Arches. Photo by Daniel Chia
HOPES: Huntington's Outreach Project for Education, at Stanford
Nov
17
2010

trinucleotide repeat disorder

An illness in which there is an abnormally large number of repeats of a specific codon (sequence of three nucleotides that code for an amino acid). In HD, the repeated codon is C-A-G, which codes for the amino acid glutamine.  In addition to Huntington’s disease, other trinucleotide repeat disorders include fragile X syndrome and spinobulbar muscular atrophy.