What's New at the HOPES site
The HOPES site was created on September 22, 2001.
The following are the most recent additions:
Notice: this page is no longer being updated. For more recent additions to the HOPES website, click here .
New: An audio recording of "Population Genetics and HD"
11/4/2007
New: An audio recording of "The Basics of Huntington's Disease"
11/4/2007
Research Frontiers - Johns Hopkins Center of Excellence
11/4/2007
GINA (Genetic Information Non-Discrimination Act) Update - An important update on GINA's status in the US Senate
9/3/2007
Cholesterol and HD – an investigation into how HD affects cholesterol homeostasis
6/28/2007
The HD Pipeline – Research and Drug Development for Huntington’ Disease
6/15/2007
Dimebon - A known anti-inflammatory shows promise in preventing glutamate excitotoxicity and preserving normal levels of acetylcholine .
6/15/2007
The Mediterranean Diet and HD
5/11/2007
Couple Relationships and HD Testing
5/11/2007
Stories of HOPES - A series of fictional short stories inspired by the experiences of families living with HD
4/30/2007
Research Frontiers - Interview with Dr. Ron Kopito and Dr. Brigit Riley at Stanford
4/30/2007
HDSA Centers of Excellence - A discussion of what it means to be an HDSA "Center of Excellence"
4/30/2007
The Scientific Method - A layperson's guide
4/30/2007
HD Advocacy - The Genetic Information Non-Discrimination Act (GINA)
4/30/2007
Lifestyle and HD -
Driving and HD - 11/20/2006
Disease Mechanisms - Miscellaneous -
The Heat-Shock Response - 8/13/2006
Research Frontiers, Chapter 5 - HDSA Center of Excellence at Columbia University Visit: New York State Psychiatric Institute - 8/13/2006
Update - Coenzyme Q10 - An Antioxidant Drug - 7/31/2006
Update - An Introduction to DNA and Chromosomes -A closer look at what makes up the human genome... - 7/27/2006
Motor Symptoms - The motor changes associated with Huntington’s disease - 7/17/2006
Research Frontiers, Chapter 1, Section 2 - Dr. Diana Rosas, Massachusetts General Hospital - 07/12/06
Caspase-6 inhibition - How caspase-6 inhibition may prevent the development of HD - 07/06/06 Gene Regulation - How over-activation of p53 causes neurodegeneration - 07/04/06 Meditation and HD - A look at how meditation may delay the onset of many symptoms of HD - 06/29/06 Physical Exercise and HD - A chapter discussing how exercise can improve the quality of life of HD patients - 06/29/06 Research Frontiers, Chapter 4 - Dr. Rick Morimoto, Northwestern University - 03/28/06 Reduced Serotonin Signaling - A look at a class of drugs that may alleviate symptoms associated with HD - 02/19/06 An Introduction to Proteins - How proteins are made and what they look like - 02/12/06 Research Frontiers - HDSA Center of Excellence Site Visit: Washington University Medical Center in St. Louis, MO - 02/06/06 Tetrabenazine (TBZ) - A promising new drug used to treat chorea and other movement disorders - 01/25/06 Dietary Restriction - A look at how eating less can benefit the body’s cells and combat neurological disease - 01/06/06 Miraxion (LAX-101) - A drug that inhibits harmful enzymes and protects nerve cell membranes - 01/04/06 BDNF - An important neurotrophic factor - 01/04/06 Folic Acid - Natural prevention for Neurodegeneration? - 08/30/05 Mithramycin - A Gene Transcription Regulator - 08/11/05 Genetic Testing, Part 13 - The science and practice of testing for Huntington's disease - 08/11/05 Lifestyle and HD - An Introduction to Life Practices That Promote Health - 08/11/05 Arginine and Huntington's Disease - 07/20/05 Research Frontiers, Chapter 2 - Dr. Elena Cattaneo, University of Milan - 05/30/05 Vitamin E - An antioxidant drug - 05/06/05 The Facts of Life - An Introduction to Genetics for Grades 5-9 - 05/04/05 (Flash version) Memantine - An Anti-Glutamate Drug - 05/04/05 Fatty Acids - How fat consumption can influence the course of HD - 05/03/05 Stress & HD - A look into the possible effects of stress on people with HD - 04/27/05 The HOPES Timeline - A Brief History of Huntington's Disease - 04/19/05 (Non-Flash version) The HOPES Timeline - A Brief History of Huntington's Disease - 04/06/05 (Flash version) The HOPES Treatments Scorecard - A summary of drugs or treatments in various phases of research - 04/01/05 Red wine - A look at how resveratrol, a component of red wine, may be used to treat HD - 01/18/05 Sitemap - 01/10/05 (new version) Research in Progress - Selected Huntington's Disease Research Updates - 01/07/05 (update only: adding pages ae9 , ae10 , ae11 , ae12 , ae13 , ae14 , ae15 , ae16 , ae17 , ae18 , ae19 , ae20 , ae21 , ae22 , ae23 , ae24 , ae25 , ae26 , ae27 , ae28 , ae29 , ae30 , ae31 , ae32 , ae33 , ae34 , ae35 and ae36 ) Rapamycin - A Protein Build-up Remover - 01/05/05 Vitamin C - An antioxidant drug - 01/05/05 The Basics of Huntington's Disease - Video Versions, Segments 3 & 4 - 12/17/04 Research Frontiers - Research Methodologies - 12/15/04 Lamotrigine - An Anti-Glutamate and Anticonvulsant Drug - 12/08/04 Lipoic Acid - An Antioxidant Substance - 12/03/04 Selenium - An Antioxidant Dietary Supplement - 11/28/04 Cystamine - A Preventer of Protein Build-up - 11/26/04 (TUDCA) Tauroursodeoxycholic acid - Prevents early nerve cell death - 11/22/04 The Basics of Huntington's Disease - Spanish Translation (Español) - 11/21/04 Trehalose - A Protein Stabilizer - 11/19/04 RNA Interference (RNAi) - A gene silencing technique - 11/19/04 The Basics of Huntington's Disease - French Translation (traduction en Français) - 11/15/04 HOPES For Kids Games - Kids! Use your wits & knowledge of HD to complete these interactive puzzles! - 10/23/04 The Basics of Huntington's Disease - Video Versions, Segments 1 & 2 (more segments to come later) - 08/17/04 Last Modified: 04/05/2008
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