@article {cite-key, title = {Beta-catenin: a key mediator of Wnt signaling.}, journal = {Curr Opin Genet Dev}, volume = {8}, number = {1}, year = {1998}, month = {Feb}, pages = {95{\textendash}102}, address = {Howard Hughes Medical Institute, Department of Developmental Biology, Backman Center, Stanford University Medical Center, California 94305, USA. willert@cmgm.stanford.edu}, abstract = {Beta-catenin is a pivotal player in the signaling pathway initiated by Wnt proteins, mediators of several developmental processes. beta-catenin activity is controlled by a large number of binding partners that affect the stability and the localization of beta-catenin and is thereby able to participate in such varying processes as gene expression and cell adhesion. Activating mutations in beta-catenin and in components regulating its stability can contribute to the formation of certain tumors.}, issn = {0959-437X (Print); 0959-437X (Linking)}, author = {Willert, K and Nusse, R} }