Human Wnt genes

There is a separate table for syntenic linkage groups. See the comparative table of all vertebrate Wnt genes for and explanation of the numbering/nomenclature. Also, see alignments of Wnt proteins


Linked to HUGO

Disease

WNT1

 Osteogenesis imperfecta  Fahiminiya et al, 2013

Pyott et al, 2013

 

Keupp et al., 2013

 

WNT2
 
WNT2B/13
 
WNT3 Tetra-Amelia (Niemann 2004)
WNT3A  
WNT4 Mullerian-duct regression and virilization (Biason-Lauber 2004)

SERKAL syndrome (Mandel, 2008)

WNT5A  
WNT5B Associated with Susceptibility to type 2 diabetes (Kanazawa 2004)
WNT6    
WNT7A Fuhrmann syndrome
WNT7B
WNT8A
 
WNT8B  
WNT9A

(previously WNT14)

 
WNT9B

Previously WNT15)

   
WNT10A Odonto-onycho-dermal dysplasia Adaimy, 2007 , Bohring, 2009
WNT10B Mutations in Obesity patients Christodoulides 2006

Split-Hand/Foot Malformation (Ugur 2008)

WNT11  
WNT16 Bone density (Zheng et al, 2012)