Publications:

See end of this section for patents & submitted manuscripts

Michael R Benoit, Dirk Mayer, Yoram Barak, Ian Y Chen, Wei Hu,  Zhen Cheng, Shan X Wang, Daniel M Spielman, Sanjiv S Gambhir, A Matin. 2009. Visualizing implanted tumors in mice with MRI using magnetotactic bacteria. In press, Clinical Cancer Research: Manuscript [PDF] Suppl mat. [PDF]

Steve H. Thorne, Yoram Barak, Wenchuan Liang, Michael H. Bachmann, Jianghong Rao, Christopher H. Contag and A. Matin. 2009. CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy.- Molecular Cancer Therapeutics 8(2): 333-341, Ms [PDF]; Suppl. figures [PDF]; Suppl. tables [PDF]; Video [PDF]

A Matin. Stress, Bacterial: General and Specific. Encyclopedia of Microbiology.  (Moselio Schaechter, Editor), pp. 485-500 Oxford: Elsevier. http://www.elsevier.com/locate/permissionusematerial Publisher does not permit posting of the article.

Barak, Y., Y. Nov., D. Ackerley, and A. Matin. 2008. Enzyme improvement in the absence of structural knowledge - a novel approach. ISME Journal, 2: 171-179 [PDF]

S.V. Lynch, L. Dixon, M.R. Benoit, E.L. Brodie, M. Keyhan, P. Hu, D.F. Ackerley, G.L. Andersen and A. Matin. 2007. Role of the rapA Gene in Controlling Antibiotic Resistance of Escherichia coli Biofilms. Antimicrobial Agents and Chemotherapy, 51 (10): 3650-3658 [PDF]

Matin, A., and S. Lynch, and M. R. Benoit. 2006. Increased bacterial resistance and virulence in simulated microgravity and its molecular basis. Gravitation and Space Biology 19(2): 31-42 [PDF]

Lynch, S.V., K. Mukundakrishnan, M. R. Benoit, P. Ayyaswami, and A. Matin. 2006. Escherichia coli biofilms formed under low shear simulated microgravity in a ground-based system. Applied & Environmental Microbiology 72 (12): 7701-7710 [PDF]

Barak, Y., D. F. Ackerley, C. J. Dodge, B. Lal, A. Cheng, A. J. Francis, and A. Matin. 2006. Analysis of novel soluble Cr(VI) and U(VI) reductases and generation of improved enzymes using directed evolution. Applied and Environmental Microbiology  72 (11): 7074-7082 [PDF]

Ackerley, D.F., Y. Barak, S.V. Lynch, J. Curtin, and A. Matin. 2006. Effect of chromate stress on Escherichia coli K12. Journal of Bacteriology 188 (9): 3371-3381. [PDF]

Barak, Y , Stephen H. Thorne, David F. Ackerley, Susan V. Lynch, Christopher H. Contag, and A. Matin. 2006. New enzyme for reductive cancer chemotherapy (YieF) and its improvement by directed evolution. Molecular Cancer Therapeutics 5(1): 97-103. [PDF]

Matin A., and S. V. Lynch. 2005. Investigating the Threat of Bacteria Grown in Space. ASM News 71(5): 235-240 [PDF]

Lynch S. V. and A. Matin. 2005. Travails of microgravity:man and microbes in space. Biologist 52(2): 80-87 [PDF]

Gonzalez C.F., D.F. Ackerley, S.V. Lynch, and A. Matin. 2005. ChrR, A soluble quinone reductase of Pseudomonas Putida that defends against H2O2. The Journal of Biological Chemistry. 280(24): 22590-22595. [PDF]

Ackerley, D.F., C.F. Gonzalez, C.H. Park, R. Blake II, M. Keyhan, and A. Matin. 2004. Mechanism of chromate reduction by the Escherichia coli protein, NfsA, and the role of different chromate reductases in minimizing oxidative stress during chromate reduction. Environmental Microbiology 6 (8): 851-860 [PDF]

Ackerley, D.F., C.F. Gonzalez, C.H. Park, R. Blake II, M. Keyhan, and A. Matin. 2004. Chromate reducing properties of soluble flavoproteins from Pseudomonas putida and Escherichia coli. Applied & Environmental Microbiology 70: 873-882 [PDF]

Keyhan, M. , D. F. Ackerley, and A. Matin. 2004. Targets of improvement in bacterial chromate bioremediation. In: M. Pellei and A. Porta (Eds.), Remediation of Contaminated Sediments -- 2003. Proceedings of the Second International Conference on Remediation of Contaminated Sediments (Venice, Italy; 30 Sep-3 Oct 2003). ISBN 1-57477-143-4, published by Battelle Press, Columbus, OH. [PDF]

Lynch, S., E.L. Bradie, and A. Matin. 2004. Role and regulation of sigmaS in low shear simulated microgravity-conferred general resistance in Escherichia coli. Journal of Bacteriology 186 (24): 8207-8212 [PDF]

Stone, G., P. Wood, L. Dixon, M. Keyhan and A. Matin. 2002. Tetracycline rapidly reaches all the constituent cells of uropathogenic Escherichia coli biofilms. Antimicrobial Agents and Chemotherapy 46: 2458-2461. [PDF]

Park, C-H., M. Keyhan, B. Wielinga, S. Fendorf, and A. Matin. 2000. Purification to homogeneity and charcterization of a novel Pseudomonas putida chromate reductase. Applied & Environmental Microbiology 66 (5): 1788-1795. [PDF]

Xiong, A., A. Gottman, C. Park, M. Baetens, S. Pandza, and A. Matin. 2000. The EmrR protein represses the Escherichia coli emrRAB multidrug resistance operon by directly binding to its promoter region. In press, Antimicrobial Agents and Chemotherapy. [PDF]

Pandza. S., M. Baetens, C-H. Park, T. Au, M. Keyhan, and A. Matin. 2000. The putative G-protein FLHF has a role in polar flagellar placement and general stress response induction in Pseudomonas putida. Molecular Microbiology 36: 414-423 [PDF]

Matin, A., M. Baetens, S. Pandza, C.H. Park, and S. Waggoner. 1999. Survival strategies in the stationary phase. In Microbial Ecology of Infectious Disease (E. Rosenberg, editor), American Society for Microbiology: Washington D.C., pp. 30-48

Saier, M. H., I.T. Paulsen, and A. Matin. 1997. A Bacterial Model System for Understanding Multidrug Resistance. Microbial Drug Resistance, 3:289-295. [PDF]

Matin, A., C.D. Little, C.D. Fraley, and M. Keyhan. 1995. Use of starvation promoters to limit growth and selectively express trichloroethylene and phenol transformation activity in recombinant Escherichia coli. Applied and Environmental Microbiology, 61:3323-3328. [PDF]

Patents

Matin, A., Y. Barak, S. Lynch, and D. Ackerley, S. Thorne, C. Contag, and J. Rao.. Improved enzymes for reductive prodrug cancer chemotherapy and a novel prodrug that can be visualized in vivo. S06-096

Matin, A., Barak, Y., and Ackerley, D. 2006. Improved nitroreductaseenzymes for bioremediation. Document Type and Number: United States Patent 20070254355

Benoit, M.R., Mayer, D., Barak, Y., Chen, I., Hu, W., Keren, S., Wang, S., Spielman, D., Gambhir, S.S., Matin, A. Magnetatactic bacteria MRI positive contrast enhancement agents and method of use. Docket #221907 - 8530

Manuscripts submitted

Yoram Barak, Frank Schreiber, Steve H Thorne, Christopher H Contag, Dirk deBeer, A Matin. Role of nitric oxide in Salmonella typhimurium-mediated cancer cell killing.

Benoit, MR, Conant, C, Ionescu-Zanetti, C, Schwartz, M, and Matin, A. A Novel Flow-Through Device for Biofilm Viability Screening