Prion Protein(1)

Description
Classic Creutzfeldt-Jakob Disease (CJD), a member of the transmissible spongiform encephalopathies, is a human prion disease that results spontaneously from transformation of normal proteins in the brain into abnormal ones.(2)

Power
 Anyone can get this condition, as it arises spontaneously from misshapen proteins.(3)

Offenses
First signs of CJD include lack of muscular coordination, personality changes, and impaired vision.  As the disease progresses, the symptoms worsen, leading to myoclonus, severe dementia, and loss of vision.  End state CJD includes loss of speech and coma and then death within a year of onset of symptoms.(4)

Defenses

However, certain behavioral interventions such as autoclaving contaminated instruments and waterproofing cuts can reduce risk of transmission.  There also are no cures for CJD.  Instead, care of the patient is focused on making them comfortable and alleviating symptoms.  For instance, opiate drugs can help with the pain the disease causes, while clonazepam or sodium valproate can relieve myoclonus.(5)

Game Action
Because of the onset of dementia, alternate moving forward and backward the value shown on the dice.

One Liner
 Fold the prion protein the wrong way and I’ll develop dementia, eh?