Vitamin D has been called the “miracle vitamin” by many health experts due to mounting discoveries of its significance in promoting health and fighting numerous diseases, including cancer, heart disease, and diabetes. It may also be therapeutic for neurodegenerative diseases, which may be relevant to Huntington’s disease (HD). This particular vitamin is found in many [...]
It has long been known that melatonin, a hormone produced in the brain, plays an important role in regulating the body’s natural sleep-wake cycle by causing drowsiness and inducing sleep. The pineal gland, a small structure located beneath the center of the brain produces and releases melatonin in response to the intensity and type of [...]
Huntington’s disease (HD) is a genetic disease due to the abnormal CAG expansion of the mutated huntingtin gene. The mutated gene instructs cells in the body to produce a version of the huntingtin protein that ultimately leads to neuronal damage in the brain and creates the symptoms of HD. Currently, available HD therapies can only [...]
Learn about the different drugs and supplements for Huntington’s Disease through the following scorecard. You can browse through them by clicking on the category tabs and then clicking on the name of a drug or supplement. Print PDF
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Recent research has spotlighted retinoic acid (RA) as an intriguing possibility for further exploration as a treatment for Huntington’s disease. Retinoic acid is derived from a compound that we know as Vitamin A, which is fat-soluble and primarily found in two forms: retinol and carotenoids. Retinoic acid is synthesized in the body from retinol, which [...]
Drug Summary: Pridopidine, also known as Huntexil or ACR-16, is a dopamine stabilizer intended to improve voluntary movements and reduce chorea. Initial clinical trials – the MermaiHD and HART studies – show promising results, but drug regulation agencies have requested another trial before pridopidine can be sold to the general public. control relevant M. Hedlin, [...]
Welcome to the "Drugs and Supplements" section of the HOPES website! Articles within this section will frequently use the terms "treatment" and "cure." Please note, though, that the word "treatment" must not be confused with the word "cure," for there is currently no medical cure for Huntington's Disease (HD).
Serotonin (also known as 5-HT) is a neurotransmitter used to communicate important information between nerve cells. Serotonin is sometimes referred to as the “feel good” neurotransmitter owing to its association with elevated mood levels. It also has many other functions in the central nervous system including roles in sleep, depression, memory, pain, and aggression. Recent [...]