St. Louis Encephalitis
Elizabeth Salas &
Humans and Viruses
Human Biology 115A
Date completed: 3/6/00
Description: HTLV-1 is a retorvirus. Virus is enveloped, has incosahedral capsid, and is single stranded RNA.
Power: Integrate genome into host DNA using RNA dependent DNA polymerase.
Molecular Attack: Proviral DNA is integrated into lymphoid cells and its presence increases the cytokines produced. Effects of elevated levels of cytokine induce T cells to proliferate continously which leads to mutations in genes controlling growth. Mutations lead to Adult T cell Lymphoma.
Clinical Manifestations: T cell lymphoma can become malignat and spread to other lymph nodes. Lymphoma also causes skin legion, bone legions, hypercalcemia, and abnormal liver function.
Incubation/Length of Infection: HTLV1 can be a life long infection but not everyone develops symptoms.
Defenses Vaccine: None.
Treatment: Chemotherapy against cancer.
Drugs: Antiretroviral drugs such as AZT.
Behavioral: Educate people about transmission which is by sexual contact, shared needles, blood transfusion, and vertical transmission.
Game Action: Causes cancer in opponent.
HTLV-1 has great oncogenic potential.