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Publications

Publications submitted to the Journal of Rehabilitation Research and Development

Worthen LC, Kim CM, Kautz SA, Lew HL, Kiratli BJ, and Beaupré GS: Key Characteristics of Walking Correlate with Bone Density in Individuals with Chronic Stroke. Accepted to: J Rehabil Res Dev, July 2005.

Peer-Reviewed Articles

Beaupré GS, Lew HL: Bone Density Changes following Stoke. American Journal of Physical Medicine and Rehabilitation, 85(5):464-472, 2006.

Draper CE, Besier TF, Gold GE, Fredericson M, Fiene A, Beaupré GS, Delp SL: Is Cartilage Thickness Different in Young Subjects with and without Patellofemoral Pain? Osteoarthritis and Cartilage, 14(9):931-937, 2006.

Gosch C, Verrette R, Lindsey DP, Beaupré GS, Lehnert B: Comparison of initial compression force across the subtalar joint by two different screw fixation techniques. Journal of Foot and Ankle Surgery, 45(3):168-73, 2006.

Li KW, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, Beaupré GS: Gene Regulation Ex Vivo within a Wrap-Around Tendon. Tissue Engineering, 12(9):2611-8, 2006.

Miyanishi K, Trindada MCD, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL: Effects of hydrostatic pressure and transforming growth factor-beta3 on adult human mesenchymal stem cell chondrogenesis in vitro. Tissue Engineering, 12(6):1419-1428, 2006.

Miyanishi K, Trindada MCD, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL: Dose- and time-dependent effects of cyclic hydrostatic pressure on Transforming Growth Factor-beta3-induced chondrogenesis by adult human mesenchymal stem cells in vitro. Tissue Engineering, 12(8):2253-2262, 2006.

Worthen LC, Kim CM, Kautz SA, Lew HL, Kiratli BJ, Beaupré GS: Key Characteristics of Walking Correlate with Bone Density in Individuals with Chronic Stroke. Journal of Rehabilitation Research and Development, 42(6):761-768, 2005.

Besier TF, Draper CE, Gold GE, Beaupré GS, and Delp SL: Patellofemoral joint contact area increases with knee flexion and weight bearing. Journal of Orthopaedic Research, 23: 345-350, 2005.

Besier TF, Gold GE, Beaupré GS, and Delp SL: Subject specific modeling to estimate patellofemoral joint cartilage stress. Med Sci Sports Exercise, 37(11)1924-1930, 2005.

Carpenter RD, Beaupré GS, Lang TF, Orwoll ES, and Carter DR: New QCT Analysis Approach Shows the Importance of Fall Orientation on Femoral Neck Strength. J Bone Min Res, 20(9):1533-1542, 2005.

Carter DR, Beaupré GS, Wong M, Smith RL, Andriacchi TP, Schurman DJ, and Smith RL: The mechanobiology of articular cartilage development and degeneration. Clin Orthop Relat Res. Oct(427 Suppl):S69-77, 2004.

Carter DR, Beaupré GS, Wong M, Smith RL, Andriacchi TP, and Schurman DJ: The mechanobiology of articular cartilage development and degeneration. Clin Orthop Rel Res, 427S:S69-S77, 2004.

Gold GE, Besier TF, Draper CE, Asakawa DS, Delp SL, and Beaupré GS: Weight-bearing MRI of patellofemoral joint cartilage contact area. J Magn Reson Imaging, 20:526-530, 2004.

Li KW, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, and Beaupré GS: Gene Regulation Ex Vivo Within a Wrap-Around Tendon. Submitted to Tissue Engineering on June 7, 2005, currently being revised.

Richards JC, Majumdar S, Lindsey DP, Beaupré GS, and Yerby SA: The treatment mechanism of an interspinous process implant for lumbar neurogenic intermittent claudication. Spine, 30(7):744-749, 2005.

Mandell JA, Carter DR, Goodman SB, Schurman DJ, Beaupré GS. A conical-collared femoral stem can improve stress transfer and limit micromotion compared to conventional designs. Clin Biomech, 19:695-703, 2004.

Hernandez CJ, Beaupré GS, Carter DR. A theoretical analysis of the changes in basic multicellular unit activity at menopause. Bone, 32: 357-363, 2003.

Hernandez CJ, Beaupré GS, Carter DR. A theoretical analysis of the relative influences of peak BMD, age-related bone loss and menopause on the development of osteoporosis. Osteoporos Int, 14: 843-847, 2003.

Loboa EG, Wren TAL, Beaupré GS, Carter DR. Mechanobiology of soft skeletal tissue differentiation - a computational approach of a fiber-reinforced poroelastic model based on homogeneous and isotropic assumptions. Biomech Model Mechanobiol, 2: 83-96, 2003.

Wren TAL, Loboa EG, Beaupré GS, Carter DR. Mechanobiology of skeletal tissue differentiation and regeneration. Recent Research Developments in Biomechanics, Transworld Research Network, Kerela, India, 1-10, 2003.

Wren TAL, Lindsey D, Beaupré GS, Carter DR. Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendons. Ann Biomed Eng, 31: 710-717, 2003.

Hernandez CJ, Beaupré GS, Marcus R, Carter DR. Long term predictions of the therapeutic equivalence of daily and less than daily alendronate dosing. J Bone Min Res, 17: 1662-1666, 2002.

Les CM, Whalen RT, Yan CH, Cleek TM, Beaupré GS, Willis JS. The x-ray attenuation characteristics of human calcaneal marrow do not change significantly during adulthood. J Orthop Res, 20: 633-641, 2002.

van der Meulen MCH, Beaupré GS, Smith RL, Giddings VL, Allen WA, Athanasiou KA, Zhu CF, Mandell JA, Song Y, Poser RD, Goodman SB.Factors influencing changes in articular cartilage followinghemiarthroplasty in sheep. J Orthop Res, 20: 669-675, 2002.

Hernandez CJ, Beaupré GS, Keller TS, Carter DR: The influence of bone volume fraction and ash fraction on bone strength and modulus. Bone, 29:74-78, 2001.

Hernandez CJ, Beaupré GS, Marcus R, Carter DR: A theoretical analysis of the contributions of remodeling space, mineralization and bone balance to changes in bone mineral density during alendronate treatment. Bone, 29:511-516, 2001.

Loboa Polefka EG, Beaupré GS, Carter DR: Mechanobiology of initial pseudarthrosis formation with oblique fractures. J Orthop Res, 19:1067-1072, 2001.

Wren TAL, Yerby SA, Beaupré GS, Carter DR: Influence of bone mineral density, age, and strain rate on the failure mode of human Achilles tendons. Clin Biomech, 16(6):529-534, 2001.

Wren TAL, Yerby SA, Beaupré GS, Carter DR: Mechanical properties of the human Achilles tendon. Clin Biomech, 16(3):245-251, 2001.

Yerby SA, Paal AF, Young PM, Beaupré GS, Ohashi KL, Goodman SB: The effect of a silane coupling agent on the bond strength of bone cement and cobalt-chrome alloy. J Biomed Mater Res 49:127-133, 2000.

Giddings VL, Beaupré GS, Whalen RT, Carter DR: Calcaneal loading during walking and running. Med Sci Sports Exercise 32(3):627-634, 2000.

Yan CH, Whalen RT, Beaupré GS, Yen SY, Napel S: Reconstruction algorithm for poly-chromatic CT imaging: with application to beam hardening correction. IEEE Transactions on Medical Imaging, 19(1):1-12, 2000.

Wren TAL, Beaupré GS, Carter DR: Tendon and ligament adaptation to exercise, immobilization, and remobilization. J Rehab R&D, 37(2):217-224, 2000.

Wren TAL, Beaupré GS, Carter DR: Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia. J Rehab R&D, 37(2):135-143, 2000.

Beaupré GS, Stevens SS, Carter DR: Mechanobiology in the development, maintenance and degeneration of articular cartilage. J Rehab R&D 37:145-151, 2000.
http://www.vard.org/jour/00/37/2/beaup372.htm

Hernandez CJ, Beaupré GS, Carter DR: A model of mechanobiologic and metabolic influences in bone adaptation. J Rehab R&D, 37:235-244, 2000.
http://www.vard.org/jour/00/37/2/herna372.htm

Wren TAL, Yerby SA, Beaupré GS, Carter DR: Interpretation of calcaneus DXA measurements in the assessment of osteopenia and fracture risk. J Bone Min Res 15(8):1573-1578, 2000.

Hernandez CJ, Beaupré GS, Marcus R, Carter DR: Long term predictions of the therapeutic equivalence of daily and less than daily alendronate dosing. Accepted to JBMR.

In Press - 2006

Li KW, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, Beaupré GS: Gene Regulation Ex Vivo Within a Wrap-Around Tendon. In Press: Tissue Engineering,12(9), 2006.

Miyanishi K, Trindada MCD, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL: Effects of hydrostatic pressure and transforming growth factor-beta3 on adult human mesenchymal stem cell chondrogenesis in vitro. Accepted: Tissue Engineering.

In Review - 2006

Draper CE, Santos JM, Kourtis L, Besier TF, Beaupré GS, Gold GE, Delp SL: Accuracy of measuring joint motion using real-time MRI: A phantom study. Journal of Magnetic Resonance Imaging, Submitted, Dec 2006.

Abstracts - 2006

Besier TF, Gold GE, Delp SL, Beaupré GS: Patellofemoral cartilage stress is increased by femoral internal rotation. Trans Orthop Res Soc 31:249, 2006.

Boyer KA, Beaupré GS, Andriacchi TP: Gender differences in hip joint kinetics in healthy older walkers as a consideration in treatment interventions for osteoporosis. Trans Orthop Res Soc, 32:1825, 2007.

Keenan KE, Kourtis L, Besier T, Lindsey DP, Gold GE, Delp SL, Beaupré GS: Web-based resource for the computation of cartilage biphasic material properties with the interpolant response surface method. Trans Orthop Res Soc, 32:603, 2007.

Li KW, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, Beaupré GS: Mechanobiological influences on tissue-engineered tendon implants in vitro. Trans Orthop Res Soc 30:399, 2005.

Li KW, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, Beaupré GS: Gene Regulation Ex Vivo Within a Wrap-Around Tendon. Conditionally accepted to: Tissue Engineering, June, 2005.

Meetings and Presentations - 2006

Draper C, Kourtis L, Santos J, Besier T, Gold G, Beaupré G, Delp S: Feasibility of using realtime MRI to measure joint kinematics. Presented at the 5th World Congress of Biomechanics, Munich, poster # 4642, July 29 – Aug 4, 2006.

Draper CE, Besier TF, Beaupré GS, Delp SL, Gold GE: Males have Thicker Load-bearing Patellofemoral Joint Cartilage than Females. Presented at the 14th Scientific Meeting of the International Society for Magnetic Resonance in Medicine, May 6-12, 2006.

Epstein NJ, Besier TF, Draper CE, Yoon K, Fredericson M, Beaupré GS, Delp SL, Gold GE: MRI analysis of patellar and femoral rotation during upright, weight- bearing knee flexion. Presentation # 002, 106th Annual Meeting of the American Roentgen Ray Society, May 1, 2006.

Gold GE, Besier TF, Draper CE, Santos JM, Fredericson M, Butts Pauly K, Beaupré GS, Delp SL: Patellofemoral Pain: Analysis with Upright Real-Time MRI and 3D Finite Element Modeling. Society of Computed Body Tomography and Magnetic Resonance, April 3-7, 2006. Winner of the SCBT/MR Lauterbur Award for outstanding scientific paper on cross sectional imaging.

Books

Carter DR, Beaupré GS. Skeletal Function and Form - Mechanobiology of Skeletal Development, Aging, and Regeneration. Cambridge University Press, New York, 2001.

Patents

Carter DR, Mandell JA, Beaupre GS, Schurman DJ: Prostheses having curvilinear collars. U.S. Patent 6,383,226. Issue date May 7, 2002.

Beaupré GS, Carter DR, Hayes WC: Increasing bone fracture resistance by repeated application of low magnitude forces resembling trauma forces. U.S. Patent 5,752,925. Issue date May 19, 1998.

Conference Presentations and Abstracts - Prior to 2006

Agarwal A, Lindsey DP, Thomas R, Longaker MT, Smith RL, Carter DR, and Beaupré GS: Mechanosensitivity of MSCs to cyclic pressure or stretch in a collagen I scaffold. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, Vol 29:844, 2004.

Draper C, Fiene A, Besier T, Gold GE, Beaupré GS, and Delp SL: Is Patellar Cartilage Thickness Reduced in Individuals with Patellofemoral Pain? 2005 Joint Meeting of the International Society of Biomechanics and the American Society of Biomechanics. Poster # 184, July 31 – August 5, 2005, Cleveland, OH.

Draper C, Besier T, Santos J, Blemker S, Pauly J, Beaupré GS, Delp SL, and Gold GE: Estimation of Patellar Tendon Strain In Vivo During Static and Dynamic Loaded Knee Flexion. 13th Meeting of the International Society for Magnetic Resonance in Medicine, Miami, May 7-13, 2005.

Gold GE, Besier TF, Draper CE, Asakawa DS, Delp SL, and Beaupré GS: Upright Weight-Bearing MRI of Patellofemoral Joint Cartilage Contact Area. 2004 Meeting of the Radiological Society of North America, p. 467, 2004.

Li KL, Linsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, and Beaupré GS: Mechanobiologic influences on tissue-engineered tendon implants in vitro. Transactions of the 51st Annual Meeting of the Orthopaedic Research Society, Vol 30:399, 2005.

Li KL, Lindsey DP, Wagner DR, Giori NJ, Schurman DJ, Goodman SB, Smith RL, Carter DR, and Beaupré GS: Mechanobiological influences on tissue-engineered tendon implants in vitro. Trans Orthop Res Soc 30:399, 2005.

Miyanishi K, Trindade MCD, Lindsey DP, Goodman SB, Schurman DJ, Beaupré GS, Carter DR, and Smith RL: Intermittent hydrostatic pressure upregulates endogenous transforming growth factor 1 and 3 gene expression in human mesenchymal stem cells. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, Vol 29:636, 2004.

Miyanishi K, Trindade MCD, Lindsey DP, Goodman SB, Schurman DJ, Beaupré GS, Carter DR, and Smith RL: Mechanoregulation of chondrogenic gene exrpression in human mesenchymal stem cells. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, Vol 29:836, 2004.

Santos JM, Gold GE, Besier TF, Hargreaves BA, Draper CE, Beaupré GS, Delp SL, and Pauly JM: Full-Flexion Patellofemoral Joint Kinematics with Real-Time MRI at 0.5T. 13th Meeting of the International Society for Magnetic Resonance in Medicine, Miami, May 7-13, 2005.

Besier TF, Draper CE, Gold GE, Asakawa DE, Beaupré GS, Delp SL. Joint loading and knee flexion increase patellofemoral joint contact area. Trans Orthop Res Soc, 29: 1264, 2004.

Besier TF, Gold GE, Draper C, Powers, C, Delp SL, Beaupré GS. Methods to determine in vivo cartilage stresses in the patellofemoral joint from weight-bearing MRI. Ann Mtg Am Soc Biomech, Sept, 2004.

Carpenter RD, Beaupré GS, Lang TF, Orwoll ES, Carter DR. Femoral neck strength estimates are affected by measurement location and bending direction. Trans Orthop Res Soc, 29:492, 2004.

Gold GE, Besier TF, Draper CE, Asakawa DS, Delp SL, Beaupre GS. Weight-bearing MRI of the patellofemoral joint cartilage. 12th Mtg Intl Soc Magnetic Resonance in Medicine, Kyoto, Japan, May, p 2588, 2004.

Carpenter RD, Lang TF, Beaupré GS, Orwoll ES, Carter DR. Estimating femoral neck section modulus using quantitative computed tomography. Trans Orthop Res Soc, 28: 1249, 2003.

Hernandez CJ, Beaupré GS, Marcus R, Carter DR. The relative influence of peak BMD, age-related bone loss and menopause on the development of osteoporosis. 24th Ann Mtg Am Soc Bone and Mineral Res, San Antonio, TX, Sept 20-24, 2002.

Cleek TM, Beaupré GS, Matsubara M, Whalen RT. Accurate measurement of bone density with QCT. 15th Intl Bone Densitometry Workshop, Monterey, CA, July 21-26, 2002.

Richards J, Majumdar S, Lindsey DP, Beaupré GS, Yerby SA. Quantitative changes in the lumbar spinal canal with an interspinous implant. 9th Intl Mtg Advanced Spine Techniques, Montreux, Switzerland, May 23-25, 2002.

Gold G, Lindsey D, Beaulieu C, Beaupre G: A mechanical cartilage phantom for magnetic resonance imaging. Tenth Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, May 18-24, 2002.

Gold GE, Vasanawala S, Hargreaves B, Nishimura D, Pauly J, Beaupré GS. Improved imaging of osteoarthritis using fluctuating equilibrium magnetic resonance imaging. Proc 3rd VA Natl Rehab Res Dev Conf, pp 5-6, 2002.

Cody DJ, Gold GE, Delp SL, Frederiscon M, Beaupré GS. The use of magnetic resonance imaging and finite element modeling to assess the role of elevated cartilage stresses in patellofemoral pain. Proc 3rd VA Natl Rehab Res Dev Conf, p 103, 2002.

Gold GE, Lindsey DP, Beaulieu C, Beaupré GS. A mechanical cartilage phantom for magnetic resonance imaging. 10th Mtg Intl Soc Magnetic Resonance in Medicine, Honolulu, HI, May 18-24, 2002.

Hernandez CJ, Beaupré GS, Carter DR: Changes in bone mineral density after alendronate treatment may be caused by increased degree of mineralization. Trans Orthop Res Soc 26:475, 2001.

Hernandez CJ, Beaupré GS, Keller TS, Carter DR: Changes in ash fraction influence bone strength more than changes in bone volume fraction. Trans Orthop Res Soc 26:529, 2001.

Yerby SA, Beaupré GS, Young PM, Smith RL, Sims GE: The effect of shock wave therapy at the bone/screw interface. Trans Orthop Res Soc 26:976, 2001.

Bouletreau PJ, Warren SM, Paccione MF, Greenwald JA, Nijher NS, McCarthy JG, Carter DR, Beaupre GS, Loboa E, Longaker MT: New developments in craniofacial distraction. 3^rd International Congress of Craniofacial and Maxillofacial Distraction, Paris, June 14-16, 2001.

Gold GE, Wren TAL, Nayak K, Nishimura DG, Beaupré GS: In Vivo Short Echo Time Imaging of Achilles Tendon. Annual Meeting of the International Society for Magnetic Resonance in Medicine, Glasgow, Scotland, April 21-27, 2001.

Hernandez CJ, Beaupré GS, R. Marcus R, Carter DR: Changes in Activation Frequency are More Influential Than Changes in Focal Bone Balance in Predictive Models of BMD Response to Estrogen Depletion and Replacement. J Bone Min Res 16(Suppl 1):S281, 2001.

Hernandez CJ, Beaupré GS, R. Marcus R, Carter DR: Long Term Predictions of Less than Daily Alendronate Treatment. J Bone Min Res 16(Suppl 1):S408, 2001.

Invited Lectures

Carter DR, van der Meulen MCH, Loboa EG, Beaupré GS. The role of musculoskeletal forces in the development and regulation of bone structure. Intl Conf Osteoperosis and Bone Res, Oct, 2003.

Last updated 10/10/2007