St. Louis Encephalitis
Elizabeth Salas &
Humans and Viruses
Human Biology 115A
Date completed: 3/6/00
Description: Member of the arenavirus family. Virus is enveloped with four particle polypeptides and is single stranded RNA.
Power: Transmitted by wild rodents to humans and then causes hemorrhagic fever.
Molecular Attack: Infects lymphocytes, macrophages and neurons that have already differentiated. Enters the cell through smooth wall vesicles and replicates in the cytoplasma.
Clinical Manifestations: Guanarito causes fever, malaise, headache, sore throat, vomiting, convulsions, and hemorrhagic manifestations.
Incubation/Length of Infection: Incubation is on average 6 days and infection can last 5-7 days before death or recuperation. 33% of the cases are fatal.
Defenses Vaccine: None.
Treatment: Passive antibody therapy and controls for fluid, electrolyte and osmatic imbalances.
Drugs: No specific antiviral drug, ribivirin has been suggested.
Behavioral: Rodent control and avoidance of wild rodents by humans.
Game Action: Cause opponent platelet dysfunction and degeneration of the capillary beds which causes leakage of bodily fluids.
Guanarito virus: the culprit behind Venezuelan Hemorrhagic Fever.