Simon
Lab Publications
Ma, D., Yang, C-.H.
, McNeill, H., Simon, M.A., and Axelrod, J.D. (2003). Fidelity
in planar cell polarity signaling. Nature 421, 543-7.
PDF
Yang, C. H., Axelrod, J. D., and Simon,
M. A. (2002). Regulation of Frizzled by Fat-like cadherins during
planar polarity signaling in the Drosophila compound eye.
Cell 108, 675-88. PDF
Smith, R. K., Carroll, P. M., Allard,
J. D., and Simon, M. A. (2002). MASK, a large ankyrin repeat
and KH domain-containing protein involved in Drosophila receptor
tyrosine kinase signaling. Development 129, 71-82. PDF
Simon, M. A. (2000). Receptor tyrosine
kinases: specific outcomes from general signals. Cell
103, 13-5. PDF
Herbst, R., Zhang, X., Qin, J., and
Simon, M. A. (1999). Recruitment of the protein tyrosine phosphatase
CSW by DOS is an essential step during signaling by the sevenless
receptor tyrosine kinase. EMBO Journal 18, 6950-61. PDF
Yang, C. H., Simon, M. A., and McNeill,
H. (1999). mirror controls planar polarity and equator formation
through repression of fringe expression and through control of
cell affinities. Development 126, 5857-66. PDF
Guarnieri, D. J., Dodson, G. S., and
Simon, M. A. (1998). SRC64 regulates the localization of a Tec-family
kinase required for Drosophila ring canal growth. Molecular
Cell 1, 831-40. PDF
Dodson, G. S., Guarnieri, D. J., and
Simon, M. A. (1998). Src64 is required for ovarian ring canal
morphogenesis during Drosophila oogenesis. Development
125, 2883-92. PDF
Le, N., and Simon, M. A. (1998). Disabled is a putative adaptor
protein that functions during signaling by the sevenless receptor
tyrosine kinase. Molecular Cell Biology 18, 4844-54. PDF
Allard, J. D., Herbst, R., Carroll, P. M., and Simon, M. A. (1998).
Mutational analysis of the SRC homology 2 domain protein-tyrosine
phosphatase Corkscrew. Journal of Biological Chemistry 273,
13129-35. PDF
McNeill, H., Yang, C. H., Brodsky, M., Ungos, J., and Simon,
M. A. (1997). mirror encodes a novel PBX-class homeoprotein that
functions in the definition of the dorsal-ventral border in the
Drosophila eye. Genes and Development 11, 1073-82. Summary
Herbst, R., Carroll, P. M., Allard, J. D., Schilling, J., Raabe,
T., and Simon, M. A. (1996). Daughter of sevenless is a substrate
of the phosphotyrosine phosphatase Corkscrew and functions during
sevenless signaling. Cell 85, 899-909. PDF
Cooper, J. A., Simon, M. A., and Kussick, S. J. (1996). Signaling
by ectopically expressed Drosophila Src64 requires the protein-tyrosine
phosphatase corkscrew and the adapter downstream of receptor
kinases. Cellular Growth and Differentiation 7, 1435-41.
Summary
Allard, J. D., Chang, H. C., Herbst, R., McNeill, H., and Simon,
M. A. (1996). The SH2-containing tyrosine phosphatase corkscrew
is required during signaling by sevenless, Ras1 and Raf. Development
122, 1137-46. PDF
Simon, M. A. (1994). Signal transduction during the development
of the Drosophila R7 photoreceptor. Developmental Biology
166, 431-42.
Simon, M. A., Dodson, G. S., and Rubin, G. M. (1993). An SH3-SH2-SH3
protein is required for p21Ras1 activation and binds to sevenless
and Sos proteins in vitro. Cell 73, 169-77. Summary
Earlier publications
Fortini, M. E., Simon, M. A., and
Rubin, G. M. (1992). Signalling by the sevenless protein tyrosine
kinase is mimicked by Ras1 activation, Nature 355, 559-61.
Summary
Bowtell, D., Fu, P., Simon, M., and Senior, P. (1992). Identification
of murine homologues of the Drosophila son of sevenless gene:
potential activators of ras, PNAS 89, 6511-5. Summary
Simon, M. A., Bowtell, D. D., Dodson, G. S., Laverty, T. R.,
and Rubin, G. M. (1991). Ras1 and a putative guanine nucleotide
exchange factor perform crucial steps in signaling by the sevenless
protein tyrosine kinase, Cell 67, 701-16. Summary
Simon, M. A., Bowtell, D. D., and Rubin, G. M. (1989). Structure
and activity of the sevenless protein: a protein tyrosine kinase
receptor required for photoreceptor development in Drosophila,
PNAS 86, 8333-7. Summary
Bowtell, D. D., Simon, M. A., and Rubin, G. M. (1989). Ommatidia
in the developing Drosophila eye require and can respond to sevenless
for only a restricted period, Cell 56, 931-6. Summary
Bowtell, D. D., Kimmel, B. E., Simon, M. A., and Rubin, G. M.
(1989). Regulation of the complex pattern of sevenless expression
in the developing Drosophila eye, PNAS 86, 6245-9. Summary
Bowtell, D. D., Simon, M. A., and Rubin, G. M. (1988). Nucleotide
sequence and structure of the sevenless gene of Drosophila melanogaster,
Genes and Development 2, 620-34. Summary
Simon, M. A., Drees, B., Kornberg, T., and Bishop, J. M. (1985).
The nucleotide sequence and the tissue-specific expression of
Drosophila c-src, Cell 42, 831-40. Summary
Kornberg, T., Siden, I., O'Farrell, P., and Simon, M. A. (1985)
The engrailed locus of Drosophila: in situ localization of transcripts
reveals compartment-specific expression, Cell 40, 45-53.
Summary
Simon, M. A., Kornberg, T. B., and
Bishop, J. M. (1983). Three loci related to the src oncogene
and tyrosine-specific protein kinase activity in Drosophila,
Nature 302, 837-9. Summary
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