Influenza A

- ssRNA genome is 13.6 kb
- genome is divided into 8 segments
- undergoes genetic drift and shift (every 10-40 years)

Clinical features and treatment
- incubation period of 1-5 days
- infection includes "flu-like" symptoms which appear abruptly, including runny eyes, fever, headache,
- antiviral drugs can target either the uncoating process or through neuraminidase inhibition.


Influenza B
- ssRNA genome is 13.6 kb
- genome is divided into 8 segments
- undergoes genetic drift

Clinical features and treatment
- incubation period of 1-5 days
- more serious and infects all members of the population.
- potentially can result in high morbidity and mortality if genetic shift occurs
- antiviral drugs can only target through neuraminidase inhibition


Influenza C
- ssRNA genome is 10 kb
- genome is divided into 7 segments
- has a single envelope protein called HEF which serves as a receptor

Clinical features
- infects children often but only results in minor infection


Tick-borne orthomyxovirus
- ssRNA genome is 10 kb
- genome is divided into 6-7 segments
- tick-borne arbovirus infecting humans and livestock of Europe, Africa, and Asia

Clinical Features
- does not produce disease in humans