Selected media coverage
Coverage by university news services
humanities and science scholars join forces for groundbreaking
research on Jewish genetics (Stanford Report, March 1, 2013)
launches new center to advance 'information age of genomics'
(Stanford Report, December 3, 2012)
chromosomes agree, Stanford researchers find signatures of human
migrations and marriage practices (Stanford Report,
August 14, 2012)
bolsters migration theory (Brown Daily Herald, October
- U-M study reveals
surprising lack of genetic diversity in the most widely used human
embryonic stem cell lines (University of Michigan News
Service, December 16, 2009)
Native Americans Descended From a Single Ancestral Group, DNA Study
Confirms (UC Davis News and Information, April 28, 2009)
- U-M researchers
release most detailed global study of genetic variation
(University of Michigan News Service, February 20, 2008)
Gene study adds weight to theory that native people of the Americas
arrived in a single main migration across the Bering Strait
(University of Michigan Health System Newsroom, November 27, 2007)
of Genetic Traits Makes Progress (USC News, December
- One small snip from
man; one giant leap for the genome (University of Michigan
News Service, December 7, 2006)
All in the Family (USC News, December 19, 2003)
DNA suggests humans descend from small ancestral population
(Stanford Report, May 28, 2003)
(USC News, December 19, 2002)
More media coverage...
Comments in scientific journals on research from the lab
Wang has been awarded a Howard Hughes Medical Institute
International Student Research Fellowship. The fellowship provides
support to international students in the third to fifth years of their PhD
work. Congrats Chaolong!
7-1-2011 The Rosenberg Lab has moved from the
University of Michigan to Stanford University!
4-25-2011 Graduate student Mike DeGiorgio
successfully defended his PhD dissertation in bioinformatics on
"Genetic variation and modern human origins." Mike's thesis includes
investigations of models of human origins on the basis of simulations
and analytical summary statistics; mathematical work on the estimation
of heterozygosity in cases in which samples contain related
individuals; and development of phylogenetic methods for inferring
species trees in the setting in which gene trees are discordant. Mike
will be joining the lab of Rasmus Nielsen at the University of
California, Berkeley, supported by an NSF Postdoctoral Fellowship in
Biology. Congrats Mike!
Wang has been awarded a Rackham Predoctoral Fellowship from the
Rackham Graduate School. The fellowship provides a year of support to
graduate students nearing the conclusion of their PhD work.
2-11-2011 This month's cover of the American
Journal of Human Genetics is inspired by the work of
DeGiorgio and Ivana Jankovic on estimating heterozygosity
in samples with relatives, published in Genetics last December.
Past lab news
12-28-2011 Two papers from the lab investigate
properties of human haplotype variation. Former
Scheet and his student Anthony San Lucas have
a visualization tool for examining haplotypes in populations (Genet
Epidemiol 36: 17-21). Graduate student
postdoc Mattias Jakobsson,
Pemberton and collaborators have studied patterns of haplotype
variation in African populations, interpreting them in light of models of
human evolution and investigating their implications for imputation-based
association studies of disease (Genet Epidemiol 35: 766-780).
12-20-2011 A paper from the lab has appeared on the
properties of ranked gene trees conditional on species trees (Math
Biosci 235: 45-55). In contrast to previous work from the lab on
gene trees and species trees, this study takes into consideration not only
the gene tree topology, but also the sequences of events involved in
producing gene trees. The project is a collaboration with former postdoc
and Tanja Stadler.
12-17-2011 Postdoc Paul
Verdu's paper on
a mathematical model of admixture has appeared in Genetics. This
work uses a mechanistic evolutionary model to examine the properties of
admixture predicted for an admixed population, as a function of parameters
that describe the way in which admixture takes place over time.
10-13-2011 Three recent papers from the lab provide
new developments in population-genetic theory.
has investigated the properties of private alleles at microsatellite loci
in a two-population model (Theor Pop Biol 80:
Boca has evaluated population divergence measures involving
admixed populations in a model of admixture between two source groups
(Theor Pop Biol 80:
DeGiorgio and James
Degnan have analyzed gene genealogies in a model designed for
considering human migrations out of Africa (Genetics 189:
10-11-2011 Work from the lab on human genetic
variation and genome-wide association studies is featured in the October
2011 cover story of Genome
Huang successfully defended her PhD dissertation in bioinformatics
on "Genotype imputation in worldwide human populations: empirical and
theoretical approaches." Lucy's thesis studies genotype imputation
accuracy in diverse human populations, including African populations, as a
function of different ways of selecting imputation reference panels; it
also considers investigations of sample-size inflation for maintaining
power in imputation studies, and coalescent models for genotype
imputation. Congrats Lucy!
9-22-2011 "A test of the influence of continental axes
of orientation on patterns of human gene flow"
Ramachandran and Noah Rosenberg has appeared online in
the American Journal of Physical Anthropology. This paper
provides a test on the basis of genetics of Jared Diamond's hypothesis
in Guns, Germs, and Steel that differences in contintental
orientation contributed to differences in the speed of technological
diffusion in Eurasia and the Americas.
news story] [Discovery
American news story]
Daily Herald news story]
Wang has been named a winner of a Delill Nasser travel award from
the Genetics Society of America. Chaolong will use the award to attend
the 12th International Congress of Human Genetics, which will be held in
Montreal in October 2011. Congrats Chaolong!
[GSA Reporter news story]
10-7-2010 The work of postdoc Trevor
Pemberton et al. on identifying unexpected close relatives in
the newly reported individuals from Phase 3 of the HapMap project has
been published in the American Journal of Human Genetics.
Trevor's paper will be
informative for researchers working closely with the HapMap 3 samples
who require knowledge of relatedness in their analyses. [Genome Technology news
9-20-2010 Graduate student Mike
DeGiorgio is one of two recipients of this year's Program in
Biomedical Sciences Graduate Student Award for Excellence in Research.
9-17-2010 Graduate student Mike DeGiorgio
and postdoc Erkan
Buzbas will be speaking about their work at the upcoming
meeting of the American Society of Human Genetics in Washington, DC.
Mike will speak about coalescence time distributions in a serial
founder model of human evolutionary history, and his trip is sponsored
by a FASEB Minority Access to Research Careers travel award. Erkan
will speak about balancing selection on human immune system genes,
with travel support from a Delill Nasser travel award from the
Genetics Society of America. Graduate students Lucy Huang,
Ethan Jewett, Zach
Szpiech, and Chaolong
Wang, as well as postdocs
Pemberton and Paul Verdu, will be presenting posters at
7-28-2010 Ivana Jankovic's work on genetic
diversity in the Yellowstone wolves has been reported in Molecular
Ecology. Ivana has found that genetic diversity in the reintroduced
population is relatively stable, supporting field observations that the
wolves are effective at avoiding inbreeding.
6-28-2010 Graduate students Mike
DeGiorgio, Ethan Jewett, and Zach Szpiech
have been awarded fellowships from the University of Michigan Genome
Science Training Program. The fellowships provide 1-2 years of
support for graduate training.
5-19-2010 Postdoc Trevor
Pemberton was awarded a University of Michigan Center for
Genetics in Health and Medicine postdoctoral fellowship. The
fellowship will support Trevor's work on genomic patterns of
homozygosity in worldwide human populations.
5-1-2010 Undergraduate Ivana Jankovic will be
leaving for the University of California, Los Angeles to begin her
MD/PhD. Congrats Ivana!
4-7-2010 Graduate student Lucy Huang has been
awarded a Rackham Predoctoral Fellowship from the Rackham Graduate
School. The fellowship provides a year of support to graduate
students nearing the conclusion of their PhD work.
1-27-2010 Chaolong Wang et
al. have developed an approach for quantitatively comparing the
similarity of statistical maps of population-genetic variation with
geographic maps of sampling variation. The paper is available here.
12-17-2009 In collaboration with Sean Morrison's
group, the lab has conducted a study that finds that the most widely
used human embryonic stem cell lines derive from donors with European
ancestry. The limited population diversity in widely used lines has
important implications for ongoing work on human embryonic stem cells.
news release] [UPI
is available for download. This program
examines alleles private to combinations of populations, correcting
for sample size differences across populations. A description of
ADZE is reported in Bioinformatics 24: 2498-2504
2-26-2008 "Genotype, haplotype, and copy-number
variation in worldwide human populations" has appeared in Nature.
This work was featured in several news stories.
12-3-2007 "Genetic variation and population
structure in Native Americans" is now available online in PLoS
Genetics. This work was featured in Science News.
10-10-2007 CLUMPP version 1.1.1 is now available
for download. A description of CLUMPP is reported in Bioinformatics
23: 1801-1806 (2007).
6-28-2007 distruct version 1.1 is now
available for download. The new version
includes color schemes from ColorBrewer.
A description of distruct appears in Molecular Ecology Notes 4: