AmirAli photo

AmirAli H. Talasaz

Research Associate

Stanford Genome Technology Center
Stanford University

Research Experiences

Research Associate and Post-doctoral Fellow

  • Stanford Genome Technology Center and Department of General Surgery(Sept 2007– Present)
      • Electrical detection of HPV viruses and pregnancy protein biomarker with bioactivated nanopores in clinical samples
      • Purification and characterization of circulating tumor cells (CTCs) from blood samples of breast cancer patients
      • Developing nanopore charge sensors in collaboration with Bosch-RTC for PCR-free targeted DNA detection

Research Assistant

  • Stanford Genome Technology Center and Electrical Engineering (Dec 2002 – Sept 2007)
    • Experimental
      • Fabrication of a customized synthetic nanopore device for single molecule analysis
      • Electrical detection of single antibody-antigen interaction with bioactivated nanopores
      • Electrical quantification of target proteins with array of nanopores bioactivated with antibodies
      • Electrical detection of target nucleic-acid biomarkers using nanopores bioactivated with DNA probes
    • Modeling
      • Prediction of protein orientation upon immobilization on biological and non-biological surfaces
      • Electrical impedance modeling of the bioactivated electrodes for integrated sensory systems
      • Electrical modeling of the bioactivated nanopore devices

Collaborator

  • Prof. Jeffrey, General Surgery Department, Stanford University (Dec 2005 – Present)
    • Technology development for circulating tumor cell (CTC) separation from blood
  • Prof. Howe, Electrical Engineering Department, Stanford University (June 2007 – Present)
    • Integrated nanopore charge sensors for PCR-free DNA detection
  • Prof. Dutton, Electrical Engineering Department, Stanford University (Dec 2005 – Present)
    • Predictive electrical modeling of protein orientation upon immobilization on surfaces, electrical properties of bioactivated surfaces and nanopores
  • Prof. Santiago, Mechanical Engineering, Stanford University (Aug 2006 – Present)
    • Real-time control of the zeta potential of the synthetic nanopore devices

Mentorship Experiences

  • Stanford Genome Technology Center
    • Leader and supervisor of the technology section of Stanford Genome Technology Center (consisting of 15 Ph.D. students and post-doctoral fellows) for NIH grant renewal (Jan 2008 – Present)
    • Supervisor of biomedical engineer working on HCG detection and quantification with array of bioactivated nanopores (July 2006 – present)
    • Supervisor of an undergraduate student working on DNA Methylation detection with biological nanopores (May 2006 - Sept 2006)
    • Supervisor of an M.Sc. student working on electrical modeling of the protein immobilization (Jan 2005 - June 2005)

Teaching Experience

  • Mechanical Engineering, Stanford University
    • Fluid Flow in Micro Devices (2007)
  • Electrical Engineering, Sharif University of Technology
    • Communication Systems (2000)
    • Probability and Statistics (2000)

Industrial Experiences

  • Sonitus Medical Inc., Menlo Park, CA (Oct 2006 – Nov 2007)
    • Consultant: Designing integrated bone conduction hearing aid devices
  • National Semiconductor, Sunnyvale, CA (June 2003 - Dec 2003)
    • Summer intern and Circuit Design Contractor: Designed and tested the LNA block for UWB systems.
  • Snowbush Inc., Toronto, Canada (Sep 2002 - Nov 2002)
    • Circuit Design Engineer: Worked as physical and circuit design engineer for a power-line data communication chip.
  • TDK Semiconductor Corp., Mountain View, CA (June 2002 - Sep 2002)
    • Summer Intern: Designed the receiver equalizer for 10Gbps serial link applications.
  • IDS Corp., Tehran, Iran (July 97 - Dec 97)
    • Hardware Engineer: Worked with some test boards for industrial applications
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