Arches. Photo by Daniel Chia
HOPES: Huntington's Outreach Project for Education, at Stanford
Nov
27
2012

The Immune System and HD

            The human immune system consists of various cells circulating in blood and lymph vessels that can localize to sites of damage, injury, or infection and help in repairing damaged cells and destroying foreign or unhealthy substances. The immune system is complex, involving innate mechanisms such as inflammation and fever as well as adaptive mechanisms [...]

Jun
26
2010

Neurotrophic Factors and Huntington’s Disease

Neurotrophic factors are proteins that promote the development, maintenance and survival of neurons in the brain. These factors have been shown to increase the function of nerve cells as well as protect diseased neurons from dying. There are often higher levels of neurotrophic factors in areas with local neuronal damage, meaning that neurotrophic factors might [...]

Jun
26
2010

Neuroplasticity

Scientists once thought that the brain stopped developing after the first few years of life. They thought that connections formed between the brain’s nerve cells during an early “critical period” and then were fixed in place as we age. If connections between neurons developed only during the first few years of life, then only young [...]

Jun
26
2010

The Basic Neurobiology of Huntington’s Disease (Text and Audio)

Click on the link below to hear an audio recording of this article: The Neurobiology of Huntington’s Disease Now let’s look at the broader picture and ask a number of questions about the way in which the C-A-G triplet repeat in the genes of people with HD manifests itself in the symptoms of HD. We’ll [...]