Publications

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2012
Nusse R. "Wnt signaling." Cold Spring Harbor perspectives in biology. 2012;4(5).
Clevers H, Nusse R. "Wnt/β-catenin signaling and disease." Cell. 2012;149(6):1192-205. Abstract
Edris B, Espinosa I, Mühlenberg T, et al. "ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour." The Journal of pathology. 2012;227(2):223-33. Abstract
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. "Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(2):370-7. Abstract
McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. "A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration." PloS one. 2012;6(11):e26993. Abstract
2011
Bowman A, Nusse R. "Location, location, location: FoxM1 mediates β-catenin nuclear translocation and promotes glioma tumorigenesis." Cancer cell. 2011;20(4):415-6. Abstract
Fancy SP, Harrington EP, Yuen TJ, et al. "Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination." Nature neuroscience. 2011;14(8):1009-16. Abstract
ten Berge D, Kurek D, Blauwkamp T, et al. "Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells." Nature cell biology. 2011;13(9):1070-5. Abstract
2009
Wright TM, Brannon AR, Gordan JD, et al. "Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma." Oncogene. 2009;28:2513-2523. Abstract
2008
Leucht P, Minear S, ten Berge D, Nusse R, Helms JA. "Translating insights from development into regenerative medicine: the function of Wnts in bone biology." Semin Cell Dev Biol. 2008;19:434-443. Abstract
Nusse R, Fuerer C, Ching W, et al. "Wnt signaling and stem cell control." Cold Spring Harb Symp Quant Biol. 2008;73:59-66. Abstract
2006
Mikels AJ, Nusse R. "Wnts as ligands: processing, secretion and reception." Oncogene. 2006;25:7461-7468. Abstract
2001
Nusse R. "Developmental biology. Making head or tail of Dickkopf." Nature. 2001;411:255-256.
Wilson SI, Rydstrom A, Trimborn T, et al. "The status of Wnt signalling regulates neural and epidermal fates in the chick embryo." Nature. 2001;411:325-330. Abstract
Roberts RJ, Varmus HE, Ashburner M, et al. "Information access. Building a "GenBank" of the published literature." Science. 2001;291:2318-2319.
Rousset R, Mack JA, Wharton JKA, et al. "Naked cuticle targets dishevelled to antagonize Wnt signal transduction." Genes Dev. 2001;15:658-671. Abstract
Nusse R. "An ancient cluster of Wnt paralogues." Trends Genet. 2001;17:443.
2000
Rulifson EJ, Wu CH, Nusse R. "Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless." Mol Cell. 2000;6:117-126. Abstract
Reya T, O'Riordan M, Okamura R, et al. "Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism." Immunity. 2000;13:15-24. Abstract
Nusse R, Rulifson E, Fish M, et al. "Interactions between wingless and frizzled molecules in Drosophila." Ernst Schering Res Found Workshop. 2000:1-11.
1999
Willert K, Logan CY, Arora A, Fish M, Nusse R. "A Drosophila Axin homolog, Daxin, inhibits Wnt signaling." Development. 1999;126:4165-4173. Abstract
Bhanot P, Fish M, Jemison JA, Nusse R, Nathans J, Cadigan KM. "Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development." Development. 1999;126:4175-4186. Abstract
Millar SE, Willert K, Salinas PC, et al. "WNT signaling in the control of hair growth and structure." Dev Biol. 1999;207:133-149. Abstract
Willert K, Shibamoto S, Nusse R. "Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex." Genes Dev. 1999;13:1768-1773. Abstract
Nusse R. "WNT targets. Repression and activation." Trends Genet. 1999;15:1-3. Abstract