| Home | People | Jacobs |

Publications (1997 to present)


  • Fischer, K.J., Jacobs, C.R., Levenston, M.E., Carter, D.R., Observations of Convergence and Uniqueness of Node-Based Remodeling Simulations, Annals of Biomedical Engineering, 25:261-268, 1997.

  • Jacobs, C.R., Simo, J.C., Beaupré, G.S., Carter, D.R., Adaptive Bone Remodeling Incorporating Simultaneous Density and Anisotropy Considerations, Journal of Biomechanics, 30:603-613, 1997.

  • Yellowley, C.E., Jacobs, C.R., Li, Z., Zhou, Z., Donahue, H.J., Effects of Fluid Flow on Intracellular Calcium in Bovine Articular Chondrocytes, American Journal of Physiology, 273:C30-C36, 1997.

  • Juliano, P.J., Yu, J.R., Schneider, D.J., Jacobs, C.R., Evaluation of Fracture Predilection in the Calcaneus After External Fixator Pin Removal, Journal of Orthopaedic Trauma, 11:430-434, 1997.

  • Jacobs, C.R. and Eckstein, F., Computer Simulation of Subchondral Bone Adaptation to Mechanical Loading in an Incongruous Joint, The Anatomical Record, 249:317-326, 1997.

  • Fischer, K.J., Jacobs, C.R., Levenston, M.E., Cody, D.D., and Carter, D.R., Bone Load Estimation for the Proximal Femur Using Single Energy Quantitative CT Data, Computer Methods in Biomechanics and Biomedical Engineering, 1(3):233-245, 1998.

  • Fedok, F.G., Van Kooten, D.W., DeJoseph, L.M., Sobota, B., Levin, R.J., Jacobs, C.R., An Analysis of Plating Techniques and Plate Orientation in Repair of Mandibular Angle Fractures: An in Vitro Study, Laryngoscope, 108:1218-1224, 1998.

  • Jacobs C.R., Yellowley C.E., Davis B.R., Zhou Z., Donahue H.J., Differential Effect of Steady versus Oscillating Flow on Bone Cells. Journal of Biomechanics, 31:969-976, ESB Research Award 1998.

  • Eckstein, F., Merz, B., Schön M., Jacobs, C.R., Putz, R., Tension and Bending, but not Compression Alone Determine the Functional Adaptation of Subchondral Bone in Incongruous Joints: Anatomy and Embryology, 199:85-97, 1999.

  • Barr J.D., Hoffman E.J., Davis B.R., Edgar K.A., Jacobs C.R., Microcatheter Adhesion of Cyanoacrylates: Comparison of Normal Butyl Cyanoacrylates to 2-Hexyl Cyanoacrylates. Journal of Vascular and Interventional Radiology, 10:165-168, 1999.

  • Segal L.S., Schneider M.D., Berlin J.M., Bruno A., Davis B.R., Jacobs C.R., The Contribution of the Ossific Nucleus to the Structural Stiffness of the Capital Femoral Epiphysis: A Porcine Models for DDH. Journal of Pediatric Orthopaedics, 19:433-437, 1999.

  • Black K.P., Schneider D.J., Yu J.R., Jacobs C.R., Biomechanics of the Bankart Repair: The Relationship Between Glenohumeral Translation and Labral Fixation Site. American Journal of Sports Medicine, 27:339-344, 1999.

  • Yellowley, C.E., Jacobs, C.R., Donahue H.J., Mechanisms Contributing to Fluid Flow-Induced Ca2+ Mobilization in Articular Chondrocytes: Journal of Cellular Physiology, 180:402-408, 1999.

  • Fernandes P., Rodrigues H., Jacobs C.R., A Model of Bone Adaptation Using a Global Optimisation Criterion Based on the Trajectorial Theory of Wolff. Computer Methods in Biomechanics and Biomedical Engineering, 2:125-138, 1999.

  • Jacobs, C.R., Davis, B.R., Rieger, C.J., Francis, J.J., Saad, M., Fyhrie, D.P., The Impact of Boundary Conditions and Mesh Size on the Accuracy of Cancellous Bone Tissue Modulus Determination Using Large Scale Finite Element Modeling: Journal of Biomechanics, 32:1159-1164, 1999.

  • Fischer K.J., Jacobs C.R., Levenston M.E., Cody D.D., Carter D.R., Proximal Femoral Density Patterns are Consistent with Bicentric Joint Loads: Computer Methods in Biomechanics and Biomedical Engineering, 2: 271-283, 1999.

  • Yellowley, C.E., Jacobs, C.R., Zhou, Z., Li, Z., Donahue, H.J. Functional Gap Junctions Between Osteocytic and Osteoblastic Cells: Journal of Bone and Mineral Research, 15:209-217, 2000.

  • Malecki, E.A., Buhl, K.M., Beard, J.L., Jacobs, C.R., Connor, J.R., Donahue, H.J., Bone Structural and Mechanical Properties are Affected by Hypotransferrinemia but not by Iron Deficiency in Mice: Journal of Bone and Mineral Research, 15:271-277, 2000.

  • Jacobs, C.R., Yellowley, C.E., Nelson, D.R., Donahue, H.J., A Novel Application of Rainflow Cycle Counting to Time-Varying Biophysical Time Data, Computer Methods in Biomechanics and Biomedical Engineering, 3:31-40, 2000.

  • Jacobs, C.R., The Mechanobiology of Cancellous Bone Structural Adaptation, Journal of Rehabilitation Research and Development, 37:209-216, 2000.

  • Lesch, M.L., Schneider, D.J., Deol, G., Davis, B.R., Jacobs, C.R., Pellegrini, V.D., The Consequences of Anterior Femoral Notching in Total Knee Arthroplasty: A Biomechanical Study, Journal of Bone and Joint Surgery, 82-A:1096-1101, 2000.

  • You, J., Yellowley, C.E., Donahue, H.J., Jacobs, C.R., Substrate Deformation Levels Associated With Routine Physical Activity Are Less Stimulatory to Bone Cells Relative to Loading-Induced Oscillatory Fluid Flow, Journal of Biomechanical Engineering, 122:387-393, 2000.

  • Edlich, M.J., Jacobs, C.R., Yellowley, C.E., Donahue, H.J., Oscillating Fluid Flow Regulates Calcium Concentration in Bovine Articular Chondrocytes, Journal of Biomechanics, 34:59-66, 2000.

  • Kurokouchi, K., Jacobs, C.R., Donahue, H.J., Oscillating Fluid Flow Inhibits TNF-a-Induced NF-kB Activation via an IkB Kinase Pathway in Osteoblast-Like UMR106 Cells. Journal of Biological Chemistry, 276: 13499-13504, 2001.

  • You, J., Reilly, G.C., Zhen, X., Yellowley, C.E., Chen Q., Donahue, H.J., Jacobs, C.R., Osteopontin Gene Regulation by Oscillatory Fluid Flow via Intracellular Calcium Mobilization and Activation of Mitogen-Activated Protein Kinase in MC3T3-E1 osteoblasts. Journal of Biological Chemistry, 276:13365-13371, 2001.

Journal Articles

Publications in the Journal of Rehabilitation Research and Development

Jacobs CR. Large-scale finite element solutions on workstations class computers. J Rehab Res Dev, submitted, 2004.

Peer-Reviewed Articles

Godin, L.M., Suzuki, S., Jacobs, C.R., Donahue, H.J., Donahue, S.W., Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction. Biomechanics and Modeling in Mechanobiology, Nov 6, Epub, 2006.

Kim, C., You, L., Yellowley, C.E., Jacobs, C.R., Oscillatory Fluid Flow Induced Shear Stress Decreases Osteoclastogenesis Through Regulation of RANKL and OPG. Bone, 39:1043-1047, 2006.

Malone, A.M., Batra, N.N., Shivaram, G, Kwon, R, You, L., Kim, C., Rodriguez, J, Jair, K. Jacobs, C.R., The Role of the Actin Cytoskeleton in Oscillatory Fluid Flow Induced Signaling in MC3T3-E1 Osteoblasts. American Journal of Physiology-Cell, Jan 24, Epub, 2007.

Rubin, J., Rubin, C., Jacobs, C.R., Mechanical signaling in bone. Gene, 367:1-16, 2006. Shin C, Chaudhari A, Andriacchi T: The influence of deceleration forces on ACL strain during single leg landing: a simulation study. Journal of Biomechanics, (Epub ahead of print, June 22, 2006).

Batra NN, Li YJ, Yellowley CE, You L, Malone A, Kim C, and Jacobs CR: Effects of Short-term Recovery Periods on Fluid Induced Signaling in Osetoblastic Cells. Journal of Orthopaedic Research, 38:1909-1917, 2005.

Offley SC, Guo TZ, Wei T, Clark DJ, Vogel H, Lindsey DP, Jacobs CR, Yao W, Lane, NE, and Kingery WS: Capsaicin-sensitive Sensory Neurons Contribute to the Maintenance of Trabecular Bone Intregrity, Journal of Bone and Mineral Research 20:257-67, 2005.

Malone AM, Narain R, and Jacobs CR: Biomechanical Regulation of Mesenchymal Stem and Progenitor Cells and the Implications for Regenerative Medicine. Current Opinion in Orthopaedics, 16:363-367, 2005.

Alford AI, Yellowley CE, Jacobs CR, Donahue HJ. Increases in cytosolic calcium, but not fluid flow, affect aggrecan mRNA levels in articular chondrocytes. J Cellular Biochem, 90:938-944, 2003.

Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Cycle number and waveform of fluid flow affect bovine articular chondrocytes. Biorheology, 41:315-22, 2004.

Guo TZ, Offley SC, Boyd EA, Jacobs CR, Kingery WS. Substance P Signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I. Pain, 108:95-107, 2004.

Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. The sensitivity of tibiofemoral contact pressure to the size and shape of the lateral and medial menisci. J Orthop Res, 22: 807-814, 2004.

Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically-induced calcium signaling in osteoblastic cells. Bone, 35: 656-663, 2004.

Haut Donahue TL, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Mechanosensitivity of bone cells to oscillating fluid flow-induced shear stress may be modulated by chemotransport. J Biomech, 36: 1363-71, 2003.

Kingery WS, Offley SC, Guo TZ, Davies MF, Clark JD, Jacobs CR. A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section. Bone, 33:927-936, 2003.

Li YJ, Batra NN, You L, Meier SC, Coe IA, Yellowley CE, Jacobs CR. Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. J Orthop Res, 22: 1283-1289, 2004.

Reilly GC, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. Biorheology, 40:591-603, 2003.

Alford AI, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism. Bone, 33: 64-70, 2003.

Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrell PA, Donahue HJ. Parallel changes in extracellular matrix protein gene expression, bone formation, and biomechanical properties in aging rat bone. J Musculoskel Res, 6: 157-169, 2002.

Donahue SW, Donahue HJ, Jacobs CR. Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. J Biomech, 36: 35-43, 2003.

Haut-Donahue TL, Rosenberg G, Jacobs CR, Weiss WJ. Finite element analysis of stresses developed in blood sacs of a pusherplate blood pump. Computer Methods Biomech Biomed Eng, 6: 7-15, 2003.

Haut-Donahue TL, Hull ML, Rashid MM, Jacobs CR. How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. J Biomech, 36: 19-34, 2003.

Saunders MM, Schwentker EP, Kay DB, Bennett GL, Jacobs CR, Verstraete MC, Njus GO. Finite element analysis as a tool for parametric prosthetic foot design and evaluation. Technique development in the solid ankle cushioned heel (SACH) foot. Computer Methods Biomech Biomed Eng, 6: 75-87, 2003.

Saunders MM, You J, Zhou Z, Li Z, Yellowley CE, Kunze EL, Jacobs CR, Donahue HJ. Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium. Bone, 32: 350-356, 2003.

You J, Jacobs CR, Steinberg TH, Donahue HJ. P2Y purinoceptors are responsible for oscillatory fluid flow induced intracellular calcium mobilization in osteoblastic cells. J Biol Chem, 277: 48724-729, 2002.

Donahue SW, Jacobs CR, Donahue HJ. Flow-induced calcium oscillations in rat osteoblastic cells are age, loading frequency, and shear stress dependent. Amer J Physiol, 281: C1635-1641, 2001.

Fernandes PR, Folgado J, Jacobs CR, Pellegrini V. A contact model with ingrowth control for bone remodelling around cementless stems. J Biomech, 35: 167-176, 2002.

Haut TL, Hull ML, Rashid MM, Jacobs CR. A finite element model of the human knee joint for the study of tibio-femoral contact. J Biomech Eng, 124: 273-280, 2002.

Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. J Biomech, 36: 19-34, 2003.

Saunders MM, You J, Trosko JE, Yamasaki H, Li Z, Donahue HJ, Jacobs CR. Gap junctions and fluid flow response MC3T3-E1 cells. Amer J Physiol, 281: C1917-1925, 2001.

Jacobs CR. The mechanobiology of cancellous bone structural adaptation. J Rehab Res Dev, 37: 209-216, 2000.
http://www.vard.org/jour/00/37/2/jacob372.htm

Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrel PA, Donahue HJ. Aged bone displays an increased responsiveness to low-intensity resistance exercise. J Appl Physiol, 90: 1359-1364, 2001.

Kurokouchi K, Jacobs CR, Donahue HJ. Oscillating fluid flow inhibits TNF-a-induced NF-kB activation via an IkB kinase pathway in osteoblast-like UMR106 cells. J Biol Chem, 276: 13499-13504, 2001.

Moulton MJR, Parentis MA, Kelly MJ, Jacobs CR, Naidu SH, Pellegrini VD. Influence of metacarpophalangeal joint position on basal joint-loading in the thumb. J Bone Joint Surg, 83-A: 709-716, 2001.

You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR. Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogenactivated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem, 276: 13365-13371, 2001.

In Review - 2006

Sabsovich, I., Clark, D.J., Liao, G., Peltz, G., Lindsey, D.P, Jacobs, C.R., Yao, W., Guo, T.Z., Kingery, W.S., Bone microstructure and its associated genetic variability in 12 inbred mouse strains: uCT study and in silico genome scan, Submitted, Bone.

Wang, L., Zhao, R., Shi, X., Wei, T., Halloran, B.P., Clark, D.J., Jacobs, C.R., Kingery, W.S., Substance P regulates osteogenic activity of mouse bone marrow stromal cells, Submitted, Bone.

You, L., Temiyasathi, S., Lee, P., Kim, C., Tummala, P., Yao, W., Kingery, W.S., Jacobs, C.R., Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone, Submitted.

Abstracts - 2006

Jacobs C.,You, J., Reilly, G., Batra, N., Li, Y., Malone, A., Themiyasathit, S., Tang, J., Stearns, T., Anderson. C., Cellular Mechanotransduction in Bone: Moving Towards a Molecular Mechanism. European Cells and Materials Journal, 8:S3, p. 8, July 2006.

Kwon, R.Y., Anyeni, O.A., Jacobs, C.R., Mechanics of Deformation of Osteoblastic Cells Exposed to Steady and Oscillatory Fluid Flow. Transactions of the Orthopaedic Research Society, p. 129, March 2006.

Kwon, R.Y., Ayeni, O.A., Jacobs. C.R., Investigating the Mechanics of Fluid Flow Induced Deformation in Bone Cells. Proc Soc Physical Regulation in Medicine and Biology, p. 43, January, 2006.

Litzenberger, J.B., Tummala, P., Powell, C., Jacobs. C.R., Inhibition of Beta-1 Integrin Signaling in Bone Cells Decreases Mechanosensitivity. Transactions of the Orthopaedic Research Society, p. 1023, March 2006.

Malone A.M., Anderson, C.T., Tummala P., Stearns, T., Jacobs. C.R., Are Primary Cilia Mechanosensory Organelles in Bone Cells? Proc Soc Physical Regulation in Medicine and Biology, p. 50, January, 2006.

Malone, A.M., Cheng, Beam, M., Tummala, P., Jacobs, C.R., Fak Mediated ERK ½ Phosphorylation with Exposure to Oscillatory Fluid Flow. Transactions of the Orthopaedic Research Society, p. 1022, March 2006.

You, L., Temiyasathit, C., Jacobs. C., Osteocytes are Mechanosensors in the Inhibition of Bone Resorption due to Mechanical Loading. Proc Soc Physical Regulation in Medicine and Biology, p. 56 January, 2006.

You, L., Temiyasathit, C., Lee, P., Kim, C.H., Tummala, P., Yao, W., Kingery W., Jacobs. C., Osteocytes as Mechanosensors in the Inhibition of Bone Resorption due to Mechanical Loading. Transactions of the Orthopaedic Research Society, p. 382, March 2006.


Conference Presentations and Abstracts - Prior to 2006

Schwenke T, Wimmer M, Schneider E, Sumner D, Rosenberg A, Andriacchi T, Jacobs J. Joint moments affect tibial polyethylene failure in TKA. Am Physical Therapy Assoc Comb Sects Mtg, San Francisco, CA, Mar, 2004.

Wimmer M, Moisio K, Genge R, Rosenberg A, Jacobs J, Andriacchi T, Martell. Hip joint moments predict polyethylene wear in total hip arthroplasty, Orthop Res Soc Conf, San Francisco, CA, Mar, 2004.

Batra N, Li YJ, Jacobs CR. Effect of short term recovery periods on fluid flow induced calcium oscillations in MC3T3-E1 osteoblastic cells. Trans Orthop Res Soc, 28: 129, 2003.

Batra NN, Li YJ, Yellowley CE, You L, Jacobs CR. Short term recovery periods lead to multiple oscillatory fluid flow induced intracellular calcium oscillations in osteoblastic cells. Proc ASME Summer Bioeng Conf, p 705, 2003.

Godin LM, Donahue HJ, Jacobs CR, Donahue SW. Calcium fingerprints in bone cell mechanotransduction. Trans Orthop Res Soc, 28: 679, 2003.

Godin LM, Donahue HJ, Jacobs CR, Donahue SW. Characteristics of intracellular calcium oscillations in osteoblatic cells during repetitive loading conditions. Proc ASME Summer Bioeng Conf, p 1057, 2003.

Haut-Donahue TL, Donahue H, Jacobs CR, Yellowley C. Annexin V contributes to mechanotransduction in osteoblast-like cells. Trans Orthop Res Soc, 27: 577, 2002.

Jair KY, Batra NN, You L, Jacobs CR. Dynamics of F-actin cytoskeleton reorganization under loading-induced oscillatory fluid flow in MC3T3-E1 pre-osteoblasts. Proc ASME Summer Bioeng Conf, p 697, 2003.

Kingery W, Offley S, Guo T-Z, Joseph A, Lindsey D, Jacobs CR. Capsaicin sensitive sensory neurons maintain normal bone integrity. 25th Ann Mtg Amer Soc Bone and Mineral Res, Minneapolis, MN, Sep, 2003.

Li YJ, Batra N, Yellowley CE, Jacobs CR. Effects of fluid induced oscillatory shear stress on human marrow stromal cell differentiation. Trans Orthop Res Soc, 28: 680, 2003.

You L, Li YJ, Batra NN, Jacobs CR. The effect of oscillatory fluid flow on human marrow stomal cell proliferation. Proc ASME Summer Bioeng Conf, p 267, 2003.

You L, Li YJ, Batra NN, Jacobs CR. Design of a 3D Microfluidic system for loading fluid flow on osteocyte processes in vitro. Proc ASME Summer Bioeng Conf, p 695, 2003.

Bergandi JA, Rumi MN, Saunders MM, Jacobs CR, Pellegrini VD. Periprosthetic osteolysis in a rabbit model: a comparison of latency to onset in cemented and cementless knee implants. Trans Orthop Res Soc, 26: 1082, 2001.

Donahue SW, Jacobs CR, Donahue HJ. Mechanosensitivity of rat osteoblastic cells is a function of age, loading frequency, and shear stress. Trans Orthop Res Soc, 26: 564, 2001.

Saunders MM, You J, Trosko J, Yamasaki H, Donahue HJ, Jacobs CR. Oscillatory flow induced prostaglandin E2 production is dependent upon gap junctional intercellular communication in osteoblastic MC3T3-E1 cells. Trans Orthop Res Soc, 26: 565, 2001.

You J, Saunders MM, Yellowley CE, Donahue HJ, Jacobs CR. Oscillatory flow stimulates prostaglandin E2 release via protein kinase A in MC3T3-E1 osteoblasts involving cyclooxygenase-2. Trans Orthop Res Soc, 26: 326, 2001.

You J, Saunders MM, Yellowley CE, Donahue HJ, Jacobs CR. Torsion and bending evaluation of femoral allograft fixation techniques in a cadaveric model: a comparison of double plate to IM nail and plate fixation. Trans Orthop Res Soc, 26: 523, 2001.

Book Chapter

Wimmer MA, Andriacchi TP. The basic science of human motion and its relevance to wear and failure in total knee arthroplasty. In: Joint Replacements and Bone Resorption: Pathology, Biomaterials and Clinical Practice, eds: Shanbhag A, Rubash H, Jacobs J. New York: Marcel Dekker, 2001.

Invited Lectures

Jacobs CR. Mechanisms of cellular mechanosensitivity. Gordon Conf Cartilage Biology and Pathology, Venture, CA, Mar, 2003.

Jacobs CR. Cellular mechanotransduction in bone. University of California, Davis, CA, Apr, 2003.

Jacobs CR. Cellular mechanotransduction in bone. Dept Endocrinology, University of California, San Francisco, CA, May, 2003.

Jacobs CR. Cellular mechanotransduction in bone. Stanford-Guidant Lecture Series, Sep, 2003.

Jacobs CR. Topic in biomechanics: cell mechanics. Sun Valley Hard Tissue Workshop, Sun Valley, ID, Aug 14-18, 2000.

Data Ready for Publication

Batra NN, Shivaram G, Kwon R, You L, Chi-Hyun RJ, Malone A, Jair K, and Jacobs CR: The Role of the Actin Cytoskeleton in Oscillatory Fluid Flow Induced Signaling in MC3T3-E1 Osteoblasts. American Journal of Physiology-Cell, Submitted.

Fernandes PR, Folgado J, Jacobs CR, and Pellegrini VD: Influence of Femoral Stem Geometry, Material, and Extent of Porous Coating on Bone Ingrowth and Atrophy in Cementless Total Hip Arthroplasty: An Iterative Finite Element Model. Journal of Bone and Joint Surgery, Submitted.

Kim C, Yellowley CE, and Jacobs CR: Oscillatory Fluid Flow Induced Shear Stress Decreases Osteoclastogenic Activity through Regulation of RANKL and OPG. Bone, Submitted.

Offley SC, Guo TZ, Wei T, Min E, Lindsey DP, Jacobs CR, and Kingery WS: Unilateral immobilization induces regional reductions in trabecular bone integrity and sensory neuronal signaling, Submitted.

Rubin J, Rubin C, and Jacobs CR: Mechanical signaling in bone. Gene, Accepted.

You L, Temiyasathi S, Lee P, Kim C, Tummala P, Yao W, Kingery WS, and Jacobs CR: Osteocytes as Mechanosensors in the Inhibition of Bone Resorption Due to Mechanical Loading. Proceedings of the National Academy of Science. Submitted.

Jacobs CR, Bechtel JB, Davis BR, Naidu SH, Pellegrini VD. Fatigue lifetime studies of a new bone cement formulation.


Updated 10/10/2007