Hi My daughter was born with Alobar Holoprosencephaly, with midline cleft. She died during 1991. I did plenty of research on Holoprosencephaly with the assistance of a very hard to find book titled HOLOPROSENCEPHALY AN OVERVIEW AND ATLAS OF CASES. The definitive source of information about Holoprosencephaly. Perhaps someone else can benefit from this book now. Please follow the link provided http://cgi.ebay.ca/ws/eBayISAPI.dll?ViewItem&item=7008983810&rd=1&sspagename=STRK%3AMESE%3AIT&rd=1 Have a nice day.....my thoughts are with you all. Douglas Matthews