Recent Publications

Tan Lab: Publications

Alegado R and Tan MW. Resistance to antimicrobial peptides contributes to persistence of Salmonella typhimurium in the C. elegans intestine. Cell Microbiol. 2008 10(6): 1259-73

Shapira M and Tan MW. Genetic Analysis of Caenorhabditis elegans Innate Immunity. Methods Mol Biol. 2008 415:429-42.

Muir RE and Tan MW. Leucobacter chromiireducens subsp. solipictus subsp. nov., a pigmented bacterium isolated from the nematode Caenorhabditis elegans, and emended description of L. chromiireducens. Int J Syst Evol Microbiol. 2007 57(12):2770-6.

Kurz CL, Shapira M, Chen K, Baillie DL, Tan MW. Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade. Biochem Biophys Res Commun. 2007 Nov 16;363(2):438-43.

Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, Tan MW. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses.Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14086-91.

Beale E, Li G, Tan MW, Rumbaugh KP. Caenorhabditis elegans senses bacterial autoinducers. Appl Environ Microbiol. 2006 Jul;72(7):5135-7.

Thomsen LE, Slutz SS, Tan MW, Ingmer H. Caenorhabditis elegans is a model host for Listeria monocytogenes. Appl Environ Microbiol. 2006 Feb;72(2):1700-1.

Kurz CL, Tan MW. Regulation of aging and innate immunity in C. elegans. Aging Cell. 2004 Aug;3(4):185-93. Review.

Alegado R.A., Campbell M.C., Chen W.C., Slutz S.S., and Tan M.-W. (2003). Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model. Cell Microbiol. 2003 5: 435-44 

Tan M.-W. (2002). Identification of host and pathogen factors involved in virulence using Caenorhabditis elegans. Methods Enzymol. 358: 13-28 

Kim D.H., Feinbaum R., Alloing G., Emerson F.E., Garsin D.A., Inoue H., Tanaka-Hino M., Hisamoto N., Matsumoto K., Tan M.-W., and Ausubel F.M. (2002). A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science. 297: 623-6 

Tan M.-W. (2002). Cross-species infections and their analysis. Annu Rev Microbiol. 56: 539-65

Yorgey, P., Rahme, L.G., Tan, M.-W., and Ausubel, F.M. (2001). The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes, and mice. Mol. Microbiol. 41: 1063-76

Pujol, N., Link, E.M., Liu, L.X., Kurz, C.L., Alloing, G., Tan, M.-W., Ray, K.P., Solari, R., Johnson, C.D., and Ewbank, J.J. (2000). A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans. Curr. Biol. 11: 809-21

Rahme, L.G., Ausubel, F.M., Cao, H., Drenkard, E., Goumnerov, B.C., Lau, G.W., Mahajan-Miklos, S., Plotnikova, J., Tan, M.-W., Tsongalis, J., Walendziewicz, C.L., and Tompkins, R.G. (2000). Plants and animals share functionally common bacterial virulence factors. Proc. Natl. Acad. Sci. 97: 8815-21

Tan, M.-W. and Ausubel. F.M. (2000). Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis. Curr. Opin. Microbiol. 3: 29-34

Shirasu, K., Lahaye, T., Tan, M.-W., Zhou, F., Azevedo, C. and Shulze-Lefert, P. (1999). A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Cell, 99, 355-366

Mahajan-Miklos, S., Tan, M.-W., Rahme, L.G., and Ausubel, F.M. (1999). Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell, 96: 47-56

Tan, M.-W., Rahme, L.G., Sternberg, J.A., Thompkins,R.G. and Ausubel, F.M. (1999). Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc. Natl. Acad. Sci. USA 96: 2408-2413

Tan, M.-W., Mahajan-Miklos, S., and Ausubel, F.M. (1999). Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc. Natl. Acad. Sci. USA 96: 715-720

Rahme, L.G., Tan, M.-W., Le, L., Wong, S.M., Tompkins, R.G., Calderwood, S.B., and Ausubel, F.M. (1997). Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc. Natl. Acad. Sci. 94: 13245-50