▸ Publications

Riedel-Kruse*, I.H., Chung, A.M., Dura, B., Hamilton, A.L., and B.C. Lee 
Design, engineering and utility of biotic games
Lab Chip (2011). 11, 14-22 (pdf) (journal) (viewpoint)

In this paper we propose that modern bioengineering technologies - such as micro-fluidics or synthetic biology - could be used as a new gaming platform - similar to electronics enabling video games. We give proof of concept by presenting various "biotic games". We also discuss future applications, especially for education and large scale science research, as biotic games would enable non-scientists to engage and interact with modern biotechnology. Driving this concept and its application forward is an active focus in our lab.

Riedel-Kruse*, I.H., Müller, C., and A.C.Oates*
Synchrony dynamics during initiation, failure and rescue of the segmentation clock.
Science (2007) 317: 1911. (pdf) (journal) (Editors' choice)

This paper demonstrates how quantitative gene perturbation methods combined with biophysical modeling can lead to deeper conceptual insights into developmental systems. We use zebrafish as a model to study how the Delta-Notch pathway enables genetic oscillators inside the segmentation clock to be synchronized despite the presence of developmental noise. This multi-cellular genetic network is termed the segmentation clock and drives segmentation in vertebrates. In our lab we use a similar biophysics approach to study the dynamical and mechanical aspects of other developmental pattern formation systems.

B. M. Friedrich, I. H. Riedel-Kruse, J. Howard and F. Jülicher* 
High-precision tracking of sperm swimming fine structure provides strong test of resistive force theory
Journal of Experimental Biology (2010) 213, 1226. (pdf) (journal)

Du J., Riedel-Kruse, I.H., Nawroth, J.C., Laurent, G.J., Roukes, M.L., and S.C. Masmanidis*  
Three-dimensional extracellular recording of neuronal activity with multifunctional microelectrode arrays.
J. Neurophysiol. (2009) 101: 1671. (pdf) (journal)

Riedel-Kruse", I.H., Hilfinger", A., Howard*, J., and F. Jülicher*

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How molecular motors shape the flagellar beat.
HFSP Journal (2007) 1: 192. (pdf) (journal)

Riedel*, I.H., Kruse, K., and J. Howard*
A self-organized vortex array of hydrodynamically entrained sperm cells.
Science (2005) 309: 300. (pdf) (journal) (Editors' choice)

Riedel, I., Zahn, P., and I. Mertig*
Ab initio calculation of the transmission coefficients from a superlattice electronic structure.
Phys. Rev. B (2001) 63: 195403. (pdf) (journal)