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Myb World

The Lipsick Laboratory

at Stanford University

   

Our laboratory studies the structure and function of chromosomes
and chromatin in metazoans.  The Myb protein family provides us
with a useful window for exploring chromosome and chromatin biology.
Proteins that contain Myb domains regulate gene expression, epigenetic
inheritance, nucleosome assembly and remodeling, histone modification,
telomere maintenance, and centromere identity.

 

 

 

Left: Wen H, Andrejka L, Ashton J, Karess R, and Lipsick JS.
 Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF
 via the Myb-MuvB/dREAM complex.
Genes & Development 22: 601-14. (2008)

 

 

Right: Sim CK, Perry S, Tharadra SK, Lipsick JS, and Ray A. 2012.
Epigenetic regulation of olfactory receptor gene expression by the Myb–MuvB/dREAM complex.
Genes & Development 26: 2483-98. (2012)

 

For information about courses taught by Joe Lipsick, click HERE.