Our laboratory studies the structure and function of
chromosomes and chromatin in metazoans. The Myb protein family provides us with a useful
window for exploring chromosome and chromatin biology. Proteins that contain Myb
domains regulate gene expression,
nucleosome assembly and remodeling, histone modification, telomere maintenance, and
centromere identity.

Wen,
H., Andrejka, L., Ashton, J., Karess, R., and Lipsick, J.S. 2008.
Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF
via the Myb-MuvB/dREAM complex. Genes & Development 22: 601-14.
For
information about courses taught by Joe Lipsick, click HERE.