Publications

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2007
Marino S, Nusse R. "Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal." PLoS One. 2007;2:e519. Abstract
Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO. "Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments." PLoS One. 2007;2:e945. Abstract
2006
Ching W, Nusse R. "A dedicated Wnt secretion factor." Cell. 2006;125:432-433. Abstract
Galli LM, Barnes T, Cheng T, et al. "Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3." Dev Dyn. 2006;235:681-690. Abstract
Wodarz A, Stewart DB, Nelson JW, Nusse R. "Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells." J Cell Sci. 2006;119:2425-2434. Abstract
Mikels AJ, Nusse R. "Wnts as ligands: processing, secretion and reception." Oncogene. 2006;25:7461-7468. Abstract
Gordon MD, Nusse R. "Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors." J Biol Chem. 2006;281:22429-22433.
Mikels AJ, Nusse R. "Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context." PLoS Biol. 2006;4:e115. Abstract
Blitzer JT, Nusse R. "A critical role for endocytosis in Wnt signaling." BMC Cell Biol. 2006;7:28. Abstract
2005
Gordon MD, Dionne MS, Schneider DS, Nusse R. "WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity." Nature. 2005;437:746-749. Abstract
Povelones M, Nusse R. "The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling." EMBO J. 2005;24:3493-3503. Abstract
Nusse R. "Wnt signaling in disease and in development." Cell Res. 2005;15:28-32. Abstract
Nusse R. "Cell biology: relays at the membrane." Nature. 2005;438:747-749.
Povelones M, Howes R, Fish M, Nusse R. "Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism." Genetics. 2005;171:1643-1654. Abstract
Kon C, Cadigan KM, da Silva SL, Nusse R. "Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila." Genetics. 2005;169:2087-2100. Abstract
2004
Johnson ML, Harnish K, Nusse R, Van Hul W. "LRP5 and Wnt signaling: a union made for bone." J Bone Miner Res. 2004;19:1749-1757.
Galli LM, Willert K, Nusse R, et al. "A proliferative role for Wnt-3a in chick somites." Dev Biol. 2004;269:489-504. Abstract
Nelson JW, Nusse R. "Convergence of Wnt, beta-catenin, and cadherin pathways." Science. 2004;303:1483-1487. Abstract
Kuhnert F, Davis CR, Wang H-T, et al. "Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1." Proc Natl Acad Sci U S A. 2004;101:266-271. Abstract
Marino S, Romelfanger C, Yokota Y, Nusse R. "Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse." BMC Cancer. 2004;4:91. Abstract
Verras M, Brown J, Li X, Nusse R, Sun Z. "Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells." Cancer Res. 2004;64:8860-8866. Abstract
Groth AC, Fish M, Nusse R, Calos MP. "Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31." Genetics. 2004;166:1775-1782. Abstract
Derksen PWB, Tjin E, Meijer HP, et al. "Illegitimate WNT signaling promotes proliferation of multiple myeloma cells." Proc Natl Acad Sci U S A. 2004;101:6122-6127. Abstract
Logan CY, Nusse R. "The Wnt signaling pathway in development and disease." Annu Rev Cell Dev Biol. 2004;20:781-810. Abstract
2003
Chen W, ten Berge D, Brown J, et al. "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4." Science. 2003;301:1391-1394. Abstract