Influenza A - ssRNA genome is 13.6 kb - genome is divided into 8 segments - undergoes genetic drift and shift (every 10-40 years) Clinical features and treatment - incubation period of 1-5 days - infection includes "flu-like" symptoms which appear abruptly, including runny eyes, fever, headache, - antiviral drugs can target either the uncoating process or through neuraminidase inhibition. Influenza B - ssRNA genome is 13.6 kb - genome is divided into 8 segments - undergoes genetic drift Clinical features and treatment - incubation period of 1-5 days - more serious and infects all members of the population. - potentially can result in high morbidity and mortality if genetic shift occurs - antiviral drugs can only target through neuraminidase inhibition
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