Using mouse genetics to activate Wnt signaling in specific cell types

No replies
soha338
Offline
Joined: 06/10/2011

Hello,

 

I am interested in rescuing Wnt signaling in a Wnt7a mutant mouse, ideally in particular cell type using Cre driver. Does anyone know of any floxed alleles for any of the downstream effector proteins, such as Dvl1, etc? According to MGI, a floxed Dvl1 is in progress...but does anyone have any other ideas?

 

Thank you for any suggestions!