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Our interests
are in the area of cellular immunology, and the regulatory interactions
between subpopulations of immune cells. In particular, we are interested
in the identification, function, and molecular mechanisms by which some
subpopulations of lymphocytes amplify the immune response and some suppress
it. Investigation into interactions of the cells during the immune response
to organ and bone marrow transplants and in autoimmune disease is a major
focus of the laboratory research. Developing therapeutic strategies for
organ transplantation and autoimmunity based on these principles is a major
goal. Specific areas of research are as follows. |
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