parent Project (Netherlands) , the Glenn Foundation for Medical Research , the Jain Foundation , the California Institute of Regenerative Medicine , and the Association Française contre les Myopathies (AFM)



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