Publications

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2020
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
2012
Chai R, Kuo B, Wang T, et al. "Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(21):8167-72. Abstract
2011
Fancy SP, Harrington EP, Yuen TJ, et al. "Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination." Nature neuroscience. 2011;14(8):1009-16. Abstract
2008
Groen RWJ, Oud MECM, Schilder-Tol EJM, et al. "Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies." Cancer Res. 2008;68:6969-6977. Abstract
2004
Derksen PWB, Tjin E, Meijer HP, et al. "Illegitimate WNT signaling promotes proliferation of multiple myeloma cells." Proc Natl Acad Sci U S A. 2004;101:6122-6127. Abstract
2000
Reya T, O'Riordan M, Okamura R, et al. "Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism." Immunity. 2000;13:15-24. Abstract
1990
Nusse R, Theunissen H, Wagenaar E, et al. "The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus." Mol Cell Biol. 1990;10:4170-4179. Abstract
1986
Rijsewijk FA, van Lohuizen M, van Ooyen A, Nusse R. "Construction of a retroviral cDNA version of the int-1 mammary oncogene and its expression in vitro." Nucleic Acids Res. 1986;14:693-702. Abstract
1985
Nusse R, van Ooyen A, Rijsewijk F, van Lohuizen M, Schuuring E, van't Veer L. "Retroviral insertional mutagenesis in murine mammary cancer." Proc R Soc Lond B Biol Sci. 1985;226:3-13. Abstract
van Ooyen A, Kwee V, Nusse R. "The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences." EMBO J. 1985;4:2905-2909. Abstract
1984
van 't Veer LJ, van Kessel AG, van Heerikhuizen H, van Ooyen A, Nusse R. "Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis." Mol Cell Biol. 1984;4:2532-2534. Abstract
van Ooyen A, Nusse R. "Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact." Cell. 1984;39:233-240. Abstract
Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. "Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15." Nature. 1984;307:131-136. Abstract
1983
van Ooyen AJ, Michalides RJ, Nusse R. "Structural analysis of a 1.7-kilobase mouse mammary tumor virus-specific RNA." J Virol. 1983;46:362-370. Abstract
Michalides R, van Ooyen A, Nusse R. "Mouse mammary tumor virus expression and mammary tumor development." Curr Top Microbiol Immunol. 1983;106:57-78.