Location, location, location: FoxM1 mediates β-catenin nuclear translocation and promotes glioma tumorigenesis.

TitleLocation, location, location: FoxM1 mediates β-catenin nuclear translocation and promotes glioma tumorigenesis.
Publication TypeJournal Article
Year of Publication2011
AuthorsBowman A, Nusse R
JournalCancer cell
Volume20
Issue4
Pagination415-6
Date Published2011 Oct 18
ISSN1535-6108
AbstractGenetic alterations in the Wnt/β-catenin/TCF-signaling pathway are commonly found in human tumors, but not in glioblastomas. In this issue of Cancer Cell, Zhang et al. report that FoxM1 mediates β-catenin nuclear translocation in glioblastoma, suggesting a novel mechanism for glioblastoma progression in the absence of conventional Wnt/β-catenin pathway activation.
URLhttp://linkinghub.elsevier.com/retrieve/pii/S1535-6108(11)00362-X
DOI10.1016/j.ccr.2011.10.003
Short TitleCancer Cell